CA1036936A - New drug with antibacterial action - Google Patents
New drug with antibacterial actionInfo
- Publication number
- CA1036936A CA1036936A CA252,602A CA252602A CA1036936A CA 1036936 A CA1036936 A CA 1036936A CA 252602 A CA252602 A CA 252602A CA 1036936 A CA1036936 A CA 1036936A
- Authority
- CA
- Canada
- Prior art keywords
- les
- des
- amylase
- une
- new drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000000844 anti-bacterial effect Effects 0.000 title abstract 2
- 239000002547 new drug Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 claims abstract description 12
- 102000004139 alpha-Amylases Human genes 0.000 claims description 3
- 108090000637 alpha-Amylases Proteins 0.000 claims description 3
- 229940024171 alpha-amylase Drugs 0.000 claims description 3
- 239000004382 Amylase Substances 0.000 abstract description 8
- 102000013142 Amylases Human genes 0.000 abstract description 6
- 108010065511 Amylases Proteins 0.000 abstract description 6
- 235000019418 amylase Nutrition 0.000 abstract description 6
- YAAWASYJIRZXSZ-UHFFFAOYSA-N pyrimidine-2,4-diamine Chemical compound NC1=CC=NC(N)=N1 YAAWASYJIRZXSZ-UHFFFAOYSA-N 0.000 abstract description 2
- 229940124530 sulfonamide Drugs 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 5
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 description 4
- 239000002054 inoculum Substances 0.000 description 3
- QXJQHYBHAIHNGG-UHFFFAOYSA-N trimethylolethane Chemical compound OCC(C)(CO)CO QXJQHYBHAIHNGG-UHFFFAOYSA-N 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- XFMJUIKWKVJNDY-UHFFFAOYSA-N diethoxyphosphorylsulfanylmethylbenzene Chemical compound CCOP(=O)(OCC)SCC1=CC=CC=C1 XFMJUIKWKVJNDY-UHFFFAOYSA-N 0.000 description 2
- 229940088598 enzyme Drugs 0.000 description 2
- 241000588807 Bordetella Species 0.000 description 1
- 101100402341 Caenorhabditis elegans mpk-1 gene Proteins 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000588748 Klebsiella Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241001125929 Trisopterus luscus Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- CTAPFRYPJLPFDF-UHFFFAOYSA-N isoxazole Chemical compound C=1C=NOC=1 CTAPFRYPJLPFDF-UHFFFAOYSA-N 0.000 description 1
- APVPOHHVBBYQAV-UHFFFAOYSA-N n-(4-aminophenyl)sulfonyloctadecanamide Chemical compound CCCCCCCCCCCCCCCCCC(=O)NS(=O)(=O)C1=CC=C(N)C=C1 APVPOHHVBBYQAV-UHFFFAOYSA-N 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 229960005404 sulfamethoxazole Drugs 0.000 description 1
- NVBFHJWHLNUMCV-UHFFFAOYSA-N sulfamide Chemical compound NS(N)(=O)=O NVBFHJWHLNUMCV-UHFFFAOYSA-N 0.000 description 1
- JLKIGFTWXXRPMT-UHFFFAOYSA-N sulphamethoxazole Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 JLKIGFTWXXRPMT-UHFFFAOYSA-N 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229960001082 trimethoprim Drugs 0.000 description 1
- 108010050327 trypticase-soy broth Proteins 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7515038A FR2321283A1 (fr) | 1975-05-14 | 1975-05-14 | Medicament nouveau a activite antibacterienne |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1036936A true CA1036936A (en) | 1978-08-22 |
Family
ID=9155231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA252,602A Expired CA1036936A (en) | 1975-05-14 | 1976-05-14 | New drug with antibacterial action |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE841424A (enExample) |
| CA (1) | CA1036936A (enExample) |
| DE (1) | DE2617876A1 (enExample) |
| FR (1) | FR2321283A1 (enExample) |
| GB (1) | GB1503856A (enExample) |
| IL (1) | IL49563A (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2448903A1 (fr) * | 1979-02-19 | 1980-09-12 | Martin Henri | Medicament nouveau a base d'agents antimicrobiens, d'enzymes, d'anti-inflammatoires, d'anesthesique local, d'agents keratolytiques, d'agents mucolytiques et d'au moins un emulsionnant |
| JP2609434B2 (ja) * | 1992-11-16 | 1997-05-14 | ボリソビッチ レオニドフ，ニコライ | 抗菌性インターフェロン誘発性医薬品 |
| WO1994010977A1 (fr) * | 1992-11-16 | 1994-05-26 | Leonidov Nikolai B | Compose pharmaceutique anti-microbien et induisant des interferons |
| GB2327345B (en) * | 1997-07-18 | 1999-06-23 | Finnfeeds Int Ltd | Use of an enzyme for manufacturing an agent for controlling bacterial infection |
| FR2787331B1 (fr) * | 1998-12-22 | 2003-01-17 | Top Pharm Lab | Nouvelle formulation de comprimes a base d'alpha-amylase |
| CN105087520B (zh) * | 2014-05-21 | 2018-07-20 | 中国科学院上海生命科学研究院 | 一种促进重组极端耐热α-淀粉酶可溶性表达的方法 |
-
1975
- 1975-05-14 FR FR7515038A patent/FR2321283A1/fr active Granted
-
1976
- 1976-04-23 DE DE19762617876 patent/DE2617876A1/de not_active Withdrawn
- 1976-05-04 BE BE166699A patent/BE841424A/xx unknown
- 1976-05-12 IL IL49563A patent/IL49563A/xx unknown
- 1976-05-13 GB GB19803/76A patent/GB1503856A/en not_active Expired
- 1976-05-14 CA CA252,602A patent/CA1036936A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1503856A (en) | 1978-03-15 |
| IL49563A (en) | 1978-12-17 |
| IL49563A0 (en) | 1976-07-30 |
| FR2321283A1 (fr) | 1977-03-18 |
| FR2321283B1 (enExample) | 1978-08-04 |
| DE2617876A1 (de) | 1976-11-25 |
| BE841424A (fr) | 1976-11-04 |
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