CA1036600A - Synthese de diphenylthiazoles-4,5 substitues-2 - Google Patents

Synthese de diphenylthiazoles-4,5 substitues-2

Info

Publication number
CA1036600A
CA1036600A CA218,709A CA218709A CA1036600A CA 1036600 A CA1036600 A CA 1036600A CA 218709 A CA218709 A CA 218709A CA 1036600 A CA1036600 A CA 1036600A
Authority
CA
Canada
Prior art keywords
diphenylthiazole
produced
producing
obvious chemical
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA218,709A
Other languages
English (en)
Inventor
Enzo Marchetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Serono Laboratories Inc
Original Assignee
Serono Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serono Laboratories Inc filed Critical Serono Laboratories Inc
Application granted granted Critical
Publication of CA1036600A publication Critical patent/CA1036600A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA218,709A 1974-01-31 1975-01-27 Synthese de diphenylthiazoles-4,5 substitues-2 Expired CA1036600A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH137774A CH587836A5 (fr) 1974-01-31 1974-01-31

Publications (1)

Publication Number Publication Date
CA1036600A true CA1036600A (fr) 1978-08-15

Family

ID=4208998

Family Applications (1)

Application Number Title Priority Date Filing Date
CA218,709A Expired CA1036600A (fr) 1974-01-31 1975-01-27 Synthese de diphenylthiazoles-4,5 substitues-2

Country Status (15)

Country Link
JP (1) JPS50121269A (fr)
AT (1) AT339898B (fr)
BE (1) BE825097A (fr)
CA (1) CA1036600A (fr)
CH (1) CH587836A5 (fr)
DE (1) DE2503436A1 (fr)
DK (1) DK33175A (fr)
ES (1) ES434151A1 (fr)
FR (1) FR2259603B1 (fr)
GB (1) GB1490771A (fr)
IL (1) IL46476A (fr)
NL (1) NL7501086A (fr)
NO (1) NO750278L (fr)
SE (1) SE7501010L (fr)
ZA (1) ZA75494B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168315A (en) * 1977-09-28 1979-09-18 The Upjohn Company Dianisyl thiazole compound, compositions and method of antithrombotic treatment
JPH0753666B2 (ja) * 1987-09-14 1995-06-07 久光製薬株式会社 置換ジフェニルチアゾール誘導体からなる抗炎症剤
CA2012716A1 (fr) * 1989-03-22 1990-09-22 Akito Tanaka Composes de thiazole, procede de preparation et compose pharmaceutique les contenant
EP0592664B1 (fr) * 1991-03-07 2000-07-05 Hisamitsu Pharmaceutical Co., Inc. Derives de diphenylthiazole ayant une activite antiinflammatoire
EP1591443B1 (fr) 2003-02-07 2010-08-25 Daiichi Sankyo Company, Limited Derive de pyrazole
EP3162798B1 (fr) * 2007-09-28 2021-04-14 Takeda Pharmaceutical Company Limited Nouveaux composés hétérocycliques à 5 chaînons

Also Published As

Publication number Publication date
SE7501010L (fr) 1975-08-01
NL7501086A (nl) 1975-08-04
NO750278L (fr) 1975-08-25
AU7747875A (en) 1976-07-22
CH587836A5 (fr) 1977-05-13
JPS50121269A (fr) 1975-09-23
FR2259603B1 (fr) 1978-07-21
ES434151A1 (es) 1976-12-01
IL46476A0 (en) 1975-04-25
GB1490771A (en) 1977-11-02
IL46476A (en) 1978-12-17
ATA55975A (de) 1977-03-15
FR2259603A1 (fr) 1975-08-29
DE2503436A1 (de) 1975-08-07
AT339898B (de) 1977-11-10
ZA75494B (en) 1976-01-28
BE825097A (fr) 1975-07-31
DK33175A (fr) 1975-09-29

Similar Documents

Publication Publication Date Title
CA1087205A (fr) Acides 2-amino-3-(5-et 6-)benzoylphenylacetiques, leurs esters et sels metalliques
US4820828A (en) Cinnamohydroxamic acids
US3072653A (en) 5-amino derivatives of 4-thiazolidinones and process therefor
FR2471968A1 (fr) Ethers basiques, leur procede de preparation et compositions pharmaceutiques les contenant
EP0211363A2 (fr) Dérivés de 3-phénylthiométhylstyrène, procédé pour leur préparation et des agents antiallergiques et agent inhibitant la tyrosinekinase les contenant
CA1036600A (fr) Synthese de diphenylthiazoles-4,5 substitues-2
JPH072770A (ja) 新規な置換インドール類、その製造法及びそのインドール類を含有する製剤組成物
US4086349A (en) Quinolopyran-4-one-2-carboxylic acid derivatives and salts thereof as novel compounds and as medicines for treatment of allergic asthma
US4001228A (en) 2-thiol-4,5-diphenyloxazole s-derivatives
EP0093521A2 (fr) Dérivés de la quinoléine
US4054652A (en) Dihydro- and tetrahydro- iminothiazines
FI79303C (fi) Foerfarande foer framstaellning av terapeutiskt aktiva 2-piperazinylkinazolinderivat.
SU428602A3 (ru) Способ получения основпозамещенных производных 1
US4325886A (en) Optical resolution of acylthiopropionic acid
US3657243A (en) Pyridazone compounds and process for their production
CA2052544A1 (fr) Thieno [2,3-b] [1,4] thiazine-6-sulfonamides a substituants qui servent d'agents contre le glaucome
US4517365A (en) Isocarbostyril derivative
US2694069A (en) Basic esters of hydroxy-and alkoxy-substituted phenyloxoalkenoic acids and their salts
US3647802A (en) 2-amino-4-aryl-3 4-dihydroquinolines
US4742068A (en) Dihydropyridine compounds having 1,4,4-trisubstitution useful as antihypertensive agents
US4169899A (en) Penicillamine compounds
US3182063A (en) Substituted 4-thiazolidinones and process therefor
US3846412A (en) Dihydro-2-amino-isoquinolines and their derivatives
US4069230A (en) Preparation of indole derivatives
US4725306A (en) Pyridinecarboxamide plant growth inhibitors