CA1035700A - Preparation of stable virus - Google Patents

Preparation of stable virus

Info

Publication number
CA1035700A
CA1035700A CA191,632A CA191632A CA1035700A CA 1035700 A CA1035700 A CA 1035700A CA 191632 A CA191632 A CA 191632A CA 1035700 A CA1035700 A CA 1035700A
Authority
CA
Canada
Prior art keywords
preparation
stable virus
virus
stable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA191,632A
Other languages
English (en)
French (fr)
Other versions
CA191632S (en
Inventor
Nathan Zygraich
Julien Peetermans
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RECHERCHE ET INDUSTRIE THERAPEUTIQUES RIT
Original Assignee
RECHERCHE ET INDUSTRIE THERAPEUTIQUES RIT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RECHERCHE ET INDUSTRIE THERAPEUTIQUES RIT filed Critical RECHERCHE ET INDUSTRIE THERAPEUTIQUES RIT
Application granted granted Critical
Publication of CA1035700A publication Critical patent/CA1035700A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16351—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16751—Methods of production or purification of viral material
CA191,632A 1973-02-09 1974-02-04 Preparation of stable virus Expired CA1035700A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US330912A US3915794A (en) 1973-02-09 1973-02-09 Stabilizing compositions for cell-free viruses and cell-free virus preparations containing them

Publications (1)

Publication Number Publication Date
CA1035700A true CA1035700A (en) 1978-08-01

Family

ID=23291840

Family Applications (1)

Application Number Title Priority Date Filing Date
CA191,632A Expired CA1035700A (en) 1973-02-09 1974-02-04 Preparation of stable virus

Country Status (18)

Country Link
US (1) US3915794A (xx)
JP (1) JPS5732043B2 (xx)
AT (1) AT331398B (xx)
BE (1) BE810555A (xx)
CA (1) CA1035700A (xx)
CH (1) CH592143A5 (xx)
DD (1) DD110306A5 (xx)
DE (1) DE2406167C2 (xx)
DK (1) DK134032B (xx)
ES (1) ES422961A1 (xx)
FR (1) FR2216997B1 (xx)
GB (1) GB1452344A (xx)
HU (1) HU169120B (xx)
IE (1) IE38825B1 (xx)
IL (1) IL44011A (xx)
NL (1) NL178013C (xx)
SE (1) SE427799B (xx)
ZA (1) ZA74163B (xx)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57114527A (en) * 1979-10-29 1982-07-16 Merck & Co Inc Vaccine stabilizer
PT71926B (en) * 1979-10-29 1982-03-31 Merck & Co Inc Process for preparing a liquid vaccine comprising a stabilizer
US4273762A (en) * 1979-12-03 1981-06-16 Merck & Co., Inc. Lyophilization process for live viral compositions
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
ZA874625B (en) * 1986-06-30 1988-10-26 Smith Kline Rit Stabilizers for live vaccines,process for their preparation and vaccines containing them
US4847078A (en) * 1987-01-14 1989-07-11 Arseco, Inc. Storage stable topical composition having moisture control agent
JPH01112853U (xx) * 1988-01-27 1989-07-28
IL90188A0 (en) * 1988-05-18 1989-12-15 Cryopharm Corp Process and medium for the lyophilization of erythrocytes
US5045446A (en) * 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
CA2062941A1 (en) * 1990-05-25 1991-11-26 Raymond P. Goodrich, Jr. Process for lyophilizing cells, cell-like materials and platelets in a mixture of biocompatable amphipathic polymers
CA2075521C (en) * 1992-05-05 1995-11-28 Kuniaki Koyama Stabilized live vaccine
RO114906B1 (ro) * 1992-06-04 1999-08-30 Merck & Co Inc Procedeu pentru producerea vaccinului virus varicela zoster (vzv) atenuat
US5360736A (en) * 1992-06-04 1994-11-01 Merck & Co., Inc. Process for attenuated varicella zoster virus vaccine production
CA2158935A1 (en) * 1993-10-12 1995-04-20 Chiron Viagene, Inc. Methods for preserving recombinant viruses
ZA973642B (en) * 1996-04-26 1997-11-25 Merck & Co Inc DNA vaccine formulations.
AU727306B2 (en) * 1996-04-26 2000-12-07 Merck Sharp & Dohme Corp. DNA vaccine formulations
US6051238A (en) * 1996-12-20 2000-04-18 Merck & Co., Inc. Stabilizers for lyophilized mumps vaccines
US6210683B1 (en) 1997-09-05 2001-04-03 Merck & Co., Inc. Stabilizers containing recombinant human serum albumin for live virus vaccines
DE19812940A1 (de) * 1998-03-24 1999-10-07 Medigene Ag Formulierung mit Papillomavirus-spezifischem Protein, seine Herstellung und Verwendung
US6926897B1 (en) * 1998-03-24 2005-08-09 Medigene Aktiengesellschaft Medicament for the avoidance or treatment of papillomavirus-specific tumour
GB9808922D0 (en) * 1998-04-24 1998-06-24 Cantab Pharmaceuticals Res Ltd Virus preparations
US6225289B1 (en) 1998-12-10 2001-05-01 Genvec, Inc. Methods and compositions for preserving adenoviral vectors
FR2814957B1 (fr) * 2000-10-06 2002-12-20 Aventis Pasteur Composition vaccinale et procede de stabilisation
US7013940B2 (en) * 2001-04-19 2006-03-21 Michelin Recherche Et Technique S.A. Device for attenuating cavity noise in a tire and wheel
DK1418942T3 (da) * 2001-12-10 2005-11-28 Bavarian Nordic As Poxvirus-holdige sammensætninger og fremgangsmåde til fremstilling deraf
TWI398272B (zh) 2005-03-08 2013-06-11 Intervet Int Bv 化學定義的安定劑
EP1870649A1 (en) 2006-06-20 2007-12-26 Octapharma AG Lyophilisation targetting defined residual moisture by limited desorption energy levels
LT2741740T (lt) 2011-08-12 2017-08-10 Merial, Inc. Biologinių produktų, ypatingai vakcinų, vakuuminis konservavimas
TWI690322B (zh) * 2012-10-02 2020-04-11 法商傳斯堅公司 含病毒的調配物及其使用
CA2948845C (en) 2014-05-14 2022-05-31 Merial, Inc. Methods for freeze-drying and rehydrating biologics
MX2017007178A (es) * 2014-12-01 2017-08-28 Transgene Sa Formulaciones liquidas estables de virus de vacuna.
CN105999287A (zh) * 2016-07-01 2016-10-12 广东圣戈生物科技有限公司 一种疫苗稀释液及其制备方法
BR112019006900A2 (pt) 2016-10-05 2019-07-02 Zoetis Services Llc métodos de liofilização que proporcionam protozoários desidratados estáveis para o uso como potentes vacinas vivas
US20200308550A1 (en) 2017-09-11 2020-10-01 Imba - Institut Für Molekulare Biotechnologie Gmbh Tumor organoid model

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1292803A (en) * 1968-11-18 1972-10-11 Nat Res Dev Improvements relating to the production of antigens
US3642574A (en) * 1970-04-29 1972-02-15 Us Agriculture Method for producing vaccine for immunization of poultry against marek{3 s disease
US3783098A (en) * 1971-08-10 1974-01-01 Cornell Res Foundation Inc Highly potent,viable and stable cellfree virus preparations from cells infected with cell-associated viruses and method for obtaining the same

Also Published As

Publication number Publication date
DD110306A5 (xx) 1974-12-12
IL44011A (en) 1977-04-29
JPS49109518A (xx) 1974-10-18
IE38825B1 (en) 1978-06-07
ZA74163B (en) 1974-11-27
NL7401786A (xx) 1974-08-13
DK134032B (da) 1976-08-30
AU6486574A (en) 1975-07-24
DE2406167C2 (de) 1984-12-20
NL178013C (nl) 1986-01-02
FR2216997A1 (xx) 1974-09-06
US3915794A (en) 1975-10-28
FR2216997B1 (xx) 1978-01-06
SE427799B (sv) 1983-05-09
DE2406167A1 (de) 1974-08-15
CH592143A5 (xx) 1977-10-14
DK134032C (xx) 1977-02-07
ATA98274A (de) 1975-11-15
GB1452344A (en) 1976-10-13
IE38825L (en) 1974-08-09
JPS5732043B2 (xx) 1982-07-08
ES422961A1 (es) 1976-06-01
HU169120B (xx) 1976-09-28
IL44011A0 (en) 1974-05-16
NL178013B (nl) 1985-08-01
AT331398B (de) 1976-08-25
BE810555A (fr) 1974-08-05

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