CA1027563A - Phenothiazine derivatives, compositions thereof and methods of preparation thereof - Google Patents

Phenothiazine derivatives, compositions thereof and methods of preparation thereof

Info

Publication number
CA1027563A
CA1027563A CA201,508A CA201508A CA1027563A CA 1027563 A CA1027563 A CA 1027563A CA 201508 A CA201508 A CA 201508A CA 1027563 A CA1027563 A CA 1027563A
Authority
CA
Canada
Prior art keywords
compositions
preparation
methods
phenothiazine derivatives
phenothiazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA201,508A
Other languages
English (en)
French (fr)
Other versions
CA201508S (en
Inventor
Niels Lassen
Jorn L.M. Buus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kefalas AS
Original Assignee
Kefalas AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kefalas AS filed Critical Kefalas AS
Application granted granted Critical
Publication of CA1027563A publication Critical patent/CA1027563A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CA201,508A 1973-06-08 1974-06-03 Phenothiazine derivatives, compositions thereof and methods of preparation thereof Expired CA1027563A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2752773A GB1460713A (en) 1973-06-08 1973-06-08 7-fluoro substituted phenothiazines method for preparation thereof and compositions bladed rotor for a gas turbine engine

Publications (1)

Publication Number Publication Date
CA1027563A true CA1027563A (en) 1978-03-07

Family

ID=10261046

Family Applications (1)

Application Number Title Priority Date Filing Date
CA201,508A Expired CA1027563A (en) 1973-06-08 1974-06-03 Phenothiazine derivatives, compositions thereof and methods of preparation thereof

Country Status (17)

Country Link
US (1) US3966930A (cs)
JP (1) JPS5025574A (cs)
AT (1) AT333296B (cs)
BE (1) BE816128A (cs)
CA (1) CA1027563A (cs)
CH (1) CH610317A5 (cs)
DE (1) DE2426149C3 (cs)
DK (1) DK308174A (cs)
ES (1) ES427079A1 (cs)
FI (1) FI55335C (cs)
FR (1) FR2232324B1 (cs)
GB (1) GB1460713A (cs)
IE (1) IE39278B1 (cs)
NL (1) NL7407643A (cs)
NO (1) NO141649C (cs)
SE (1) SE407939B (cs)
ZA (1) ZA743407B (cs)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1540842A (en) * 1976-08-25 1979-02-14 Kefalas As Phenothiazines
JPS55111483A (en) * 1979-02-22 1980-08-28 Eisai Co Ltd Novel phenothiazine derivative and psychotropic drug comprising it
FR2691459B1 (fr) * 1992-05-25 1995-06-09 Adir Nouveaux derives de la phenothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
CA2461663A1 (en) * 2001-09-27 2003-04-03 Ramot At Tel Aviv University Ltd. Conjugated anti-psychotic drugs and uses thereof
US7544681B2 (en) * 2001-09-27 2009-06-09 Ramot At Tel Aviv University Ltd. Conjugated psychotropic drugs and uses thereof
AU2004201240B2 (en) * 2001-09-27 2008-08-07 Bar Ilan University Conjugated Psychotropic Drugs and Uses Thereof
JP5284779B2 (ja) * 2005-06-07 2013-09-11 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド コンジュゲート化された向精神薬の新規な塩およびその調製方法
AU2007274583B2 (en) 2006-07-17 2012-11-01 Bar-Ilan University Conjugates comprising a psychotropic drug or a GABA agonist and an organic acid and their use in treating pain and other CNS disorders
WO2009101616A1 (en) 2008-02-11 2009-08-20 Ramot At Tel Aviv University Ltd. Novel conjugates for treating neurodegenerative diseases and disorders
US8975251B2 (en) 2009-12-09 2015-03-10 Bar-Ilan University Methods of improving cognitive functions
CN102858345A (zh) 2010-02-24 2013-01-02 雷蒙特亚特特拉维夫大学有限公司 奋乃静-gaba的三甲磺酸盐的晶型及其制备方法
WO2012038963A1 (en) 2010-09-22 2012-03-29 Ramot At Tel-Aviv University Ltd. An acid addition salt of a nortriptyline-gaba conjugate and a process of preparing same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3004028A (en) * 1961-10-10 Preparation of phenothiazines
NL108827C (cs) * 1956-04-09
NL227699A (cs) * 1957-09-11 1900-01-01
FR1212031A (fr) * 1957-10-21 1960-03-21 Rhone Poulenc Sa Dérivés de la phénothiazine substitués à l'azote par une chaîne basique comportant un hétérocycle et leur préparation
US2945030A (en) * 1958-07-24 1960-07-12 Smith Kline French Lab Substituted aralkyl phenothiazinylalkyl piperazines
NL251370A (cs) * 1959-05-08
US3169962A (en) * 1963-02-28 1965-02-16 Olin Mathieson Benzhydryl ethers of 10-(hydroxyethylpiperazinopropyl) phenothiazines
US3419553A (en) * 1966-05-25 1968-12-31 Squibb & Sons Inc Fluorinated phenothiazine compounds
BE787967A (fr) * 1971-08-25 1973-02-26 May & Baker Ltd Derives de la phenothiazine antispastiques

Also Published As

Publication number Publication date
CH610317A5 (cs) 1979-04-12
AT333296B (de) 1976-11-10
FR2232324B1 (cs) 1977-11-04
FI55335C (fi) 1979-07-10
AU6931574A (en) 1975-11-27
DE2426149C3 (de) 1980-10-09
IE39278L (en) 1974-12-08
NO141649B (no) 1980-01-07
BE816128A (fr) 1974-12-10
ZA743407B (en) 1975-06-25
FI173574A (cs) 1974-12-09
SE7407518L (cs) 1974-12-09
FI55335B (fi) 1979-03-30
NO742075L (cs) 1975-01-06
JPS5025574A (cs) 1975-03-18
US3966930A (en) 1976-06-29
NL7407643A (cs) 1974-12-10
FR2232324A1 (cs) 1975-01-03
IE39278B1 (en) 1978-09-13
SE407939B (sv) 1979-04-30
GB1460713A (en) 1977-01-06
ES427079A1 (es) 1976-07-16
ATA457374A (de) 1976-03-15
DE2426149B2 (de) 1980-01-31
DE2426149A1 (de) 1975-01-02
NO141649C (no) 1980-04-16
DK308174A (cs) 1975-02-03

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