CA1026348A - Carbazoles - Google Patents

Carbazoles

Info

Publication number
CA1026348A
CA1026348A CA177,061A CA177061A CA1026348A CA 1026348 A CA1026348 A CA 1026348A CA 177061 A CA177061 A CA 177061A CA 1026348 A CA1026348 A CA 1026348A
Authority
CA
Canada
Prior art keywords
carbazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA177,061A
Other languages
English (en)
French (fr)
Inventor
Leo Berger
Alfred J. Corraz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1026348A publication Critical patent/CA1026348A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA177,061A 1972-07-24 1973-07-23 Carbazoles Expired CA1026348A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27414272A 1972-07-24 1972-07-24

Publications (1)

Publication Number Publication Date
CA1026348A true CA1026348A (en) 1978-02-14

Family

ID=23046965

Family Applications (1)

Application Number Title Priority Date Filing Date
CA177,061A Expired CA1026348A (en) 1972-07-24 1973-07-23 Carbazoles

Country Status (26)

Country Link
JP (1) JPS5740144B2 (en, 2012)
KR (1) KR780000289B1 (en, 2012)
AR (1) AR205331A1 (en, 2012)
AT (1) AT325607B (en, 2012)
AU (1) AU475534B2 (en, 2012)
BE (1) BE802596A (en, 2012)
CA (1) CA1026348A (en, 2012)
CH (1) CH587819A5 (en, 2012)
DD (1) DD107681A5 (en, 2012)
DE (1) DE2337340C2 (en, 2012)
DK (1) DK138537B (en, 2012)
FI (1) FI59244C (en, 2012)
FR (1) FR2193611B1 (en, 2012)
GB (1) GB1385620A (en, 2012)
HK (1) HK49878A (en, 2012)
HU (1) HU167611B (en, 2012)
IE (1) IE37942B1 (en, 2012)
IL (1) IL42799A (en, 2012)
KE (1) KE2847A (en, 2012)
LU (1) LU68071A1 (en, 2012)
MY (1) MY7800315A (en, 2012)
NL (1) NL169877C (en, 2012)
NO (1) NO142865C (en, 2012)
SE (2) SE402283B (en, 2012)
SU (1) SU509220A3 (en, 2012)
ZA (1) ZA734047B (en, 2012)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005016882A1 (en) * 2003-08-15 2005-02-24 Universite Laval Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbazoles

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146542A (en) * 1978-06-12 1979-03-27 Hoffmann-La Roche Inc. Dihydrocarbazole acetic acid and esters thereof
US4150031A (en) * 1978-06-26 1979-04-17 Hoffmann-La Roche Inc. Hydroxy methyl carbazole acetic acid and esters
US4158007A (en) * 1978-08-21 1979-06-12 Hoffmann-La Roche Inc. Carbazole methyl malonates
US4501908A (en) * 1981-03-12 1985-02-26 Hoffmann-La Roche Inc. 2,3-Isopropylidene ribonic acid, 1,4-lactones
JPS6040256U (ja) * 1983-08-25 1985-03-20 伊東　璋 容器類洗浄機
DE3768097D1 (de) * 1986-01-23 1991-04-04 Merck Frosst Canada Inc Tetrahydrocarbazol-1-alkansaeuren.
ATE90076T1 (de) 1986-03-27 1993-06-15 Merck Frosst Canada Inc Tetrahydrocarbazole ester.
CA1326030C (en) * 1987-07-21 1994-01-11 John W. Gillard Cyclohept[b]indolealkanoic acids
EP0307077A1 (en) * 1987-07-21 1989-03-15 Merck Frosst Canada Inc. Tetrahydrocarbazoles for the improvement of cyclosporin therapy
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
US6013808A (en) * 1998-06-16 2000-01-11 Pfizer Inc. Method of purifying carbazole ester precursors of 6-chloro-α-methyl-carbazole-2-acetic acid
JP2004010601A (ja) * 2002-06-11 2004-01-15 Nippon Steel Chem Co Ltd インドール誘導体の製造方法及びそのための有用な中間体
US7332516B2 (en) 2003-01-14 2008-02-19 Merck + Co., Inc. Geminally di-substituted NSAID derivatives as Aβ42 lowering agents
JP5431647B2 (ja) * 2003-05-06 2014-03-05 エアー．プロダクツ．アンド．ケミカルス．インコーポレーテッド パイ共役基材の可逆的水素化による水素貯蔵
US7601856B2 (en) 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
PL2802320T3 (pl) * 2011-11-15 2019-09-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Związki tricykliczne, zawierające je kompozycje i ich zastosowania
JP5940036B2 (ja) * 2013-10-08 2016-06-29 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ
JPWO2021193708A1 (en, 2012) * 2020-03-25 2021-09-30

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD70880A (en, 2012) *
US3580926A (en) * 1969-11-10 1971-05-25 Parke Davis & Co Carbazole-4-alkanoic acids and tetrahydrocarbazole-4-alkanoic acids
ZA715217B (en) * 1970-08-20 1972-04-26 Org Nv Anti-inflammatory preparations

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005016882A1 (en) * 2003-08-15 2005-02-24 Universite Laval Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbazoles

Also Published As

Publication number Publication date
SE7605813L (sv) 1976-05-21
NL169877B (nl) 1982-04-01
SU509220A3 (ru) 1976-03-30
IE37942B1 (en) 1977-11-23
FI59244C (fi) 1981-07-10
KR780000289B1 (en) 1978-08-10
AU475534B2 (en) 1976-08-26
JPS4943973A (en, 2012) 1974-04-25
CH587819A5 (en, 2012) 1977-05-13
DK138537B (da) 1978-09-25
DE2337340C2 (de) 1985-05-02
DD107681A5 (en, 2012) 1974-08-12
BE802596A (fr) 1974-01-21
KE2847A (en) 1978-06-30
AT325607B (de) 1975-10-27
IE37942L (en) 1974-01-24
DE2337340A1 (de) 1974-02-14
IL42799A0 (en) 1973-10-25
MY7800315A (en) 1978-12-31
FR2193611A1 (en, 2012) 1974-02-22
AU5839073A (en) 1975-01-23
ZA734047B (en) 1974-03-27
LU68071A1 (en, 2012) 1975-04-11
JPS5740144B2 (en, 2012) 1982-08-25
DK138537C (en, 2012) 1979-03-05
IL42799A (en) 1977-03-31
AR205331A1 (es) 1976-04-30
FI59244B (fi) 1981-03-31
HU167611B (en, 2012) 1975-11-28
NL169877C (nl) 1982-09-01
NL7310275A (en, 2012) 1974-01-28
GB1385620A (en) 1975-02-26
ATA649773A (de) 1975-01-15
SE402283B (sv) 1978-06-26
HK49878A (en) 1978-09-08
NO142865B (no) 1980-07-28
NO142865C (no) 1980-11-05
FR2193611B1 (en, 2012) 1976-05-14

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