CA1026318A - Preparation process for spirolactone steroids - Google Patents

Preparation process for spirolactone steroids

Info

Publication number
CA1026318A
CA1026318A CA191,844A CA191844A CA1026318A CA 1026318 A CA1026318 A CA 1026318A CA 191844 A CA191844 A CA 191844A CA 1026318 A CA1026318 A CA 1026318A
Authority
CA
Canada
Prior art keywords
produit
représente
que
formule
par
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA191,844A
Other languages
English (en)
French (fr)
Other versions
CA191844S (en
Inventor
Julien Warnant
Jean Jolly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of CA1026318A publication Critical patent/CA1026318A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA191,844A 1973-02-06 1974-02-05 Preparation process for spirolactone steroids Expired CA1026318A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7304057A FR2216273B1 (ja) 1973-02-06 1973-02-06

Publications (1)

Publication Number Publication Date
CA1026318A true CA1026318A (en) 1978-02-14

Family

ID=9114388

Family Applications (1)

Application Number Title Priority Date Filing Date
CA191,844A Expired CA1026318A (en) 1973-02-06 1974-02-05 Preparation process for spirolactone steroids

Country Status (14)

Country Link
US (1) US3897417A (ja)
JP (1) JPS5829320B2 (ja)
AT (1) AT336811B (ja)
BE (1) BE810643A (ja)
CA (1) CA1026318A (ja)
CH (2) CH609710A5 (ja)
DK (1) DK134818B (ja)
ES (2) ES422921A1 (ja)
FR (1) FR2216273B1 (ja)
GB (1) GB1451843A (ja)
IE (1) IE39329B1 (ja)
LU (1) LU69328A1 (ja)
NL (1) NL179288C (ja)
SE (2) SE399270B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4058522A (en) * 1973-07-09 1977-11-15 Richter Gedeon Vegyeszeti Gyar Rt. Steroids effective against heavy-metal poisoning
IT1130924B (it) * 1980-03-06 1986-06-18 Secifarma Spa Procedimento per la preparazione di spironolattone micronizzato
US4501695A (en) * 1983-05-16 1985-02-26 The Upjohn Company Spironalactone process
ATE365171T1 (de) * 1995-12-11 2007-07-15 Searle Llc Verfahren zur herstellung einer epoxyverbindung
ES2293944T3 (es) 1996-12-11 2008-04-01 G.D. Searle Llc. Procedimiento de epoxidacion.
US6887991B1 (en) 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein
US7235655B2 (en) * 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
WO2003082895A2 (en) * 2002-03-22 2003-10-09 Pharmacia & Upjohn Company Process to prepare eplerenone
DE102005049393B4 (de) * 2005-10-15 2019-08-08 Kennametal Widia Produktions Gmbh & Co. Kg Verfahren zur Herstellung eines beschichteten Substratkörpers, Substratkörper mit einer Beschichtung und Verwendung des beschichteten Substratkörpers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1329570A (fr) * 1959-12-10 1963-06-14 Searle & Co Procédé de préparation des lactones d'alcanoylthio-17alpha-carboxyéthyl-17bêta-hydroxy-3-oxoandrostènes
US3257390A (en) * 1963-06-12 1966-06-21 Merck & Co Inc Ring a unsaturated 21-hydroxy-3-oxo-17alpha-pregnane-17-carboxylic acid lactone diuretic agents
US3300489A (en) * 1964-07-24 1967-01-24 Smith Kline French Lab Steroidal c-17 spirolactones and processes and intermediates used in the preparation thereof

Also Published As

Publication number Publication date
NL179288B (nl) 1986-03-17
US3897417A (en) 1975-07-29
AT336811B (de) 1977-05-25
JPS5829320B2 (ja) 1983-06-22
LU69328A1 (ja) 1974-09-25
SE399270B (sv) 1978-02-06
FR2216273B1 (ja) 1977-07-22
NL179288C (nl) 1986-08-18
SE440782B (sv) 1985-08-19
CH595399A5 (ja) 1978-02-15
IE39329L (en) 1974-08-06
AU6521174A (en) 1975-08-07
JPS49109365A (ja) 1974-10-17
CH609710A5 (ja) 1979-03-15
IE39329B1 (en) 1978-09-13
GB1451843A (en) 1976-10-06
NL7401656A (ja) 1974-08-08
ES422921A1 (es) 1976-09-16
ES444112A1 (es) 1977-08-16
FR2216273A1 (ja) 1974-08-30
SE7706509L (sv) 1977-06-03
DK134818B (da) 1977-01-24
BE810643A (fr) 1974-08-05
ATA92174A (de) 1976-09-15
DK134818C (ja) 1977-06-13

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