CA1025869A - Isoquinoline derivatives - Google Patents

Isoquinoline derivatives

Info

Publication number
CA1025869A
CA1025869A CA208,607A CA208607A CA1025869A CA 1025869 A CA1025869 A CA 1025869A CA 208607 A CA208607 A CA 208607A CA 1025869 A CA1025869 A CA 1025869A
Authority
CA
Canada
Prior art keywords
isoquinoline derivatives
isoquinoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA208,607A
Other languages
English (en)
French (fr)
Other versions
CA208607S (en
Inventor
Wolfgang Eberlein
Eberhard Kutter
Volkard Austel
Joachim Heider
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2345422A external-priority patent/DE2345422C2/de
Priority claimed from DE19732345423 external-priority patent/DE2345423A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Application granted granted Critical
Publication of CA1025869A publication Critical patent/CA1025869A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
CA208,607A 1973-09-08 1974-09-06 Isoquinoline derivatives Expired CA1025869A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2345422A DE2345422C2 (de) 1973-09-08 1973-09-08 Substituierte Isochinolyl-arylpiperazine diese enthaltende Arzneimittel sowie Verfahren zu deren Herstellung
DE19732345423 DE2345423A1 (de) 1973-09-08 1973-09-08 Neue substituierte phenylaethylaminderivate, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
CA1025869A true CA1025869A (en) 1978-02-07

Family

ID=25765764

Family Applications (1)

Application Number Title Priority Date Filing Date
CA208,607A Expired CA1025869A (en) 1973-09-08 1974-09-06 Isoquinoline derivatives

Country Status (26)

Country Link
US (1) US3948898A (it)
JP (1) JPS596868B2 (it)
AT (1) AT330777B (it)
BG (2) BG26195A4 (it)
CA (1) CA1025869A (it)
CH (2) CH605778A5 (it)
CS (1) CS185660B2 (it)
DD (1) DD115122A5 (it)
DK (1) DK137124C (it)
ES (3) ES429473A1 (it)
FI (1) FI52219C (it)
FR (1) FR2242979B1 (it)
GB (1) GB1446791A (it)
HK (1) HK4180A (it)
HU (1) HU167869B (it)
IE (1) IE40742B1 (it)
IL (1) IL45609A (it)
MY (1) MY8100330A (it)
NL (1) NL176363C (it)
NO (1) NO140978C (it)
PH (1) PH12918A (it)
PL (1) PL91712B1 (it)
RO (1) RO63655A (it)
SE (1) SE424863B (it)
SU (2) SU545256A3 (it)
YU (1) YU39928B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2639718A1 (de) * 1976-09-03 1978-03-16 Thomae Gmbh Dr K Neue phenylaethylamine
DE2702600A1 (de) * 1977-01-22 1978-07-27 Thomae Gmbh Dr K Neue aminoalkoxyphenyl-derivate
US4619930A (en) * 1985-01-16 1986-10-28 Bristol-Myers Company Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
JPS6312877U (it) * 1986-03-05 1988-01-27
US4876256A (en) * 1988-04-29 1989-10-24 Merck & Co., Inc. Alkylpiperazinylpyridines as hypoglycemic agents
US5169948A (en) * 1991-05-22 1992-12-08 American Home Products Corporation Process and intermediates for the preparation of spiro[isoquinoline-4(1H),3-pyrrolidine]1,2,3,5 (2H)-tetrones which are useful as aldose reductase inhibitors
SE9303274D0 (sv) * 1993-10-07 1993-10-07 Astra Ab Novel phenylethyl and phenylproplamines
WO1999021834A1 (en) 1997-10-27 1999-05-06 Neurosearch A/S Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors
US20040152710A1 (en) * 2002-10-15 2004-08-05 Deecher Darlene Coleman Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms
ATE517880T1 (de) * 2005-01-28 2011-08-15 Boehringer Ingelheim Pharma Verfahren zur herstellung von isochroman und derivaten davon
US7829713B2 (en) 2006-02-28 2010-11-09 Helicon Therapeutics, Inc. Therapeutic piperazines
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
EP4370110A1 (en) * 2021-07-16 2024-05-22 Denali Therapeutics Inc. Compounds, compositions and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1185934A (en) * 1967-06-28 1970-03-25 Pfizer & Co C Derivatives of 1,3(2H,4H)-Dioxoisoquinoline and preparation thereof
SE368009B (it) * 1971-09-16 1974-06-17 Kabi Ab
GB1424348A (en) * 1972-11-30 1976-02-11 Wyeth John & Brother Ltd Isoquinoline derivatives

Also Published As

Publication number Publication date
DK137124C (da) 1978-06-26
PL91712B1 (it) 1977-03-31
YU39928B (en) 1985-06-30
FR2242979A1 (it) 1975-04-04
IE40742L (en) 1975-03-08
BG26195A4 (it) 1979-02-15
JPS596868B2 (ja) 1984-02-15
IE40742B1 (en) 1979-08-15
ATA651474A (de) 1975-10-15
CS185660B2 (en) 1978-10-31
NL7411843A (nl) 1975-03-11
FI52219C (fi) 1977-07-11
HK4180A (en) 1980-02-08
HU167869B (it) 1975-12-25
NL176363B (nl) 1984-11-01
SU545256A3 (ru) 1977-01-30
IL45609A0 (en) 1974-11-29
MY8100330A (en) 1981-12-31
RO63655A (fr) 1978-10-15
FI52219B (it) 1977-03-31
NO743220L (it) 1975-04-07
NL176363C (nl) 1985-04-01
FR2242979B1 (it) 1978-02-03
YU239174A (en) 1982-06-30
DK137124B (da) 1978-01-23
BG22390A3 (it) 1977-02-20
ES433959A1 (es) 1976-11-16
ES433958A1 (es) 1976-11-16
NO140978C (no) 1979-12-19
PH12918A (en) 1979-10-10
DK472774A (it) 1975-05-05
SE7411312L (it) 1975-03-10
AU7302374A (en) 1976-03-11
SE424863B (sv) 1982-08-16
US3948898A (en) 1976-04-06
NO140978B (no) 1979-09-10
ES429473A1 (es) 1976-09-01
CH605778A5 (it) 1978-10-13
FI246574A (it) 1975-03-09
CH605779A5 (it) 1978-10-13
AT330777B (de) 1976-07-26
JPS5050381A (it) 1975-05-06
DD115122A5 (it) 1975-09-12
GB1446791A (en) 1976-08-18
SU538664A3 (ru) 1976-12-05
IL45609A (en) 1977-07-31

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