CA1009239A - Process for the manufacture of 2-arylamino-2-imidazoline derivatives and their salts - Google Patents

Process for the manufacture of 2-arylamino-2-imidazoline derivatives and their salts

Info

Publication number
CA1009239A
CA1009239A CA196,643A CA196643A CA1009239A CA 1009239 A CA1009239 A CA 1009239A CA 196643 A CA196643 A CA 196643A CA 1009239 A CA1009239 A CA 1009239A
Authority
CA
Canada
Prior art keywords
arylamino
salts
manufacture
imidazoline derivatives
imidazoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA196,643A
Other languages
English (en)
Other versions
CA196643S (en
Inventor
Rudolf Franzmair
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Patheon Austria GmbH and Co KG
Original Assignee
Chemie Linz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemie Linz AG filed Critical Chemie Linz AG
Application granted granted Critical
Publication of CA1009239A publication Critical patent/CA1009239A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA196,643A 1973-04-02 1974-04-02 Process for the manufacture of 2-arylamino-2-imidazoline derivatives and their salts Expired CA1009239A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2316377A DE2316377C3 (de) 1973-04-02 1973-04-02 Verfahren zur Herstellung von 2-Phenyl-amino-2-imidazolin-Derivaten und von deren Salzen

Publications (1)

Publication Number Publication Date
CA1009239A true CA1009239A (en) 1977-04-26

Family

ID=5876755

Family Applications (1)

Application Number Title Priority Date Filing Date
CA196,643A Expired CA1009239A (en) 1973-04-02 1974-04-02 Process for the manufacture of 2-arylamino-2-imidazoline derivatives and their salts

Country Status (23)

Country Link
US (1) US3931216A (ja)
JP (1) JPS528833B2 (ja)
BE (1) BE813144A (ja)
BG (1) BG27898A3 (ja)
CA (1) CA1009239A (ja)
CH (1) CH583708A5 (ja)
CS (1) CS176134B2 (ja)
DD (1) DD110495A1 (ja)
DE (1) DE2316377C3 (ja)
DK (1) DK145907C (ja)
ES (1) ES424859A1 (ja)
FI (1) FI59991C (ja)
FR (1) FR2223365B1 (ja)
GB (1) GB1450250A (ja)
HU (1) HU169498B (ja)
NL (1) NL167424C (ja)
NO (1) NO741170L (ja)
PL (1) PL88699B1 (ja)
RO (1) RO63906A (ja)
SE (1) SE405970B (ja)
SU (1) SU511000A3 (ja)
YU (1) YU36931B (ja)
ZA (2) ZA741910B (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT330769B (de) * 1974-04-05 1976-07-26 Chemie Linz Ag Verfahren zur herstellung von 2-arylamino- 2-imidazolin-derivaten und ihren salzen
US4125620A (en) * 1974-10-01 1978-11-14 Boehringer Ingelheim Gmbh 2-[(2',6'-Disubstituted-phenyl)-imino]-imidazolidines and salts thereof
DE2652004C3 (de) * 1976-11-15 1979-09-13 Basf Ag, 6700 Ludwigshafen l-Acyl-2-arylamino-2-imidazoline, Verfahren zu ihrer Herstellung und ihre Verwendung
NL7711390A (nl) * 1977-10-18 1979-04-20 Philips Nv Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen.
DE2811847A1 (de) * 1978-03-17 1979-09-20 Lentia Gmbh Neue arylaminoimidazolinderivate, deren herstellung und verwendung als arzneimittel
US4515800A (en) * 1981-11-20 1985-05-07 Icilio Cavero Method of lowering intraocular pressure using phenylimino-imidazoles
US4461904A (en) * 1981-11-20 1984-07-24 Alcon Laboratories, Inc. 2-(Trisubstituted phenylimino)-imidazolines
US4517199A (en) * 1981-11-20 1985-05-14 Alcon Laboratories, Inc. Method for lowering intraocular pressure using phenylimino-imidazoles
US4644007A (en) * 1981-11-20 1987-02-17 Alcon Laboratories, Inc. 3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods
HU192986B (en) 1984-05-23 1987-08-28 Egyt Gyogyszervegyeszeti Gyar Process for production of imidasodiline derivatives
DE19514579A1 (de) 1995-04-20 1996-10-24 Boehringer Ingelheim Kg Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz
US6184242B1 (en) 1997-09-04 2001-02-06 Syntex Usa (Llc) 2-(substituted-phenyl)amino-imidazoline derivatives
US6417186B1 (en) 2000-11-14 2002-07-09 Syntex (U.S.A.) Llc Substituted-phenyl ketone derivatives as IP antagonists
AU2016245434B2 (en) 2015-04-07 2020-10-29 Ela Pharma Ltd Compositions for treating and/or preventing cell or tissue necrosis specifically targeting Cathepsin C and/or CELA1 and/or CELA3A and/or structurally related enzymes thereto
RU2652125C1 (ru) * 2017-10-02 2018-04-25 Акционерное общество "Федеральный научно-производственный центр "Алтай" Способ получения 2-(2,6-дихлорфениламино)-2-имидазолина гидрохлорида

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2899426A (en) * 1959-08-11 Synthesis of l
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
DE1545628A1 (de) * 1965-10-01 1970-06-25 Boehringer Sohn Ingelheim Verfahren zur Herstellung von blutdrucksenkend und sedativ wirksamen Derivaten des 2-(2-Halogenanilino)-1,3-diazacyclopentens-(2)
US3595961A (en) * 1965-10-01 1971-07-27 Boehringer Sohn Ingelheim Hypotensive compositions containing 2-(2' - halo-anilino) - 1,3 -diazacyclopentenes-(2) and methods of using the same
BE759048A (fr) * 1969-11-17 1971-05-17 Boehringer Sohn Ingelheim Nouvelles n-aminoalcoyl-arylamino-imidazolines-(2) substituees et procedes pour les fabriquer

Also Published As

Publication number Publication date
FI59991B (fi) 1981-07-31
FR2223365B1 (ja) 1978-02-10
NO135751B (ja) 1977-02-14
JPS528833B2 (ja) 1977-03-11
RO63906A (fr) 1979-02-15
SE405970B (sv) 1979-01-15
NL167424B (nl) 1981-07-16
DD110495A1 (ja) 1974-12-20
NO135751C (ja) 1977-05-25
CH583708A5 (ja) 1977-01-14
JPS49127970A (ja) 1974-12-07
SU511000A3 (ru) 1976-04-15
US3931216A (en) 1976-01-06
CS176134B2 (ja) 1977-06-30
DK145907B (da) 1983-04-11
ZA742061B (en) 1975-03-26
DK145907C (da) 1983-09-19
YU36931B (en) 1984-08-31
FI59991C (fi) 1981-11-10
AU6728674A (en) 1975-10-02
NL7404472A (ja) 1974-10-04
DE2316377B2 (de) 1978-03-09
ES424859A1 (es) 1976-06-01
BE813144A (fr) 1974-10-01
FR2223365A1 (ja) 1974-10-25
HU169498B (ja) 1976-12-28
ZA741910B (en) 1975-03-26
BG27898A3 (en) 1980-01-15
NO741170L (no) 1974-10-03
PL88699B1 (ja) 1976-09-30
YU88174A (en) 1982-06-18
NL167424C (nl) 1981-12-16
DE2316377C3 (de) 1978-11-02
GB1450250A (en) 1976-09-22
DE2316377A1 (de) 1974-10-17

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