CA1003833A - Pyridazine derivatives - Google Patents
Pyridazine derivativesInfo
- Publication number
- CA1003833A CA1003833A CA144,468A CA144468A CA1003833A CA 1003833 A CA1003833 A CA 1003833A CA 144468 A CA144468 A CA 144468A CA 1003833 A CA1003833 A CA 1003833A
- Authority
- CA
- Canada
- Prior art keywords
- pyridazine derivatives
- pyridazine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2873771 | 1971-06-18 | ||
FR7219096A FR2141697B1 (fr) | 1971-06-18 | 1972-05-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1003833A true CA1003833A (en) | 1977-01-18 |
Family
ID=26217112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA144,468A Expired CA1003833A (en) | 1971-06-18 | 1972-06-12 | Pyridazine derivatives |
Country Status (13)
Country | Link |
---|---|
US (1) | US4169158A (fr) |
JP (1) | JPS5550943B1 (fr) |
AR (1) | AR192370A1 (fr) |
AU (1) | AU472247B2 (fr) |
BE (1) | BE784727A (fr) |
CA (1) | CA1003833A (fr) |
CH (1) | CH546769A (fr) |
DE (1) | DE2229215C2 (fr) |
ES (1) | ES403998A1 (fr) |
FR (1) | FR2141697B1 (fr) |
GB (1) | GB1345880A (fr) |
NL (1) | NL177893C (fr) |
SE (1) | SE392899B (fr) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2510998B1 (fr) * | 1981-08-07 | 1986-01-10 | Sanofi Sa | Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent |
FR2510997A1 (fr) * | 1981-08-10 | 1983-02-11 | Sanofi Sa | Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant |
FR2511366A1 (fr) * | 1981-08-11 | 1983-02-18 | Sanofi Sa | Nouveaux derives de la pyridazine, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent |
FR2539741A1 (fr) * | 1983-01-21 | 1984-07-27 | Sanofi Sa | Composes a noyau heterocyclique diazote, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent |
FR2539742B1 (fr) * | 1983-01-24 | 1986-09-05 | Sanofi Sa | Derives amines de la pyridazine substitues en position 6 par un heterocycle ou un alicycle, lesdits derives etant actifs sur le systeme nerveux central |
FR2539739B1 (fr) * | 1983-01-24 | 1985-11-22 | Sanofi Sa | Nouveaux derives de la naphtyl pyridazine actifs sur le systeme nerveux central, procede de preparation de ces derives et medicaments en contenant |
FR2540115B1 (fr) * | 1983-01-28 | 1985-06-07 | Sanofi Sa | Derive de la pyridazine ayant une action psychotrope, son mode de preparation et les medicaments en contenant |
US4565814A (en) * | 1983-01-28 | 1986-01-21 | Sanofi | Pyridazine derivatives having a psychotropic action and compositions |
FR2555178B1 (fr) * | 1983-11-18 | 1986-04-18 | Sanofi Sa | Derives cyanes de la pyridazine ayant une action psychotrope, leur mode de preparation et les medicaments en contenant |
FR2625201B1 (fr) * | 1987-12-24 | 1990-06-15 | Sanofi Sa | Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant |
FR2642757B1 (fr) * | 1989-02-07 | 1991-05-24 | Sanofi Sa | Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant |
PT93060B (pt) | 1989-02-07 | 1995-12-29 | Sanofi Sa | Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem |
FR2642648B1 (fr) * | 1989-02-07 | 1991-06-21 | Sanofi Sa | Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique |
US5461053A (en) * | 1989-02-07 | 1995-10-24 | Sanofi | Pyridazine derivatives |
FR2642754B1 (fr) * | 1989-02-07 | 1991-05-24 | Sanofi Sa | Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant |
US20100210590A1 (en) * | 1995-09-27 | 2010-08-19 | Northwestern University | Compositions and treatments for seizure-related disorders |
US20030176437A1 (en) | 2001-08-31 | 2003-09-18 | D.M. Watterson | Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death |
CA2589102C (fr) | 2004-11-02 | 2013-08-13 | Northwestern University | Composes de pyridazine et methodes d'utilisation des composes pour traiter les maladies inflammatoires |
EP2592075B1 (fr) | 2004-11-02 | 2015-04-29 | Northwestern University | Composés de pyridazine pour le traitement des maladies inflammatoires |
RU2442775C2 (ru) * | 2005-07-04 | 2012-02-20 | Хай Пойнт Фармасьютикалс, ЛЛС | Антагонисты гистаминовых н3-рецепторов |
US8501739B2 (en) * | 2005-07-04 | 2013-08-06 | High Point Pharmaceuticals, Llc | Medicaments |
US20090325973A1 (en) * | 2006-04-28 | 2009-12-31 | Watterson D Martin | Formulations containing pyridazine compounds |
EP2015751A2 (fr) * | 2006-04-28 | 2009-01-21 | Northwestern University | Sels de composés de pyridazine |
EP2015750A2 (fr) | 2006-04-28 | 2009-01-21 | Northwestern University | Compositions et traitements utilisant des pyridazines et des inhibiteurs de cholinestérase |
JP2009537596A (ja) | 2006-05-23 | 2009-10-29 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 6−(4−シクロプロピルピペリジン−1−イル)−2’−メチル−[3,4’]−ビピリジン及びその医薬としての使用 |
KR20090040259A (ko) | 2006-05-29 | 2009-04-23 | 하이 포인트 파마슈티칼스, 엘엘씨 | 3-(1,3-벤조디옥솔-5-일)-6-(4-시클로프로필피페라진-1-일)-피리다진, 그것의 염과 용매화합물 및 그것의 히스타민 h3 수용체 안타고니스트로서의 용도 |
EP2014656A3 (fr) | 2007-06-11 | 2011-08-24 | High Point Pharmaceuticals, LLC | Nouveaux antagonistes d'hétéocycliques h3 |
WO2009128057A2 (fr) | 2008-04-18 | 2009-10-22 | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN et al | Produits psycho-pharmaceutiques |
EP2560488B1 (fr) | 2010-04-23 | 2015-10-28 | Cytokinetics, Inc. | Aminopyridines et aminotriazines, leurs compositions et leurs procédés d'utilisation |
AR081331A1 (es) | 2010-04-23 | 2012-08-08 | Cytokinetics Inc | Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos |
AR081626A1 (es) * | 2010-04-23 | 2012-10-10 | Cytokinetics Inc | Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos |
CN112041679A (zh) | 2018-01-23 | 2020-12-04 | 古斯塔夫·鲁西研究所 | 米那普利用于降低肿瘤生长的用途 |
-
1971
- 1971-06-18 GB GB2873771A patent/GB1345880A/en not_active Expired
-
1972
- 1972-05-29 FR FR7219096A patent/FR2141697B1/fr not_active Expired
- 1972-06-12 BE BE784727A patent/BE784727A/fr not_active IP Right Cessation
- 1972-06-12 CA CA144,468A patent/CA1003833A/en not_active Expired
- 1972-06-15 DE DE2229215A patent/DE2229215C2/de not_active Expired
- 1972-06-16 CH CH903672A patent/CH546769A/fr not_active IP Right Cessation
- 1972-06-16 SE SE7207999A patent/SE392899B/xx unknown
- 1972-06-16 AU AU43500/72A patent/AU472247B2/en not_active Expired
- 1972-06-17 ES ES403998A patent/ES403998A1/es not_active Expired
- 1972-06-19 JP JP6054172A patent/JPS5550943B1/ja active Pending
- 1972-06-19 AR AR242634A patent/AR192370A1/es active
- 1972-06-19 NL NLAANVRAGE7208355,A patent/NL177893C/xx not_active IP Right Cessation
-
1977
- 1977-07-29 US US05/820,489 patent/US4169158A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
SE392899B (sv) | 1977-04-25 |
JPS5550943B1 (fr) | 1980-12-20 |
NL177893C (nl) | 1985-12-16 |
NL177893B (nl) | 1985-07-16 |
US4169158A (en) | 1979-09-25 |
ES403998A1 (es) | 1975-06-01 |
AU472247B2 (en) | 1973-12-20 |
FR2141697A1 (fr) | 1973-01-26 |
FR2141697B1 (fr) | 1976-09-17 |
GB1345880A (en) | 1974-02-06 |
AR192370A1 (es) | 1973-02-14 |
AU4350072A (en) | 1973-12-20 |
CH546769A (fr) | 1974-03-15 |
DE2229215A1 (de) | 1973-01-25 |
NL7208355A (fr) | 1972-12-20 |
BE784727A (fr) | 1972-10-02 |
DE2229215C2 (de) | 1984-09-06 |
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