CA1001615A - Method for purification of cephalexin - Google Patents

Method for purification of cephalexin

Info

Publication number
CA1001615A
CA1001615A CA157,867A CA157867A CA1001615A CA 1001615 A CA1001615 A CA 1001615A CA 157867 A CA157867 A CA 157867A CA 1001615 A CA1001615 A CA 1001615A
Authority
CA
Canada
Prior art keywords
cephalexin
purification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA157,867A
Other languages
English (en)
Other versions
CA157867S (en
Inventor
Shoichiro Fujii
Kunio Takanohashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9797971A external-priority patent/JPS5246237B2/ja
Priority claimed from JP4067672A external-priority patent/JPS5422998B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of CA1001615A publication Critical patent/CA1001615A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/04—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/91—Xanthomonas

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cephalosporin Compounds (AREA)
CA157,867A 1971-12-04 1972-11-30 Method for purification of cephalexin Expired CA1001615A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9797971A JPS5246237B2 (enExample) 1971-12-04 1971-12-04
JP4067672A JPS5422998B2 (enExample) 1972-04-21 1972-04-21

Publications (1)

Publication Number Publication Date
CA1001615A true CA1001615A (en) 1976-12-14

Family

ID=26380174

Family Applications (1)

Application Number Title Priority Date Filing Date
CA157,867A Expired CA1001615A (en) 1971-12-04 1972-11-30 Method for purification of cephalexin

Country Status (7)

Country Link
US (1) US3883519A (enExample)
CA (1) CA1001615A (enExample)
CH (1) CH582190A5 (enExample)
DE (1) DE2259176A1 (enExample)
FR (1) FR2164270A5 (enExample)
GB (1) GB1408168A (enExample)
NL (1) NL7216399A (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003896A (en) * 1974-12-17 1977-01-18 Novo Industri A/S Method of preparing a sparingly soluble complex of cephalexin
BE1009194A3 (nl) * 1995-03-09 1996-12-03 Dsm Nv Werkwijze voor de winning van cefalexine.
BE1009263A3 (nl) * 1995-03-31 1997-01-07 Dsm Nv Werkwijze voor de winning van cefalexine.
EP0869961B1 (en) * 1995-02-02 2001-08-22 Dsm N.V. Process for the recovery of cephalexin
BE1010651A3 (nl) * 1996-09-27 1998-11-03 Dsm Nv Werkwijze voor het zuiveren van cefalexine.
NL1007827C2 (nl) * 1997-12-18 1999-06-21 Dsm Nv Complexen van beta-lactam antibiotica.
CN116969972A (zh) * 2023-06-29 2023-10-31 华南农业大学 头孢氨苄杂质c的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1265315A (enExample) * 1968-04-05 1972-03-01 Glaxo Lab Ltd
US3634416A (en) * 1969-03-21 1972-01-11 Glaxo Lab Ltd Purification of 7alpha-aminoarylacetamido delta**3-4-carboxy-cephalosporins
GB1315484A (en) * 1969-07-25 1973-05-02 Glaxo Lab Ltd Cephalosporin compounds
US3655656A (en) * 1970-06-04 1972-04-11 Lilly Co Eli Crystalline cephalexin monohydrate
US3676434A (en) * 1970-07-29 1972-07-11 Lilly Co Eli Cephalosporin salts
US3687947A (en) * 1970-10-29 1972-08-29 Lilly Co Eli Method for recovery of cephaloridine
US3692781A (en) * 1971-02-26 1972-09-19 Glaxo Lab Ltd Recovery of pure cephalexin from acidic reaction mixtures

Also Published As

Publication number Publication date
CH582190A5 (enExample) 1976-11-30
US3883519A (en) 1975-05-13
GB1408168A (en) 1975-10-01
NL7216399A (enExample) 1973-06-06
DE2259176A1 (de) 1973-06-07
FR2164270A5 (enExample) 1973-07-27

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