BRPI1013872A2 - formulações de citrato de cálcio e lactato de cálcio para alteração de propriedades biofísicas do revestimento da mucosa - Google Patents

formulações de citrato de cálcio e lactato de cálcio para alteração de propriedades biofísicas do revestimento da mucosa

Info

Publication number
BRPI1013872A2
BRPI1013872A2 BRPI1013872A BRPI1013872A BRPI1013872A2 BR PI1013872 A2 BRPI1013872 A2 BR PI1013872A2 BR PI1013872 A BRPI1013872 A BR PI1013872A BR PI1013872 A BRPI1013872 A BR PI1013872A BR PI1013872 A2 BRPI1013872 A2 BR PI1013872A2
Authority
BR
Brazil
Prior art keywords
calcium
altering
biophysical properties
mucosal lining
lactate formulations
Prior art date
Application number
BRPI1013872A
Other languages
English (en)
Inventor
L Hava David
C Sung Jean
M Lipp Michael
Batycky Richard
W Clarke Robert
Original Assignee
Pulmatrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pulmatrix Inc filed Critical Pulmatrix Inc
Publication of BRPI1013872A2 publication Critical patent/BRPI1013872A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/04Nitro compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI1013872A 2009-03-26 2010-03-26 formulações de citrato de cálcio e lactato de cálcio para alteração de propriedades biofísicas do revestimento da mucosa BRPI1013872A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16377209P 2009-03-26 2009-03-26
US26774709P 2009-12-08 2009-12-08
PCT/US2010/028914 WO2010111650A2 (en) 2009-03-26 2010-03-26 Calcium citrate and calcium lactate formulations for alteration of biophysical properties of mucosal lining

Publications (1)

Publication Number Publication Date
BRPI1013872A2 true BRPI1013872A2 (pt) 2018-06-19

Family

ID=42635141

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1013872A BRPI1013872A2 (pt) 2009-03-26 2010-03-26 formulações de citrato de cálcio e lactato de cálcio para alteração de propriedades biofísicas do revestimento da mucosa

Country Status (11)

Country Link
US (1) US20120083531A1 (pt)
EP (1) EP2410986A2 (pt)
JP (1) JP2012522012A (pt)
KR (1) KR20120015295A (pt)
CN (1) CN102448439A (pt)
AU (1) AU2010229730A1 (pt)
BR (1) BRPI1013872A2 (pt)
CA (1) CA2754684A1 (pt)
IL (1) IL214921A0 (pt)
MX (1) MX2011009956A (pt)
WO (1) WO2010111650A2 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2410981B2 (en) 2009-03-26 2020-02-26 Pulmatrix Operating Company, Inc. Dry powder formulations and methods for treating pulmonary diseases
RU2011137961A (ru) * 2009-03-26 2013-05-10 Пулмэтрикс, Инк. Фармацевтические составы и способы лечения инфекций дыхательных путей
GB0918450D0 (en) * 2009-10-21 2009-12-09 Innovata Ltd Composition
CN105640925B (zh) * 2010-08-30 2019-08-16 普马特里克斯营业公司 干燥粉末配方及用于治疗肺部疾病的方法
US8758824B2 (en) 2010-08-30 2014-06-24 Pulmatrix, Inc. Respirably dry powder comprising calcium lactate, sodium chloride and leucine
KR101915241B1 (ko) 2010-09-29 2018-11-06 풀매트릭스 오퍼레이팅 컴퍼니, 인크 흡입용의 1가 금속 양이온 건조 분말
ES2899621T3 (es) * 2010-09-29 2022-03-14 Pulmatrix Operating Co Inc Polvos secos catiónicos que comprenden sal de magnesio
US20140336159A1 (en) 2011-10-07 2014-11-13 Pulmatrix, Inc. Methods for treating and diagnosing respiratory tract infections
PT106094A (pt) * 2012-01-13 2013-07-15 Hovione Farmaciencia S A Administração por inalação de formulações com dose elevada
CA2865972C (en) 2012-02-29 2022-01-04 Pulmatrix, Inc. Inhalable dry powders
CA2907566C (en) 2013-04-01 2023-08-22 Pulmatrix, Inc. Tiotropium dry powders
EP3052092A2 (en) * 2013-10-02 2016-08-10 Vectura Limited Method and apparatus
RU2628800C2 (ru) * 2014-03-12 2017-08-22 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Амидные соединения, способы получения, применение в качестве средств для лечения и профилактики заболеваний, вызываемых рнк-содержащими вирусами
CN107106641B (zh) 2014-10-31 2021-12-21 葛兰素史密斯克莱知识产权发展有限公司 粉末制剂
WO2016109541A1 (en) * 2014-12-29 2016-07-07 Academia Sinica Method for treating influenza a virus infection
KR101683635B1 (ko) * 2014-12-29 2016-12-09 가천대학교 산학협력단 락테이트 금속염을 포함하는 암 치료용 약학 조성물
CA2983427C (en) * 2015-05-01 2024-04-23 Board Of Regents, The University Of Texas System Multidrug brittle matrix compositions
US10046007B2 (en) 2015-06-24 2018-08-14 Prescient Pharma, Llc Compositions and methods for treatment of short telomere disorders
KR20180062063A (ko) * 2016-11-30 2018-06-08 (주) 메티메디제약 서방형 항암용 약학 조성물
CN107648207A (zh) * 2017-10-11 2018-02-02 北京北朋科技有限公司 雾化吸入用柠檬酸盐糖醇溶液
US10751365B2 (en) 2018-01-12 2020-08-25 Metimedi Pharmaceuticals Co., Ltd. Methods of treating chronic inflammatory diseases
CN110527628B (zh) * 2019-07-30 2022-05-10 南京农业大学 一种啶虫脒降解菌的保护剂及其制备方法和应用
IT202000005026A1 (it) * 2020-03-09 2021-09-09 Sofar Spa Lattoferrina per uso inalatorio ad azione antivirale

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3414539B2 (ja) * 1994-05-11 2003-06-09 有限会社ドット 経鼻吸収用組成物
US6586006B2 (en) * 1994-08-04 2003-07-01 Elan Drug Delivery Limited Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
US5612053A (en) * 1995-04-07 1997-03-18 Edward Mendell Co., Inc. Controlled release insufflation carrier for medicaments
KR20040058324A (ko) * 2001-11-26 2004-07-03 다이이찌 산토리 파마 가부시키가이샤 경비흡수용 의약 조성물
GB0207906D0 (en) * 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and mometasone aerosol formulations
CA2523740C (en) * 2003-05-01 2012-05-15 Innogene Kalbiotech Pte Ltd Lactate containing pharmaceutical composition and uses thereof
US20050207983A1 (en) * 2004-03-05 2005-09-22 Pulmatrix, Inc. Formulations decreasing particle exhalation
KR20070054644A (ko) * 2004-07-26 2007-05-29 액테리온 파마슈티칼 리미티드 미립자 제형으로 흡입된 일로프로스트에 의한 폐고혈압의치료
WO2006125153A2 (en) * 2005-05-18 2006-11-23 Pulmatrix Inc. Formulations for alteration of biophysical properties of mucosal lining
RU2011137961A (ru) * 2009-03-26 2013-05-10 Пулмэтрикс, Инк. Фармацевтические составы и способы лечения инфекций дыхательных путей
WO2010111640A2 (en) * 2009-03-26 2010-09-30 Pulmatrix, Inc. Anti-influenza formulations and methods

Also Published As

Publication number Publication date
KR20120015295A (ko) 2012-02-21
CA2754684A1 (en) 2010-09-30
JP2012522012A (ja) 2012-09-20
MX2011009956A (es) 2012-01-27
IL214921A0 (en) 2011-11-30
AU2010229730A1 (en) 2011-10-06
US20120083531A1 (en) 2012-04-05
WO2010111650A3 (en) 2010-11-18
EP2410986A2 (en) 2012-02-01
WO2010111650A2 (en) 2010-09-30
CN102448439A (zh) 2012-05-09

Similar Documents

Publication Publication Date Title
BRPI1013872A2 (pt) formulações de citrato de cálcio e lactato de cálcio para alteração de propriedades biofísicas do revestimento da mucosa
BRPI1009920A2 (pt) composições bacterianas para profilaxina e tratamento de doença degenerativa.
BRPI1012116A2 (pt) composição farmacêutica para o tratamento de doenças cardíacas
BRPI1015336A2 (pt) composições para tratamento de tecidos que compreendem polímeros de organossiloxano
BRPI0919466A2 (pt) composição farmacêutica para liberação modificada
BR112012004395A2 (pt) liberação de sdf-1 para tratamento do tecido isquêmico
BRPI0914713A2 (pt) composição para cuidado oral
DE102009028627A8 (de) Außensohle und Sportschuh
BRPI0813725A2 (pt) Métodos e composições para tratamento de doenças
GB0807224D0 (en) Remineralisation of calcified tissue
BRPI1008598A2 (pt) composição farmacêutica para inalação
BR112013016207A2 (pt) composições para cuidados orais
BRPI1006821A2 (pt) composições para o tratamento da doença de refluxo gastro-esofágico (gerd).
BRPI0918876A2 (pt) composições para a profilaxia e tratamento de doença dermatológica/mucosa, e suas utilizações
BRPI0914300A2 (pt) composições e métodos para imunogenicidade intensificada de somatostatina
BRPI1006229A2 (pt) composição incluindo uma quantidade suficiente de curcumina
BR112012010201A2 (pt) formulação de libertação modificada da lacosamida
BRPI1007600A2 (pt) composições e métodos para tratamento de doenças cardiovasculares
BRPI1005919A2 (pt) composição imunogênica
IL211073A (en) Surgical Endoscope
BRPI1007484A2 (pt) composição farmacêutica para administração oral
AU326726S (en) Toe stretcher
ZA201104670B (en) Pharmaceutical composition comprising aleglitazar
ZA201004333B (en) Treatment of oral pharyngeal dysphagia
BR112013003275A2 (pt) composição de tratamento oral

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2477 DE 26-06-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.