BRPI1012367A2 - processo para a preparação de derivados aromáticos carboxílicos triiodados - Google Patents
processo para a preparação de derivados aromáticos carboxílicos triiodadosInfo
- Publication number
- BRPI1012367A2 BRPI1012367A2 BRPI1012367A BRPI1012367A BRPI1012367A2 BR PI1012367 A2 BRPI1012367 A2 BR PI1012367A2 BR PI1012367 A BRPI1012367 A BR PI1012367A BR PI1012367 A BRPI1012367 A BR PI1012367A BR PI1012367 A2 BRPI1012367 A2 BR PI1012367A2
- Authority
- BR
- Brazil
- Prior art keywords
- triiodide
- preparation
- aromatic derivatives
- carboxylic aromatic
- carboxylic
- Prior art date
Links
- 125000003118 aryl group Chemical group 0.000 title 1
- WRTMQOHKMFDUKX-UHFFFAOYSA-N triiodide Chemical compound I[I-]I WRTMQOHKMFDUKX-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/68—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09155695A EP2230227A1 (en) | 2009-03-20 | 2009-03-20 | Process for the preparation of triiodinated carboxylic aromatic derivatives |
| PCT/EP2010/053186 WO2010105983A1 (en) | 2009-03-20 | 2010-03-12 | Process for the preparation of triiodinated carboxylic aromatic derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI1012367A2 true BRPI1012367A2 (pt) | 2016-03-29 |
| BRPI1012367B1 BRPI1012367B1 (pt) | 2020-04-07 |
| BRPI1012367B8 BRPI1012367B8 (pt) | 2021-05-25 |
Family
ID=40933154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1012367A BRPI1012367B8 (pt) | 2009-03-20 | 2010-03-12 | processo para a preparação de derivados aromáticos carboxílicos triiodados |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9096495B2 (pt) |
| EP (2) | EP2230227A1 (pt) |
| JP (1) | JP5559302B2 (pt) |
| KR (1) | KR101306033B1 (pt) |
| CN (1) | CN102325748B (pt) |
| AU (1) | AU2010224945B2 (pt) |
| BR (1) | BRPI1012367B8 (pt) |
| CA (1) | CA2755650C (pt) |
| ES (1) | ES2426610T3 (pt) |
| IL (1) | IL215209A (pt) |
| MX (1) | MX2011009057A (pt) |
| RU (1) | RU2512358C2 (pt) |
| WO (1) | WO2010105983A1 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2496971A (en) * | 2011-11-25 | 2013-05-29 | Ge Healthcare As | Preparation of X-ray contrast agents |
| DK2931696T3 (en) | 2012-12-11 | 2018-12-17 | Bracco Imaging Spa | CONTINUOUS PROCEDURE FOR THE PREPARATION OF (S) -2-ACETYLOXYPROPIONIC ACID |
| KR102358241B1 (ko) | 2014-06-10 | 2022-02-04 | 브라코 이미징 에스.피.에이. | (s)-2-아세틸옥시프로피온산 및 그것의 유도체의 제조 방법 |
| EP3548461B1 (en) * | 2016-12-05 | 2021-02-03 | Bracco Imaging SpA | Mechanochemical synthesis of radiographic agents intermediates |
| FR3062850B1 (fr) * | 2017-02-10 | 2020-01-31 | Guerbet | Procede de preparation monotope de composes organo-iodes |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1085648B (de) * | 1958-08-06 | 1960-07-21 | Lentia Gmbh | Roentgenkontrastmittel |
| CH608189A5 (pt) * | 1974-12-13 | 1978-12-29 | Savac Ag | |
| US5698739A (en) | 1989-07-05 | 1997-12-16 | Schering Aktiengesellschaft | Carboxamide non-ionic contrast media |
| IL94718A (en) * | 1989-07-05 | 1994-10-21 | Schering Ag | Non-ionic carboxamide contrast agent and method of preparation |
| IT1256162B (it) | 1992-10-27 | 1995-11-29 | Zambon Spa | Processo per la preparazione di un intermedio della sintesi organica |
| IT1256248B (it) | 1992-12-24 | 1995-11-29 | Bracco Spa | Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x |
| US5763650A (en) | 1995-05-23 | 1998-06-09 | Fructamine S.P.A. | Process for the preparation of a halosubstituted aromatic acid |
| ATE189674T1 (de) | 1995-05-23 | 2000-02-15 | Fructamine Spa | Verfahren zur herstellung von dicarbonsäure- dichlorid |
| US5616795A (en) | 1995-05-23 | 1997-04-01 | Fructamine S.P.A. | Process for the preparation of a dicarboxylic acid dichloride |
| IT1288114B1 (it) | 1996-06-13 | 1998-09-10 | Fructamine Spa | Processo per la purificazione di un intermedio |
| IT1286522B1 (it) | 1996-12-04 | 1998-07-15 | Dibra Spa | Processo per la preparazione di derivati dell'acido 5-ammino-2,4,6- triiodo-1,3-benzenedicarbossilico |
| IT1289520B1 (it) | 1996-12-24 | 1998-10-15 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati |
| IT1299202B1 (it) | 1998-05-08 | 2000-02-29 | Dibra Spa | Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo |
| IT1319671B1 (it) | 2000-12-01 | 2003-10-23 | Bracco Spa | Processo per la preparazione di (s)-n,n'-bis(2-idrossi-1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino) |
| US20100113504A1 (en) * | 2007-03-13 | 2010-05-06 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Amide compounds and their use as antitumor agents |
-
2009
- 2009-03-20 EP EP09155695A patent/EP2230227A1/en not_active Withdrawn
-
2010
- 2010-03-12 MX MX2011009057A patent/MX2011009057A/es active IP Right Grant
- 2010-03-12 CN CN201080008147.5A patent/CN102325748B/zh not_active Expired - Fee Related
- 2010-03-12 KR KR1020117020473A patent/KR101306033B1/ko active IP Right Grant
- 2010-03-12 AU AU2010224945A patent/AU2010224945B2/en not_active Ceased
- 2010-03-12 US US13/143,225 patent/US9096495B2/en not_active Expired - Fee Related
- 2010-03-12 JP JP2012500197A patent/JP5559302B2/ja not_active Expired - Fee Related
- 2010-03-12 CA CA2755650A patent/CA2755650C/en active Active
- 2010-03-12 WO PCT/EP2010/053186 patent/WO2010105983A1/en active Application Filing
- 2010-03-12 ES ES10708209T patent/ES2426610T3/es active Active
- 2010-03-12 RU RU2011142308/04A patent/RU2512358C2/ru active
- 2010-03-12 BR BRPI1012367A patent/BRPI1012367B8/pt not_active IP Right Cessation
- 2010-03-12 EP EP10708209.1A patent/EP2408735B1/en not_active Not-in-force
-
2011
- 2011-09-18 IL IL215209A patent/IL215209A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| JP5559302B2 (ja) | 2014-07-23 |
| KR20110121620A (ko) | 2011-11-07 |
| MX2011009057A (es) | 2011-09-21 |
| WO2010105983A1 (en) | 2010-09-23 |
| US20110275850A1 (en) | 2011-11-10 |
| CN102325748A (zh) | 2012-01-18 |
| KR101306033B1 (ko) | 2013-09-12 |
| CN102325748B (zh) | 2015-05-20 |
| BRPI1012367B1 (pt) | 2020-04-07 |
| JP2012520844A (ja) | 2012-09-10 |
| RU2011142308A (ru) | 2013-04-27 |
| AU2010224945B2 (en) | 2014-07-03 |
| EP2408735A1 (en) | 2012-01-25 |
| US9096495B2 (en) | 2015-08-04 |
| EP2408735B1 (en) | 2013-06-05 |
| RU2512358C2 (ru) | 2014-04-10 |
| AU2010224945A1 (en) | 2011-09-01 |
| EP2230227A1 (en) | 2010-09-22 |
| BRPI1012367B8 (pt) | 2021-05-25 |
| ES2426610T3 (es) | 2013-10-24 |
| CA2755650A1 (en) | 2010-09-23 |
| CA2755650C (en) | 2013-12-03 |
| IL215209A (en) | 2016-03-31 |
| IL215209A0 (en) | 2011-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 07/04/2020, OBSERVADAS AS CONDICOES LEGAIS. |
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| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 12/03/2010 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
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| B22B | Petition not considered [chapter 22.2 patent gazette] |
Free format text: NAO CONHECIDA A PETICAO NO 870210067455, DE 26/07/2021, EM VIRTUDE DO DISPOSTO NO ART. 219 , INCISO II DA LPI |
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| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
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| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2765 DE 02-01-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |