BRPI1011776A2 - tratamento de distúrbio pervasivos do desenvolvimento com tocotrienóis ou extratos enriquecidos com trienóis - Google Patents

tratamento de distúrbio pervasivos do desenvolvimento com tocotrienóis ou extratos enriquecidos com trienóis

Info

Publication number
BRPI1011776A2
BRPI1011776A2 BRPI1011776A BRPI1011776A BRPI1011776A2 BR PI1011776 A2 BRPI1011776 A2 BR PI1011776A2 BR PI1011776 A BRPI1011776 A BR PI1011776A BR PI1011776 A BRPI1011776 A BR PI1011776A BR PI1011776 A2 BRPI1011776 A2 BR PI1011776A2
Authority
BR
Brazil
Prior art keywords
trienol
tocotrienols
treatment
developmental disorder
pervasive developmental
Prior art date
Application number
BRPI1011776A
Other languages
English (en)
Portuguese (pt)
Inventor
M Miller Guy
Original Assignee
Ampere Life Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ampere Life Sciences Inc filed Critical Ampere Life Sciences Inc
Publication of BRPI1011776A2 publication Critical patent/BRPI1011776A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
BRPI1011776A 2009-06-25 2010-02-25 tratamento de distúrbio pervasivos do desenvolvimento com tocotrienóis ou extratos enriquecidos com trienóis BRPI1011776A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26962709P 2009-06-25 2009-06-25
PCT/US2010/025447 WO2010151348A1 (en) 2009-06-25 2010-02-25 Treatment of pervasive developmental disorders with tocotrienols or tocotrienol enriched extracts

Publications (1)

Publication Number Publication Date
BRPI1011776A2 true BRPI1011776A2 (pt) 2018-03-13

Family

ID=43386829

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1011776A BRPI1011776A2 (pt) 2009-06-25 2010-02-25 tratamento de distúrbio pervasivos do desenvolvimento com tocotrienóis ou extratos enriquecidos com trienóis

Country Status (8)

Country Link
US (1) US20120122969A1 (cg-RX-API-DMAC7.html)
EP (2) EP2445519A4 (cg-RX-API-DMAC7.html)
JP (1) JP2012531411A (cg-RX-API-DMAC7.html)
BR (1) BRPI1011776A2 (cg-RX-API-DMAC7.html)
CA (1) CA2765771A1 (cg-RX-API-DMAC7.html)
EA (1) EA201200054A1 (cg-RX-API-DMAC7.html)
MX (1) MX2011013558A (cg-RX-API-DMAC7.html)
WO (1) WO2010151348A1 (cg-RX-API-DMAC7.html)

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HUE028502T2 (en) 2007-11-06 2016-12-28 Edison Pharmaceuticals Inc 4- (P-Quinonyl) -2-hydroxybutanamide derivatives for the treatment of mitochondrial diseases
EP2237664A4 (en) * 2008-01-08 2013-05-22 Edison Pharmaceuticals Inc (HET) ARYL-p-CHINONE DERIVATIVES FOR THE TREATMENT OF OCHONDRIAL DISEASES
US8716527B2 (en) 2008-03-05 2014-05-06 Edison Pharmaceuticals, Inc. 2-substituted-p-quinone derivatives for treatment of oxidative stress diseases
US8716486B2 (en) * 2008-06-25 2014-05-06 Edison Pharmaceuticals, Inc. 2-heterocyclylaminoalkyl-(p-quinone) derivatives for treatment of oxidative stress diseases
LT3827815T (lt) 2008-09-10 2023-10-10 Ptc Therapeutics, Inc. Psichologinių raidos sutrikimų gydymas oksidacijos redukcijos atžvilgiu aktyviais vaistais
US10039722B2 (en) 2008-10-14 2018-08-07 Bioelectron Technology Corporation Treatment of oxidative stress disorders including contrast nephropathy, radiation damage and disruptions in the function of red cells
ES2553557T3 (es) 2008-10-28 2015-12-10 Edison Pharmaceuticals, Inc. Proceso para la producción de alfa-tocotrienol y derivados
HUE037574T2 (hu) 2009-04-28 2018-09-28 Bioelectron Tech Corp Leber-féle örökletes optikus neuropátia és domináns optikus atrofia kezelése tokotrienol kinonokkal
US20110207828A1 (en) * 2009-08-26 2011-08-25 Miller Guy M Methods for the prevention and treatment of cerebral ischemia
WO2013013078A1 (en) 2011-07-19 2013-01-24 Edison Pharmeceuticals, Inc. Methods for selective oxidation of alpha tocotrienol in the presence of non-alpha tocotrienols
JP6460998B2 (ja) * 2012-11-13 2019-01-30 インビクタス バイオテクノロジー プロプライエタリー リミテッド トコトリエノールの経粘膜送達
US9670170B2 (en) 2013-03-15 2017-06-06 Bioelectron Technology Corporation Resorufin derivatives for treatment of oxidative stress disorders
US9868711B2 (en) 2013-03-15 2018-01-16 Bioelectron Technology Corporation Phenazine-3-one and phenothiazine-3-one derivatives for treatment of oxidative stress disorders
US9296712B2 (en) 2013-03-15 2016-03-29 Edison Pharmaceuticals, Inc. Resorufin derivatives for treatment of oxidative stress disorders
WO2015013285A2 (en) * 2013-07-22 2015-01-29 Ohio State Innovation Foundation Methods for reducing the occurrence of hot flashes
NZ733528A (en) 2014-12-16 2021-07-30 Ptc Therapeutics Inc Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide
JP7117241B2 (ja) 2015-12-16 2022-08-12 ピーティーシー セラピューティクス, インコーポレイテッド 混合されたトコール組成物からアルファ-トコトリエノールを富化するための改良された方法
CA3008849A1 (en) 2015-12-17 2017-06-22 Bioelectron Technology Corporation Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
JP2018083799A (ja) 2016-11-15 2018-05-31 バイオエレクトロン テクノロジー コーポレイション 2−置換アミノ−ナフト[1,2−d]イミダゾール−5−オン化合物またはその製薬学上許容される塩
HUE066196T2 (hu) 2018-10-17 2024-07-28 Ptc Therapeutics Inc 2,3,5-trimetil-6-nonilciklohexa-2,5-dién-1,4-dion alfa-szinukleinopátiák, tauopátiák és egyéb rendellenességek szuppresszálására és kezelésére
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
US20220214358A1 (en) * 2019-04-05 2022-07-07 Arizona Board Of Regents On Behalf Of Arizona State University Diagnostic for childhood risk of autism spectrum disorder
MY196888A (en) * 2019-11-19 2023-05-08 Hovid Berhad A composition for managing cadasil
EP3981397A1 (en) * 2020-10-08 2022-04-13 Global Scientific Tocotrienols derivates, methods and uses thereof
CA3225266A1 (en) 2021-07-08 2023-01-12 Swathi PINNAMANENI Pharmaceutical compositions comprising 2,3,5-trimethyl-6-nonylcyclohexa-2,5-diene-1,4-dione

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JP2685785B2 (ja) 1988-03-11 1997-12-03 エーザイ株式会社 光学活性α−トコトリエノールの製造方法
JPH029875A (ja) 1988-03-16 1990-01-12 Bio Ind Kyokai トコフェロール及びトコトリエノールの製造方法
US5157132A (en) 1990-05-18 1992-10-20 Carotech Associates Integrated process for recovery of carotenoids and tocotrienols from oil
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US6838104B2 (en) 2000-12-20 2005-01-04 Archer Daniels Midland Company Process for the production of tocotrienols
US7217133B2 (en) * 2002-04-04 2007-05-15 Jeanine Thomas Method for treating pervasive development disorder
AT414082B (de) * 2002-05-03 2006-09-15 Vis Vitalis Lizenz & Handels Verfahren zur herstellung von tocotrienol-angereicherten präparationen
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MXPA06009529A (es) 2004-02-23 2007-04-10 Texas A & M Univ Sys Composiciones antioxidantes y metodos para el uso de las mismas.
US10300034B2 (en) * 2007-02-22 2019-05-28 Children's Hospital Of Oakland Research Institute Fatty acid formulations and methods of use thereof
KR101481197B1 (ko) 2007-05-24 2015-01-09 로더스 크로클란 비.브이. 토코페롤 및 토코트리에놀을 함유하는 조성물의 제조방법

Also Published As

Publication number Publication date
EA201200054A1 (ru) 2012-05-30
CA2765771A1 (en) 2010-12-29
EP2445519A4 (en) 2012-12-26
MX2011013558A (es) 2012-04-30
WO2010151348A1 (en) 2010-12-29
EP2609921A1 (en) 2013-07-03
JP2012531411A (ja) 2012-12-10
EP2445519A1 (en) 2012-05-02
US20120122969A1 (en) 2012-05-17

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]