BRPI0922944A2 - Célula hospedeira projetada metabolicamente para a produção de um alcano, contendo uma ou mais sequências de ácido nucleico exógeno e método para produzir um alcano - Google Patents

Célula hospedeira projetada metabolicamente para a produção de um alcano, contendo uma ou mais sequências de ácido nucleico exógeno e método para produzir um alcano

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Publication number
BRPI0922944A2
BRPI0922944A2 BRPI0922944-2A BRPI0922944A BRPI0922944A2 BR PI0922944 A2 BRPI0922944 A2 BR PI0922944A2 BR PI0922944 A BRPI0922944 A BR PI0922944A BR PI0922944 A2 BRPI0922944 A2 BR PI0922944A2
Authority
BR
Brazil
Prior art keywords
alkane
producing
nucleic acid
production
host cell
Prior art date
Application number
BRPI0922944-2A
Other languages
English (en)
Portuguese (pt)
Inventor
Brian M Baynes
Michael John Geremia
Original Assignee
Celexion Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celexion Llc filed Critical Celexion Llc
Publication of BRPI0922944A2 publication Critical patent/BRPI0922944A2/pt

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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/001Amines; Imines
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/005Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • C12P7/46Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • C12P7/50Polycarboxylic acids having keto groups, e.g. 2-ketoglutaric acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BRPI0922944-2A 2008-12-12 2009-12-14 Célula hospedeira projetada metabolicamente para a produção de um alcano, contendo uma ou mais sequências de ácido nucleico exógeno e método para produzir um alcano BRPI0922944A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20157608P 2008-12-12 2008-12-12
PCT/US2009/067895 WO2010068944A2 (en) 2008-12-12 2009-12-14 Biological synthesis of difunctional alkanes from carbohydrate feedstocks

Publications (1)

Publication Number Publication Date
BRPI0922944A2 true BRPI0922944A2 (pt) 2015-08-25

Family

ID=41508860

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922944-2A BRPI0922944A2 (pt) 2008-12-12 2009-12-14 Célula hospedeira projetada metabolicamente para a produção de um alcano, contendo uma ou mais sequências de ácido nucleico exógeno e método para produzir um alcano

Country Status (11)

Country Link
US (6) US8192976B2 (https=)
EP (1) EP2366026A2 (https=)
JP (2) JP2012511910A (https=)
KR (1) KR20110104952A (https=)
CN (1) CN102317464B (https=)
AU (1) AU2009324422A1 (https=)
BR (1) BRPI0922944A2 (https=)
CA (1) CA2747241A1 (https=)
MY (1) MY153590A (https=)
RU (1) RU2496880C2 (https=)
WO (1) WO2010068944A2 (https=)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0806695A2 (pt) * 2007-01-12 2014-06-03 Univ Colorado Composições e métodos para aumentar a tolerância à produção de produtos químicos produzidos por microorganismos
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
US8192976B2 (en) * 2008-12-12 2012-06-05 Celexion, Llc Biological synthesis of difunctional alkanes from carbohydrate feedstocks
US8404465B2 (en) 2009-03-11 2013-03-26 Celexion, Llc Biological synthesis of 6-aminocaproic acid from carbohydrate feedstocks
WO2010104391A2 (en) * 2009-03-11 2010-09-16 Dsm Ip Assets B.V. Preparation of adipic acid
DK2427544T3 (da) 2009-05-07 2019-10-07 Genomatica Inc Mikroorganismer og fremgangsmåder til biosyntese af adipat, hexamethylendiamin og 6-aminokapronsyre
EP2449091A4 (en) 2009-07-02 2012-12-05 Verdezyne Inc BIOLOGICAL METHODS FOR PREPARING ADIPIC ACID
GB2487866A (en) 2009-09-27 2012-08-08 Opx Biotechnologies Inc Method for producing 3-Hydroxypropionic acid and other products
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
WO2011063363A2 (en) * 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an organic acid and/or related chemicals
US8911978B2 (en) * 2010-07-02 2014-12-16 Metabolic Explorer Method for the preparation of hydroxy acids
TWI500768B (zh) * 2010-07-05 2015-09-21 Metabolic Explorer Sa 由蔗糖製備1,3-丙二醇之方法
BR112013005786A2 (pt) * 2010-09-10 2018-04-24 Dsm Ip Assets Bv preparação de ácido 6-aminocapróico de ácido alfa-cetopimélico
WO2012031910A2 (en) * 2010-09-10 2012-03-15 Dsm Ip Assets B.V. Method for preparing alpha-ketopimelic acid by c1-elongation
KR101883511B1 (ko) * 2010-10-19 2018-07-30 글로벌 바이오에너지스 3-히드록시알카노산의 조합된 효소적 전환에 의한 알켄의 제조
JPWO2012137771A1 (ja) * 2011-04-08 2014-07-28 昭和電工株式会社 アジピン酸の製造方法
US8728798B2 (en) 2011-05-03 2014-05-20 Verdezyne, Inc. Biological methods for preparing adipic acid
US8343752B2 (en) 2011-05-03 2013-01-01 Verdezyne, Inc. Biological methods for preparing adipic acid
US8852899B2 (en) * 2011-06-17 2014-10-07 Invista North America S.A.R.L. Methods of making nylon intermediates from glycerol
EP2720997A1 (en) * 2011-06-17 2014-04-23 Invista Technologies S.à.r.l. Use of hydrolases to increase monomer content in waste stream
EP2726627A2 (en) * 2011-06-30 2014-05-07 Invista Technologies S.à.r.l. Bioconversion process for producing nylon-7, nylon-7,7 and polyesters
US9102960B2 (en) 2011-12-16 2015-08-11 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
US9102958B2 (en) 2011-12-16 2015-08-11 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
CN104126012A (zh) * 2011-12-21 2014-10-29 英威达技术有限责任公司 用于生产尼龙-7、尼龙-7,7和聚酯的生物转化工艺
WO2013130487A2 (en) 2012-02-29 2013-09-06 Duke University Novel oxidoreductases for enantioselective reactions
EP2647718A3 (en) * 2012-04-06 2014-12-24 Metabolic Explorer Process for producing 5-aminopentanoate empolying a recombinant microorganism
US20130288320A1 (en) 2012-04-27 2013-10-31 Bioamber Inc. Methods and microorganisms for increasing the biological synthesis of difunctional alkanes
SG11201501013PA (en) 2012-08-10 2015-04-29 Opx Biotechnologies Inc Microorganisms and methods for the production of fatty acids and fatty acid derived products
AU2012327243A1 (en) * 2012-08-17 2014-03-06 Celexion, Llc Biological synthesis of difunctional hexanes and pentanes from carbohydrate feedstocks
EP2888356A1 (en) * 2012-08-23 2015-07-01 Bioamber Inc. Methods and microorganisms for the biological synthesis of (s)-2-amino-6-hydroxypimelate, hexamethylenediamine and 6-aminocaproate
CA2880726C (en) * 2012-09-14 2020-01-21 Bioamber Inc. Alternative pathways to adipates and adipic acid by combined fermentation and catalytic methods
US9790525B2 (en) 2012-12-14 2017-10-17 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
EP2938736A2 (en) * 2012-12-31 2015-11-04 Invista Technologies S.A R.L. Methods of producing 7-carbon chemicals via c1 carbon chain elongation associated with coenzyme b synthesis
CN105408487A (zh) 2012-12-31 2016-03-16 英威达技术有限责任公司 通过甲酯保护的碳链延伸生产7碳化学物的方法
WO2014105793A1 (en) 2012-12-31 2014-07-03 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals from long chain fatty acids via oxidative cleavage
EP2938734A2 (en) 2012-12-31 2015-11-04 Invista Technologies S.A R.L. Methods of producing 7-carbon chemicals via aromatic compounds
EP2938731A2 (en) * 2012-12-31 2015-11-04 Invista Technologies S.A R.L. Methods of producing 7-carbon chemicals via carbon chain elongation associated with cyclohexane carboxylate synthesis
WO2014105797A2 (en) * 2012-12-31 2014-07-03 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via pyruvate and succinate semialdehyde aldol condensation
CN105073214A (zh) * 2012-12-31 2015-11-18 英威达技术有限责任公司 通过甲酯保护的碳链延伸生产6碳化学物的方法
CA2905602A1 (en) 2013-03-15 2014-09-18 Sarah M. Hoyt Flash evaporation for product purification and recovery
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
CN106795483A (zh) 2013-07-19 2017-05-31 嘉吉公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US10266852B2 (en) 2013-12-06 2019-04-23 Alliance For Sustainable Energy, Llc Lignin conversion to fuels, chemicals and materials
CN104725239A (zh) * 2013-12-18 2015-06-24 江南大学 一种高级脂肪胺的制备方法
US9745607B2 (en) 2014-05-15 2017-08-29 Invista North America S.A.R.L. Methods of producing 6-carbon chemicals using 2,6-diaminopimelate as precursor to 2-aminopimelate
WO2015195703A1 (en) * 2014-06-16 2015-12-23 Invista Technologies S.A R.L. Methods, reagents and cells for biosynthesizing compounds
US9988654B2 (en) 2014-06-16 2018-06-05 Invista North America S.A.R.L. Methods, reagents and cells for biosynthesizing compounds
US9957535B2 (en) 2014-06-16 2018-05-01 Invista North America S.A.R.L. Methods, reagents and cells for biosynthesizing compounds
CN106795535A (zh) * 2014-06-16 2017-05-31 英威达技术有限责任公司 用于生物合成化合物的方法,试剂和细胞
US20170152531A1 (en) 2014-06-16 2017-06-01 North America S.A.R.L. Process for producing glutarate and glutaric acid methyl ester
WO2015200287A1 (en) * 2014-06-23 2015-12-30 The Trustees Of Columbia University In The City Of New York Methods and systems for producing products using engineered iron oxidizing bacteria and copper metal
US10017792B2 (en) 2014-07-18 2018-07-10 Alliance For Sustainable Energy, Llc Biomass conversion to fuels and chemicals
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
JP7127987B2 (ja) 2014-12-23 2022-08-30 ジェノマティカ, インコーポレイテッド ジアミンの製造および処理方法
CA2897454C (en) * 2015-07-03 2023-03-14 Governing Council Of The University Of Toronto Microorganisms and methods for biosynthesis of adipic acid
EP3330380A1 (en) * 2016-12-05 2018-06-06 Evonik Degussa GmbH Process for producing l-methionine from methional
EP3577227A4 (en) 2017-02-02 2020-12-30 Cargill Inc. GENETICALLY MODIFIED CELLS PRODUCING C6-C10 FATTY ACID DERIVATIVES
US11136601B2 (en) 2018-08-02 2021-10-05 Alliance For Sustainable Energy, Llc Conversion of S-lignin compounds to useful intermediates
WO2020171867A2 (en) * 2018-11-29 2020-08-27 Zymergen, Inc. Engineered biosynthetic pathways for production of 2-oxoadipate by fermentation
KR20220023757A (ko) * 2019-04-24 2022-03-02 게노마티카 인코포레이티드 알데하이드 데하이드로게나아제 활성을 개선하기 위한 조작된 미생물 및 방법
CN117083388A (zh) * 2021-03-30 2023-11-17 旭化成株式会社 具有酰基CoA化合物还原活性的重组多肽
CN114990043B (zh) * 2022-06-28 2024-04-30 滨州医学院 代谢赖氨酸的工程菌及其构建方法与应用
KR102901474B1 (ko) * 2025-01-21 2025-12-19 한국화학연구원 알파케토글루타르산 세미알데히드 탈수소 효소 변이체 및 이를 이용한 3-하이드록시프로피온산 생산방법

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485821A (en) * 1967-05-29 1969-12-23 Techni Chem Co The Process for preparing caprolactam and its alkyl substituted derivatives
US4400468A (en) * 1981-10-05 1983-08-23 Hydrocarbon Research Inc. Process for producing adipic acid from biomass
GB2108486B (en) * 1981-10-26 1986-01-29 Farmos Group Ltd Alkane and alkene derivatives and their preparation and use
US4725542A (en) * 1983-01-13 1988-02-16 Celgene Corporation Production of nylon 6,6 salt
US4929396A (en) * 1983-01-13 1990-05-29 Celgene Corporation Production of hexamethylenediamine muconate salt
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
DE3602377A1 (de) * 1986-01-28 1987-07-30 Basf Ag Verfahren zur herstellung von caprolactam
US5221800A (en) * 1989-09-05 1993-06-22 Amoco Corporation One step air oxidation of cyclohexane to produce adipic acid
FR2669643B1 (fr) * 1990-11-28 1995-04-28 Rhone Poulenc Chimie Procede de synthese enzymatique d'adipate d'ammonium.
US5272073A (en) * 1992-06-30 1993-12-21 Purdue Research Foundation Biocatalytic synthesis of catechol from glucose
US5629190A (en) * 1992-08-10 1997-05-13 Rhone-Poulenc Chimie Polypeptides possessing a nitrilase activity and method of converting nitriles to carboxylates by means of said polypeptides
US5487987A (en) 1993-09-16 1996-01-30 Purdue Research Foundation Synthesis of adipic acid from biomass-derived carbon sources
FR2736928B1 (fr) * 1995-07-18 1997-10-17 Rhone Poulenc Fibres & Polymer Enzymes ayant une activite amidase micro-organismes susceptibles de produire de telles enzymes et procede d'hydrolyse d'amides en faisant application
US6365376B1 (en) * 1999-02-19 2002-04-02 E. I. Du Pont De Nemours And Company Genes and enzymes for the production of adipic acid intermediates
US6498242B1 (en) * 1999-02-19 2002-12-24 E. I. Du Pont De Nemours And Company Biological method for the production of adipic acid and intermediates
MXPA03009877A (es) * 2001-05-04 2005-07-15 Univ Florida Clonacion y secuenciamiento de genes de piruvato decarboxilasa (pdc) a partir de bacterias y usos de los mismos.
FR2828711B1 (fr) 2001-08-14 2004-03-12 Serge Janiszewski Moteur thermique, a combustion interne, a cycle a deux temps avec un embiellage a plateaux oscillants indexes et un compresseur rapporte indexe
DE60313866T2 (de) 2002-06-14 2008-04-17 Dsm Ip Assets B.V. Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür
US7563600B2 (en) * 2002-09-12 2009-07-21 Combimatrix Corporation Microarray synthesis and assembly of gene-length polynucleotides
BRPI0506942B1 (pt) * 2004-01-19 2015-07-28 Dsm Ip Assets B.V. Síntese bioquímica de ácido 6-amino capróico
EP1812598A1 (en) * 2004-10-18 2007-08-01 Codon Devices, Inc. Methods for assembly of high fidelity synthetic polynucleotides
JP2008526259A (ja) * 2005-01-13 2008-07-24 コドン デバイシズ インコーポレイテッド 蛋白質デザインのための組成物及び方法
WO2007136834A2 (en) * 2006-05-19 2007-11-29 Codon Devices, Inc. Combined extension and ligation for nucleic acid assembly
WO2007136840A2 (en) * 2006-05-20 2007-11-29 Codon Devices, Inc. Nucleic acid library design and assembly
US20080287320A1 (en) * 2006-10-04 2008-11-20 Codon Devices Libraries and their design and assembly
WO2008127283A2 (en) 2006-10-06 2008-10-23 Codon Devices, Inc. Engineered metabolic pathways
DE102007005072A1 (de) 2007-02-01 2008-08-07 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von Cadaverin
WO2009046370A2 (en) 2007-10-04 2009-04-09 Bio Architecture Lab, Inc. Biofuel production
US8673599B2 (en) 2008-03-11 2014-03-18 Dsm Ip Assets B.V. Preparation of 6-aminocaproic acid from 5-formylvaleric acid
US9096873B2 (en) 2008-03-11 2015-08-04 Genomatica, Inc. Adipate (ester or thioester) synthesis
CN102066551B (zh) 2008-03-27 2013-10-09 基因组股份公司 用于产生己二酸和其他化合物的微生物
US8192976B2 (en) * 2008-12-12 2012-06-05 Celexion, Llc Biological synthesis of difunctional alkanes from carbohydrate feedstocks

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US20120258504A1 (en) 2012-10-11
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AU2009324422A1 (en) 2011-07-07
WO2010068944A2 (en) 2010-06-17
EP2366026A2 (en) 2011-09-21
US8133704B2 (en) 2012-03-13
JP2015221054A (ja) 2015-12-10
JP2012511910A (ja) 2012-05-31
CN102317464A (zh) 2012-01-11
US8778642B2 (en) 2014-07-15
US20150322441A1 (en) 2015-11-12
WO2010068944A3 (en) 2010-09-23
US20110171696A1 (en) 2011-07-14
US8192976B2 (en) 2012-06-05
US9062314B2 (en) 2015-06-23
US20100151536A1 (en) 2010-06-17
US20140206069A1 (en) 2014-07-24
US20120164702A1 (en) 2012-06-28
RU2496880C2 (ru) 2013-10-27
MY153590A (en) 2015-02-26
CA2747241A1 (en) 2010-06-17

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