BRPI0922856A2 - processo para preparar (6s)-(-)-5,6,7,8-tetra-hidro-6-[propil-(2-tienil)etil] amino-1-naftol (rotigotina) - Google Patents
processo para preparar (6s)-(-)-5,6,7,8-tetra-hidro-6-[propil-(2-tienil)etil] amino-1-naftol (rotigotina)Info
- Publication number
- BRPI0922856A2 BRPI0922856A2 BRPI0922856A BRPI0922856A BRPI0922856A2 BR PI0922856 A2 BRPI0922856 A2 BR PI0922856A2 BR PI0922856 A BRPI0922856 A BR PI0922856A BR PI0922856 A BRPI0922856 A BR PI0922856A BR PI0922856 A2 BRPI0922856 A2 BR PI0922856A2
- Authority
- BR
- Brazil
- Prior art keywords
- rotigotine
- naphthol
- tetrahydro
- thienyl
- propyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200803472 | 2008-12-09 | ||
PCT/EP2009/066662 WO2010066755A1 (en) | 2008-12-09 | 2009-12-09 | Process for the preparation of (6s)-(-)-5,6,7,8-tetrahydro-6-[propyl-(2-thienyl)ethyl]amino-1-naphthol (rotigotine) |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0922856A2 true BRPI0922856A2 (pt) | 2018-01-30 |
Family
ID=41548625
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0922856A BRPI0922856A2 (pt) | 2008-12-09 | 2009-12-09 | processo para preparar (6s)-(-)-5,6,7,8-tetra-hidro-6-[propil-(2-tienil)etil] amino-1-naftol (rotigotina) |
Country Status (9)
Country | Link |
---|---|
US (1) | US8513438B2 (pt) |
EP (1) | EP2376470B1 (pt) |
JP (1) | JP5748666B2 (pt) |
KR (1) | KR101774598B1 (pt) |
BR (1) | BRPI0922856A2 (pt) |
ES (1) | ES2420118T3 (pt) |
IL (1) | IL212959A (pt) |
MX (1) | MX2011005979A (pt) |
WO (1) | WO2010066755A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2839366C (en) | 2011-06-27 | 2015-01-20 | Shan Dong Luye Pharmaceutical Co., Ltd. | Method for industrially preparing nitrogen substituted amino-5,6,7,8-tetrahydronaphthol |
JP5829741B2 (ja) * | 2013-09-05 | 2015-12-09 | 田辺三菱製薬株式会社 | 新規な結晶性アリールアルキルアミン化合物およびその製造方法 |
WO2015034031A1 (ja) * | 2013-09-05 | 2015-03-12 | 田辺三菱製薬株式会社 | 新規な結晶性アリールアルキルアミン化合物およびその製造方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4564628A (en) * | 1983-01-03 | 1986-01-14 | Nelson Research & Development Co. | Substituted 2-aminotetralins |
IT1254521B (it) | 1992-03-17 | 1995-09-25 | Zambon Spa | Derivati della 2-ammino-tetralina attivi sul sistema cardiovascolare |
DE60008136T2 (de) * | 1999-11-23 | 2004-09-09 | Aderis Pharmaceuticals, Inc. | Verbessertes verfahren zur herstellung von n-substituierte aminotetraline |
PT2457904E (pt) * | 2006-07-11 | 2015-02-27 | Wista Lab Ltd | Processos de síntese e/ou purificação de compostos diaminofenotiazínio |
JP2008115175A (ja) * | 2006-10-13 | 2008-05-22 | Otsuka Pharmaceut Co Ltd | 複素環化合物 |
-
2009
- 2009-12-09 US US13/133,898 patent/US8513438B2/en active Active
- 2009-12-09 WO PCT/EP2009/066662 patent/WO2010066755A1/en active Application Filing
- 2009-12-09 BR BRPI0922856A patent/BRPI0922856A2/pt not_active Application Discontinuation
- 2009-12-09 KR KR1020117014143A patent/KR101774598B1/ko active IP Right Grant
- 2009-12-09 MX MX2011005979A patent/MX2011005979A/es active IP Right Grant
- 2009-12-09 JP JP2011540060A patent/JP5748666B2/ja active Active
- 2009-12-09 EP EP09768378.3A patent/EP2376470B1/en active Active
- 2009-12-09 ES ES09768378T patent/ES2420118T3/es active Active
-
2011
- 2011-05-17 IL IL212959A patent/IL212959A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
MX2011005979A (es) | 2011-06-27 |
US8513438B2 (en) | 2013-08-20 |
IL212959A0 (en) | 2011-07-31 |
JP2012511538A (ja) | 2012-05-24 |
EP2376470A1 (en) | 2011-10-19 |
US20110306776A1 (en) | 2011-12-15 |
IL212959A (en) | 2016-03-31 |
KR20110098748A (ko) | 2011-09-01 |
KR101774598B1 (ko) | 2017-09-04 |
JP5748666B2 (ja) | 2015-07-15 |
ES2420118T3 (es) | 2013-08-22 |
WO2010066755A1 (en) | 2010-06-17 |
EP2376470B1 (en) | 2013-04-10 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |