BRPI0922787A2 - Formas polimórficas de um derivado da azabiciclo-trifluorometil benzamida - Google Patents

Formas polimórficas de um derivado da azabiciclo-trifluorometil benzamida

Info

Publication number
BRPI0922787A2
BRPI0922787A2 BRPI0922787A BRPI0922787A BRPI0922787A2 BR PI0922787 A2 BRPI0922787 A2 BR PI0922787A2 BR PI0922787 A BRPI0922787 A BR PI0922787A BR PI0922787 A BRPI0922787 A BR PI0922787A BR PI0922787 A2 BRPI0922787 A2 BR PI0922787A2
Authority
BR
Brazil
Prior art keywords
azabicycle
forms
benzamide derivative
polymorphic forms
trifluoromethyl benzamide
Prior art date
Application number
BRPI0922787A
Other languages
English (en)
Inventor
Zlotinikov Evgeny
Wu Xiao-Dong
lieberman Harvey
Gordonov Boris
Donegan Timothy
Shadeed Diana
Guo Yushen
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of BRPI0922787A2 publication Critical patent/BRPI0922787A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

FORMAS POLIMÓRFICAS DE UM DERIVADO DA AZABICICLO-TRIFLUOROMETIL BENZAMIDA. A presente descrição refere-se a formas sólidas do composto de acordo com a fórmula (I), às composições que compreendem essas formas, e a processos para sua preparação. A descrição também refere-se a métodos para tratamento de distúrbios neurológicos através da administração destas formas.
BRPI0922787A 2008-12-04 2009-12-03 Formas polimórficas de um derivado da azabiciclo-trifluorometil benzamida BRPI0922787A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11981108P 2008-12-04 2008-12-04
PCT/US2009/066515 WO2010065701A1 (en) 2008-12-04 2009-12-03 Novel polymorphic forms of an azabicyclo-trifluoromethyl benzamide derivative

Publications (1)

Publication Number Publication Date
BRPI0922787A2 true BRPI0922787A2 (pt) 2017-07-11

Family

ID=41789690

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922787A BRPI0922787A2 (pt) 2008-12-04 2009-12-03 Formas polimórficas de um derivado da azabiciclo-trifluorometil benzamida

Country Status (11)

Country Link
US (1) US20120022099A1 (pt)
EP (1) EP2373651A1 (pt)
JP (1) JP2012511006A (pt)
KR (1) KR20110095400A (pt)
CN (1) CN102256975A (pt)
AU (1) AU2009322420A1 (pt)
BR (1) BRPI0922787A2 (pt)
CA (1) CA2745690A1 (pt)
IL (1) IL213285A0 (pt)
MX (1) MX2011005971A (pt)
WO (1) WO2010065701A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017537681A (ja) * 2014-11-03 2017-12-21 ザ・ジョージ・ワシントン・ユニバーシティＴｈｅ Ｇｅｏｒｇｅ Ｗａｓｈｉｎｇｔｏｎｕｎｉｖｅｒｓｉｔｙ 損傷評価システム及びその方法
US20170189097A1 (en) * 2016-01-05 2017-07-06 Iowa Approach Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
JOP20210295A1 (ar) * 2019-05-01 2023-01-30 Boehringer Ingelheim Int أشكال صلبة لمثبط GlyT1

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2322136A1 (en) * 1998-03-06 1999-09-10 Ludo Edmond Josephine Kennis Glycine transport inhibitors
FR2861076B1 (fr) 2003-10-17 2006-01-06 Sanofi Synthelabo Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
JP2012511006A (ja) 2012-05-17
US20120022099A1 (en) 2012-01-26
AU2009322420A1 (en) 2011-06-23
CN102256975A (zh) 2011-11-23
IL213285A0 (en) 2011-07-31
KR20110095400A (ko) 2011-08-24
CA2745690A1 (en) 2010-06-10
WO2010065701A1 (en) 2010-06-10
MX2011005971A (es) 2011-09-01
EP2373651A1 (en) 2011-10-12

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]