BRPI0922658A2 - sistemas e métodos para obter imunoglobulina a partir de sangue - Google Patents

sistemas e métodos para obter imunoglobulina a partir de sangue

Info

Publication number
BRPI0922658A2
BRPI0922658A2 BRPI0922658A BRPI0922658A BRPI0922658A2 BR PI0922658 A2 BRPI0922658 A2 BR PI0922658A2 BR PI0922658 A BRPI0922658 A BR PI0922658A BR PI0922658 A BRPI0922658 A BR PI0922658A BR PI0922658 A2 BRPI0922658 A2 BR PI0922658A2
Authority
BR
Brazil
Prior art keywords
immunoglobulin
blood
systems
methods
Prior art date
Application number
BRPI0922658A
Other languages
English (en)
Inventor
Francisco M Rausa Iii
Kyungyoon Min
Larry Backes
Sharon Pokropinski
Shawn F Bairstow
Sindhu Ramachandran
Original Assignee
Baxter Healthcare Sa
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Healthcare Sa, Baxter Int filed Critical Baxter Healthcare Sa
Publication of BRPI0922658A2 publication Critical patent/BRPI0922658A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
    • A61M1/382—Optimisation of blood component yield
    • A61M1/385—Optimisation of blood component yield taking into account of the patient characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0213—Multiple bag systems for separating or storing blood components with isolated sections of the tube used as additive reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0259—Apparatus for treatment of blood or blood constituents not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/84—Drainage tubes; Aspiration tips
    • A61M1/85—Drainage tubes; Aspiration tips with gas or fluid supply means, e.g. for supplying rinsing fluids or anticoagulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0415—Plasma
    • A61M2202/0417—Immunoglobulin
    • A61M2202/0419—Immunoglobulin G

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Surgery (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BRPI0922658A 2008-12-19 2009-12-18 sistemas e métodos para obter imunoglobulina a partir de sangue BRPI0922658A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/339,900 US20100158893A1 (en) 2008-12-19 2008-12-19 Systems and methods for obtaining immunoglobulin from blood
PCT/US2009/068753 WO2010071809A1 (en) 2008-12-19 2009-12-18 Systems and methods for obtaining immunoglobulin from blood

Publications (1)

Publication Number Publication Date
BRPI0922658A2 true BRPI0922658A2 (pt) 2016-01-05

Family

ID=42026169

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922658A BRPI0922658A2 (pt) 2008-12-19 2009-12-18 sistemas e métodos para obter imunoglobulina a partir de sangue

Country Status (10)

Country Link
US (4) US20100158893A1 (pt)
EP (1) EP2385850B1 (pt)
JP (1) JP5689425B2 (pt)
KR (1) KR20110114555A (pt)
CN (2) CN102256641A (pt)
AU (1) AU2009327420B2 (pt)
BR (1) BRPI0922658A2 (pt)
ES (1) ES2474740T3 (pt)
MX (1) MX2011006608A (pt)
WO (1) WO2010071809A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100158893A1 (en) * 2008-12-19 2010-06-24 Baxter International Inc. Systems and methods for obtaining immunoglobulin from blood
US10413652B2 (en) 2011-04-13 2019-09-17 Fenwal, Inc. Systems and methods for use and control of an automated separator with adsorption columns
EP2995621A1 (en) 2014-09-10 2016-03-16 Previpharma AG Ligands and methods for isolating or removing proteins
EP3266145B1 (en) * 2015-03-05 2019-07-31 Telefonaktiebolaget LM Ericsson (publ) Full-duplex power reporting

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409330A (en) * 1980-11-24 1983-10-11 American Hoechst Corporation Material and method for removing immunoglobulins from whole blood
US4464165A (en) * 1980-11-24 1984-08-07 American Hoechst Corporation Material and method for removing immunoglobulins from whole blood
US4639513A (en) * 1984-02-02 1987-01-27 Cuno Inc. Intravenously injectable immunoglobulin G (IGG) and method for producing same
US4714680B1 (en) * 1984-02-06 1995-06-27 Univ Johns Hopkins Human stem cells
US4704366A (en) * 1984-06-22 1987-11-03 Bio-Rad Laboratories, Inc. Process for binding IgG to protein A
US4678566A (en) * 1984-07-20 1987-07-07 Terumo Kabushiki Kaisha Apparatus for separating proteins from blood plasma
US4614513A (en) * 1984-08-13 1986-09-30 Fred Hutchinson Cancer Research Center Method and apparatus for treatment to remove immunoreactive substances from blood
US4776964A (en) * 1984-08-24 1988-10-11 William F. McLaughlin Closed hemapheresis system and method
DE3664729D1 (en) * 1985-04-09 1989-09-07 Terumo Corp Immunoglobulin adsorbent and adsorption apparatus
SE8601891D0 (sv) * 1986-04-24 1986-04-24 Svante Jonsson Maskin for plasmabytesbehandling och trombocytgivning
EP0269279A3 (en) * 1986-11-21 1988-09-14 Imre Corporation Extracorporeal removal of immunoglobulin-g and circulating immune complexes
US5782792A (en) * 1986-11-21 1998-07-21 Cypress Bioscience, Inc. Method for treatment of rheumatoid arthritis
JPS63132665A (ja) * 1986-11-26 1988-06-04 テルモ株式会社 血液中蛋白質の回収装置
DE3723092C1 (de) * 1987-07-13 1989-01-26 Westfalia Separator Ag Durchlaufzentrifuge zur industriellen Produktion von Proteinen aus menschlichem Blutplasma
US5733254A (en) * 1987-10-15 1998-03-31 Cypress Bioscience, Inc. Method for treating patients suffering from immune thrombocytopenic purpura
US5084398A (en) * 1987-11-20 1992-01-28 Creative Biomolecules Selective removal of immune complexes
US5243040A (en) * 1987-11-20 1993-09-07 Creative Biomolecules DNA encoding a protein which enables selective removal of immune complexes
US5427695A (en) * 1993-07-26 1995-06-27 Baxter International Inc. Systems and methods for on line collecting and resuspending cellular-rich blood products like platelet concentrate
US5593822A (en) * 1993-12-07 1997-01-14 John Wayne Cancer Institute IgG depleted serum preparations and methods for antibody production
DE4344824C1 (de) * 1993-12-28 1995-08-31 Immuno Ag Hochkonzentriertes Immunglobulin-Präparat und Verfahren zu seiner Herstellung
EP0759763A4 (en) * 1994-05-13 1997-07-30 Baxter Int PREVENTION OF HYPERACUTE REPELLATION OF ORGAN TRANSPLANTS FROM PIG TO PRIMATE
EP0804734B1 (en) * 1994-05-13 2005-05-04 Miltenyi Biotec GmbH Sterile and pyrogen-free columns coupled to protein for binding and removal of substances from blood
US6030614A (en) * 1994-05-13 2000-02-29 Plasmaselect Gmbh Teterow Ameliorating immunological rejection of allograft
DE69627333T2 (de) * 1995-06-26 2004-02-12 PerSeptive Biosystems, Inc., Framingham Automatisierte, kontinuierliche mehrdimensionale hochgeschwindigkeitsmolekularselektion und -analyse
DE19600939C1 (de) * 1996-01-12 1997-08-28 Immuno Ag Verfahren zur Trennung von IgG und IgA
US5868936A (en) * 1996-06-20 1999-02-09 Baxter International Inc. Affinity membrane system and method of using same
US7014049B2 (en) * 1996-12-23 2006-03-21 Glycorex Transplantation Ab Device for bio-affinity material
DE19705366C2 (de) * 1997-02-12 2002-08-01 Fresenius Ag Trägermaterial zur Reinigung proteinhaltiger Lösungen, Verfahren zur Herstellung des Trägermaterials und Verwendung des Trägermaterials
US6787523B1 (en) * 1997-12-02 2004-09-07 Neuralab Limited Prevention and treatment of amyloidogenic disease
CA2331607A1 (en) * 1998-05-06 1999-11-11 Temple University - Of The Commonwealth System Of Higher Education Reversal of proinflammatory response by ligating the macrophage fc.gamma.ri receptor
JP2002533169A (ja) * 1998-12-29 2002-10-08 オキュロジックス コーポレイション レオロジー的処置方法および関連するアフェレーシスシステム
US7163686B1 (en) * 1999-05-15 2007-01-16 The Regents Of The University Of California Protein A based binding domains with desirable activities
SE0001128D0 (sv) * 2000-03-30 2000-03-30 Amersham Pharm Biotech Ab A method of producing IgG
GB0007681D0 (en) * 2000-03-31 2000-05-17 Iatros Ltd Micro-organism inactivation system
US20020009445A1 (en) * 2000-07-12 2002-01-24 Yansheng Du Human beta-amyloid antibody and use thereof for treatment of alzheimer's disease
US20030099633A1 (en) * 2001-10-09 2003-05-29 Campbell Joy M. Methods and compositions for treatment of immune dysfunction disorders
US6582386B2 (en) * 2001-03-06 2003-06-24 Baxter International Inc. Multi-purpose, automated blood and fluid processing systems and methods
US20020172676A1 (en) * 2001-05-16 2002-11-21 George Jackowski Method of treatment of alzheimer's disease and device therefor
GB0112363D0 (en) 2001-05-21 2001-07-11 Allied Therapeutics Ltd Method and apparatus for treating biological fluids
CA2462682A1 (en) * 2001-10-04 2003-04-10 Protein Therapeutics, Inc. The use of gammaglobulin for the treatment of immune-mediated diseases
AU2003303198A1 (en) * 2002-12-19 2004-07-14 New York University Method for treating amyloid disease
WO2004072647A1 (en) * 2003-02-07 2004-08-26 Beyond Genomics Removal of proteins from a sample
DE10339342B3 (de) * 2003-08-25 2005-01-20 Fresenius Medical Care Deutschland Gmbh Blutbehandlungsvorrichtung
AT413336B (de) * 2003-09-12 2006-02-15 Mattner Frank Dr Apherese-vorrichtung
WO2005047334A1 (en) * 2003-11-13 2005-05-26 Hanmi Pharmaceutical. Co., Ltd. Igg fc fragment for a drug carrier and method for the preparation thereof
EP2394652A3 (en) * 2004-02-06 2012-10-24 Elan Pharmaceuticals Inc. Methods and compositions for treating tumors and metastatic disease
US7794720B2 (en) * 2004-02-18 2010-09-14 Plasma Ventures Pty Ltd Isolated plasma and method for hyperimmunisation and plasma collection
US20060030027A1 (en) * 2004-08-04 2006-02-09 Aspira Biosystems, Inc. Capture and removal of biomolecules from body fluids using partial molecular imprints
WO2006024038A2 (en) * 2004-08-27 2006-03-02 Codman & Shurtleff Light-based implant for treating alzheimer’s disease
ES2376777T3 (es) * 2004-09-07 2012-03-16 Velico Medical, Inc. Aparato para prolongar la supervivencia de plaquetas
CN101160133B (zh) * 2004-11-05 2013-01-09 普罗瑟拉生物公司 治疗用途的来自人血浆的内-α抑制剂蛋白质的制备和组合物
AR056142A1 (es) * 2005-10-21 2007-09-19 Amgen Inc Metodos para generar el anticuerpo igg monovalente
US20070092508A1 (en) * 2005-10-21 2007-04-26 Recombiant Technologies, Llc Detoxification depot for Alzheimer's disease
US20090246191A1 (en) * 2007-10-11 2009-10-01 University Of Tennessee Research Foundation Preparation of Purified Covalently Cross-linked Abeta Oligomers and Uses Thereof
US20100158893A1 (en) * 2008-12-19 2010-06-24 Baxter International Inc. Systems and methods for obtaining immunoglobulin from blood

Also Published As

Publication number Publication date
US20100158893A1 (en) 2010-06-24
MX2011006608A (es) 2011-07-12
KR20110114555A (ko) 2011-10-19
US20130052188A1 (en) 2013-02-28
JP2012512720A (ja) 2012-06-07
EP2385850B1 (en) 2014-03-26
CN102256641A (zh) 2011-11-23
JP5689425B2 (ja) 2015-03-25
AU2009327420A1 (en) 2011-07-14
ES2474740T3 (es) 2014-07-09
WO2010071809A1 (en) 2010-06-24
EP2385850A1 (en) 2011-11-16
CN105999450A (zh) 2016-10-12
US20120230872A1 (en) 2012-09-13
US20130011387A1 (en) 2013-01-10
AU2009327420B2 (en) 2014-09-18

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Legal Events

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B25A Requested transfer of rights approved

Owner name: BAXALTA GMBH (CH) , BAXALTA INCORPORATED (US)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2494 DE 23-10-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.