BRPI0921078A2 - excipiente coprocessado à base de fosfato de cálcio dibásico granular de alta funcionalidade e diretamente compressível. - Google Patents

excipiente coprocessado à base de fosfato de cálcio dibásico granular de alta funcionalidade e diretamente compressível.

Info

Publication number
BRPI0921078A2
BRPI0921078A2 BRPI0921078A BRPI0921078A BRPI0921078A2 BR PI0921078 A2 BRPI0921078 A2 BR PI0921078A2 BR PI0921078 A BRPI0921078 A BR PI0921078A BR PI0921078 A BRPI0921078 A BR PI0921078A BR PI0921078 A2 BRPI0921078 A2 BR PI0921078A2
Authority
BR
Brazil
Prior art keywords
functionality
calcium phosphate
dibasic calcium
directly compressible
based excipient
Prior art date
Application number
BRPI0921078A
Other languages
English (en)
Inventor
James Farina
Liliana Miinea
Nandu Deorkar
Sameer Randive
Original Assignee
Avantor Performance Mat Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avantor Performance Mat Inc filed Critical Avantor Performance Mat Inc
Publication of BRPI0921078A2 publication Critical patent/BRPI0921078A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
BRPI0921078A 2008-11-20 2009-11-13 excipiente coprocessado à base de fosfato de cálcio dibásico granular de alta funcionalidade e diretamente compressível. BRPI0921078A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11634908P 2008-11-20 2008-11-20
PCT/US2009/064289 WO2010059506A1 (en) 2008-11-20 2009-11-13 Directly compressible high functionality granular dibasic calcium phosphate based co-processed excipient

Publications (1)

Publication Number Publication Date
BRPI0921078A2 true BRPI0921078A2 (pt) 2015-12-15

Family

ID=41611341

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0921078A BRPI0921078A2 (pt) 2008-11-20 2009-11-13 excipiente coprocessado à base de fosfato de cálcio dibásico granular de alta funcionalidade e diretamente compressível.

Country Status (13)

Country Link
US (1) US20110229527A1 (pt)
EP (1) EP2365799A1 (pt)
JP (2) JP2012509326A (pt)
KR (1) KR20110086741A (pt)
CN (1) CN102215823A (pt)
AU (1) AU2009316876A1 (pt)
BR (1) BRPI0921078A2 (pt)
CA (1) CA2744377A1 (pt)
IL (1) IL212954A0 (pt)
MX (1) MX2011005167A (pt)
SG (1) SG171362A1 (pt)
TW (1) TW201023894A (pt)
WO (1) WO2010059506A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015063521A (ja) * 2013-09-02 2015-04-09 科研製薬株式会社 高い薬物含有率を有する錠剤及びその製造方法
US20170157582A1 (en) * 2014-07-02 2017-06-08 Corning Incorporated Spray drying mixed batch material for plasma melting
CN104189915B (zh) * 2014-07-30 2016-08-10 上海新亚药业闵行有限公司 一种固体制剂预混剂及其制备方法
JP6742197B2 (ja) * 2016-08-29 2020-08-19 信越化学工業株式会社 ヒプロメロースフタル酸エステルの製造方法
US20220000784A1 (en) * 2018-10-04 2022-01-06 Chemische Fabrik Budenheim Kg Spherical beads for use in producing pharmaceutically active pellets
EP3892262A1 (en) * 2020-04-06 2021-10-13 Chemische Fabrik Budenheim KG Beads comprising a buffer system

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3505433A1 (de) * 1985-02-16 1986-08-21 Basf Ag, 6700 Ludwigshafen Direkttablettierhilfsmittel
US4675188A (en) * 1985-08-02 1987-06-23 Stauffer Chemical Company Granular anhydrous dicalcium phosphate compositions suitable for direct compression tableting
US6277408B1 (en) * 1998-02-09 2001-08-21 Southwest Research Institute Silicate-containing powders providing controlled, sustained gas release
EP1008353A1 (en) * 1998-04-24 2000-06-14 Fuji Chemical Industry Co., Ltd. Saccharide-containing compositions
US6635281B2 (en) * 1998-12-23 2003-10-21 Alza Corporation Gastric retaining oral liquid dosage form
EP1239844B1 (en) * 1999-12-20 2005-06-08 Nicholas J. Kerkhof Process for producing nanometer particles by fluid bed spray-drying
GB0003782D0 (en) * 2000-02-17 2000-04-05 Dumex Ltd As Process
US6761905B2 (en) * 2001-05-01 2004-07-13 Wei Ming Pharmaceutical Mfg. Co., Ltd. Process for the preparation of direct tabletting formulations and aids
KR100425226B1 (ko) * 2001-07-03 2004-03-30 주식회사 팜트리 아세클로페낙을 함유하는 경제적인 경구용 제제의 조성 및제법
US20060057207A1 (en) * 2001-11-30 2006-03-16 Pfizer Inc Fast-disintegrating dosage forms of 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene
JP2005515212A (ja) * 2001-12-21 2005-05-26 ファイザー・プロダクツ・インク アジスロマイシンの湿式造粒法
EP1549294A1 (en) * 2002-10-11 2005-07-06 Vectura Limited Pharmaceutical excipients comprising inorganic particles in association with an organic polymeric material and forming a solid reticulated matrix, compositions, manufacturing and use thereof
US6703044B1 (en) * 2002-10-25 2004-03-09 Dexcel Pharma Tech, Ltd Venlafaxine formulations
US9107804B2 (en) * 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
US7364755B2 (en) * 2003-07-07 2008-04-29 Synthon Ip Inc. Modified calcium phosphate excipient
JP3841804B2 (ja) * 2003-10-15 2006-11-08 富士化学工業株式会社 口腔内速崩壊性錠剤用の組成物
EP1691789B1 (en) * 2003-11-25 2017-12-20 SmithKline Beecham (Cork) Limited Carvedilol free base, salts, anhydrous forms or solvate thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods
US7645459B2 (en) * 2004-05-24 2010-01-12 The Procter & Gamble Company Dosage forms of bisphosphonates
US20060067953A1 (en) * 2004-09-29 2006-03-30 Conforma Therapeutics Corporation Oral pharmaceutical formulations and methods for producing and using same
EP1845950A2 (en) * 2005-02-03 2007-10-24 Nycomed Pharma AS Fast wet-massing method for the preparation of calcium-containing compositions
US20070105927A1 (en) * 2005-10-20 2007-05-10 Glenmark Pharmaceuticals Limited Amorphous rizatriptan benzoate
AR057946A1 (es) * 2005-11-28 2007-12-26 Orexigen Therapeutics Inc Formulacion de zonisamida de liberacion sostenidda
AU2006318349B2 (en) * 2005-11-28 2010-08-19 Marinus Pharmaceuticals Ganaxolone formulations and methods for the making and use thereof
US20070148211A1 (en) * 2005-12-15 2007-06-28 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for oral administration
WO2007071240A1 (en) * 2005-12-23 2007-06-28 Niro A/S A plant and a process for production of tablets
WO2008020990A1 (en) * 2006-08-09 2008-02-21 Mallinckrodt Baker, Inc. New direct compressible excipient blend

Also Published As

Publication number Publication date
EP2365799A1 (en) 2011-09-21
JP2012509326A (ja) 2012-04-19
US20110229527A1 (en) 2011-09-22
CA2744377A1 (en) 2010-05-27
SG171362A1 (en) 2011-07-28
WO2010059506A1 (en) 2010-05-27
JP2014148556A (ja) 2014-08-21
AU2009316876A1 (en) 2011-07-07
CN102215823A (zh) 2011-10-12
TW201023894A (en) 2010-07-01
IL212954A0 (en) 2011-07-31
MX2011005167A (es) 2011-05-30
KR20110086741A (ko) 2011-07-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2386 DE 27-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.