BRPI0920756A2 - derivado de isoquinolinona - Google Patents
derivado de isoquinolinonaInfo
- Publication number
- BRPI0920756A2 BRPI0920756A2 BRPI0920756A BRPI0920756A BRPI0920756A2 BR PI0920756 A2 BRPI0920756 A2 BR PI0920756A2 BR PI0920756 A BRPI0920756 A BR PI0920756A BR PI0920756 A BRPI0920756 A BR PI0920756A BR PI0920756 A2 BRPI0920756 A2 BR PI0920756A2
- Authority
- BR
- Brazil
- Prior art keywords
- isoquinolinone derivative
- isoquinolinone
- derivative
- Prior art date
Links
- VDBNYAPERZTOOF-UHFFFAOYSA-N isoquinolin-1(2H)-one Chemical class C1=CC=C2C(=O)NC=CC2=C1 VDBNYAPERZTOOF-UHFFFAOYSA-N 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10176408P | 2008-10-01 | 2008-10-01 | |
| US17941709P | 2009-05-19 | 2009-05-19 | |
| PCT/SE2009/000432 WO2010039079A1 (en) | 2008-10-01 | 2009-10-01 | Isoquinolinone derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0920756A2 true BRPI0920756A2 (pt) | 2019-09-24 |
Family
ID=42073703
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0920756A BRPI0920756A2 (pt) | 2008-10-01 | 2009-10-01 | derivado de isoquinolinona |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8012980B2 (enExample) |
| EP (1) | EP2344472A4 (enExample) |
| JP (1) | JP2012504601A (enExample) |
| KR (1) | KR20110067051A (enExample) |
| CN (1) | CN102245593A (enExample) |
| AR (1) | AR073711A1 (enExample) |
| AU (1) | AU2009300456B2 (enExample) |
| BR (1) | BRPI0920756A2 (enExample) |
| CA (1) | CA2737434A1 (enExample) |
| MX (1) | MX2011003489A (enExample) |
| RU (1) | RU2512318C2 (enExample) |
| TW (1) | TW201018665A (enExample) |
| UY (1) | UY32154A (enExample) |
| WO (1) | WO2010039079A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103957711A (zh) | 2011-07-04 | 2014-07-30 | 拜耳知识产权有限责任公司 | 取代的异喹啉酮、异喹啉二酮、异喹啉三酮和二氢异喹啉酮或其各自的盐作为活性剂对抗植物非生物胁迫的用途 |
| US12496297B1 (en) * | 2020-10-23 | 2025-12-16 | Washington University | Compositions of autophagy modulating agents and uses thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA01009307A (es) | 1999-03-17 | 2002-07-30 | Astrazeneca Ab | Derivados de amida. |
| AU2003211931A1 (en) | 2002-02-13 | 2003-09-04 | Takeda Chemical Industries, Ltd. | Jnk inhibitor |
| JP2004143134A (ja) * | 2002-02-13 | 2004-05-20 | Takeda Chem Ind Ltd | Ｊｎｋ阻害剤 |
| US6867320B2 (en) | 2002-02-21 | 2005-03-15 | Asahi Kasei Pharma Corporation | Substituted phenylalkanoic acid derivatives and use thereof |
| WO2003076405A1 (en) | 2002-03-14 | 2003-09-18 | Bayer Healthcare Ag | Monocyclic aroylpyridinones as antiinflammatory agents |
| RU2297411C2 (ru) * | 2002-10-01 | 2007-04-20 | Мицубиси Фарма Корпорейшн | Изохинолиновые соединения, промежуточные соединения, способы их получения и применение |
| JP2007528362A (ja) | 2003-08-14 | 2007-10-11 | 旭化成ファーマ株式会社 | 置換アリールアルカン酸誘導体及びその用途 |
| JP2007008816A (ja) | 2003-10-15 | 2007-01-18 | Ube Ind Ltd | 新規イソキノリン誘導体 |
| BRPI0417345A (pt) | 2003-12-03 | 2007-03-13 | Cytopia Res Pty Ltd | compostos inibidores de quìnase baseados em azola, composições e seus usos |
| GB0402812D0 (en) | 2004-02-09 | 2004-03-10 | Tanabe Seiyaku Co | Novel compounds |
| JP2008504363A (ja) | 2004-06-29 | 2008-02-14 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | Ｐ２ｘ７受容体のベンズアミド阻害剤を利用する併用療法 |
| US20070054916A1 (en) * | 2004-10-01 | 2007-03-08 | Amgen Inc. | Aryl nitrogen-containing bicyclic compounds and methods of use |
| US7786115B2 (en) * | 2004-12-24 | 2010-08-31 | Astrazeneca Ab | Amide derivatives |
| GB0428326D0 (en) * | 2004-12-24 | 2005-02-02 | Astrazeneca Ab | Amide derivatives |
| KR101336678B1 (ko) | 2005-07-26 | 2013-12-04 | 사노피 | Ｒｈｏ-키나제 억제제로서의 사이클로헥실아민 이소퀴놀론유도체 |
| GB0608837D0 (en) | 2006-05-04 | 2006-06-14 | Chroma Therapeutics Ltd | Inhibitors of MAP kinase |
| HUE033281T2 (en) | 2006-05-04 | 2017-11-28 | Chroma Therapeutics Ltd | p38 mitogen-activated protein (MAP) kinase inhibitors |
| TW200808771A (en) | 2006-05-08 | 2008-02-16 | Astrazeneca Ab | Novel compounds II |
| TW200845988A (en) * | 2007-04-05 | 2008-12-01 | Astrazeneca Ab | New compounds and their uses 707 |
| HRP20141174T1 (hr) | 2007-06-27 | 2015-02-13 | Astrazeneca Ab | Derivati pirazinona i njihova uporaba za lijeäśenje bolesti pluä†a |
-
2009
- 2009-09-29 AR ARP090103762A patent/AR073711A1/es unknown
- 2009-09-30 TW TW098133161A patent/TW201018665A/zh unknown
- 2009-09-30 UY UY0001032154A patent/UY32154A/es unknown
- 2009-10-01 JP JP2011530023A patent/JP2012504601A/ja not_active Ceased
- 2009-10-01 WO PCT/SE2009/000432 patent/WO2010039079A1/en not_active Ceased
- 2009-10-01 CN CN2009801481701A patent/CN102245593A/zh active Pending
- 2009-10-01 KR KR1020117009801A patent/KR20110067051A/ko not_active Withdrawn
- 2009-10-01 BR BRPI0920756A patent/BRPI0920756A2/pt not_active IP Right Cessation
- 2009-10-01 AU AU2009300456A patent/AU2009300456B2/en not_active Ceased
- 2009-10-01 MX MX2011003489A patent/MX2011003489A/es active IP Right Grant
- 2009-10-01 US US12/571,894 patent/US8012980B2/en not_active Expired - Fee Related
- 2009-10-01 EP EP09818051A patent/EP2344472A4/en not_active Withdrawn
- 2009-10-01 RU RU2011113437/04A patent/RU2512318C2/ru not_active IP Right Cessation
- 2009-10-01 CA CA2737434A patent/CA2737434A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2512318C2 (ru) | 2014-04-10 |
| EP2344472A4 (en) | 2012-11-28 |
| US20100099665A1 (en) | 2010-04-22 |
| US8012980B2 (en) | 2011-09-06 |
| CA2737434A1 (en) | 2010-04-08 |
| UY32154A (es) | 2010-04-30 |
| MX2011003489A (es) | 2011-05-02 |
| EP2344472A1 (en) | 2011-07-20 |
| AU2009300456B2 (en) | 2012-04-12 |
| RU2011113437A (ru) | 2012-11-10 |
| TW201018665A (en) | 2010-05-16 |
| CN102245593A (zh) | 2011-11-16 |
| WO2010039079A1 (en) | 2010-04-08 |
| AR073711A1 (es) | 2010-11-24 |
| AU2009300456A1 (en) | 2010-04-08 |
| KR20110067051A (ko) | 2011-06-20 |
| JP2012504601A (ja) | 2012-02-23 |
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