BRPI0919827A2 - processo aperfeiçoado para peguilacao de proteínas - Google Patents

processo aperfeiçoado para peguilacao de proteínas

Info

Publication number
BRPI0919827A2
BRPI0919827A2 BRPI0919827A BRPI0919827A BRPI0919827A2 BR PI0919827 A2 BRPI0919827 A2 BR PI0919827A2 BR PI0919827 A BRPI0919827 A BR PI0919827A BR PI0919827 A BRPI0919827 A BR PI0919827A BR PI0919827 A2 BRPI0919827 A2 BR PI0919827A2
Authority
BR
Brazil
Prior art keywords
improved process
protein pegylation
pegylation
protein
improved
Prior art date
Application number
BRPI0919827A
Other languages
English (en)
Inventor
Aruna Khare
Divya Lal Saksena
Digamber Shripati Pawar
Dilip Kumar Rana
Dineshi Kumar Paliwal
Muralidharan Chandrakesan
Nikhil Umesh Mohe
Nilesh Dagdu Patil
Pankaj Prabhakar Malpure
Radharkrishnan Venkatsubramanian Tarur
Rakesh Shekhawat
Sagar Satyanarayan Zawar
Original Assignee
Usv Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Ltd filed Critical Usv Ltd
Publication of BRPI0919827A2 publication Critical patent/BRPI0919827A2/pt
Publication of BRPI0919827A8 publication Critical patent/BRPI0919827A8/pt
Publication of BRPI0919827B1 publication Critical patent/BRPI0919827B1/pt
Publication of BRPI0919827B8 publication Critical patent/BRPI0919827B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0919827A 2008-10-20 2009-05-04 processos para aumentar o rendimento de uma reação de peguilação de r-methug-csf processo para a produção em escala grama de peg- r-methug-csf BRPI0919827B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2261MU2008 2008-10-20
PCT/IN2009/000262 WO2010089756A2 (en) 2008-10-20 2009-05-04 An improved process for pegylation of proteins

Publications (4)

Publication Number Publication Date
BRPI0919827A2 true BRPI0919827A2 (pt) 2016-02-10
BRPI0919827A8 BRPI0919827A8 (pt) 2018-04-17
BRPI0919827B1 BRPI0919827B1 (pt) 2020-04-07
BRPI0919827B8 BRPI0919827B8 (pt) 2021-05-25

Family

ID=42542457

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0919827A BRPI0919827B8 (pt) 2008-10-20 2009-05-04 processos para aumentar o rendimento de uma reação de peguilação de r-methug-csf processo para a produção em escala grama de peg- r-methug-csf

Country Status (7)

Country Link
US (1) US8586710B2 (pt)
EP (1) EP2337794B1 (pt)
BR (1) BRPI0919827B8 (pt)
CA (1) CA2741209C (pt)
MX (1) MX2011004195A (pt)
RU (1) RU2472806C1 (pt)
WO (1) WO2010089756A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014257131B9 (en) 2013-04-23 2019-12-05 Nizyme, Inc. Methods and compositions for treating diseases
WO2017066525A1 (en) * 2015-10-14 2017-04-20 The Johns Hopkins University Protein bioconjugation method
USD849464S1 (en) 2017-09-19 2019-05-28 Whirlpool Corporation Coffee maker
EP3902820A2 (en) * 2018-12-28 2021-11-03 Coherus Biosciences, Inc. Process for producing, isolating, and purifying modified recombinant proteins

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2006596C (en) * 1988-12-22 2000-09-05 Rika Ishikawa Chemically-modified g-csf
US5824784A (en) * 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
AU9558901A (en) 2000-10-05 2002-04-15 Ares Trading Sa Regioselective liquid phase pegylation
EP1835938B1 (en) * 2004-12-27 2013-08-07 Baxter International Inc. Polymer-von willebrand factor-conjugates
EP2041167B1 (en) 2006-07-25 2010-05-12 Lipoxen Technologies Limited Derivatisation of granulocyte colony-stimulating factor
US20090252703A1 (en) 2006-10-19 2009-10-08 Gegg Jr Colin V Use of alcohol co-solvents to improve pegylation reaction yields
US20100035814A1 (en) 2006-11-09 2010-02-11 Novo Nordisk A/S N-Terminal Pegylated Prolactin Receptor Molecules

Also Published As

Publication number Publication date
BRPI0919827A8 (pt) 2018-04-17
WO2010089756A2 (en) 2010-08-12
BRPI0919827B1 (pt) 2020-04-07
RU2011120170A (ru) 2012-11-27
WO2010089756A3 (en) 2010-12-16
RU2472806C1 (ru) 2013-01-20
CA2741209C (en) 2016-12-20
US20110196134A1 (en) 2011-08-11
MX2011004195A (es) 2011-09-27
BRPI0919827B8 (pt) 2021-05-25
US8586710B2 (en) 2013-11-19
EP2337794A2 (en) 2011-06-29
CA2741209A1 (en) 2010-08-12
EP2337794B1 (en) 2013-07-31

Similar Documents

Publication Publication Date Title
BRPI0821944A2 (pt) Processo
BRPI0918349A2 (pt) Processo para preparar dióxido de divinilareno
BRPI0812448A2 (pt) Método para aperfeiçoamento de propriedades de proteína
BRPI0919868A2 (pt) processo
SMT201400100B (it) Processo migliorato
BRPI0920920A2 (pt) processo para dessulfuração
BRPI0921106A2 (pt) biocombustível e processo para preparação de biocombustível
BRPI0810850A2 (pt) Processo para carbonilação de dimetil éter
BRPI0816911A2 (pt) Processo para preparação de 4-aminobut-2-enolidas
BRPI0915854A2 (pt) Processo para preparar óxido de etileno
BRPI0810846A2 (pt) Processo para carbonilção de dimetil éter
BRPI0813660A2 (pt) Processo para o cultivo de microalgas
BRPI0921374A2 (pt) processo
BRPI0919241A8 (pt) processo para fabricação de compostos de quinolona
BRPI0909004A2 (pt) Processo para produção de biogás
BRPI0813960A2 (pt) Processo para produção de biarilas
BRPI1012134A2 (pt) processo de carbolinação
BR112012001462A2 (pt) processo para preparar metil mercaptano.
BRPI0921420A2 (pt) processo para preparar compostos
BRPI1007573A2 (pt) processo
BRPI0920689A2 (pt) processo para produção de cumeno
BRPI0816237A2 (pt) Processo de ciclopropanação
BR112013014949A2 (pt) processo para produção de proteína
BRPI0917836A2 (pt) processo para preparar uretanos
BRPI0813788A2 (pt) Processo para preparação de metacrilato de alila

Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Ipc: C07K 14/535 (2006.01), A61K 47/60 (2017.01)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25D Requested change of name of applicant approved

Owner name: USV PRIVATE LIMITED (IN)

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 07/04/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 04/05/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 14A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2721 DE 28-02-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.