BRPI0915036A2 - processo de produção de caspofungina e seus intermediários - Google Patents

processo de produção de caspofungina e seus intermediários

Info

Publication number
BRPI0915036A2
BRPI0915036A2 BRPI0915036A BRPI0915036A BRPI0915036A2 BR PI0915036 A2 BRPI0915036 A2 BR PI0915036A2 BR PI0915036 A BRPI0915036 A BR PI0915036A BR PI0915036 A BRPI0915036 A BR PI0915036A BR PI0915036 A2 BRPI0915036 A2 BR PI0915036A2
Authority
BR
Brazil
Prior art keywords
caspofungin
intermediates
production process
production
caspofungin production
Prior art date
Application number
BRPI0915036A
Other languages
English (en)
Inventor
Audun Heggelund
Ole Heine Kvernenes
Vidar Bjornstad
Original Assignee
Xellia Pharmaceuticals Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xellia Pharmaceuticals Aps filed Critical Xellia Pharmaceuticals Aps
Publication of BRPI0915036A2 publication Critical patent/BRPI0915036A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
BRPI0915036A 2008-06-13 2009-06-11 processo de produção de caspofungina e seus intermediários BRPI0915036A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/138,488 US8048853B2 (en) 2008-06-13 2008-06-13 Process for preparing pharmaceutical compound and intermediates thereof
PCT/NO2009/000218 WO2009151341A1 (en) 2008-06-13 2009-06-11 Process for preparing caspofungin and intermediates thereof

Publications (1)

Publication Number Publication Date
BRPI0915036A2 true BRPI0915036A2 (pt) 2015-10-27

Family

ID=41011915

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0915036A BRPI0915036A2 (pt) 2008-06-13 2009-06-11 processo de produção de caspofungina e seus intermediários

Country Status (15)

Country Link
US (1) US8048853B2 (pt)
EP (1) EP2307445B1 (pt)
JP (1) JP5604423B2 (pt)
CN (1) CN102112487B (pt)
AU (1) AU2009258343B2 (pt)
BR (1) BRPI0915036A2 (pt)
CA (1) CA2727567C (pt)
DK (1) DK2307445T3 (pt)
ES (1) ES2394059T3 (pt)
HR (1) HRP20121026T1 (pt)
IL (1) IL209919A (pt)
PL (1) PL2307445T3 (pt)
RU (1) RU2489442C2 (pt)
SI (1) SI2307445T1 (pt)
WO (1) WO2009151341A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010064219A1 (en) * 2008-12-04 2010-06-10 Ranbaxy Laboratories Limited Process for the preparation of a novel intermediate for caspofungin
WO2012041801A1 (en) * 2010-09-28 2012-04-05 Dsm Sinochem Pharmaceuticals Netherlands B.V. Method for isolating a cyclohexapeptide
KR101331984B1 (ko) * 2010-12-09 2013-11-25 종근당바이오 주식회사 카스포펀진 제조방법 및 그의 신규 중간체
CN102746384B (zh) * 2011-04-22 2016-01-20 上海天伟生物制药有限公司 一种高纯度的卡泊芬净或其盐及其制备方法和用途
CN103483426A (zh) * 2012-06-14 2014-01-01 博瑞生物医药技术(苏州)有限公司 一种氮杂环己肽的制备方法
CN112110991A (zh) * 2014-12-24 2020-12-22 上海天伟生物制药有限公司 一种含氮杂环六肽前体的组合物及其制备方法和用途
CN105440109B (zh) * 2015-11-26 2019-03-05 成都摩尔生物医药有限公司 一种卡泊芬净的制备方法
EP3620462A1 (en) 2018-09-04 2020-03-11 Xellia Pharmaceuticals ApS Process for the preparation of caspofungin
CN111808172B (zh) * 2019-04-12 2023-05-12 上海森辉医药有限公司 肺念菌素b0衍生物及其制备方法和用途
CN111233981A (zh) * 2020-03-17 2020-06-05 湖南欧亚药业有限公司 一种卡泊芬净的制备方法
CN113801202A (zh) * 2020-06-15 2021-12-17 杭州中美华东制药有限公司 一种醋酸卡泊芬净杂质g的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5336756A (en) * 1991-05-01 1994-08-09 Merck & Co., Inc. Process for crystalline cyclic lipopeptides
US6030944A (en) 1991-10-01 2000-02-29 Merck & Co., Inc. Cyclohexapeptidyl bisamine compounds
US5939384A (en) * 1991-10-01 1999-08-17 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
US5348940A (en) * 1991-10-01 1994-09-20 Merck & Co., Inc. Cyclohexapeptidyl hydroxypropionitrile compounds
US5378804A (en) 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
DE69528065T2 (de) * 1994-09-16 2003-04-10 Merck & Co Inc Azazyklohexapeptid-verbindungen
US5552521A (en) 1995-02-10 1996-09-03 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
US5952300A (en) * 1996-04-19 1999-09-14 Merck & Co., Inc. Antifungal compositions
PE63998A1 (es) 1996-04-19 1998-10-30 Merck & Co Inc Composiciones anti-fungosas
HRP970318B1 (en) * 1996-06-14 2002-06-30 Merck & Co Inc A process for preparing certain aza cyclohexapeptides
US5936062A (en) * 1997-06-12 1999-08-10 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
ATE416189T1 (de) 1999-07-27 2008-12-15 Aventis Pharma Gmbh Cyclohexapeptide, deren herstellung und verwendung in pharmazeutische zusammensetzungen
US7214768B2 (en) * 2002-04-08 2007-05-08 Merck & Co., Inc. Echinocandin process
US8436490B2 (en) 2005-08-30 2013-05-07 Abb Research Ltd. Wind mill power flow control with dump load and power converter
EP1785432A1 (en) 2005-11-15 2007-05-16 Sandoz AG Process and intermediates for the synthesis of caspofungin.

Also Published As

Publication number Publication date
PL2307445T3 (pl) 2013-03-29
CN102112487A (zh) 2011-06-29
US20090312541A1 (en) 2009-12-17
RU2489442C2 (ru) 2013-08-10
SI2307445T1 (sl) 2013-01-31
US8048853B2 (en) 2011-11-01
CN102112487B (zh) 2014-05-07
WO2009151341A1 (en) 2009-12-17
AU2009258343A1 (en) 2009-12-17
IL209919A (en) 2015-01-29
CA2727567C (en) 2014-08-05
EP2307445B1 (en) 2012-09-26
RU2011100815A (ru) 2012-07-20
ES2394059T3 (es) 2013-01-16
JP2011524871A (ja) 2011-09-08
IL209919A0 (en) 2011-02-28
HRP20121026T1 (hr) 2013-01-31
JP5604423B2 (ja) 2014-10-08
EP2307445A1 (en) 2011-04-13
CA2727567A1 (en) 2009-12-17
DK2307445T3 (da) 2013-01-14
AU2009258343B2 (en) 2012-09-13

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Legal Events

Date Code Title Description
B15I Others concerning applications: loss of priority

Free format text: PERDA DA PRIORIDADE US 12/138,488 DE 13/06/2008, CONFORME AS DISPOSICOES PREVISTAS NA LEI 9.279 DE 14/05/1996 (LPI) ART. 16 7O E NO ART. 28 DO ATO NORMATIVO 128/1997, POR NAO ATENDER AO DISPOSTO NO ART. 27 DO ATO NORMATIVO 128/1997, POIS NAO FOI APRESENTADA CESSAO DA REFERIDA PRIORIDADE, QUE POSSUI DEPOSITANTE DIFERENTE DO DEPOSITANTE DA FASE NACIONAL.

B12F Other appeals [chapter 12.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 9A E 10A ANUIDADE

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 NA RPI 2531 DE 09/07/2019