BRPI0914508B1 - ANTICORPOS MONOCLONAIS PARA A PROTEÍNA PBP2a, E, COMPOSIÇÃO FARMACÊUTICA - Google Patents

ANTICORPOS MONOCLONAIS PARA A PROTEÍNA PBP2a, E, COMPOSIÇÃO FARMACÊUTICA Download PDF

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Publication number
BRPI0914508B1
BRPI0914508B1 BRPI0914508-7A BRPI0914508A BRPI0914508B1 BR PI0914508 B1 BRPI0914508 B1 BR PI0914508B1 BR PI0914508 A BRPI0914508 A BR PI0914508A BR PI0914508 B1 BRPI0914508 B1 BR PI0914508B1
Authority
BR
Brazil
Prior art keywords
seq
pbp2a
mrsa
bacteria
sequence seq
Prior art date
Application number
BRPI0914508-7A
Other languages
English (en)
Portuguese (pt)
Inventor
José Procópio Moreno Senna
João Luiz Sampaio Queiroz
Nadia Maria Batoreu
Maria da Glória Martins Teixeira
Original Assignee
Fundação Oswaldo Cruz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundação Oswaldo Cruz filed Critical Fundação Oswaldo Cruz
Priority to BRPI0914508-7A priority Critical patent/BRPI0914508B1/pt
Priority to SG2012009205A priority patent/SG178346A1/en
Priority to CA2770771A priority patent/CA2770771C/en
Priority to CU2012000026A priority patent/CU24095B1/es
Priority to CU20140101A priority patent/CU24180B1/es
Priority to CN201080043628.XA priority patent/CN102741281B/zh
Priority to AU2010282162A priority patent/AU2010282162B2/en
Priority to JP2012524064A priority patent/JP5785544B2/ja
Priority to RU2012108941/10A priority patent/RU2575070C2/ru
Priority to KR1020127006442A priority patent/KR101868160B1/ko
Priority to CL2012000337A priority patent/CL2012000337A1/es
Priority to CO12041846A priority patent/CO6531407A2/es
Publication of BRPI0914508A2 publication Critical patent/BRPI0914508A2/pt
Priority to HK13103458.4A priority patent/HK1176077A1/xx
Publication of BRPI0914508B1 publication Critical patent/BRPI0914508B1/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/14Peptides, e.g. proteins
    • A61K49/16Antibodies; Immunoglobulins; Fragments thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BRPI0914508-7A 2009-08-10 2009-08-10 ANTICORPOS MONOCLONAIS PARA A PROTEÍNA PBP2a, E, COMPOSIÇÃO FARMACÊUTICA BRPI0914508B1 (pt)

Priority Applications (13)

Application Number Priority Date Filing Date Title
BRPI0914508-7A BRPI0914508B1 (pt) 2009-08-10 2009-08-10 ANTICORPOS MONOCLONAIS PARA A PROTEÍNA PBP2a, E, COMPOSIÇÃO FARMACÊUTICA
JP2012524064A JP5785544B2 (ja) 2009-08-10 2010-08-10 ファーミキューテス門に属する細菌による感染症の治療及び免疫学的診断のための、PBP2aまたはそれに相同な配列を持つタンパク質に対するモノクローナル抗体
RU2012108941/10A RU2575070C2 (ru) 2009-08-10 2010-08-10 МОНОКЛОНАЛЬНЫЕ АНТИТЕЛА ПРОТИВ БЕЛКА РВР2-А И ГОМОЛОГИЧНЫХ ПОСЛЕДОВАТЕЛЬНОСТЕЙ ДЛЯ ЛЕЧЕНИЯ ЗАРАЖЕНИЯ БАКТЕРИЯМИ И ИММУНОДИАГНОСТИКИ БАКТЕРИЙ ТИПА Firmicutes
CU2012000026A CU24095B1 (es) 2009-08-10 2010-08-10 ANTICUERPO MONOCLONAL AISLADO PARA PROTEÍNAS PBP2a
CU20140101A CU24180B1 (es) 2009-08-10 2010-08-10 Anticuerpo monoclonal aislado para proteina pbp5
CN201080043628.XA CN102741281B (zh) 2009-08-10 2010-08-10 PBP2-a蛋白的单克隆抗体和同源序列用于由厚壁菌门的细菌引起的免疫诊断和感染的处理
AU2010282162A AU2010282162B2 (en) 2009-08-10 2010-08-10 Monoclonal antibodies against the PBP2-a protein and homologous sequences for the treatment of infections by and immunodiagnostics of bacteria of the firmicutes phylum
SG2012009205A SG178346A1 (en) 2009-08-10 2010-08-10 Monoclonal antibodies against the pbp2-a protein and homologous sequences for the treatment of infections by and immunodiagnostics of bacteria of the firmicutes phylum
CA2770771A CA2770771C (en) 2009-08-10 2010-08-10 Monoclonal antibodies for pbp2-a protein and homologous sequences for treatment of infections and immunodiagnosis on bacteria from phylum firmicutes
KR1020127006442A KR101868160B1 (ko) 2009-08-10 2010-08-10 Pbp2-a 단백질용 단클론 항체 및 문 퍼미큐트 세균에 대한 면역진단 및 감염 치료를 위한 상동 서열
CL2012000337A CL2012000337A1 (es) 2009-08-10 2012-02-09 Anticuerpo monoclonal aislado que se une a la proteína pbp2a de una bacteria resistente a meticilina (mrsa), que comprende tanto los 3 cdrs de cadena liviana (sec nº6/7/8) como los 3 cdrs de cadena pesada (nº12/13/14); composición farmacéutica que lo comprende; método de diagnóstico; y su uso terapéutico para infecciones.
CO12041846A CO6531407A2 (es) 2009-08-10 2012-03-09 Anticuerpos monoclonales para proteína pbp2-a y secuencias homólogas para el tratamiento de infeciones e inmunodiagnóstico en bacterias del fílum firmicutes
HK13103458.4A HK1176077A1 (en) 2009-08-10 2013-03-20 Monoclonal antibodies against the pbp2-a protein and homologous sequences for the treatment of infections by and immunodiagnostics of bacteria of the firmicutes phylum pbp2-a

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0914508-7A BRPI0914508B1 (pt) 2009-08-10 2009-08-10 ANTICORPOS MONOCLONAIS PARA A PROTEÍNA PBP2a, E, COMPOSIÇÃO FARMACÊUTICA

Publications (2)

Publication Number Publication Date
BRPI0914508A2 BRPI0914508A2 (pt) 2012-05-02
BRPI0914508B1 true BRPI0914508B1 (pt) 2019-04-16

Family

ID=45994924

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0914508-7A BRPI0914508B1 (pt) 2009-08-10 2009-08-10 ANTICORPOS MONOCLONAIS PARA A PROTEÍNA PBP2a, E, COMPOSIÇÃO FARMACÊUTICA

Country Status (4)

Country Link
KR (1) KR101868160B1 (es)
BR (1) BRPI0914508B1 (es)
CL (1) CL2012000337A1 (es)
CO (1) CO6531407A2 (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5867100A (en) * 1999-05-03 2000-12-12 Medarex, Inc. Human antibodies to staphylococcus aureus

Also Published As

Publication number Publication date
CL2012000337A1 (es) 2012-10-19
BRPI0914508A2 (pt) 2012-05-02
KR101868160B1 (ko) 2018-06-15
CO6531407A2 (es) 2012-09-28
KR20120090968A (ko) 2012-08-17

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B03A Publication of an application: publication of a patent application or of a certificate of addition of invention
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B07D Technical examination (opinion) related to article 229 of industrial property law
B07E Notice of approval relating to section 229 industrial property law
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application according art. 36 industrial patent law
B09A Decision: intention to grant
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/08/2009, OBSERVADAS AS CONDICOES LEGAIS. (CO) 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/08/2009, OBSERVADAS AS CONDICOES LEGAIS