BRPI0911904B8 - sistema de radiaçao parcial da mama e material biocompativel e biodegradavel para uso em metodo de radiaçao parcial da mama - Google Patents

sistema de radiaçao parcial da mama e material biocompativel e biodegradavel para uso em metodo de radiaçao parcial da mama

Info

Publication number
BRPI0911904B8
BRPI0911904B8 BRPI0911904A BRPI0911904A BRPI0911904B8 BR PI0911904 B8 BRPI0911904 B8 BR PI0911904B8 BR PI0911904 A BRPI0911904 A BR PI0911904A BR PI0911904 A BRPI0911904 A BR PI0911904A BR PI0911904 B8 BRPI0911904 B8 BR PI0911904B8
Authority
BR
Brazil
Prior art keywords
partial breast
breast radiation
biocompatible
biodegradable material
partial
Prior art date
Application number
BRPI0911904A
Other languages
English (en)
Inventor
D Corbitt John Jr
Anthony Lori
Original Assignee
Senorx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40790758&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0911904(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Senorx Inc filed Critical Senorx Inc
Publication of BRPI0911904A2 publication Critical patent/BRPI0911904A2/pt
Publication of BRPI0911904B1 publication Critical patent/BRPI0911904B1/pt
Publication of BRPI0911904B8 publication Critical patent/BRPI0911904B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/12—Mammary prostheses and implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3904—Markers, e.g. radio-opaque or breast lesions markers specially adapted for marking specified tissue
    • A61B2090/3908—Soft tissue, e.g. breast tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3966—Radiopaque markers visible in an X-ray image
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1061—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using an x-ray imaging system having a separate imaging source

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Radiation-Therapy Devices (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

sistema para utilização de um implante para direcionar radiação de feixe externo. a presente invenção refere-se a um novo método de radiação parcial da mama utilizando um implante da mama, que pode prover um alvo estável e aperfeiçoado para o tratamento de radiação estereotática.
BRPI0911904A 2008-04-28 2009-04-24 sistema de radiaçao parcial da mama e material biocompativel e biodegradavel para uso em metodo de radiaçao parcial da mama BRPI0911904B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/110,748 2008-04-28
US12/110,748 US8288745B2 (en) 1997-10-10 2008-04-28 Method of utilizing an implant for targeting external beam radiation
PCT/US2009/002551 WO2009134340A1 (en) 2008-04-28 2009-04-24 System for utilizing an implant for targeting external beam radiation

Publications (3)

Publication Number Publication Date
BRPI0911904A2 BRPI0911904A2 (pt) 2019-03-06
BRPI0911904B1 BRPI0911904B1 (pt) 2020-12-08
BRPI0911904B8 true BRPI0911904B8 (pt) 2021-06-22

Family

ID=40790758

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0911904A BRPI0911904B8 (pt) 2008-04-28 2009-04-24 sistema de radiaçao parcial da mama e material biocompativel e biodegradavel para uso em metodo de radiaçao parcial da mama

Country Status (9)

Country Link
US (5) US8288745B2 (pt)
EP (1) EP2271404A1 (pt)
JP (1) JP2011518640A (pt)
KR (2) KR20160050093A (pt)
CN (1) CN102119046B (pt)
AU (1) AU2009241851B2 (pt)
BR (1) BRPI0911904B8 (pt)
CA (1) CA2722747C (pt)
WO (1) WO2009134340A1 (pt)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8668737B2 (en) 1997-10-10 2014-03-11 Senorx, Inc. Tissue marking implant
US8288745B2 (en) 1997-10-10 2012-10-16 Senorx, Inc. Method of utilizing an implant for targeting external beam radiation
US6862470B2 (en) 1999-02-02 2005-03-01 Senorx, Inc. Cavity-filling biopsy site markers
US8361082B2 (en) 1999-02-02 2013-01-29 Senorx, Inc. Marker delivery device with releasable plug
US9820824B2 (en) 1999-02-02 2017-11-21 Senorx, Inc. Deployment of polysaccharide markers for treating a site within a patent
US7983734B2 (en) 2003-05-23 2011-07-19 Senorx, Inc. Fibrous marker and intracorporeal delivery thereof
US6575991B1 (en) 1999-06-17 2003-06-10 Inrad, Inc. Apparatus for the percutaneous marking of a lesion
US20060036158A1 (en) 2003-11-17 2006-02-16 Inrad, Inc. Self-contained, self-piercing, side-expelling marking apparatus
US7877133B2 (en) 2003-05-23 2011-01-25 Senorx, Inc. Marker or filler forming fluid
US10357328B2 (en) 2005-04-20 2019-07-23 Bard Peripheral Vascular, Inc. and Bard Shannon Limited Marking device with retractable cannula
EP2109409B1 (en) 2006-12-12 2018-09-05 C.R.Bard, Inc. Multiple imaging mode tissue marker
US9327061B2 (en) 2008-09-23 2016-05-03 Senorx, Inc. Porous bioabsorbable implant
US8670818B2 (en) 2008-12-30 2014-03-11 C. R. Bard, Inc. Marker delivery device for tissue marker placement
US9014787B2 (en) 2009-06-01 2015-04-21 Focal Therapeutics, Inc. Bioabsorbable target for diagnostic or therapeutic procedure
CN102844054B (zh) 2009-12-15 2016-04-20 因赛普特有限责任公司 植入物和能生物降解的基准标记物
US8673003B1 (en) * 2010-07-20 2014-03-18 Abdullah Khalid Al Rasheed Method for improving the early detection of breast cancer and device therefor
US9943706B2 (en) 2012-01-12 2018-04-17 Surgical Radiation Products, Llc Targeting implant for external beam radiation
US9320517B2 (en) 2012-01-12 2016-04-26 Surgical Radiation Products, Llc Targeting implant for external beam radiation
US20130289389A1 (en) 2012-04-26 2013-10-31 Focal Therapeutics Surgical implant for marking soft tissue
CN105407955B (zh) * 2013-03-15 2018-11-13 波士顿科学公司 输送药物的装置和方法
CA2955956C (en) 2014-07-25 2022-10-18 Focal Therapeutics, Inc. Implantable devices and techniques for oncoplastic surgery
US10545166B2 (en) * 2015-05-08 2020-01-28 Fugro Technology B.V. Optical sensor device, sensor apparatus and cable comprising such device
USD752739S1 (en) 2015-08-13 2016-03-29 Robert G. Anderson Tabbed prosthesis insertion bellow
CN110891613B (zh) 2017-04-07 2022-08-26 观点医疗有限公司 多模式成像标记物
US11219502B2 (en) 2017-09-11 2022-01-11 Medtronic Advanced Energy, Llc Transformative shape-memory polymer tissue cavity marker devices, systems and deployment methods
US11324567B2 (en) 2018-02-01 2022-05-10 Medtronic Advanced Energy, Llc Expandable tissue cavity marker devices, systems and deployment methods
EP4021306A4 (en) 2019-08-28 2023-08-23 View Point Medical, Inc. ULTRASONIC MARKER DETECTION, MARKER AND ASSOCIATED SYSTEMS, METHODS AND ARTICLES
US11406489B2 (en) 2019-10-07 2022-08-09 Cornell University Implant with fiducial markers
US11903767B2 (en) 2019-11-27 2024-02-20 View Point Medical, Inc. Composite tissue markers detectable via multiple detection modalities
US11882992B2 (en) 2019-11-27 2024-01-30 View Point Medical, Inc. Composite tissue markers detectable via multiple detection modalities including radiopaque element

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US292630A (en) * 1884-01-29 Samuel k
US4470160A (en) 1980-11-21 1984-09-11 Cavon Joseph F Cast gel implantable prosthesis
US4740208A (en) 1980-11-21 1988-04-26 Cavon Joseph F Cast gel implantable prosthesis
US4298998A (en) 1980-12-08 1981-11-10 Naficy Sadeque S Breast prosthesis with biologically absorbable outer container
US4428082A (en) 1980-12-08 1984-01-31 Naficy Sadeque S Breast prosthesis with filling valve
US4682593A (en) * 1982-10-20 1987-07-28 Johnson Douglas W Adjustable breast bridge for use in multiple-plane interstitial breast implants
US4937323A (en) * 1984-03-27 1990-06-26 University Of Medicine And Dentistry Of New Jersey Method and apparatus for lidc enhanced wound healing using biocompatible tissue ingrowth implants
US4648880A (en) 1984-08-30 1987-03-10 Daniel Brauman Implantable prosthetic devices
US4795463A (en) * 1984-10-03 1989-01-03 Baylor College Of Medicine Labeled breast prosthesis and methods for detecting and predicting rupture of the prosthesis
US4574780A (en) * 1984-11-13 1986-03-11 Manders Ernest K Tissue expander and method
US4697575A (en) 1984-11-21 1987-10-06 Henry Ford Hospital Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member
US4863470A (en) * 1985-03-19 1989-09-05 Medical Engineering Corporation Identification marker for a breast prosthesis
US5628781A (en) 1985-06-06 1997-05-13 Thomas Jefferson University Implant materials, methods of treating the surface of implants with microvascular endothelial cells, and the treated implants themselves
US4902288A (en) * 1985-12-03 1990-02-20 Marylou Ingram Implantable immunotherapy system using stimulated cells
US5120802A (en) 1987-12-17 1992-06-09 Allied-Signal Inc. Polycarbonate-based block copolymers and devices
US4950665A (en) 1988-10-28 1990-08-21 Oklahoma Medical Research Foundation Phototherapy using methylene blue
WO1990009152A1 (en) 1989-02-15 1990-08-23 Microtek Medical, Inc. Biocompatible material and prosthesis
US4995882A (en) * 1989-08-28 1991-02-26 Washington University Radiolucent breast implant
US5199056A (en) * 1989-11-28 1993-03-30 Darrah Carol J Mammography compression paddle
US5192744A (en) * 1990-01-12 1993-03-09 Northwestern University Method of inhibiting angiogenesis of tumors
US5147398A (en) * 1990-05-04 1992-09-15 Lynn Lawrence A Multiple compartment breast prosthesis
US5342283A (en) * 1990-08-13 1994-08-30 Good Roger R Endocurietherapy
US6099457A (en) * 1990-08-13 2000-08-08 Endotech, Inc. Endocurietherapy
EP0475077B1 (en) 1990-09-10 1996-06-12 Synthes AG, Chur Bone regeneration membrane
WO1993007913A1 (en) * 1991-10-24 1993-04-29 Children's Medical Center Corporation Neomorphogenesis of urological structures in vivo from cell culture
US5534023A (en) * 1992-12-29 1996-07-09 Henley; Julian L. Fluid filled prosthesis excluding gas-filled beads
EP0636015A4 (en) 1993-01-19 1995-08-02 Hang Fu Lee DEVICE AND METHOD FOR IMPLANTABLE PROSTHESES.
US5480430A (en) * 1993-06-04 1996-01-02 Mcghan Medical Corporation Shape-retaining shell for a fluid filled prosthesis
US5451789A (en) * 1993-07-19 1995-09-19 Board Of Regents, The University Of Texas System High performance positron camera
US5676698A (en) 1993-09-07 1997-10-14 Datascope Investment Corp. Soft tissue implant
US5626611A (en) 1994-02-10 1997-05-06 United States Surgical Corporation Composite bioabsorbable materials and surgical articles made therefrom
DE69534233T2 (de) 1994-09-16 2005-10-27 Ethicon Endo-Surgery, Inc., Cincinnati Vorrichtungen zum bestimmen und markieren von gewebe
US5716404A (en) * 1994-12-16 1998-02-10 Massachusetts Institute Of Technology Breast tissue engineering
GB2301362B (en) * 1995-05-30 1999-01-06 Johnson & Johnson Medical Absorbable implant materials having controlled porosity
US5692511A (en) * 1995-06-07 1997-12-02 Grable; Richard J. Diagnostic tomographic laser imaging apparatus
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US5824081A (en) 1996-09-13 1998-10-20 Lipomatrix Incorporated Hydraulic foam tissue implant
US5676146B1 (en) * 1996-09-13 2000-04-18 Osteotech Inc Surgical implant containing a resorbable radiopaque marker and method of locating such within a body
US5766222A (en) * 1997-07-07 1998-06-16 Petit; Michael G. Nipple illuminator for photodynamic therapy
US5854382A (en) 1997-08-18 1998-12-29 Meadox Medicals, Inc. Bioresorbable compositions for implantable prostheses
US6316522B1 (en) 1997-08-18 2001-11-13 Scimed Life Systems, Inc. Bioresorbable hydrogel compositions for implantable prostheses
US6638308B2 (en) * 1997-10-10 2003-10-28 John D. Corbitt, Jr. Bioabsorbable breast implant
US8288745B2 (en) * 1997-10-10 2012-10-16 Senorx, Inc. Method of utilizing an implant for targeting external beam radiation
AU1070899A (en) * 1997-10-10 1999-05-03 Corbitt, John D. Jr. Breast implant
US7637948B2 (en) * 1997-10-10 2009-12-29 Senorx, Inc. Tissue marking implant
US6015541A (en) * 1997-11-03 2000-01-18 Micro Therapeutics, Inc. Radioactive embolizing compositions
WO1999024490A1 (en) * 1997-11-07 1999-05-20 Rutgers, The State University Strictly alternating poly(alkylene oxide ether) copolymers
US6270464B1 (en) * 1998-06-22 2001-08-07 Artemis Medical, Inc. Biopsy localization method and device
US6451871B1 (en) 1998-11-25 2002-09-17 Novartis Ag Methods of modifying surface characteristics
US6118848A (en) 1998-01-14 2000-09-12 Reiffel; Leonard System to stabilize an irradiated internal target
US6161034A (en) 1999-02-02 2000-12-12 Senorx, Inc. Methods and chemical preparations for time-limited marking of biopsy sites
US6263880B1 (en) * 1998-06-22 2001-07-24 Neovasys, Inc. Method of enhancing blood flow in tissue
US6220248B1 (en) * 1998-10-21 2001-04-24 Ethicon Endo-Surgery, Inc. Method for implanting a biopsy marker
US6356782B1 (en) * 1998-12-24 2002-03-12 Vivant Medical, Inc. Subcutaneous cavity marking device and method
US6144875A (en) * 1999-03-16 2000-11-07 Accuray Incorporated Apparatus and method for compensating for respiratory and patient motion during treatment
US6432138B1 (en) * 2000-03-07 2002-08-13 Promatrx, Inc. Controlled porosity 3-D fabric breast prosthesis
US6991652B2 (en) 2000-06-13 2006-01-31 Burg Karen J L Tissue engineering composite
US6913626B2 (en) 2001-08-14 2005-07-05 Mcghan Jim J. Medical implant having bioabsorbable textured surface
US6726482B2 (en) * 2002-03-13 2004-04-27 Garry Tsaur Tooth whitening means
WO2004111802A2 (en) * 2003-04-02 2004-12-23 Sicel Technologies, Inc. Methods, systems, and computer program products for providing dynamic data of positional localization of target implants
US7877133B2 (en) * 2003-05-23 2011-01-25 Senorx, Inc. Marker or filler forming fluid
US20050015049A1 (en) * 2003-07-16 2005-01-20 Rioux Robert F. Temporary tissue spacer and pretreatment balloon
US7537788B2 (en) * 2003-07-25 2009-05-26 Rubicor Medical, Inc. Post-biopsy cavity treatment implants and methods
US20050059887A1 (en) * 2003-09-16 2005-03-17 Hassan Mostafavi Localization of a target using in vivo markers
US7524274B2 (en) * 2003-11-07 2009-04-28 Cytyc Corporation Tissue positioning systems and methods for use with radiation therapy
AU2004289287A1 (en) 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
JP2007513650A (ja) 2003-11-20 2007-05-31 アンジオテック インターナショナル アーゲー 移植可能なセンサーおよび移植可能なポンプならびに瘢痕化抑制剤
US20050234336A1 (en) * 2004-03-26 2005-10-20 Beckman Andrew T Apparatus and method for marking tissue
US20080177179A1 (en) * 2006-12-19 2008-07-24 Cytyc Corporation Target Tissue Locator for Image Guided Radiotherapy
US20090024225A1 (en) 2007-07-16 2009-01-22 Stubbs James B Implant for Targeting Therapeutic Procedure

Also Published As

Publication number Publication date
AU2009241851A1 (en) 2009-11-05
US8680498B2 (en) 2014-03-25
BRPI0911904A2 (pt) 2019-03-06
KR20110009175A (ko) 2011-01-27
US20160250018A1 (en) 2016-09-01
CN102119046B (zh) 2016-10-26
WO2009134340A1 (en) 2009-11-05
CN102119046A (zh) 2011-07-06
US20140156003A1 (en) 2014-06-05
BRPI0911904B1 (pt) 2020-12-08
US20080281388A1 (en) 2008-11-13
US20120302818A1 (en) 2012-11-29
KR20160050093A (ko) 2016-05-10
US20140012376A1 (en) 2014-01-09
EP2271404A1 (en) 2011-01-12
AU2009241851B2 (en) 2014-04-03
CA2722747A1 (en) 2009-11-05
CA2722747C (en) 2020-07-07
US8541764B2 (en) 2013-09-24
US8288745B2 (en) 2012-10-16
JP2011518640A (ja) 2011-06-30

Similar Documents

Publication Publication Date Title
BRPI0911904B8 (pt) sistema de radiaçao parcial da mama e material biocompativel e biodegradavel para uso em metodo de radiaçao parcial da mama
BR112012017259A2 (pt) sistema de fusão e fixação de articulação sacroilíaca
ECSP12012097A (es) Derivados de fumarato de ácido graso y sus usos
BR102018001658B8 (pt) Elemento e sistema de fixação para introdução no canal do dente e uso do elemento de fixação para introdução no canal do dente
BR112012018132A2 (pt) "marcadores de células - tronco tumorais e uso dos mesmos".
BR112012007747A2 (pt) Compostos heterocíclicos úteis como inibidores de pdk1, sua composição farmacêutica e seus usos
BRPI0821007A2 (pt) Sistemas para rastrear um instrumento médioco durante um procedimento intervencional e para minimizar a dose de radiação durante supervisão de um istrumento médico, e, método para rastrear um instrumento médico
BRPI0917920B8 (pt) expansão direcional de dispositivos intraluminais
BR112012004377A2 (pt) terapia de reposição enzimática com progressão de dose para tratamento de deficiência de esfingomielinase ácida.
BR112012019537A2 (pt) dispositivo para o tratamento do canal vaginal e equipamento relevante
BRPI0914950A2 (pt) implantes, sistemas e técnicas de aumento da vantagem mecânica de parafusos ósseos
BRPI1014971A2 (pt) sistema de distribuição de implantes.
ECSP11011139A (es) Anticuerpos contra la angiopoyetina 2 humana
MX343363B (es) Metodos para recelularizar un tejido o un organo para una transplantabilidad mejorada.
BRPI0918093A2 (pt) sistema de implante para estabilização de ossos
BRPI0609393B8 (pt) usos de um composto 11-desóxi-prostaglandina
AR079160A1 (es) Composicion farmaceutica que comprende una sal de estroncio, vitamina d y una ciclodextrina
BR112012010249A2 (pt) esterilização de hidrógeis biodegradáveis
GT200900201A (es) Formulaciones para el tratamiento del cáncer.
BR112012030791A2 (pt) implantes ortopédicos
BR112012028880A2 (pt) mascára de sono configurada para prover terapia de luz a um individuo, método de geração de radiação eletromagnética em uma primeira faixa de comprimento de onda e uma segunda faixa de comprimento de onda para liberar a um individuo e sistema configurado para prover a terapia de luz a um individuo.
BR112013009294A2 (pt) componente dental, fixação dental, conjunto de implante dental e sistema de implante dental
BR112014029349A2 (pt) métodos, sistemas e dispositivos para administração de fármacos e oclusão vascular
BR112015003806A2 (pt) implante ósseo
BRPI0709769B8 (pt) implantes biodegradáveis para o tratamento de estados associados à dopamina

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 08/12/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/04/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO