BRPI0908398A2 - Uso de lucantona e antimetabólito em combinação, bm como composição e kit farmacêuticos - Google Patents

Uso de lucantona e antimetabólito em combinação, bm como composição e kit farmacêuticos

Info

Publication number
BRPI0908398A2
BRPI0908398A2 BRPI0908398-7A BRPI0908398A BRPI0908398A2 BR PI0908398 A2 BRPI0908398 A2 BR PI0908398A2 BR PI0908398 A BRPI0908398 A BR PI0908398A BR PI0908398 A2 BRPI0908398 A2 BR PI0908398A2
Authority
BR
Brazil
Prior art keywords
lucantone
antimetabolite
kit
combination
pharmaceutical composition
Prior art date
Application number
BRPI0908398-7A
Other languages
English (en)
Portuguese (pt)
Inventor
Guru Reddy
Luigi Lenaz
Original Assignee
Spectrum Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spectrum Pharmaceuticals Inc filed Critical Spectrum Pharmaceuticals Inc
Publication of BRPI0908398A2 publication Critical patent/BRPI0908398A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
BRPI0908398-7A 2008-02-29 2009-02-20 Uso de lucantona e antimetabólito em combinação, bm como composição e kit farmacêuticos BRPI0908398A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3283108P 2008-02-29 2008-02-29
PCT/US2009/034629 WO2009108573A1 (en) 2008-02-29 2009-02-20 Combination anti-cancer agents

Publications (1)

Publication Number Publication Date
BRPI0908398A2 true BRPI0908398A2 (pt) 2015-08-11

Family

ID=40566524

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0908398-7A BRPI0908398A2 (pt) 2008-02-29 2009-02-20 Uso de lucantona e antimetabólito em combinação, bm como composição e kit farmacêuticos

Country Status (13)

Country Link
US (1) US20090221615A1 (https=)
EP (1) EP2257285A1 (https=)
JP (1) JP5590560B2 (https=)
KR (1) KR20100126453A (https=)
CN (1) CN102014895A (https=)
AU (1) AU2009219464B2 (https=)
BR (1) BRPI0908398A2 (https=)
CA (1) CA2717100A1 (https=)
IL (1) IL207859A (https=)
MX (1) MX2010009502A (https=)
RU (1) RU2516027C2 (https=)
WO (1) WO2009108573A1 (https=)
ZA (1) ZA201006123B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012022243A8 (pt) 2010-03-08 2021-11-09 Spectrum Pharmaceuticals Inc Uso de um inibidor de autofagia baseado em tioxantona e de um composto indutor de autofagia para terapia de câncer, composição farmacêutica e kit farmacêutico
EP2425830A1 (en) 2010-09-03 2012-03-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Synergistic drug combination for the treatment of cancer
WO2023114245A2 (en) * 2021-12-14 2023-06-22 Radin Daniel Pierce Compositions and methods for treating cancers of the central nervous system (cns), including glioblastoma and chemoresistant cns tumors, and related compositions and methods for inhibiting and eliminating cns cancer stem cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL135258A0 (en) * 1997-09-26 2001-05-20 Noven Pharma Bioadhesive compositions and methods for topical administration of active agents
US6391911B1 (en) * 1999-02-26 2002-05-21 Robert E. Bases Coadministration of lucanthone and radiation for treatment of cancer
WO2007071958A2 (en) * 2005-12-22 2007-06-28 Astrazeneca Ab Combination of zd6474 and pemetrexed
ATE502641T1 (de) * 2005-12-22 2011-04-15 Astrazeneca Ab Kombination aus azd2171 und pemetrexed

Also Published As

Publication number Publication date
EP2257285A1 (en) 2010-12-08
MX2010009502A (es) 2010-11-10
IL207859A (en) 2015-09-24
AU2009219464A1 (en) 2009-09-03
RU2516027C2 (ru) 2014-05-20
CA2717100A1 (en) 2009-09-03
RU2010139840A (ru) 2012-04-10
AU2009219464B2 (en) 2015-04-09
ZA201006123B (en) 2011-05-25
JP5590560B2 (ja) 2014-09-17
KR20100126453A (ko) 2010-12-01
WO2009108573A1 (en) 2009-09-03
US20090221615A1 (en) 2009-09-03
JP2011513315A (ja) 2011-04-28
IL207859A0 (en) 2010-12-30
CN102014895A (zh) 2011-04-13

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]