BRPI0905073A2 - Depósito implantável de drogas para reduzir, prevenir ou tratar dor em um paciente em necessidade de tal tratamento e método para tratar dor aguda. - Google Patents

Depósito implantável de drogas para reduzir, prevenir ou tratar dor em um paciente em necessidade de tal tratamento e método para tratar dor aguda.

Info

Publication number
BRPI0905073A2
BRPI0905073A2 BRPI0905073-6A BRPI0905073A BRPI0905073A2 BR PI0905073 A2 BRPI0905073 A2 BR PI0905073A2 BR PI0905073 A BRPI0905073 A BR PI0905073A BR PI0905073 A2 BRPI0905073 A2 BR PI0905073A2
Authority
BR
Brazil
Prior art keywords
pain
patient
treatment
prevent
reduce
Prior art date
Application number
BRPI0905073-6A
Other languages
English (en)
Inventor
John Myers Zanella
Vanja Margareta King
Christopher M Hobot
Danielle Biggs
Katara Shaw
Philip Edward Mcdonald
William F Mckay
Kathy L Remsen
Original Assignee
Warsaw Orthopedic Inc
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warsaw Orthopedic Inc, Medtronic Inc filed Critical Warsaw Orthopedic Inc
Publication of BRPI0905073A2 publication Critical patent/BRPI0905073A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BRPI0905073-6A 2008-04-18 2009-04-17 Depósito implantável de drogas para reduzir, prevenir ou tratar dor em um paciente em necessidade de tal tratamento e método para tratar dor aguda. BRPI0905073A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4620108P 2008-04-18 2008-04-18
US12/420,197 US8946277B2 (en) 2008-04-18 2009-04-08 Clonidine formulations in a biodegradable polymer carrier
PCT/US2009/040953 WO2009129460A2 (en) 2008-04-18 2009-04-17 Clonidine formulations in a biodegradable polymer carrier

Publications (1)

Publication Number Publication Date
BRPI0905073A2 true BRPI0905073A2 (pt) 2015-07-07

Family

ID=40792647

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0905073-6A BRPI0905073A2 (pt) 2008-04-18 2009-04-17 Depósito implantável de drogas para reduzir, prevenir ou tratar dor em um paciente em necessidade de tal tratamento e método para tratar dor aguda.

Country Status (10)

Country Link
US (3) US8946277B2 (pt)
EP (1) EP2219599A2 (pt)
JP (1) JP5341172B2 (pt)
KR (1) KR101350680B1 (pt)
CN (2) CN104997722A (pt)
AU (1) AU2009236115B2 (pt)
BR (1) BRPI0905073A2 (pt)
CA (1) CA2700586C (pt)
RU (1) RU2494731C2 (pt)
WO (1) WO2009129460A2 (pt)

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US8629172B2 (en) * 2008-04-18 2014-01-14 Warsaw Orthopedic, Inc. Methods and compositions for treating post-operative pain comprising clonidine
USRE48948E1 (en) 2008-04-18 2022-03-01 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable polymer
US20100239632A1 (en) 2009-03-23 2010-09-23 Warsaw Orthopedic, Inc. Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue
US20110027331A1 (en) * 2009-07-29 2011-02-03 Warsaw Orthopedic, Inc. An implantable drug depot having a reversible phase transition material for treatment of pain and/or inflammation
US20110097375A1 (en) * 2009-10-26 2011-04-28 Warsaw Orthopedic, Inc. Formulation for preventing or reducing bleeding at a surgical site
US8221428B2 (en) 2010-01-26 2012-07-17 Warsaw Orthopedic, Inc. Sacro-iliac joint implant system, method and instrument
US20110184520A1 (en) * 2010-01-27 2011-07-28 Warsaw Orthopedic, Inc. Sacro-iliac joint implant, method and apparatus
US8945224B2 (en) * 2010-03-18 2015-02-03 Warsaw, Orthopedic, Inc. Sacro-iliac implant system, method and apparatus
US20110238181A1 (en) * 2010-03-29 2011-09-29 Warsaw Orthopedic, Inc., A Indiana Corporation Sacro-iliac joint implant system and method
US8623409B1 (en) 2010-10-20 2014-01-07 Tris Pharma Inc. Clonidine formulation
US20120142747A1 (en) * 2010-12-03 2012-06-07 Warsaw Orthopedic, Inc. Compositions and methods for delivering clonidine to a target tissue site
WO2012075443A2 (en) * 2010-12-03 2012-06-07 Warsaw Orthopedic, Inc. Methods for delivering clonidine compositions in a biodegradable polymer carrier and local steriods to a target tissue site
US9039765B2 (en) 2011-01-21 2015-05-26 Warsaw Orhtopedic, Inc. Implant system and method for stabilization of a sacro-iliac joint
US8980298B2 (en) 2011-10-24 2015-03-17 Braeburn Pharmaceuticals Bvba Sprl Implantable tizanidine compositions and methods of treatment thereof
WO2013076160A1 (en) 2011-11-21 2013-05-30 Université Libre de Bruxelles Sustained release formulations useful in the treatment of diseases
WO2013076305A1 (en) * 2011-11-25 2013-05-30 Danmarks Tekniske Universitet Formulation of solid nano-sized particles in a gel-forming system
US9511018B2 (en) * 2012-04-05 2016-12-06 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable matrix
RU2506269C1 (ru) * 2012-08-03 2014-02-10 Татьяна Георгиевна Емельянова Фармацевтическая композиция, содержащая физиологически активные гептапептиды, обладающие противосудорожным, анксиолитическим, центральным противовоспалительным и анальгетическим, а также антиалкогольным действием
US9259435B2 (en) 2012-08-31 2016-02-16 W. L. Gore & Associates, Inc. Reactive oxidative species generating materials and methods of use
US9764122B2 (en) 2014-07-25 2017-09-19 Warsaw Orthopedic, Inc. Drug delivery device and methods having an occluding member
US9775978B2 (en) 2014-07-25 2017-10-03 Warsaw Orthopedic, Inc. Drug delivery device and methods having a retaining member
GB201505527D0 (en) 2015-03-31 2015-05-13 Jmedtech Pte Ltd Composition
EA036951B1 (ru) * 2015-08-03 2021-01-19 Толмар Интернэшнл Лимитед Жидкая полимерная система доставки для длительного введения лекарственных средств
US10342576B2 (en) 2015-10-14 2019-07-09 Christopher Zarembinski Integrated needle-catheter systems and methods of use
US10076650B2 (en) 2015-11-23 2018-09-18 Warsaw Orthopedic, Inc. Enhanced stylet for drug depot injector
USD802756S1 (en) 2016-06-23 2017-11-14 Warsaw Orthopedic, Inc. Drug pellet cartridge
JP6481084B2 (ja) * 2016-06-27 2019-03-13 富士フイルム株式会社 映像表示機能付き眼鏡
US10434261B2 (en) 2016-11-08 2019-10-08 Warsaw Orthopedic, Inc. Drug pellet delivery system and method
EP3570833A4 (en) 2017-01-20 2020-08-05 Warsaw Orthopedic, Inc. ANESTHETIC COMPOSITIONS AND PROCEDURES USING IMIDAZOLINE COMPOUNDS
WO2019071243A1 (en) 2017-10-06 2019-04-11 Foundry Therapeutics, Inc. IMPLANTABLE DEPOSITS FOR CONTROLLED RELEASE OF THERAPEUTIC AGENTS
US11918689B1 (en) 2020-07-28 2024-03-05 Tris Pharma Inc Liquid clonidine extended release composition
KR102464821B1 (ko) * 2022-04-13 2022-11-09 (주)인벤티지랩 목시덱틴을 포함하는 마이크로 입자 및 이를 포함하는 서방형 주사제 조성물
GB2618810A (en) 2022-05-17 2023-11-22 Novumgen Ltd Pharmaceutical composition for sublingual administration of clonidine

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Also Published As

Publication number Publication date
WO2009129460A3 (en) 2010-02-25
CA2700586A1 (en) 2009-10-22
JP2011518182A (ja) 2011-06-23
US20090264490A1 (en) 2009-10-22
CA2700586C (en) 2017-08-22
RU2494731C2 (ru) 2013-10-10
US9585872B2 (en) 2017-03-07
US8946277B2 (en) 2015-02-03
US9763917B2 (en) 2017-09-19
WO2009129460A2 (en) 2009-10-22
KR101350680B1 (ko) 2014-02-10
US20150148396A1 (en) 2015-05-28
US20150148397A1 (en) 2015-05-28
RU2010111357A (ru) 2012-05-27
JP5341172B2 (ja) 2013-11-13
CN104997722A (zh) 2015-10-28
KR20100055512A (ko) 2010-05-26
AU2009236115B2 (en) 2015-05-21
CN101835466A (zh) 2010-09-15
WO2009129460A4 (en) 2010-04-15
AU2009236115A1 (en) 2009-10-22
EP2219599A2 (en) 2010-08-25

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