BRPI0816317A2 - Método para tratar o estresse oxidativo e melhorar a memória de trabalho pela administração de pterostilbeno - Google Patents

Método para tratar o estresse oxidativo e melhorar a memória de trabalho pela administração de pterostilbeno

Info

Publication number
BRPI0816317A2
BRPI0816317A2 BRPI0816317A BRPI0816317A BRPI0816317A2 BR PI0816317 A2 BRPI0816317 A2 BR PI0816317A2 BR PI0816317 A BRPI0816317 A BR PI0816317A BR PI0816317 A BRPI0816317 A BR PI0816317A BR PI0816317 A2 BRPI0816317 A2 BR PI0816317A2
Authority
BR
Brazil
Prior art keywords
pterostilbene
working memory
oxidative stress
subject
improve working
Prior art date
Application number
BRPI0816317A
Other languages
English (en)
Inventor
A Joseph James
M Rimando Agnes
Shukitt-Hale Barbara
Original Assignee
Us Agriculture
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Agriculture filed Critical Us Agriculture
Publication of BRPI0816317A2 publication Critical patent/BRPI0816317A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

MÉTODO PARA TRATAR O ESTRESSE OXIDATIVO E MELHORAR A MEMÓRIA DE TRABALHO PELA ADMINISTRAÇÃO DE PTEROSTILBENO. É revelada uma composição farmacêutica para tratar estresse oxidativo compreendendo uma quantidade terapeuticamente eficaz de um composto substancialmente puro de pterostilbeno e um carreador fisiologicamente aceitável. O pterostilbeno é administrado em uma quantidade entre aproximadamente 2,5 mg a aproximadamente 10 mg por quilograma de peso corporal do indivíduo. É revelado também um método para aumentar a memória de trabalho de um indivíduo, o método compreendendo a administração de uma quantidade eficaz de um composto substancialmente puro de pterostilbeno, no qual a memória de trabalho para um indivíduo aumenta e a eficácia terapêutica é de aproximadamente 10 mg de pterostilbeno por quilograma de peso corporal do indivíduo.
BRPI0816317A 2007-09-07 2008-09-04 Método para tratar o estresse oxidativo e melhorar a memória de trabalho pela administração de pterostilbeno BRPI0816317A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97059107P 2007-09-07 2007-09-07
US12/136,341 US20090069444A1 (en) 2007-09-07 2008-06-10 Method to Ameliorate Oxidative Stress and Improve Working Memory Via Pterostilbene Administration
PCT/US2008/075170 WO2009032870A2 (en) 2007-09-07 2008-09-04 Method to ameliorate oxidative stress and improve working memory via pterostilbene administration

Publications (1)

Publication Number Publication Date
BRPI0816317A2 true BRPI0816317A2 (pt) 2017-07-25

Family

ID=40429677

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0816317A BRPI0816317A2 (pt) 2007-09-07 2008-09-04 Método para tratar o estresse oxidativo e melhorar a memória de trabalho pela administração de pterostilbeno

Country Status (11)

Country Link
US (3) US20090069444A1 (pt)
EP (1) EP2200597B1 (pt)
JP (1) JP5608082B2 (pt)
KR (1) KR20100075468A (pt)
CN (2) CN101820869B (pt)
AU (1) AU2008296293A1 (pt)
BR (1) BRPI0816317A2 (pt)
CA (1) CA2698661C (pt)
ES (1) ES2526648T3 (pt)
HK (2) HK1148932A1 (pt)
WO (1) WO2009032870A2 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090069444A1 (en) * 2007-09-07 2009-03-12 The United States Of America, As Represented By Th E Secretary Of Agriculture Method to Ameliorate Oxidative Stress and Improve Working Memory Via Pterostilbene Administration
EP2445488B1 (en) * 2009-06-22 2020-03-18 Indus Biotech Private Limited Process for obtaining purified pterostilbene and methods of use thereof
US20100119499A1 (en) * 2009-09-17 2010-05-13 Kneller Bruce W Stilbene-based compositions and methods of use therefor
US20110280850A1 (en) * 2010-05-12 2011-11-17 Starr Elizabeth I Compositions Containing DNA Repair Enzyme And Anogeissus Extract
US20120237494A1 (en) * 2010-09-30 2012-09-20 Daly Susan M Compositions Containing Zinc PCA And Anogeissus Extract
EP2537513A3 (en) * 2011-03-11 2015-04-29 ELC Management LLC Use of anogeissus extract for fibrillin production in skin
US9439875B2 (en) * 2011-05-11 2016-09-13 The United States Of America, As Represented By The Secretary Of Agriculture Anxiolytic effect of pterostilbene
US20130072509A1 (en) * 2011-09-15 2013-03-21 ChromaDex Inc. Pterostilbene and statin combination for treatment of metabolic disease, cardiovascular disease, and inflammation
WO2013051459A1 (ja) * 2011-10-02 2013-04-11 キユーピー 株式会社 ＲＮＡ干渉によるｍＲＮＡ発現の抑制を促進する促進剤およびその用途
JP5901547B2 (ja) 2012-03-28 2016-04-13 富士フイルム株式会社 組成物、これを含む皮膚外用剤、又は機能性食品
KR20160067195A (ko) 2013-10-30 2016-06-13 크로마덱스 아이엔씨. 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물
JP7132907B2 (ja) 2016-08-22 2022-09-07 エリジウム・ヘルス・インコーポレイテッド ニコチンアミドリボシド及びプテロスチルベン組成物及び神経変性障害の治療方法
WO2018089830A1 (en) 2016-11-11 2018-05-17 The Queen's University Of Belfast Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof
US11071747B2 (en) 2016-11-29 2021-07-27 University Of Iowa Research Foundation Use of NAD precursors for breast enhancement
JP7136795B2 (ja) 2016-11-29 2022-09-13 ユニバーシティー オブ アイオワ リサーチ ファウンデーション 母体の健康および／または子の健康を向上させるためのｎａｄ前駆体の使用
BR112020023001A2 (pt) 2018-05-15 2021-02-02 Alkahest, Inc. tratamento de doença associada ao envelhecimento com moduladores da leucotrieno a4 hidrolase
JP7345312B2 (ja) * 2019-08-09 2023-09-15 キユーピー株式会社 発酵乳
CN112618520A (zh) * 2021-01-14 2021-04-09 姚大纯 紫檀芪或白藜芦醇在制备用于治疗或改善孤独症谱系障碍的药物中的应用
AU2022376563A1 (en) 2021-11-01 2023-12-07 Alkahest, Inc. Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050038125A1 (en) * 2003-08-15 2005-02-17 Smit Hobbe Friso Method for the treatment of arthritis and pain
JP4633572B2 (ja) * 2004-07-30 2011-02-16 イスクラ産業株式会社 糖尿病改善剤
US20060057231A1 (en) * 2004-08-19 2006-03-16 Rimando Agnes M Pterostilbene as a new agonist for the peroxisome proliferator-activated receptor alpha isoform
US20090069444A1 (en) * 2007-09-07 2009-03-12 The United States Of America, As Represented By Th E Secretary Of Agriculture Method to Ameliorate Oxidative Stress and Improve Working Memory Via Pterostilbene Administration

Also Published As

Publication number Publication date
WO2009032870A3 (en) 2009-05-22
HK1148932A1 (en) 2011-09-23
EP2200597B1 (en) 2014-11-12
CN101820869A (zh) 2010-09-01
US20140256827A1 (en) 2014-09-11
KR20100075468A (ko) 2010-07-02
CA2698661C (en) 2016-03-29
AU2008296293A1 (en) 2009-03-12
JP2010538077A (ja) 2010-12-09
CA2698661A1 (en) 2009-03-12
US20120035272A1 (en) 2012-02-09
CN101820869B (zh) 2012-12-12
JP5608082B2 (ja) 2014-10-15
US8809400B2 (en) 2014-08-19
WO2009032870A2 (en) 2009-03-12
US20090069444A1 (en) 2009-03-12
US9028887B2 (en) 2015-05-12
ES2526648T3 (es) 2015-01-14
HK1185257A1 (zh) 2014-02-14
CN103083288A (zh) 2013-05-08
EP2200597A4 (en) 2010-09-08
EP2200597A2 (en) 2010-06-30
CN103083288B (zh) 2016-04-13

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]