BRPI0814177A2 - Derivados de 1-oxo-1,2-di-hidroisoquinoleína-5-carboxamidas e de 4-oxo-3,4-di-hidroquinazolina-8-carboxamidas, sua preparação e sua aplicação em terapêutica - Google Patents
Derivados de 1-oxo-1,2-di-hidroisoquinoleína-5-carboxamidas e de 4-oxo-3,4-di-hidroquinazolina-8-carboxamidas, sua preparação e sua aplicação em terapêuticaInfo
- Publication number
- BRPI0814177A2 BRPI0814177A2 BRPI0814177-0A2A BRPI0814177A BRPI0814177A2 BR PI0814177 A2 BRPI0814177 A2 BR PI0814177A2 BR PI0814177 A BRPI0814177 A BR PI0814177A BR PI0814177 A2 BRPI0814177 A2 BR PI0814177A2
- Authority
- BR
- Brazil
- Prior art keywords
- oxo
- hydroisoquinolein
- hydroquinazoline
- carboxamides
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0705500A FR2919286A1 (fr) | 2007-07-27 | 2007-07-27 | Derives de derives de 1-oxo-1,2-dihydroisoquinoleine-5- carboxamides et de 4-oxo-3,4-dihydroquinazoline-8- carboxamides,leur preparation et leur application en therapeutique. |
PCT/FR2008/001109 WO2009044018A2 (fr) | 2007-07-27 | 2008-07-25 | Dérivés de 1-0x0-1,2-dihydroisoquinoleine-5-carboxamides et de 4-oxo-3,4-dihydroquinazoline-8-carboxamides, leur préparation et leur application en thérapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0814177A2 true BRPI0814177A2 (pt) | 2015-01-20 |
Family
ID=39106736
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0814177-0A2A BRPI0814177A2 (pt) | 2007-07-27 | 2008-07-25 | Derivados de 1-oxo-1,2-di-hidroisoquinoleína-5-carboxamidas e de 4-oxo-3,4-di-hidroquinazolina-8-carboxamidas, sua preparação e sua aplicação em terapêutica |
Country Status (16)
Country | Link |
---|---|
US (1) | US8030320B2 (pt) |
EP (1) | EP2185523A2 (pt) |
JP (1) | JP2010534640A (pt) |
KR (1) | KR20100047294A (pt) |
CN (1) | CN101790518A (pt) |
AU (1) | AU2008306762A1 (pt) |
BR (1) | BRPI0814177A2 (pt) |
CA (1) | CA2694313A1 (pt) |
CO (1) | CO6290668A2 (pt) |
EA (1) | EA201070196A1 (pt) |
FR (1) | FR2919286A1 (pt) |
MA (1) | MA31629B1 (pt) |
MX (1) | MX2010001081A (pt) |
NZ (1) | NZ582995A (pt) |
WO (1) | WO2009044018A2 (pt) |
ZA (1) | ZA201000583B (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2687750C (en) * | 2007-07-06 | 2016-10-18 | Boehringer Ingelheim International Gmbh | Substituted amino-quinazolinones, medicaments comprising said compound, their use and their method of manufacture |
FR2919285B1 (fr) * | 2007-07-27 | 2012-08-31 | Sanofi Aventis | Derives de 1-oxo-isoindoline-4-carboxamides et de 1-oxo- 1,2,3,4-tetrahydroisoquinoleine-5-carboxamides, leur preparation et leur application en therapeutique. |
MX346147B (es) | 2012-03-07 | 2017-03-09 | Inst Of Cancer Research: Royal Cancer Hospital (The) | Compuestos de 3-aril-5-substituido-isoquinolin-1-ona y su uso terapeutico. |
CN103087047B (zh) * | 2012-12-10 | 2016-12-21 | 南京农业大学 | 一种含二氢异喹啉基团的吡咯烷‑2,4‑二酮类化合物、制备方法及其应用 |
CA2922469A1 (en) | 2013-09-11 | 2015-03-19 | Institute Of Cancer Research: Royal Cancer Hospital (The) | 3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use |
CN115397824A (zh) * | 2020-04-02 | 2022-11-25 | 吉利德科学公司 | 用于制备cot抑制剂化合物的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS50504A (en) * | 2001-11-08 | 2007-04-10 | Elan Pharmaceuticals Inc., | N,n'-substituted-1,3-diamino-2- hydroxypropane derivatives |
KR20040086428A (ko) | 2002-02-22 | 2004-10-08 | 데이진 가부시키가이샤 | 피롤로피리미딘 유도체 |
GB0309221D0 (en) | 2003-04-23 | 2003-06-04 | Glaxo Group Ltd | Novel compounds |
GB0328900D0 (en) | 2003-12-12 | 2004-01-14 | Glaxo Group Ltd | Novel compounds |
US7745470B2 (en) | 2005-03-10 | 2010-06-29 | Bristol-Myers Squibb Company | Isophthalates as beta-secretase inhibitors |
GB0506562D0 (en) | 2005-03-31 | 2005-05-04 | Glaxo Group Ltd | Novel compounds |
-
2007
- 2007-07-27 FR FR0705500A patent/FR2919286A1/fr active Pending
-
2008
- 2008-07-25 AU AU2008306762A patent/AU2008306762A1/en not_active Abandoned
- 2008-07-25 CN CN200880104537A patent/CN101790518A/zh active Pending
- 2008-07-25 EA EA201070196A patent/EA201070196A1/ru unknown
- 2008-07-25 CA CA2694313A patent/CA2694313A1/fr not_active Abandoned
- 2008-07-25 MX MX2010001081A patent/MX2010001081A/es not_active Application Discontinuation
- 2008-07-25 KR KR1020107004332A patent/KR20100047294A/ko not_active Application Discontinuation
- 2008-07-25 WO PCT/FR2008/001109 patent/WO2009044018A2/fr active Application Filing
- 2008-07-25 JP JP2010517452A patent/JP2010534640A/ja not_active Withdrawn
- 2008-07-25 BR BRPI0814177-0A2A patent/BRPI0814177A2/pt not_active IP Right Cessation
- 2008-07-25 EP EP08835688A patent/EP2185523A2/fr not_active Withdrawn
- 2008-07-25 NZ NZ582995A patent/NZ582995A/en not_active IP Right Cessation
-
2010
- 2010-01-26 ZA ZA2010/00583A patent/ZA201000583B/en unknown
- 2010-01-26 US US12/693,598 patent/US8030320B2/en not_active Expired - Fee Related
- 2010-01-26 CO CO10007694A patent/CO6290668A2/es not_active Application Discontinuation
- 2010-02-24 MA MA32646A patent/MA31629B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
KR20100047294A (ko) | 2010-05-07 |
FR2919286A1 (fr) | 2009-01-30 |
WO2009044018A3 (fr) | 2009-06-18 |
WO2009044018A9 (fr) | 2010-10-14 |
US8030320B2 (en) | 2011-10-04 |
JP2010534640A (ja) | 2010-11-11 |
CO6290668A2 (es) | 2011-06-20 |
MA31629B1 (fr) | 2010-08-02 |
CA2694313A1 (fr) | 2009-04-09 |
AU2008306762A1 (en) | 2009-04-09 |
US20100197706A1 (en) | 2010-08-05 |
NZ582995A (en) | 2012-04-27 |
EA201070196A1 (ru) | 2010-08-30 |
WO2009044018A2 (fr) | 2009-04-09 |
ZA201000583B (en) | 2011-04-28 |
MX2010001081A (es) | 2010-03-24 |
CN101790518A (zh) | 2010-07-28 |
EP2185523A2 (fr) | 2010-05-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |