BRPI0813630A2 - combinações farmacêuticas compreendendo inibidor da tirosina quinase e anticorpo contra a integrina alfa 1 beta 5 (cd49e) - Google Patents
combinações farmacêuticas compreendendo inibidor da tirosina quinase e anticorpo contra a integrina alfa 1 beta 5 (cd49e)Info
- Publication number
- BRPI0813630A2 BRPI0813630A2 BRPI0813630A BRPI0813630A BRPI0813630A2 BR PI0813630 A2 BRPI0813630 A2 BR PI0813630A2 BR PI0813630 A BRPI0813630 A BR PI0813630A BR PI0813630 A BRPI0813630 A BR PI0813630A BR PI0813630 A2 BRPI0813630 A2 BR PI0813630A2
- Authority
- BR
- Brazil
- Prior art keywords
- cd49e
- integrin
- antibody
- beta
- alpha
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
- C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95232807P | 2007-07-27 | 2007-07-27 | |
PCT/US2008/071379 WO2009018226A2 (en) | 2007-07-27 | 2008-07-28 | Pharmaceutical combinations comprising a tyrosine kinase inhibitor and an antibody against integrin alpha 1 beta 5 (cd49e) |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0813630A2 true BRPI0813630A2 (pt) | 2019-09-24 |
Family
ID=40291258
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0813630A BRPI0813630A2 (pt) | 2007-07-27 | 2008-07-28 | combinações farmacêuticas compreendendo inibidor da tirosina quinase e anticorpo contra a integrina alfa 1 beta 5 (cd49e) |
Country Status (9)
Country | Link |
---|---|
US (1) | US20090041767A1 (pt) |
EP (1) | EP2193148A2 (pt) |
JP (1) | JP2010534685A (pt) |
KR (1) | KR20100040877A (pt) |
AU (1) | AU2008282331A1 (pt) |
BR (1) | BRPI0813630A2 (pt) |
CA (1) | CA2694644A1 (pt) |
MX (1) | MX2010000997A (pt) |
WO (1) | WO2009018226A2 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2255792A1 (en) * | 2009-05-20 | 2010-12-01 | Ratiopharm GmbH | Pharmaceutical compositions for N-[2-(Diethylamino)ethyl]5-[(fluoro-1,2-dihydro-2-oxo-3H-indole-3-ylidene) methyl]-2,4-dimenthyl-1H-pyrrole-3-carboxamide |
US8916574B2 (en) * | 2009-09-28 | 2014-12-23 | Qilu Pharmaceutical Co., Ltd. | 4-(substituted anilino)-quinazoline derivatives useful as tyrosine kinase inhibitors |
EP2688585B1 (en) | 2011-03-23 | 2018-09-05 | The Regents of The University of California | Methods and compositions for improving antiangiogenic therapy with anti-integrins |
IN2014DN07474A (pt) * | 2012-02-16 | 2015-04-24 | Capnia Inc | |
CN103656656A (zh) * | 2013-12-18 | 2014-03-26 | 北京科源创欣科技有限公司 | 甲苯磺酸索拉非尼药物组合物及制备方法 |
CN109311956A (zh) | 2015-08-25 | 2019-02-05 | 伊斯迪德股份公司 | 诱导组织形成的化合物及其应用 |
CN109715191A (zh) * | 2015-09-17 | 2019-05-03 | 伊斯迪德股份公司 | 将赘生性细胞转化成非赘生性细胞的药物缔合物及其用途 |
CN109715190A (zh) * | 2015-09-17 | 2019-05-03 | 伊斯迪德股份公司 | 将赘生性细胞转化成非赘生性细胞的生长因子受体激动剂和黏附蛋白抑制剂的药物缔合物及其用途 |
WO2017046229A1 (en) * | 2015-09-17 | 2017-03-23 | Histide Ag | Pharmaceutical association of growth factor receptor agonist and adhesion protein inhibitor for converting a neoplastic cell into a non-neoplastic cell and uses thereof |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4704366A (en) * | 1984-06-22 | 1987-11-03 | Bio-Rad Laboratories, Inc. | Process for binding IgG to protein A |
JPS61134325A (ja) * | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US4801687A (en) * | 1986-10-27 | 1989-01-31 | Bioprobe International, Inc. | Monoclonal antibody purification process using protein A |
US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
DK0531472T3 (da) * | 1991-03-06 | 2003-12-01 | Merck Patent Gmbh | Humaniserede monoklonale antistoffer |
CA2078539C (en) * | 1991-09-18 | 2005-08-02 | Kenya Shitara | Process for producing humanized chimera antibody |
GB9125979D0 (en) * | 1991-12-06 | 1992-02-05 | Wellcome Found | Antibody |
WO1993017106A1 (en) * | 1992-02-19 | 1993-09-02 | Schering Corporation | Cloning and expression of humanized monoclonal antibodies against human interleukin-4 |
US5639641A (en) * | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
DE69333209T2 (de) * | 1992-10-29 | 2004-07-01 | The Australian National University, Acton | Angiogenese-inhibierende antikörper |
US5536814A (en) * | 1993-09-27 | 1996-07-16 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
US5705154A (en) * | 1995-03-08 | 1998-01-06 | Schering Corporation | Humanized monoclonal antibodies against human interleukin-4 |
US5922676A (en) * | 1996-09-20 | 1999-07-13 | The Burnham Institute | Methods of inhibiting cancer by using superfibronectin |
US5846536A (en) * | 1996-10-04 | 1998-12-08 | The Regents Of The University Of California | Restoration of normal phenotype in cancer cells |
US6852318B1 (en) * | 1998-05-08 | 2005-02-08 | The Regents Of The University Of California | Methods for detecting and inhibiting angiogenesis |
US20040259152A1 (en) * | 2000-02-22 | 2004-12-23 | Richard Murray | Novel methods of diagnosing and screening for modulators of tissue remodeling and treating related diseases |
US7276589B2 (en) * | 2002-11-26 | 2007-10-02 | Pdl Biopharma, Inc. | Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis |
EP1575516B1 (en) * | 2002-11-26 | 2012-05-30 | Abbott Biotherapeutics Corp. | Chimeric and humanized antibodies to alpha5 beta1 integrin that modulate angiogenesis |
JP2007524605A (ja) * | 2003-04-03 | 2007-08-30 | ピーディーエル バイオファーマ,インコーポレイティド | インテグリンα5β1のインヒビターおよび組織顆粒化の制御のためのそれらの使用 |
DK1755659T3 (da) * | 2004-03-24 | 2012-02-27 | Abbott Biotherapeutics Corp | Anvendelse af anti-alfa5beta1-antistoffer til inhibering af kræftcelleproliferation |
WO2007109571A2 (en) * | 2006-03-17 | 2007-09-27 | Prometheus Laboratories, Inc. | Methods of predicting and monitoring tyrosine kinase inhibitor therapy |
PT1989231E (pt) * | 2006-03-21 | 2015-09-18 | Genentech Inc | Terapêutica combinatória que envolve antagonistas alfa5beta1 |
AU2007245164A1 (en) * | 2006-03-28 | 2007-11-08 | Biogen Idec Ma Inc. | Anti-IGF-IR antibodies and uses thereof |
-
2008
- 2008-07-28 CA CA2694644A patent/CA2694644A1/en not_active Abandoned
- 2008-07-28 US US12/181,201 patent/US20090041767A1/en not_active Abandoned
- 2008-07-28 MX MX2010000997A patent/MX2010000997A/es not_active Application Discontinuation
- 2008-07-28 KR KR1020107001803A patent/KR20100040877A/ko not_active Application Discontinuation
- 2008-07-28 BR BRPI0813630A patent/BRPI0813630A2/pt not_active IP Right Cessation
- 2008-07-28 WO PCT/US2008/071379 patent/WO2009018226A2/en active Application Filing
- 2008-07-28 JP JP2010518437A patent/JP2010534685A/ja not_active Withdrawn
- 2008-07-28 AU AU2008282331A patent/AU2008282331A1/en not_active Abandoned
- 2008-07-28 EP EP08782456A patent/EP2193148A2/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
MX2010000997A (es) | 2010-03-31 |
US20090041767A1 (en) | 2009-02-12 |
JP2010534685A (ja) | 2010-11-11 |
WO2009018226A2 (en) | 2009-02-05 |
CA2694644A1 (en) | 2009-02-05 |
KR20100040877A (ko) | 2010-04-21 |
WO2009018226A3 (en) | 2009-04-02 |
AU2008282331A1 (en) | 2009-02-05 |
EP2193148A2 (en) | 2010-06-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |