BRPI0812912A2 - Derivados de pirrol como antagonistas de p2y12 - Google Patents
Derivados de pirrol como antagonistas de p2y12Info
- Publication number
- BRPI0812912A2 BRPI0812912A2 BRPI0812912-6A2A BRPI0812912A BRPI0812912A2 BR PI0812912 A2 BRPI0812912 A2 BR PI0812912A2 BR PI0812912 A BRPI0812912 A BR PI0812912A BR PI0812912 A2 BRPI0812912 A2 BR PI0812912A2
- Authority
- BR
- Brazil
- Prior art keywords
- antagonists
- pirrol
- derivatives
- pirrol derivatives
- Prior art date
Links
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical class C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07290755 | 2007-06-18 | ||
| PCT/EP2008/004459 WO2008155022A1 (en) | 2007-06-18 | 2008-06-04 | Pyrrole derivatives as p2y12 antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0812912A2 true BRPI0812912A2 (pt) | 2014-12-09 |
Family
ID=39092503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0812912-6A2A BRPI0812912A2 (pt) | 2007-06-18 | 2008-06-04 | Derivados de pirrol como antagonistas de p2y12 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7910576B2 (https=) |
| EP (1) | EP2167487B1 (https=) |
| JP (1) | JP5371969B2 (https=) |
| KR (1) | KR20100020478A (https=) |
| CN (1) | CN101679358B (https=) |
| AU (1) | AU2008266515B2 (https=) |
| BR (1) | BRPI0812912A2 (https=) |
| CA (1) | CA2690243A1 (https=) |
| IL (1) | IL202758A (https=) |
| MX (1) | MX2009013431A (https=) |
| MY (1) | MY148901A (https=) |
| WO (1) | WO2008155022A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20090073231A (ko) | 2006-10-20 | 2009-07-02 | 노파르티스 아게 | ３-(１ｈ-인돌-３-일)-４-[２-(４-메틸-피페라진-１-일)-퀴나졸린-４-일]-피롤-２,５-디온의 결정 변체 |
| WO2013033178A1 (en) | 2011-08-30 | 2013-03-07 | University Of Utah Research Foundation | Methods and compositions for treating nephrogenic diabetes insipidus |
| DE102014108210A1 (de) | 2014-06-11 | 2015-12-17 | Dietrich Gulba | Rodentizid |
| CN121108187A (zh) | 2019-04-03 | 2025-12-12 | 阿里戈斯治疗公司 | 吡咯化合物 |
| EP4070658A1 (de) | 2021-04-06 | 2022-10-12 | BIORoxx GmbH | Verwendung von blutgerinnungshemmenden verbindungen als rodentizide |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3458515A (en) * | 1966-07-21 | 1969-07-29 | American Home Prod | Piperazine substituted pyrroles |
| US20020061892A1 (en) * | 2000-02-22 | 2002-05-23 | Tao Wang | Antiviral azaindole derivatives |
| US6861424B2 (en) | 2001-06-06 | 2005-03-01 | Schering Aktiengesellschaft | Platelet adenosine diphosphate receptor antagonists |
| US6956040B2 (en) * | 2001-07-16 | 2005-10-18 | Ranbaxy Laboratories Limited | Oxazolidinone piperazinyl derivatives as potential antimicrobials |
| OA12970A (en) | 2002-12-11 | 2006-10-13 | Schering Ag | 2-aminocarbonyl-quinoline compounds as platelet adenosine diphosphate receptor antagonists. |
| WO2005009971A1 (ja) | 2003-07-24 | 2005-02-03 | Astellas Pharma Inc. | キノロン誘導体又はその塩 |
| US7273881B2 (en) * | 2004-01-16 | 2007-09-25 | Bristol-Myers Squibb Company | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof |
| CN1778801A (zh) * | 2004-11-22 | 2006-05-31 | 中国农业科学院兰州畜牧与兽药研究所 | 喹诺酮7－((4－((z)－2－(2－氨基－4－噻唑基)－2－甲氧亚胺乙酰基)－1－哌嗪基)化合物及其制备方法 |
| EP1836189A1 (en) * | 2005-01-06 | 2007-09-26 | AstraZeneca AB | Novel pyridine compounds |
| JP2008094720A (ja) | 2005-01-20 | 2008-04-24 | Astellas Pharma Inc | キノロン誘導体のプロドラッグ又はその塩 |
| CA2603041A1 (en) * | 2005-03-28 | 2006-10-05 | Pharmacia & Upjohn Company Llc | 4-piperazinylthieno [2, 3-d] pyrimidine compounds as platelet aggregation inhibitors |
| KR101423483B1 (ko) * | 2005-11-03 | 2014-07-28 | 포톨라 파마슈티컬스, 인코포레이티드 | 〔４-(６-할로-７-치환된-２,４-디옥소-１,４-디히드로-２ｈ-퀴나졸린-３-일)-페닐〕-５-클로로티오펜-２-일-설포닐우레아 및 이의 형태 및 이와 관련된 방법 |
| WO2007103456A2 (en) * | 2006-03-06 | 2007-09-13 | Trimeris, Inc. | Piperazine and piperidine biaryl derivatives |
-
2008
- 2008-06-04 CN CN2008800208356A patent/CN101679358B/zh not_active Expired - Fee Related
- 2008-06-04 CA CA2690243A patent/CA2690243A1/en not_active Abandoned
- 2008-06-04 MX MX2009013431A patent/MX2009013431A/es active IP Right Grant
- 2008-06-04 KR KR1020097026371A patent/KR20100020478A/ko not_active Ceased
- 2008-06-04 BR BRPI0812912-6A2A patent/BRPI0812912A2/pt not_active IP Right Cessation
- 2008-06-04 JP JP2010512555A patent/JP5371969B2/ja not_active Expired - Fee Related
- 2008-06-04 EP EP08759015.4A patent/EP2167487B1/en not_active Withdrawn - After Issue
- 2008-06-04 WO PCT/EP2008/004459 patent/WO2008155022A1/en not_active Ceased
- 2008-06-04 AU AU2008266515A patent/AU2008266515B2/en not_active Ceased
- 2008-06-04 MY MYPI20094985A patent/MY148901A/en unknown
-
2009
- 2009-12-15 IL IL202758A patent/IL202758A/en not_active IP Right Cessation
- 2009-12-16 US US12/639,500 patent/US7910576B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101679358A (zh) | 2010-03-24 |
| AU2008266515B2 (en) | 2014-05-01 |
| US7910576B2 (en) | 2011-03-22 |
| CN101679358B (zh) | 2013-10-30 |
| KR20100020478A (ko) | 2010-02-22 |
| CA2690243A1 (en) | 2008-12-24 |
| JP5371969B2 (ja) | 2013-12-18 |
| JP2010530380A (ja) | 2010-09-09 |
| MY148901A (en) | 2013-06-14 |
| EP2167487A1 (en) | 2010-03-31 |
| IL202758A (en) | 2013-09-30 |
| AU2008266515A1 (en) | 2008-12-24 |
| WO2008155022A1 (en) | 2008-12-24 |
| MX2009013431A (es) | 2010-01-15 |
| HK1142593A1 (en) | 2010-12-10 |
| US20100226918A1 (en) | 2010-09-09 |
| IL202758A0 (en) | 2010-06-30 |
| EP2167487B1 (en) | 2015-02-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |