BRPI0811603A2 - Processo para preparar 2-(2-piridil-metil)-sulfinil-1h-benzimidazóis e compostos intermediários usados nele - Google Patents

Processo para preparar 2-(2-piridil-metil)-sulfinil-1h-benzimidazóis e compostos intermediários usados nele

Info

Publication number
BRPI0811603A2
BRPI0811603A2 BRPI0811603-2A2A BRPI0811603A BRPI0811603A2 BR PI0811603 A2 BRPI0811603 A2 BR PI0811603A2 BR PI0811603 A BRPI0811603 A BR PI0811603A BR PI0811603 A2 BRPI0811603 A2 BR PI0811603A2
Authority
BR
Brazil
Prior art keywords
benzymidazoes
sulphinyl
pyridyl
methyl
preparing
Prior art date
Application number
BRPI0811603-2A2A
Other languages
English (en)
Inventor
Francisco Eugenio Palomo Nicolau
Alfredo Pastor Del Castillo
Andres Molina Ponce
Original Assignee
Chemo Iberica Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Iberica Sa filed Critical Chemo Iberica Sa
Publication of BRPI0811603A2 publication Critical patent/BRPI0811603A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30Nitrogen atoms not forming part of a nitro radical
    • C07D235/32Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BRPI0811603-2A2A 2007-05-18 2008-05-15 Processo para preparar 2-(2-piridil-metil)-sulfinil-1h-benzimidazóis e compostos intermediários usados nele BRPI0811603A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07380144A EP1992619A1 (en) 2007-05-18 2007-05-18 Process for preparing 2-(2-pyridylmethyl)-sulfinyl-1H-benzimidazoles and the intermediate compounds used therein
PCT/EP2008/055997 WO2008142006A1 (en) 2007-05-18 2008-05-15 Process for preparing 2-(2-pyridylmethyl)-sulfinyl-1h-benzimidazoles and the intermediate compounds used therein

Publications (1)

Publication Number Publication Date
BRPI0811603A2 true BRPI0811603A2 (pt) 2014-11-04

Family

ID=39059384

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0811603-2A2A BRPI0811603A2 (pt) 2007-05-18 2008-05-15 Processo para preparar 2-(2-piridil-metil)-sulfinil-1h-benzimidazóis e compostos intermediários usados nele

Country Status (8)

Country Link
US (1) US20100210846A1 (pt)
EP (2) EP1992619A1 (pt)
JP (1) JP2010527379A (pt)
KR (1) KR20100021419A (pt)
CN (1) CN101679301A (pt)
BR (1) BRPI0811603A2 (pt)
CA (1) CA2685047A1 (pt)
WO (1) WO2008142006A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004056804A2 (en) 2002-12-19 2004-07-08 Teva Pharmaceutical Industries Ltd. Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
FR2925899B1 (fr) * 2007-12-27 2012-12-21 Sidem Pharma Sa Procede de preparation enantioselective de sulfoxydes.
CN102942523A (zh) * 2012-12-05 2013-02-27 寿光富康制药有限公司 一种奥美拉唑中间体2,3,5-三甲基吡啶-n-氧化物的制备方法
CN104098516B (zh) * 2013-04-15 2016-12-28 北大方正集团有限公司 一种用于制备埃索美拉唑或其钠盐的中间体及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20031813A1 (it) * 2003-09-23 2005-03-24 Dinamite Dipharma S P A In Forma A Bbreviata Diph Procedimento per la preparazione di pantoprazolo e suoi sali.
ES2273564B1 (es) * 2005-03-22 2008-04-01 Quimica Sintetica, S.A. Procedimiento para la preparacion de pantoprazol.

Also Published As

Publication number Publication date
CN101679301A (zh) 2010-03-24
EP1992619A1 (en) 2008-11-19
CA2685047A1 (en) 2008-11-27
WO2008142006A9 (en) 2009-09-24
EP2164832A1 (en) 2010-03-24
US20100210846A1 (en) 2010-08-19
WO2008142006A1 (en) 2008-11-27
KR20100021419A (ko) 2010-02-24
JP2010527379A (ja) 2010-08-12

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]