BRPI0806257A2 - método de tratamento, e, uso de uma composição imunoterapêutica - Google Patents
método de tratamento, e, uso de uma composição imunoterapêutica Download PDFInfo
- Publication number
- BRPI0806257A2 BRPI0806257A2 BRPI0806257-9A BRPI0806257A BRPI0806257A2 BR PI0806257 A2 BRPI0806257 A2 BR PI0806257A2 BR PI0806257 A BRPI0806257 A BR PI0806257A BR PI0806257 A2 BRPI0806257 A2 BR PI0806257A2
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- immunotherapeutic composition
- immune
- radiotherapy
- chemotherapy
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000001024 immunotherapeutic effect Effects 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- 238000002648 combination therapy Methods 0.000 abstract 1
- 238000009169 immunotherapy Methods 0.000 abstract 1
- 238000001959 radiotherapy Methods 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
- A61K39/001186—MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
- A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
MéTODO DE TRATAMENTO, E, USO DE UMA COMPOSIçãO IMUNOTERAPêUTICA. Uma terapia combinada, compreendendo uma imunoterapia com base em um antígeno de tumor ou um seu derivado imunológico e pelo menos um outro tratamento para câncer, tal como quimioterapia, radioterapia e/ou cirurgia.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0700284.3A GB0700284D0 (en) | 2007-01-08 | 2007-01-08 | Combination therapy |
PCT/EP2008/050133 WO2008084040A1 (en) | 2007-01-08 | 2008-01-08 | Use of mage a3-protein d fusion antigen in immunotherapy combined with surgery, chemotherapy or radiotherapy for the treatment of cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0806257A2 true BRPI0806257A2 (pt) | 2011-08-30 |
Family
ID=37801846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0806257-9A BRPI0806257A2 (pt) | 2007-01-08 | 2008-01-08 | método de tratamento, e, uso de uma composição imunoterapêutica |
Country Status (12)
Country | Link |
---|---|
US (1) | US20100008980A1 (pt) |
EP (1) | EP2099470A1 (pt) |
JP (1) | JP2010515670A (pt) |
KR (1) | KR20090099011A (pt) |
CN (1) | CN101578105A (pt) |
AU (1) | AU2008204526A1 (pt) |
BR (1) | BRPI0806257A2 (pt) |
CA (1) | CA2674315A1 (pt) |
EA (1) | EA200900735A1 (pt) |
GB (1) | GB0700284D0 (pt) |
MX (1) | MX2009007295A (pt) |
WO (1) | WO2008084040A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20120400A1 (es) * | 2009-05-27 | 2012-05-04 | Glaxosmithkline Biolog Sa | Contrucciones de casb7439 |
US20130031794A1 (en) | 2011-08-05 | 2013-02-07 | Duff Jr Ronald Richard | RAZOR BLADES WITH ALUMINUM MAGNESIUM BORIDE (AlMgB14)-BASED COATINGS |
RU2014122867A (ru) * | 2011-12-22 | 2016-02-20 | ГЛАКСОСМИТКЛАЙН ЭлЭлСи | Способ лечения рака иммунотерапевтическим средством, специфичным в отношении MAGEA3, совместно с ингибитором BRAF и/или ингибитором MEK |
CN111655714A (zh) * | 2017-11-08 | 2020-09-11 | 阿德瓦希斯公司 | 来自癌症相关蛋白的免疫原性异变肽及其使用方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6235525B1 (en) * | 1991-05-23 | 2001-05-22 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-3 and uses thereof |
CZ298347B6 (cs) * | 1998-02-05 | 2007-09-05 | Glaxosmithkline Biologicals S.A. | Fúzní protein z rodiny MAGE, kódová sekvence nukleové kyseliny, vektor, hostitelská bunka, vakcina a použití fúzního proteinu pro výrobu vakciny |
ATE446106T1 (de) * | 2001-11-29 | 2009-11-15 | Dandrit Biotech As | Pharmazeutische zusammensetzung zur auslösung einer immunantwort bei einem menschen oder einem tier |
CA2653402A1 (en) * | 2006-05-26 | 2007-12-06 | Glaxosmithkline Biologicals S.A. | Method |
-
2007
- 2007-01-08 GB GBGB0700284.3A patent/GB0700284D0/en not_active Ceased
-
2008
- 2008-01-08 AU AU2008204526A patent/AU2008204526A1/en not_active Abandoned
- 2008-01-08 CA CA002674315A patent/CA2674315A1/en not_active Abandoned
- 2008-01-08 BR BRPI0806257-9A patent/BRPI0806257A2/pt not_active IP Right Cessation
- 2008-01-08 EP EP08707835A patent/EP2099470A1/en not_active Ceased
- 2008-01-08 JP JP2009544419A patent/JP2010515670A/ja active Pending
- 2008-01-08 CN CNA2008800019176A patent/CN101578105A/zh active Pending
- 2008-01-08 US US12/520,882 patent/US20100008980A1/en not_active Abandoned
- 2008-01-08 MX MX2009007295A patent/MX2009007295A/es not_active Application Discontinuation
- 2008-01-08 WO PCT/EP2008/050133 patent/WO2008084040A1/en active Application Filing
- 2008-01-08 KR KR1020097016573A patent/KR20090099011A/ko not_active Application Discontinuation
- 2008-01-08 EA EA200900735A patent/EA200900735A1/ru unknown
Also Published As
Publication number | Publication date |
---|---|
WO2008084040A8 (en) | 2008-08-28 |
EP2099470A1 (en) | 2009-09-16 |
CN101578105A (zh) | 2009-11-11 |
US20100008980A1 (en) | 2010-01-14 |
EA200900735A1 (ru) | 2010-02-26 |
KR20090099011A (ko) | 2009-09-18 |
GB0700284D0 (en) | 2007-02-14 |
JP2010515670A (ja) | 2010-05-13 |
WO2008084040A1 (en) | 2008-07-17 |
MX2009007295A (es) | 2009-07-14 |
AU2008204526A1 (en) | 2008-07-17 |
CA2674315A1 (en) | 2008-07-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE A 4A ANUIDADE. |