BRPI0711278A2 - sistema de detecção de abastecimento insuficiente para um biosensor eletroquìmico - Google Patents
sistema de detecção de abastecimento insuficiente para um biosensor eletroquìmico Download PDFInfo
- Publication number
- BRPI0711278A2 BRPI0711278A2 BRPI0711278-5A BRPI0711278A BRPI0711278A2 BR PI0711278 A2 BRPI0711278 A2 BR PI0711278A2 BR PI0711278 A BRPI0711278 A BR PI0711278A BR PI0711278 A2 BRPI0711278 A2 BR PI0711278A2
- Authority
- BR
- Brazil
- Prior art keywords
- test
- excitation signal
- approximately
- probe
- pulse
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title abstract description 44
- 230000005284 excitation Effects 0.000 claims abstract description 342
- 230000004044 response Effects 0.000 claims abstract description 60
- 239000013060 biological fluid Substances 0.000 claims abstract description 49
- 238000004458 analytical method Methods 0.000 claims abstract description 44
- 238000012360 testing method Methods 0.000 claims description 669
- 239000000523 sample Substances 0.000 claims description 382
- 239000012491 analyte Substances 0.000 claims description 83
- 238000000034 method Methods 0.000 claims description 58
- 230000008859 change Effects 0.000 claims description 27
- 230000007704 transition Effects 0.000 claims description 26
- 230000007423 decrease Effects 0.000 claims description 13
- 230000003247 decreasing effect Effects 0.000 claims description 9
- 238000004891 communication Methods 0.000 claims description 8
- 230000009467 reduction Effects 0.000 description 33
- 238000006722 reduction reaction Methods 0.000 description 33
- 239000008280 blood Substances 0.000 description 18
- 210000004369 blood Anatomy 0.000 description 18
- 238000006479 redox reaction Methods 0.000 description 18
- 230000002829 reductive effect Effects 0.000 description 18
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 16
- 239000008103 glucose Substances 0.000 description 16
- 230000003287 optical effect Effects 0.000 description 16
- 239000004020 conductor Substances 0.000 description 11
- 239000000126 substance Substances 0.000 description 11
- 238000004082 amperometric method Methods 0.000 description 10
- 230000003647 oxidation Effects 0.000 description 10
- 238000007254 oxidation reaction Methods 0.000 description 10
- 241000894007 species Species 0.000 description 10
- 238000006243 chemical reaction Methods 0.000 description 9
- 239000003153 chemical reaction reagent Substances 0.000 description 9
- 238000004832 voltammetry Methods 0.000 description 9
- 108090000790 Enzymes Proteins 0.000 description 8
- 102000004190 Enzymes Human genes 0.000 description 8
- 229940088598 enzyme Drugs 0.000 description 8
- 239000007788 liquid Substances 0.000 description 7
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 6
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 6
- 238000012546 transfer Methods 0.000 description 6
- 230000004913 activation Effects 0.000 description 5
- 238000005259 measurement Methods 0.000 description 5
- 238000003869 coulometry Methods 0.000 description 4
- 238000005534 hematocrit Methods 0.000 description 4
- 210000003296 saliva Anatomy 0.000 description 4
- 210000002700 urine Anatomy 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 3
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 3
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 235000012000 cholesterol Nutrition 0.000 description 3
- 238000000840 electrochemical analysis Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 229940116269 uric acid Drugs 0.000 description 3
- 241000218691 Cupressaceae Species 0.000 description 2
- 230000002238 attenuated effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000012472 biological sample Substances 0.000 description 2
- 239000007795 chemical reaction product Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000002596 correlated effect Effects 0.000 description 2
- 238000002484 cyclic voltammetry Methods 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- 108010050375 Glucose 1-Dehydrogenase Proteins 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000002848 electrochemical method Methods 0.000 description 1
- 238000003487 electrochemical reaction Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000001208 nuclear magnetic resonance pulse sequence Methods 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000013102 re-test Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000015607 signal release Effects 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 230000002277 temperature effect Effects 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79712806P | 2006-05-03 | 2006-05-03 | |
| US60/797.128 | 2006-05-03 | ||
| PCT/US2007/068034 WO2007131036A1 (en) | 2006-05-03 | 2007-05-02 | Underfill detection system for an electrochemical biosensor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0711278A2 true BRPI0711278A2 (pt) | 2012-10-09 |
Family
ID=38457782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0711278-5A BRPI0711278A2 (pt) | 2006-05-03 | 2007-05-02 | sistema de detecção de abastecimento insuficiente para um biosensor eletroquìmico |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP2016399B1 (enExample) |
| JP (1) | JP5372744B2 (enExample) |
| CN (1) | CN101432620B (enExample) |
| BR (1) | BRPI0711278A2 (enExample) |
| CA (1) | CA2649644C (enExample) |
| ES (1) | ES2758478T3 (enExample) |
| MX (1) | MX2008013974A (enExample) |
| NO (1) | NO20085012L (enExample) |
| RU (1) | RU2441223C2 (enExample) |
| TW (1) | TWI449905B (enExample) |
| WO (1) | WO2007131036A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8529751B2 (en) | 2006-03-31 | 2013-09-10 | Lifescan, Inc. | Systems and methods for discriminating control solution from a physiological sample |
| US8603768B2 (en) | 2008-01-17 | 2013-12-10 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
| EP2299904B1 (en) | 2008-06-06 | 2019-09-11 | Intuity Medical, Inc. | Medical measurement method |
| CA3095014A1 (en) * | 2008-06-06 | 2009-12-10 | Intuity Medical, Inc. | Detection meter and mode of operation |
| US8551320B2 (en) | 2008-06-09 | 2013-10-08 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
| CN101900701B (zh) * | 2009-05-25 | 2014-07-16 | 利多(香港)有限公司 | 生物传感器 |
| DE102009048811B4 (de) * | 2009-10-08 | 2013-07-18 | Eads Deutschland Gmbh | Biosensorvorrichtung mit Selbsttesteinrichtung |
| BR112012009291A2 (pt) * | 2009-11-10 | 2016-05-31 | Bayer Healthcare Llc | sistema de reconhecimento de subenchimento para um biossensor |
| IL209760A (en) | 2009-12-11 | 2015-05-31 | Lifescan Scotland Ltd | A system and method for measuring filling is satisfactory |
| BR112012031375A2 (pt) * | 2010-06-07 | 2016-10-25 | Bayer Healthcare Llc | sistema de gerenciamento de enchimento abaixo do necessário para um biosensor |
| CA2803797A1 (en) | 2010-06-25 | 2011-12-29 | Intuity Medical, Inc. | Analyte monitoring methods and systems |
| EP2693208B1 (en) * | 2011-03-28 | 2017-10-11 | Panasonic Healthcare Holdings Co., Ltd. | Device for measuring biological sample |
| JP5903806B2 (ja) * | 2011-09-05 | 2016-04-13 | 船井電機株式会社 | 検出装置 |
| CN105190299B (zh) * | 2013-03-15 | 2018-04-20 | 豪夫迈·罗氏有限公司 | 电化学测量分析物的基于描述符的方法以及结合该方法的设备、装置和系统 |
| EP3011544A4 (en) | 2013-06-21 | 2017-02-22 | Intuity Medical, Inc. | Analyte monitoring system with audible feedback |
| CN105445341B (zh) * | 2014-09-12 | 2018-10-16 | 达尔生技股份有限公司 | 电化学的检测试片异常的检测方法 |
| EP3002582B1 (en) * | 2014-10-03 | 2017-07-05 | ARKRAY, Inc. | Measuring apparatus, detection method and measuring system |
| JP6654383B2 (ja) * | 2014-10-03 | 2020-02-26 | アークレイ株式会社 | 測定装置、検知方法、電気化学センサ及び測定システム |
| CN107296617B (zh) * | 2017-06-22 | 2019-10-25 | 四川东鼎里智信息技术有限责任公司 | 肌肉爆发力的监控方法 |
| EP3713477B1 (en) | 2017-11-21 | 2022-07-06 | MX3 Diagnostics, Inc. | Saliva testing system and method |
| CN109632918B (zh) * | 2019-01-02 | 2021-11-30 | 京东方科技集团股份有限公司 | 电化学检测模组和电化学检测方法 |
| US11701036B2 (en) | 2019-07-10 | 2023-07-18 | MX3 Diagnostics, Inc. | Saliva test strip and method |
| WO2021154846A1 (en) * | 2020-01-30 | 2021-08-05 | MX3 Diagnostics, Inc. | Biological fluid sample assessment |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5352351A (en) * | 1993-06-08 | 1994-10-04 | Boehringer Mannheim Corporation | Biosensing meter with fail/safe procedures to prevent erroneous indications |
| US6153069A (en) | 1995-02-09 | 2000-11-28 | Tall Oak Ventures | Apparatus for amperometric Diagnostic analysis |
| US5582697A (en) | 1995-03-17 | 1996-12-10 | Matsushita Electric Industrial Co., Ltd. | Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same |
| US5620579A (en) | 1995-05-05 | 1997-04-15 | Bayer Corporation | Apparatus for reduction of bias in amperometric sensors |
| RU2148U1 (ru) * | 1995-06-30 | 1996-05-16 | Александр Викторович Храмов | Индикаторная полоска для анализа состава биологических жидкостей |
| ATE227844T1 (de) | 1997-02-06 | 2002-11-15 | Therasense Inc | Kleinvolumiger sensor zur in-vitro bestimmung |
| CA2305922C (en) | 1999-08-02 | 2005-09-20 | Bayer Corporation | Improved electrochemical sensor design |
| JP2003156469A (ja) * | 2001-11-22 | 2003-05-30 | Matsushita Electric Ind Co Ltd | バイオセンサ、バイオセンサ用測定装置及び基質の定量方法 |
| EP2096437B1 (en) * | 2000-11-30 | 2014-11-19 | Panasonic Healthcare Co., Ltd. | Biosensor for quantifying substrate |
| US6797150B2 (en) * | 2001-10-10 | 2004-09-28 | Lifescan, Inc. | Determination of sample volume adequacy in biosensor devices |
| WO2003034055A1 (en) * | 2001-10-12 | 2003-04-24 | Arkray, Inc. | Concentration measuring method and concentration measuring device |
| AU2002349656A1 (en) * | 2001-11-20 | 2003-06-10 | Arkray, Inc. | Fail judging method and analyzer |
| WO2003044514A1 (en) * | 2001-11-20 | 2003-05-30 | Arkray, Inc. | Fail judging method for analysis and analyzer |
| US6964871B2 (en) * | 2002-04-25 | 2005-11-15 | Home Diagnostics, Inc. | Systems and methods for blood glucose sensing |
| US7132041B2 (en) * | 2003-02-11 | 2006-11-07 | Bayer Healthcare Llc | Methods of determining the concentration of an analyte in a fluid test sample |
| US6868350B2 (en) * | 2003-04-11 | 2005-03-15 | Therm-O-Disc, Incorporated | Method and apparatus for the detection of the response of a sensing device |
| US7597793B2 (en) * | 2003-06-20 | 2009-10-06 | Roche Operations Ltd. | System and method for analyte measurement employing maximum dosing time delay |
| JP4449431B2 (ja) * | 2003-11-19 | 2010-04-14 | パナソニック株式会社 | 基質濃度の測定方法 |
| JP4814110B2 (ja) * | 2004-02-06 | 2011-11-16 | バイエル・ヘルスケア・エルエルシー | 電気化学的バイオセンサ |
| CN2705975Y (zh) * | 2004-05-24 | 2005-06-22 | 天瀚科技股份有限公司 | 具有至少二轴转向功能的电子装置 |
-
2007
- 2007-05-02 EP EP07761747.0A patent/EP2016399B1/en active Active
- 2007-05-02 CN CN2007800155068A patent/CN101432620B/zh active Active
- 2007-05-02 RU RU2008147646/28A patent/RU2441223C2/ru active
- 2007-05-02 TW TW096115540A patent/TWI449905B/zh not_active IP Right Cessation
- 2007-05-02 BR BRPI0711278-5A patent/BRPI0711278A2/pt not_active IP Right Cessation
- 2007-05-02 EP EP19177674.9A patent/EP3553510B1/en active Active
- 2007-05-02 CA CA2649644A patent/CA2649644C/en not_active Expired - Fee Related
- 2007-05-02 MX MX2008013974A patent/MX2008013974A/es active IP Right Grant
- 2007-05-02 ES ES07761747T patent/ES2758478T3/es active Active
- 2007-05-02 WO PCT/US2007/068034 patent/WO2007131036A1/en not_active Ceased
- 2007-05-02 JP JP2009510051A patent/JP5372744B2/ja active Active
-
2008
- 2008-12-02 NO NO20085012A patent/NO20085012L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2649644C (en) | 2016-07-05 |
| WO2007131036A1 (en) | 2007-11-15 |
| JP2009535651A (ja) | 2009-10-01 |
| JP5372744B2 (ja) | 2013-12-18 |
| MX2008013974A (es) | 2008-11-14 |
| EP3553510B1 (en) | 2024-12-18 |
| EP2016399B1 (en) | 2019-08-28 |
| RU2441223C2 (ru) | 2012-01-27 |
| CN101432620A (zh) | 2009-05-13 |
| HK1133080A1 (en) | 2010-03-12 |
| EP3553510A1 (en) | 2019-10-16 |
| NO20085012L (no) | 2008-12-02 |
| TWI449905B (zh) | 2014-08-21 |
| CN101432620B (zh) | 2013-08-14 |
| CA2649644A1 (en) | 2007-11-15 |
| EP2016399A1 (en) | 2009-01-21 |
| TW200801503A (en) | 2008-01-01 |
| ES2758478T3 (es) | 2020-05-05 |
| RU2008147646A (ru) | 2010-06-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0711278A2 (pt) | sistema de detecção de abastecimento insuficiente para um biosensor eletroquìmico | |
| US10724985B2 (en) | Biosensor for determining a concentration of a biosensor using an underfill procedure | |
| TWI431273B (zh) | 生物感測器用之異常輸出偵測系統 | |
| JP2018173415A (ja) | 勾配ベース補正 | |
| BRPI0613592A2 (pt) | amperometria conectada por porta | |
| BRPI0707502A2 (pt) | determinaÇço de analito com temperatura ajustada para sistemas biosensores | |
| WO2011059670A1 (en) | Underfill recognition system for a biosensor | |
| HK1133080B (en) | Underfill detection system for an electrochemical biosensor | |
| HK1132643B (en) | Abnormal output detection system for a biosensor |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] |
Free format text: A DEPOSITANTE DESPACHO: SOLICITA-SE ESCLARECIMENTOS ACERCA DA DIVERGENCIA EXISTENTE NO NOME DO 2O INVENTOR. NO FORMULARIO DE PETICAO DE ENTRADA NA FASE NACIONAL, PROTOCOLO NO 020080138078, DATADO DE 03/11/2008, NAO CONSTA O NOME DO 2O INVENTOR, CONFORME COMPROVADO NO SITE DA OMPI (INTERNATIONAL APPLICATION STATUS REPORT E FORMULARIO IB 306). |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |