BRPI0618450A2 - método, bem como uso de pelo menos um polimorfismo, para a determinação e avaliação do risco de um sujeito desenvolver sìdrome coronariana aguda, sondas e/ou iniciadores nucleotìdicos, microarranjo de ácidos nucléicos e de anticorpos, método para a triagem de compostos, bem como para avaliação de possìvel sensibilidade de um sujeito, kit e uso de um agente capaz de modular a atividade de mmp12 - Google Patents
método, bem como uso de pelo menos um polimorfismo, para a determinação e avaliação do risco de um sujeito desenvolver sìdrome coronariana aguda, sondas e/ou iniciadores nucleotìdicos, microarranjo de ácidos nucléicos e de anticorpos, método para a triagem de compostos, bem como para avaliação de possìvel sensibilidade de um sujeito, kit e uso de um agente capaz de modular a atividade de mmp12 Download PDFInfo
- Publication number
- BRPI0618450A2 BRPI0618450A2 BRPI0618450-2A BRPI0618450A BRPI0618450A2 BR PI0618450 A2 BRPI0618450 A2 BR PI0618450A2 BR PI0618450 A BRPI0618450 A BR PI0618450A BR PI0618450 A2 BRPI0618450 A2 BR PI0618450A2
- Authority
- BR
- Brazil
- Prior art keywords
- subject
- risk
- acute coronary
- coronary syndrome
- polymorphism
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
MéTODO, BEM COMO USO DE PELO MENOS UM POLIMORFISMO, PARA A DETERMINAçãO E AVALIAçãO DO RISCO DE UM SUJEITO DESENVOLVER SìNDROME CORONARIANA AGUDA, SONDAS E/OU INICIADORES NUCLEOTìDICOS, MICROARRANJO DE áCIDOS NUCLéICOS E DE ANTICORPOS, MéTODO PARA A TRIAGEM DE COMPOSTOS, BEM COMO PARA AVALIAçãO DE POSSìVEL SENSIBILIDADE DE UM SUJEITO, KIT E USO DE UM AGENTE CAPAZ DE MODULAR A ATIVIDADE DE MMP1 2. A presente invenção refere-se a métodos para a avaliação do risco de desenvolver síndrome coronariana aguda (ACS) em fumantes e não fumantes, usando a análise de polimorfismos genéticos. A presente invenção também refere-se ao uso de polimorfismos genéticos na avaliação do risco de um sujeito desenvolver ACS. Sondas e iniciadores nucleotídicos, kits e microarranjos adequados para essa avaliação também são apresentados.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ54352005 | 2005-11-10 | ||
NZ54398505 | 2005-12-06 | ||
NZ54995106 | 2006-09-15 | ||
PCT/NZ2006/000292 WO2007055602A1 (en) | 2005-11-10 | 2006-11-10 | Methods and compositions for the assessment of cardiovascular function and disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0618450A2 true BRPI0618450A2 (pt) | 2011-08-30 |
Family
ID=38023503
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0618450-2A BRPI0618450A2 (pt) | 2005-11-10 | 2006-11-10 | método, bem como uso de pelo menos um polimorfismo, para a determinação e avaliação do risco de um sujeito desenvolver sìdrome coronariana aguda, sondas e/ou iniciadores nucleotìdicos, microarranjo de ácidos nucléicos e de anticorpos, método para a triagem de compostos, bem como para avaliação de possìvel sensibilidade de um sujeito, kit e uso de um agente capaz de modular a atividade de mmp12 |
Country Status (8)
Country | Link |
---|---|
US (1) | US20100267025A1 (pt) |
EP (1) | EP1951902A4 (pt) |
JP (1) | JP2010525788A (pt) |
KR (1) | KR20080084806A (pt) |
AU (1) | AU2006312411A1 (pt) |
BR (1) | BRPI0618450A2 (pt) |
CA (1) | CA2629388A1 (pt) |
WO (1) | WO2007055602A1 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8027791B2 (en) | 2004-06-23 | 2011-09-27 | Medtronic, Inc. | Self-improving classification system |
US8335652B2 (en) | 2004-06-23 | 2012-12-18 | Yougene Corp. | Self-improving identification method |
US20100041600A1 (en) * | 2006-06-09 | 2010-02-18 | Russel James A | Interferon gamma polymorphisms as indicators of subject outcome in critically ill subjects |
JP5656209B2 (ja) * | 2008-09-26 | 2015-01-21 | 独立行政法人産業技術総合研究所 | ウシタイレリア症の病態評価を可能とする方法 |
AU2014407088B2 (en) | 2014-09-26 | 2021-09-23 | Somalogic Operating Co., Inc. | Cardiovascular risk event prediction and uses thereof |
CA3012985A1 (en) | 2015-01-27 | 2016-08-04 | Kardiatonos, Inc. | Biomarkers of vascular disease |
WO2019122340A1 (en) * | 2017-12-22 | 2019-06-27 | Université D'aix-Marseille | In vitro method for predicting a predisposition to acute coronary syndrome |
CN111690733B (zh) * | 2020-06-22 | 2022-08-26 | 复旦大学附属中山医院 | 一种激素性股骨头坏死易感基因panel |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1766042A2 (en) * | 2004-05-21 | 2007-03-28 | Bayer HealthCare AG | Diagnostics and therapeutics for diseases associated with chymase (cma1) |
CA2608142A1 (en) * | 2005-05-10 | 2006-11-16 | Synergenz Bioscience Limited | Methods and compositions for assessment of pulmonary function and disorders |
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2006
- 2006-11-10 BR BRPI0618450-2A patent/BRPI0618450A2/pt not_active Application Discontinuation
- 2006-11-10 US US12/518,864 patent/US20100267025A1/en not_active Abandoned
- 2006-11-10 JP JP2008539956A patent/JP2010525788A/ja active Pending
- 2006-11-10 WO PCT/NZ2006/000292 patent/WO2007055602A1/en active Application Filing
- 2006-11-10 CA CA002629388A patent/CA2629388A1/en not_active Abandoned
- 2006-11-10 EP EP06824383A patent/EP1951902A4/en not_active Withdrawn
- 2006-11-10 KR KR1020087013914A patent/KR20080084806A/ko not_active Application Discontinuation
- 2006-11-10 AU AU2006312411A patent/AU2006312411A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2007055602A1 (en) | 2007-05-18 |
CA2629388A1 (en) | 2007-05-18 |
JP2010525788A (ja) | 2010-07-29 |
AU2006312411A1 (en) | 2007-05-18 |
KR20080084806A (ko) | 2008-09-19 |
EP1951902A4 (en) | 2009-12-02 |
US20100267025A1 (en) | 2010-10-21 |
EP1951902A1 (en) | 2008-08-06 |
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B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |