BRPI0614917B8 - processo para obtenção de um concentrado natural rico em hidroxitirosol natural a partir de resíduos de oliveira e subprodutos - Google Patents
processo para obtenção de um concentrado natural rico em hidroxitirosol natural a partir de resíduos de oliveira e subprodutosInfo
- Publication number
- BRPI0614917B8 BRPI0614917B8 BRPI0614917A BRPI0614917A BRPI0614917B8 BR PI0614917 B8 BRPI0614917 B8 BR PI0614917B8 BR PI0614917 A BRPI0614917 A BR PI0614917A BR PI0614917 A BRPI0614917 A BR PI0614917A BR PI0614917 B8 BRPI0614917 B8 BR PI0614917B8
- Authority
- BR
- Brazil
- Prior art keywords
- hydroxytyrosol
- natural
- rich
- obtaining
- products
- Prior art date
Links
- JUUBCHWRXWPFFH-UHFFFAOYSA-N Hydroxytyrosol Chemical compound OCCC1=CC=C(O)C(O)=C1 JUUBCHWRXWPFFH-UHFFFAOYSA-N 0.000 title abstract 14
- 229940095066 hydroxytyrosol Drugs 0.000 title abstract 7
- 235000003248 hydroxytyrosol Nutrition 0.000 title abstract 7
- 239000012141 concentrate Substances 0.000 title abstract 5
- 240000007817 Olea europaea Species 0.000 title abstract 3
- 239000006227 byproduct Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000005516 engineering process Methods 0.000 abstract 3
- 230000003217 anti-cancerogenic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000001728 nano-filtration Methods 0.000 abstract 1
- 239000002105 nanoparticle Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 238000001223 reverse osmosis Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000000194 supercritical-fluid extraction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/004—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by obtaining phenols from plant material or from animal material
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B5/00—Preserving by using additives, e.g. anti-oxidants
- C11B5/0021—Preserving by using additives, e.g. anti-oxidants containing oxygen
- C11B5/0035—Phenols; Their halogenated and aminated derivates, their salts, their esters with carboxylic acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with no unsaturation outside the aromatic ring
- C07C39/11—Alkylated hydroxy benzenes containing also acyclically bound hydroxy groups, e.g. saligenol
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
- C11B1/06—Production of fats or fatty oils from raw materials by pressing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Birds (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Emergency Medicine (AREA)
- Biotechnology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Cosmetics (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
processo para a obtenção de um concentrado natural, rico em hidroxitirosol, a partir de resíduos de oliveiras e de subprodutos, utilizando tecnologias limpas. a presente invenção refere-se a um processo para a obtenção de um concentrado natural, bioativo, rico em hidroxitirosol, a partir de resíduos de oliveiras e de subprodutos, utilizando tecnologias limpas. estas tecnologias compreendem a extração por um fluido supercrítico, a nanofiltração e a osmose inversa, que são utilizadas individualmente ou num modo integrado. o extrato natural compreende uma concentração mínima de 15% (fração mássica) de hidroxitirosol e uma concentração máxima de 98% (fração mássica) deste composto. o concentrado rico em hidroxitirosol exibe atividades antioxidante, anti- microbiana, anti-inflamatória e anticarcinogénica, que são superiores às atividades observadas para o hidroxitirosol isolado, em concentração equivalente, o concentrado rico em hidroxitirosol pode ser preparado na forma de partículas sólidas, como uma solução aquosa, em emulsão ou como nanopartículas de base lipídica. a aplicação industrial compreende as indústrias alimentar, farmacêutica e cosmética.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT103326A PT103326A (pt) | 2005-07-27 | 2005-07-27 | Método para obtenção de um concentrado natural rico em hidroxitirosol a partir de resíduos da produção de azeite utilizando tecnologias limpas |
| PT103326 | 2005-07-27 | ||
| PCT/IB2006/052552 WO2007013032A2 (en) | 2005-07-27 | 2006-07-25 | Method of obtaining a natural hydroxytyrosol-rich concentrate from olive tree residues and subproducts using clean technologies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0614917A2 BRPI0614917A2 (pt) | 2011-04-19 |
| BRPI0614917B1 BRPI0614917B1 (pt) | 2019-08-20 |
| BRPI0614917B8 true BRPI0614917B8 (pt) | 2021-05-25 |
Family
ID=37547039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0614917A BRPI0614917B8 (pt) | 2005-07-27 | 2006-07-25 | processo para obtenção de um concentrado natural rico em hidroxitirosol natural a partir de resíduos de oliveira e subprodutos |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8066881B2 (pt) |
| EP (1) | EP1910257B1 (pt) |
| AU (1) | AU2006273658A1 (pt) |
| BR (1) | BRPI0614917B8 (pt) |
| CA (1) | CA2617002C (pt) |
| ES (1) | ES2455999T3 (pt) |
| MA (1) | MA29748B1 (pt) |
| PL (1) | PL1910257T3 (pt) |
| PT (2) | PT103326A (pt) |
| TN (1) | TNSN08045A1 (pt) |
| WO (1) | WO2007013032A2 (pt) |
| ZA (1) | ZA200800880B (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1844785A1 (en) | 2006-04-13 | 2007-10-17 | Indena S.P.A. | Phospholipid complexes of olive fruits or leaves extracts having improved bioavailability |
| EP1922933A1 (de) * | 2006-11-14 | 2008-05-21 | DSMIP Assets B.V. | Nahrungsmittel enthaltend einen Olivenextrakt |
| MX2010000832A (es) | 2007-07-23 | 2010-07-06 | Probelte Pharma S A | Enriquecimiento de productos nutricionales con extractos de oliva conteniendo hidroxitirosol y productos nutricionales enriquecidos con hidroxitirosol. |
| EP2178397A1 (en) * | 2007-08-21 | 2010-04-28 | DSM IP Assets B.V. | Methods of making olive juice extracts containing reduced solids |
| FR2942224B1 (fr) | 2009-02-18 | 2012-11-30 | Centre De Cooperation Internationale En Rech Agronomique Pour Le Developpement Cirad | Procede d'extraction de composes phenoliques a partir d'eau de vegetation de l'olive et preparation d'extrait titre en polyphenols d'olive et de raisin |
| EP2277388A1 (en) * | 2009-07-23 | 2011-01-26 | Alsecco International | Solid alpechin product and process for preparing a solid alpechin product |
| ITMI20110941A1 (it) | 2011-05-25 | 2012-11-26 | Phenofarm S R L | Processo di produzione di un fito-estratto da acque di vegetazione esanse olearie |
| US9420820B2 (en) * | 2013-08-09 | 2016-08-23 | University Of Tsukuba | Method for isolating polyphenols from olive mill water |
| US20150101987A1 (en) * | 2013-10-12 | 2015-04-16 | Synder Filtration | Stacked plate-shaped composite membrane cartridge |
| FR3018686B1 (fr) | 2014-03-24 | 2017-05-19 | Pierre Fabre Dermo-Cosmetique | Utilisation cosmetique d'un extrait de margines d'olivier pour redensifier le cheveu |
| US10532022B2 (en) * | 2014-07-21 | 2020-01-14 | The United States Of America, As Represented By The Secretary Of Agriculture | Whole stablized olive mill process water, production thereof and uses thereof |
| US10155176B1 (en) | 2016-11-03 | 2018-12-18 | Healer, LLC | Process for the production of a concentrated cannabinoid product |
| IT201800005151A1 (it) * | 2018-05-08 | 2019-11-08 | Estratto di acque di vegetazione per uso nel trattamento e/o nella prevenzione del cancro prostatico | |
| EP3818837B1 (en) | 2019-11-07 | 2023-08-30 | Michel Rumiz | Method for reducing the concentration of oleuropein and for formation and preservation of the concentration of hydroxytyrosol and tyrosol in olives |
| ES2851098A1 (es) * | 2020-03-02 | 2021-09-03 | Fundacion Centro Gallego De Investig Del Agua | Un procedimiento y sistema para la recuperación de polifenoles a partir de residuos sólidos o de residuos sólidos y residuos líquidos industriales del sector de alimentación y bebidas |
| IT202100009482A1 (it) * | 2021-04-15 | 2022-10-15 | Fattoria La Vialla Di Gianni Antonio E Bandino Lo Franco Soc Agricola Semplice | Processo di frazionamento |
| PT118300A (pt) | 2022-10-31 | 2024-04-30 | Silva Pinto Agro Lda | Processo de produção de azeite com elevado teor de antioxidantes e de um concentrado de antioxidantes |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1204691B (it) * | 1987-06-05 | 1989-03-10 | Snia Fibre | Procedimento per il trattamento degli effluenti della industria frantoiana |
| US7713569B2 (en) * | 2000-09-01 | 2010-05-11 | Creagri, Inc. | Hydroxytyrosol-rich composition from olive vegetation water and method of use thereof |
| EP1315691B2 (en) * | 2000-09-01 | 2017-09-13 | Creagri, Inc. | Method of obtaining a hydroxytyrosol-rich composition from vegetation water |
| ITMI20041627A1 (it) * | 2004-08-06 | 2004-11-06 | Lachifarma S R L Lab Chimi Co | Processo per il recupero di tirosolo idrossitirosolo e altri componenti fenolici da acque di vegetazione e metodo di ossidazione catalitica di tirosolo a idrossitirosolo |
-
2005
- 2005-07-27 PT PT103326A patent/PT103326A/pt not_active IP Right Cessation
-
2006
- 2006-07-25 ES ES06780204.1T patent/ES2455999T3/es active Active
- 2006-07-25 PT PT67802041T patent/PT1910257E/pt unknown
- 2006-07-25 AU AU2006273658A patent/AU2006273658A1/en not_active Abandoned
- 2006-07-25 PL PL06780204T patent/PL1910257T3/pl unknown
- 2006-07-25 BR BRPI0614917A patent/BRPI0614917B8/pt active IP Right Grant
- 2006-07-25 EP EP06780204.1A patent/EP1910257B1/en active Active
- 2006-07-25 WO PCT/IB2006/052552 patent/WO2007013032A2/en active Application Filing
- 2006-07-25 CA CA2617002A patent/CA2617002C/en not_active Expired - Fee Related
-
2008
- 2008-01-28 TN TNP2008000045A patent/TNSN08045A1/en unknown
- 2008-01-28 US US12/020,960 patent/US8066881B2/en active Active
- 2008-01-29 ZA ZA200800880A patent/ZA200800880B/xx unknown
- 2008-02-22 MA MA30673A patent/MA29748B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MA29748B1 (fr) | 2008-09-01 |
| BRPI0614917A2 (pt) | 2011-04-19 |
| ES2455999T3 (es) | 2014-04-21 |
| EP1910257B1 (en) | 2014-01-01 |
| US8066881B2 (en) | 2011-11-29 |
| AU2006273658A2 (en) | 2008-04-03 |
| WO2007013032A2 (en) | 2007-02-01 |
| AU2006273658A1 (en) | 2007-02-01 |
| BRPI0614917B1 (pt) | 2019-08-20 |
| ZA200800880B (en) | 2009-01-28 |
| US20080179246A1 (en) | 2008-07-31 |
| CA2617002C (en) | 2014-02-11 |
| PL1910257T3 (pl) | 2014-07-31 |
| EP1910257A2 (en) | 2008-04-16 |
| PT103326A (pt) | 2007-01-31 |
| PT1910257E (pt) | 2014-04-10 |
| WO2007013032A3 (en) | 2007-05-31 |
| TNSN08045A1 (en) | 2009-07-14 |
| CA2617002A1 (en) | 2007-02-01 |
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