BRPI0613307B8 - processos de fabricação de um composto - Google Patents

processos de fabricação de um composto

Info

Publication number
BRPI0613307B8
BRPI0613307B8 BRPI0613307A BRPI0613307A BRPI0613307B8 BR PI0613307 B8 BRPI0613307 B8 BR PI0613307B8 BR PI0613307 A BRPI0613307 A BR PI0613307A BR PI0613307 A BRPI0613307 A BR PI0613307A BR PI0613307 B8 BRPI0613307 B8 BR PI0613307B8
Authority
BR
Brazil
Prior art keywords
compound
formula
manufacturing processes
manufacturing
hydrogen gas
Prior art date
Application number
BRPI0613307A
Other languages
English (en)
Inventor
Weber Beat
Rosenberger Stefan
Original Assignee
Galderma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Sa filed Critical Galderma Sa
Publication of BRPI0613307A2 publication Critical patent/BRPI0613307A2/pt
Publication of BRPI0613307B1 publication Critical patent/BRPI0613307B1/pt
Publication of BRPI0613307B8 publication Critical patent/BRPI0613307B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/023—Preparation; Separation; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms

Abstract

processos de fabricação de um composto a presente invenção trata de um processo de fabricação de um composto de fórmula (la), processo esse que compreende: (i) colocar um composto de fórmula (iii) em contato com um composto de fórmula (iv) na presença de um catalisador de paládio, metanol e gás de hidrogênio, e a referida etapa (i) é realizada de preferência sob condições básicas com adição de ácido acético após a cessação do consumo de gás de hidrogênio.
BRPI0613307A 2005-07-28 2006-07-27 processos de fabricação de um composto BRPI0613307B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05291611.1 2005-07-28
EP05291611A EP1749826A1 (en) 2005-07-28 2005-07-28 Process of producing bepromoline
PCT/IB2006/003362 WO2007012984A2 (en) 2005-07-28 2006-07-27 Process of producing bepromoline

Publications (3)

Publication Number Publication Date
BRPI0613307A2 BRPI0613307A2 (pt) 2010-12-28
BRPI0613307B1 BRPI0613307B1 (pt) 2021-04-06
BRPI0613307B8 true BRPI0613307B8 (pt) 2021-05-25

Family

ID=35064906

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0613307A BRPI0613307B8 (pt) 2005-07-28 2006-07-27 processos de fabricação de um composto

Country Status (12)

Country Link
US (2) US7795425B2 (pt)
EP (2) EP1749826A1 (pt)
AR (1) AR054873A1 (pt)
BR (1) BRPI0613307B8 (pt)
CA (1) CA2616160C (pt)
CY (1) CY1113779T1 (pt)
DK (1) DK1912961T3 (pt)
ES (1) ES2399245T3 (pt)
PL (1) PL1912961T3 (pt)
PT (1) PT1912961E (pt)
SI (1) SI1912961T1 (pt)
WO (1) WO2007012984A2 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1749826A1 (en) * 2005-07-28 2007-02-07 Galderma S.A. Process of producing bepromoline
EP1935889A1 (en) * 2006-12-21 2008-06-25 Galderma S.A. Process of producing amorolfine
ITFI20090032A1 (it) * 2009-02-20 2010-08-21 Synteco S P A Prodotti Di Sintesi Per L Ind Processo di produzione industriale dell'amorolfina cloridrato
WO2011066735A1 (en) * 2009-12-01 2011-06-09 Zhejiang Hisoar Pharmaceutical Co., Ltd An Amorolfine HCl Crystal and the Preparation thereof
CN102887872B (zh) * 2011-12-30 2015-06-24 浙江海翔药业股份有限公司 一种盐酸阿莫罗芬的制备方法
CN109232458A (zh) * 2018-06-15 2019-01-18 南通常佑药业科技有限公司 一种手性吗啉化合物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046280A (en) * 1955-11-24 1962-07-24 Philips Corp Primary, secondary and tertiary amines having a spasmolytic effect and method of producing these compounds
AT354187B (de) * 1976-11-22 1979-12-27 Hoffmann La Roche Fungizides mittel
DE2656747C2 (de) * 1976-12-15 1984-07-05 Basf Ag, 6700 Ludwigshafen Morpholinderivate
US4283534A (en) * 1979-04-11 1981-08-11 Basf Aktiengesellschaft Reductive alkylation of nitrogen heterocycles
ZW15780A1 (en) 1979-08-17 1981-03-18 Hoffmann La Roche Heterocyclic compounds
EP1749826A1 (en) * 2005-07-28 2007-02-07 Galderma S.A. Process of producing bepromoline
EP1935889A1 (en) * 2006-12-21 2008-06-25 Galderma S.A. Process of producing amorolfine

Also Published As

Publication number Publication date
EP1749826A1 (en) 2007-02-07
PL1912961T3 (pl) 2013-04-30
SI1912961T1 (sl) 2013-04-30
US8242268B2 (en) 2012-08-14
BRPI0613307A2 (pt) 2010-12-28
US20080269483A1 (en) 2008-10-30
US7795425B2 (en) 2010-09-14
WO2007012984A2 (en) 2007-02-01
US20100311967A1 (en) 2010-12-09
CA2616160A1 (en) 2007-02-01
ES2399245T3 (es) 2013-03-26
CA2616160C (en) 2014-02-11
BRPI0613307B1 (pt) 2021-04-06
AR054873A1 (es) 2007-07-25
CY1113779T1 (el) 2016-07-27
EP1912961A2 (en) 2008-04-23
EP1912961B1 (en) 2012-12-05
PT1912961E (pt) 2013-02-04
DK1912961T3 (da) 2013-02-11
WO2007012984A3 (en) 2007-06-14

Similar Documents

Publication Publication Date Title
BRPI0613307B8 (pt) processos de fabricação de um composto
BRPI0702604A (pt) método de conversão de etanol em estoque de base para combustìvel diesel
BRPI0506420A (pt) processo para preparar um material de estrutura organometálica, material de estrutura organometálica, corpo moldado e, métodos para usar um material de estrutura organometálica, e para catalisar uma reação de um composto orgánico
TW200602355A (en) Chemically modified polyaminosaccharide by a hydrocarbyl sultone compound
BRPI0712272A2 (pt) Processos para a fabricação de pelo menos um isoocteno, de produtos de reação, de pelo menos um isooctano e de pelos menos um isooctanol
MY144768A (en) Process for the conversion of hydrocarbons to c2-oxygenates
BRPI0507540A (pt) processo para a produção de conjugados de polissacarìdeos e polinucleotìdeos
BRPI0816911A8 (pt) Processo para preparação de 4-aminobut-2-enolidas
BRPI0516595A (pt) processo para fabricar um composto, e, composto
WO2010032259A3 (en) Process for the preparation of efavirenz
BRPI0512310A (pt) compostos quìmicos
BRPI0607647A2 (pt) processo para transalquilar aromáticos usando um catalisador de alta atividade
AR061016A1 (es) Proceso para la purificacion de anastrozol
CL2012000114A1 (es) Proceso para la preparacion de compuestos derivados de 5-amino-benzonorbornadieno donde se hacer reaccionar un compuesto de 5-halo-benzonorbornadieno con una bencilamina en prensecia de un catalizador de paladio.
ATE458133T1 (de) Abgassystem
BR112012013909A2 (pt) processo para reagir dióxido de carbono com hidrogênio
DOP2009000088A (es) Pirazoles sustituidos que presentan actividad anticancerígena
ES2364081T5 (es) Procedimiento para preparar diaminodifenilmetanos
WO2009135598A8 (en) Process for preparing substituted biphenylanilides
AR051341A1 (es) Proceso para la preparacion de derivados de [1,4,5]-oxadiazepina
DK1708809T3 (da) Syntese af ædelmetalsulfidkatalysatorer i et sulfidion-frit vandigt miljø
ES2422161T3 (es) Procedimiento para producir 1-(3,4-diclorobencil)-5-octilbiguanida o una sal de la misma
BRPI0818853A2 (pt) Processos para a redução na quantidade de compostos de enxofre, cianeto de hidrogênio, ácido fórmico e derivados de ácido fórmico em gás de síntese, para a preparação de metanol, éter dimetílico e/ou hidrocarbonetos em forma gasosa ou líquida a partir de gás de síntese, e, para apreparação de hidrocarbonetos em forma líquida a partir de gás de síntese
ATE497942T1 (de) Integriertes verfahren zur herstellung von benzol und ammoniak ausgehend von aliphatischen kohlenwasserstoffen und stickstoff
BRPI0519246A2 (pt) processo para decompor ciclohexilhidroperàxido

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 06/04/2021, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/07/2006 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF