BRPI0611326A2 - receptores de células t melano-a de alta afinidade - Google Patents

receptores de células t melano-a de alta afinidade Download PDF

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Publication number
BRPI0611326A2
BRPI0611326A2 BRPI0611326-5A BRPI0611326A BRPI0611326A2 BR PI0611326 A2 BRPI0611326 A2 BR PI0611326A2 BR PI0611326 A BRPI0611326 A BR PI0611326A BR PI0611326 A2 BRPI0611326 A2 BR PI0611326A2
Authority
BR
Brazil
Prior art keywords
tcr
seq
gly
gln
val
Prior art date
Application number
BRPI0611326-5A
Other languages
English (en)
Portuguese (pt)
Inventor
Bent Karsten Jakobsen
Nathaniel Ross Liddy
Original Assignee
Medigene Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medigene Ltd filed Critical Medigene Ltd
Publication of BRPI0611326A2 publication Critical patent/BRPI0611326A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BRPI0611326-5A 2005-06-01 2006-05-31 receptores de células t melano-a de alta afinidade BRPI0611326A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0511124.0 2005-06-01
GBGB0511124.0A GB0511124D0 (en) 2005-06-01 2005-06-01 High affinity melan-a t cell receptors
PCT/GB2006/001980 WO2006129085A2 (en) 2005-06-01 2006-05-31 High affinity melan-a t cell receptors

Publications (1)

Publication Number Publication Date
BRPI0611326A2 true BRPI0611326A2 (pt) 2010-08-31

Family

ID=34834931

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0611326-5A BRPI0611326A2 (pt) 2005-06-01 2006-05-31 receptores de células t melano-a de alta afinidade

Country Status (12)

Country Link
US (1) US8217144B2 (ja)
EP (1) EP1893642A2 (ja)
JP (1) JP2008545426A (ja)
CN (1) CN101189261B (ja)
AU (1) AU2006253941B2 (ja)
BR (1) BRPI0611326A2 (ja)
CA (1) CA2610786A1 (ja)
EA (1) EA012507B1 (ja)
GB (1) GB0511124D0 (ja)
MX (1) MX2007014919A (ja)
WO (1) WO2006129085A2 (ja)
ZA (1) ZA200710009B (ja)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7994298B2 (en) 2004-09-24 2011-08-09 Trustees Of Dartmouth College Chimeric NK receptor and methods for treating cancer
US8088379B2 (en) * 2006-09-26 2012-01-03 The United States Of America As Represented By The Department Of Health And Human Services Modified T cell receptors and related materials and methods
WO2008042814A2 (en) 2006-09-29 2008-04-10 California Institute Of Technology Mart-1 t cell receptors
EP2087000A2 (en) * 2006-09-29 2009-08-12 Immunocore Ltd. T cell therapies
GB0816096D0 (en) * 2008-09-04 2008-10-15 Medigene Ltd Diabetes t cell receptors
GB0911566D0 (en) 2009-07-03 2009-08-12 Immunocore Ltd T cell receptors
US9181527B2 (en) 2009-10-29 2015-11-10 The Trustees Of Dartmouth College T cell receptor-deficient T cell compositions
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
WO2012122042A2 (en) * 2011-03-04 2012-09-13 Shire Human Genetic Therapies, Inc. Peptide linkers for polypeptide compositions and methods for using same
WO2013033626A2 (en) 2011-08-31 2013-03-07 Trustees Of Dartmouth College Nkp30 receptor targeted therapeutics
US9751928B2 (en) 2012-05-03 2017-09-05 Fred Hutchinson Cancer Research Center Enhanced affinity T cell receptors and methods for making the same
US9790278B2 (en) 2012-05-07 2017-10-17 The Trustees Of Dartmouth College Anti-B7-H6 antibody, fusion proteins, and methods of using the same
EP3718556A3 (en) 2012-08-31 2020-12-30 University Of Virginia Patent Foundation Target peptides for immunotherapy and diagnostics
CA2883673A1 (en) 2012-09-05 2014-03-13 University Of Virginia Patent Foundation Target peptides for colorectal cancer therapy and diagnostics
PL3071593T3 (pl) * 2013-11-22 2019-11-29 Univ Illinois Konstruowane ludzkie receptory komórek T o wysokim powinowactwie
WO2015160928A2 (en) 2014-04-15 2015-10-22 University Of Virginia Patent Foundation Isolated t cell receptors and methods of use therefor
EP2944652A1 (en) * 2014-05-13 2015-11-18 Technische Universität München Glypican-3-specific T-cell receptors and their uses for immunotherapy of hepatocellular carcinoma
CA2955984A1 (en) 2014-07-22 2016-01-28 The University Of Notre Dame Du Lac Molecular constructs and uses thereof
GB201417803D0 (en) * 2014-10-08 2014-11-19 Adaptimmune Ltd T cell receptors
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
GB201516277D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR libraries
GB201516272D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
MX2018014863A (es) 2016-06-02 2019-09-11 Immunocore Ltd Régimen de dosificación para proteína de fusión de tcr especifico de gp100 - scfv anti - cd3.
GB201617714D0 (en) 2016-10-19 2016-11-30 Ucl Business Plc T Cell receptor
SG11201908527SA (en) * 2017-03-15 2019-10-30 Hutchinson Fred Cancer Res High affinity mage-a1-specific tcrs and uses thereof
JP2020530274A (ja) * 2017-06-30 2020-10-22 アカデミス・ジーケンハイス・ライデン・ハー・オー・デー・エヌ・エルユーエムセーＡｃａｄｅｍｉｓｃｈ Ｚｉｅｋｅｎｈｕｉｓ Ｌｅｉｄｅｎ Ｈ．Ｏ．Ｄ．Ｎ． Ｌｕｍｃ 造血器腫瘍の処置
CA3078472A1 (en) 2017-10-06 2019-04-11 Oslo Universitetssykehus Hf Chimeric antigen receptors
CN112646024B (zh) * 2019-10-10 2023-03-24 香雪生命科学技术（广东）有限公司 一种识别kras突变的t细胞受体及其编码序列

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2457652C (en) 2001-08-31 2012-08-07 Avidex Limited Soluble t cell receptor
US7751825B2 (en) 2002-06-27 2010-07-06 Qualcomm Incorporated Controlling geographic location information of devices operating in wireless communication systems
JP4436319B2 (ja) 2002-10-09 2010-03-24 メディジーン リミテッド 単鎖組換えｔ細胞レセプター
EP2048159B1 (en) * 2002-11-09 2014-01-01 Immunocore Ltd. T cell receptor display
JP2006523437A (ja) * 2002-12-03 2006-10-19 アヴィデックス リミテッド レセプター複合体
AU2005246073B2 (en) * 2004-05-19 2010-10-28 Adaptimmune Limited Method of improving T cell receptors
NZ550810A (en) 2004-05-19 2009-05-31 Immunocore Ltd High affinity NY-ESO T cell receptor

Also Published As

Publication number Publication date
EA012507B1 (ru) 2009-10-30
EA200702677A1 (ru) 2008-06-30
AU2006253941B2 (en) 2012-04-12
CN101189261B (zh) 2012-12-05
ZA200710009B (en) 2008-09-25
AU2006253941A2 (en) 2008-03-06
WO2006129085A3 (en) 2007-02-01
WO2006129085A2 (en) 2006-12-07
US20080292549A1 (en) 2008-11-27
MX2007014919A (es) 2009-02-16
EP1893642A2 (en) 2008-03-05
JP2008545426A (ja) 2008-12-18
CA2610786A1 (en) 2006-12-07
US8217144B2 (en) 2012-07-10
AU2006253941A1 (en) 2006-12-07
CN101189261A (zh) 2008-05-28
GB0511124D0 (en) 2005-07-06

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2161 DE 05/06/2012.