BRPI0608103A2 - dispositivo para detecção e identificação rápida de microorganismos isolados sem cultura preliminar - Google Patents
dispositivo para detecção e identificação rápida de microorganismos isolados sem cultura preliminarInfo
- Publication number
- BRPI0608103A2 BRPI0608103A2 BRPI0608103-7A BRPI0608103A BRPI0608103A2 BR PI0608103 A2 BRPI0608103 A2 BR PI0608103A2 BR PI0608103 A BRPI0608103 A BR PI0608103A BR PI0608103 A2 BRPI0608103 A2 BR PI0608103A2
- Authority
- BR
- Brazil
- Prior art keywords
- microchannels
- microchannel
- microorganisms
- filter
- identification
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
Abstract
DISPOSITIVO PARA DETECçãO E IDENTIFICAçãO RáPIDA DE MICROORGANISMOS ISOLADOS SEM CULTURA PRELIMINAR. Esta invenção descreve um dispositivo que compreende uma placa de microcanais, filtro e suporte poroso para o filtro, que durante o desempenho do método é substituído por um bloco de ágar puro, e elementos estruturais de apoio. O dispositivo destina-se à detecção e/ou identificação rápida de microorganismos. Os microorganismos são retidos pela filtração em microcanais longos (diâmetro/comprimento= 1/10 - 1/100), cilíndricos, paralelos, abertos em ambos os lados e com uma das extremidades presa a um filtro. Uma placa de microcanais abriga diversos microcanais (canal com 1 - 3Opm de diâmetro possível, 100 - 1000<109>m de comprimento e um número de microcanais por cm^ 2^ = 100.000 - 1.000.000). A placa de microcanais com as células retidas na superfície do filtro é fixada a um bloco de ágar impregnado por substrato(s) artificial(is), de forma que as moléculas dos substratos artificiais encherão todos os microcanais. As células retidas produzirão moléculas coloridas ou fluorescentes dos substratos artificiais. Estas moléculas são recolhidas no volume muito pequeno de um microcanal. O volume extremamente reduzido de um microcanal (1/25 milionésima parte de um mililitro) permite recolher uma concentração detectável de substâncias coloridas ou fluorescentes em um período de tempo bastante curto (vários minutos), O método da enzima-substrato artificial é capaz de detectar até mesmo uma única célula de uma amostra filtrada e/ou identificá-la pelo imunoensaio de enzima.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/109,857 US8663909B2 (en) | 2002-05-09 | 2005-04-20 | Device for rapid detection and identification of single microorganisms without preliminary growth |
PCT/US2006/015321 WO2006113930A2 (en) | 2005-04-20 | 2006-04-20 | Device for rapid detection and identification of single microoganisms without preliminary growth |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0608103A2 true BRPI0608103A2 (pt) | 2009-11-03 |
Family
ID=37115982
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0608103-7A BRPI0608103A2 (pt) | 2005-04-20 | 2006-04-20 | dispositivo para detecção e identificação rápida de microorganismos isolados sem cultura preliminar |
Country Status (5)
Country | Link |
---|---|
US (1) | US8663909B2 (pt) |
EP (1) | EP1871892A4 (pt) |
CN (1) | CN101203617B (pt) |
BR (1) | BRPI0608103A2 (pt) |
WO (1) | WO2006113930A2 (pt) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1432786B1 (en) | 2001-09-06 | 2009-07-22 | Genomic Profiling Systems, Inc. | Rapid detection of replicating cells |
US8663909B2 (en) * | 2002-05-09 | 2014-03-04 | Nanologix, Inc. | Device for rapid detection and identification of single microorganisms without preliminary growth |
CA2956645A1 (en) | 2003-07-12 | 2005-03-31 | David A. Goldberg | Sensitive and rapid biodetection |
JP2008523820A (ja) | 2004-12-16 | 2008-07-10 | アクセラー8 テクノロジー コーポレイション | 高速の微生物検出および抗菌剤感受性試験 |
US9057046B2 (en) | 2005-09-26 | 2015-06-16 | Rapid Micro Biosystems, Inc. | Cassette containing growth medium |
JP4410747B2 (ja) * | 2005-09-30 | 2010-02-03 | Hoya株式会社 | 磁気記録ディスク用潤滑剤の成分比測定方法および磁気記録ディスクの製造方法 |
WO2007044047A1 (en) * | 2005-10-13 | 2007-04-19 | Alamo Scientific, Inc. | Apparatus and method for microbial and forensic sampling and manipulation |
FR2897783B1 (fr) * | 2006-02-24 | 2008-05-30 | Millipore Corp | Dispositif pour le controle microbiologique, ensembles de controle et d'incubation le comportant et procede le mettant en oeuvre |
CA2704309C (en) | 2006-11-03 | 2017-02-28 | Trustees Of Tufts College | Electroactive biopolymer optical and electro-optical devices and method of manufacturing the same |
US8529835B2 (en) | 2006-11-03 | 2013-09-10 | Tufts University | Biopolymer sensor and method of manufacturing the same |
US20080153125A1 (en) * | 2006-11-10 | 2008-06-26 | Advanced Analytical Technologies, Inc. | Rapid detection of microorganisms in fluids |
US20100190204A1 (en) * | 2007-03-22 | 2010-07-29 | Nanologix, Inc. | Detection and Identification of Microorganisms on Transparent Permeable Membranes |
US7853969B2 (en) | 2007-04-03 | 2010-12-14 | Google Inc. | Log processing to determine impression values using reliable durations |
US7802280B2 (en) * | 2007-04-03 | 2010-09-21 | Google Inc. | Approving transcoded advertisements in advertisement front end |
FR2915487B1 (fr) * | 2007-04-26 | 2009-06-05 | Millipore Corp | Ensemble et procede pour analyse microbiologique |
EP3087858B1 (en) | 2008-06-13 | 2021-04-28 | NIKE Innovate C.V. | Footwear having sensor system |
US9002680B2 (en) * | 2008-06-13 | 2015-04-07 | Nike, Inc. | Foot gestures for computer input and interface control |
US10070680B2 (en) | 2008-06-13 | 2018-09-11 | Nike, Inc. | Footwear having sensor system |
US9549585B2 (en) | 2008-06-13 | 2017-01-24 | Nike, Inc. | Footwear having sensor system |
US9834806B2 (en) * | 2008-06-27 | 2017-12-05 | Hitachi Plant Services Co., Ltd. | Microbe-collecting carrier cartridge, carrier treating apparatus, and method of measuring microbes |
CA2738317C (en) | 2008-09-24 | 2020-01-14 | Straus Holdings Inc. | Imaging analyzer for testing analytes |
EP2368103B1 (en) * | 2008-11-24 | 2017-08-02 | Koninklijke Philips N.V. | Method for rapid filter analysis of fluid samples |
US8255949B1 (en) | 2009-01-07 | 2012-08-28 | Google Inc. | Television program targeting for advertising |
US20120107925A1 (en) * | 2009-03-20 | 2012-05-03 | Mo Huang Li | Devices for separating cells and methods of using them |
EP2241875A1 (en) | 2009-04-14 | 2010-10-20 | Koninklijke Philips Electronics N.V. | Up-concentration of organic microobjects for microscopic imaging. |
JP5747043B2 (ja) * | 2009-12-22 | 2015-07-08 | スリーエム イノベイティブ プロパティズ カンパニー | 微生物を検出する方法及びそのためのキット |
JP5881694B2 (ja) * | 2010-06-30 | 2016-03-09 | スリーエム イノベイティブ プロパティズ カンパニー | 吸水性フィルターアセンブリを有するフィルタープレート物品 |
EP2638491B1 (en) | 2010-11-10 | 2022-10-05 | NIKE Innovate C.V. | Systems and methods for time-based athletic activity measurement and display |
CA2827687C (en) | 2011-02-17 | 2016-12-20 | Nike International Ltd. | Footwear having sensor system |
KR101853239B1 (ko) | 2011-02-17 | 2018-04-27 | 나이키 이노베이트 씨.브이. | 위치 맵핑 |
US9381420B2 (en) | 2011-02-17 | 2016-07-05 | Nike, Inc. | Workout user experience |
KR101896204B1 (ko) | 2011-02-17 | 2018-09-07 | 나이키 이노베이트 씨.브이. | 센서 시스템을 가지는 신발류 |
US10254204B2 (en) | 2011-03-07 | 2019-04-09 | Accelerate Diagnostics, Inc. | Membrane-assisted purification |
WO2012122314A2 (en) | 2011-03-07 | 2012-09-13 | Accelr8 Technology Corporation | Rapid cell purification systems |
CN102367469B (zh) * | 2011-10-24 | 2013-07-31 | 宁波大学 | 一种夜光藻活细胞的定量浓缩方法 |
PL3327110T3 (pl) | 2011-11-07 | 2020-07-27 | Rapid Micro Biosystems, Inc. | Kaseta do badania sterylności |
CN102517198B (zh) * | 2012-01-10 | 2014-07-30 | 济南市疾病预防控制中心 | 一种用于毛细管培养法检测或筛选微生物的装置 |
CN102517375B (zh) * | 2012-01-10 | 2013-08-21 | 济南市疾病预防控制中心 | 一种利用毛细管培养法检测微生物的方法 |
US11684111B2 (en) | 2012-02-22 | 2023-06-27 | Nike, Inc. | Motorized shoe with gesture control |
US20130213146A1 (en) | 2012-02-22 | 2013-08-22 | Nike, Inc. | Footwear Having Sensor System |
US11071344B2 (en) | 2012-02-22 | 2021-07-27 | Nike, Inc. | Motorized shoe with gesture control |
US20130213147A1 (en) | 2012-02-22 | 2013-08-22 | Nike, Inc. | Footwear Having Sensor System |
CN107841461A (zh) | 2012-04-16 | 2018-03-27 | 快速微型生物系统公司 | 细胞培养装置 |
WO2014047770A1 (en) * | 2012-09-25 | 2014-04-03 | General Electric Company | Disposable container for bioburden sample collection and detection |
US9043004B2 (en) | 2012-12-13 | 2015-05-26 | Nike, Inc. | Apparel having sensor system |
US10926133B2 (en) | 2013-02-01 | 2021-02-23 | Nike, Inc. | System and method for analyzing athletic activity |
US9743861B2 (en) | 2013-02-01 | 2017-08-29 | Nike, Inc. | System and method for analyzing athletic activity |
US11006690B2 (en) | 2013-02-01 | 2021-05-18 | Nike, Inc. | System and method for analyzing athletic activity |
US9279734B2 (en) | 2013-03-15 | 2016-03-08 | Nike, Inc. | System and method for analyzing athletic activity |
US9677109B2 (en) | 2013-03-15 | 2017-06-13 | Accelerate Diagnostics, Inc. | Rapid determination of microbial growth and antimicrobial susceptibility |
US9568404B2 (en) | 2014-05-16 | 2017-02-14 | Junyu Mai | Method and apparatus for biomolecule analysis |
DE102014116050B3 (de) * | 2014-11-04 | 2016-02-25 | Universität Potsdam | Vorrichtung und Verfahren zur Identifizierung von Mikroorganismen |
US10023895B2 (en) | 2015-03-30 | 2018-07-17 | Accelerate Diagnostics, Inc. | Instrument and system for rapid microogranism identification and antimicrobial agent susceptibility testing |
US10253355B2 (en) | 2015-03-30 | 2019-04-09 | Accelerate Diagnostics, Inc. | Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing |
CN109370904A (zh) * | 2018-12-22 | 2019-02-22 | 精迅分子检测(深圳)有限公司 | 一种带有指示装置的培养瓶 |
US11618032B2 (en) | 2020-08-31 | 2023-04-04 | International Business Machines Corporation | Multiplexed testing strip device |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5650323A (en) * | 1991-06-26 | 1997-07-22 | Costar Corporation | System for growing and manipulating tissue cultures using 96-well format equipment |
US5670113A (en) * | 1991-12-20 | 1997-09-23 | Sibia Neurosciences, Inc. | Automated analysis equipment and assay method for detecting cell surface protein and/or cytoplasmic receptor function using same |
WO1993019199A1 (en) * | 1992-03-20 | 1993-09-30 | Celsis Limited | Method and apparatus for the analysis of biological material |
US5716798A (en) * | 1992-09-22 | 1998-02-10 | Becton Dickinson And Company | Enhanced detection of microorganisms in samples |
US6893816B1 (en) * | 1993-10-28 | 2005-05-17 | Houston Advanced Research Center | Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions |
CA2179364C (en) | 1995-06-27 | 1999-09-28 | Klaus W. Berndt | Method and apparatus for detecting microorganisms |
US5660990A (en) * | 1995-08-18 | 1997-08-26 | Immunivest Corporation | Surface immobilization of magnetically collected materials |
US6696286B1 (en) * | 1997-04-09 | 2004-02-24 | 3M Innovative Properties Company | Method and devices for detecting and enumerating microorganisms |
US5962250A (en) * | 1997-10-28 | 1999-10-05 | Glaxo Group Limited | Split multi-well plate and methods |
US6210910B1 (en) * | 1998-03-02 | 2001-04-03 | Trustees Of Tufts College | Optical fiber biosensor array comprising cell populations confined to microcavities |
EP1151139A2 (en) | 1999-01-25 | 2001-11-07 | UT-Battelle, LLC | Multifunctional and multispectral biosensor devices and methods of use |
US7338773B2 (en) * | 2000-04-14 | 2008-03-04 | Millipore Corporation | Multiplexed assays of cell migration |
EP1284818B1 (en) | 2000-05-15 | 2006-11-22 | Tecan Trading AG | Bidirectional flow centrifugal microfluidic devices |
ES2331108T3 (es) * | 2000-05-18 | 2009-12-22 | Millipore Corporation | Placa de pocillos multiples con filtro adherido por adhesivo. |
US7351376B1 (en) | 2000-06-05 | 2008-04-01 | California Institute Of Technology | Integrated active flux microfluidic devices and methods |
EP1330306A2 (en) * | 2000-10-10 | 2003-07-30 | BioTrove, Inc. | Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof |
US6418968B1 (en) * | 2001-04-20 | 2002-07-16 | Nanostream, Inc. | Porous microfluidic valves |
US6811752B2 (en) * | 2001-05-15 | 2004-11-02 | Biocrystal, Ltd. | Device having microchambers and microfluidics |
US6729352B2 (en) | 2001-06-07 | 2004-05-04 | Nanostream, Inc. | Microfluidic synthesis devices and methods |
JP3809165B2 (ja) * | 2001-06-14 | 2006-08-16 | ミリポア・コーポレイション | マルチウェル試験装置 |
US20030096268A1 (en) * | 2001-07-06 | 2003-05-22 | Michael Weiner | Method for isolation of independent, parallel chemical micro-reactions using a porous filter |
US8361783B2 (en) * | 2002-05-09 | 2013-01-29 | Nanologix, Inc. | Micromethod and device for the rapid detection, enumeration and identification of microorganisms |
US7781159B2 (en) * | 2002-05-09 | 2010-08-24 | Nanologix, Inc. | Micromethod and device for rapid detection, enumeration and identification of entities |
US8663909B2 (en) * | 2002-05-09 | 2014-03-04 | Nanologix, Inc. | Device for rapid detection and identification of single microorganisms without preliminary growth |
US7524623B2 (en) * | 2003-07-28 | 2009-04-28 | Nanologix, Inc. | Method and device for rapid detection of microorganisms by changing the shape of micro-colonies |
US20060088895A1 (en) | 2004-01-30 | 2006-04-27 | Wanders Bart J | Systems, methods and reagents for the detection of biological and chemical agents using dynamic surface generation and imaging |
-
2005
- 2005-04-20 US US11/109,857 patent/US8663909B2/en not_active Expired - Fee Related
-
2006
- 2006-04-20 WO PCT/US2006/015321 patent/WO2006113930A2/en active Application Filing
- 2006-04-20 BR BRPI0608103-7A patent/BRPI0608103A2/pt not_active Application Discontinuation
- 2006-04-20 EP EP06758523A patent/EP1871892A4/en not_active Ceased
- 2006-04-20 CN CN2006800221629A patent/CN101203617B/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN101203617A (zh) | 2008-06-18 |
US8663909B2 (en) | 2014-03-04 |
US20050221403A1 (en) | 2005-10-06 |
EP1871892A4 (en) | 2009-08-12 |
WO2006113930A2 (en) | 2006-10-26 |
CN101203617B (zh) | 2012-03-14 |
EP1871892A2 (en) | 2008-01-02 |
WO2006113930A3 (en) | 2007-08-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0608103A2 (pt) | dispositivo para detecção e identificação rápida de microorganismos isolados sem cultura preliminar | |
BRPI0511977A (pt) | dispositivos e métodos para remover agentes alvo de uma amostra | |
DE60014676D1 (de) | Vorrichtung und verfahren zur analyse flüssiger proben | |
WO2009049171A3 (en) | System for conducting the identification of bacteria in urine | |
WO2007072472A3 (en) | Systems and methods for analyzing and manipulating biological samples | |
AR053251A1 (es) | Estrategias nuevas de etiquetado para la deteccion sensible de analitos | |
DE602005013957D1 (de) | Verfahren zur durchführung von vollbluttests | |
CA2354379A1 (en) | Method for isolating dna from biological materials | |
EP2626436A3 (en) | Method for detecting a target using chemically modified aptamers enriched for slow off-rates | |
MX338460B (es) | Aparatos, metodos y reactivos de ensayo. | |
WO2003066906A3 (en) | Diagnostic microarray and method of use thereof | |
EP2402463A3 (en) | Nucleic acid molecules and collections thereof, their application and identification | |
ATE265040T1 (de) | Biochemische reinigungsgeräte mit immobilisierten fangsonden und ihre anwendungen | |
AU2003243558A1 (en) | Test strip for detection of analyte and methods of use | |
WO2003106623A3 (en) | NON-EFFECTIVE PRENATAL EARLY TESTING FOR DETECTION OF EARTHPLUSTS AND HEREDITARY CONDITIONS | |
WO2007041692A3 (en) | Microfluidic detection of analytes | |
WO2006076567A3 (en) | Microfluidic rare cell detection device | |
WO2008070865A3 (en) | Materials and methods for efficient and accurate detection of analytes | |
BRPI0518405A2 (pt) | detecÇço de vÍrus papiloma humano (hpv) utilizando sondas de Ácido nuclÉico, microcontas e separador de cÉlulas ativado fluorescente (facs) | |
HK1082296A1 (en) | Adhered membranes retaining porosity and biological activity in assay device for measuring serum cholesterol associated with high-density lipoproteins | |
PT1329724E (pt) | Dispositivo e metodo de doeseamento de lipoproteina de alta densidade | |
MX2009006902A (es) | Metodo y dispositivo para determinar poblaciones celulares menores en poblaciones celulares heterogeneas. | |
WO2006110537A3 (en) | Particulate separation filters and methods | |
WO2002012892A3 (en) | Rapid multiple panel of biomarkers in laboratory blood tests for tia/stroke | |
WO2004106535A3 (en) | Enhanced cellular assay method for use in flow cytometry or similar instruments using optically resonant particles |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07A | Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O C/C 11, 8O C/C 13 E 25 DA LPI. |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |
|
B15K | Others concerning applications: alteration of classification |
Free format text: PROCEDIMENTO AUTOMATICO DE RECLASSIFICACAO. AS CLASSIFICACOES IPC ANTERIORES ERAM: C12Q 1/00; C12Q 1/68; G01N 1/00; G01N 1/18; G01N 15/06; G01N 21/00; G01N 21/75; G01N 33/53; G01N 33/566; C12M 1/34; C12M 1/36; C12M 1/38; C12M 3/00; B01L 11/00; B32B 5/02. Ipc: C12Q 1/04 (2006.01) Ipc: C12Q 1/04 (2006.01) |