BRPI0517682A - composição contendo vlp e peptìdeo amilóide-beta - Google Patents
composição contendo vlp e peptìdeo amilóide-betaInfo
- Publication number
- BRPI0517682A BRPI0517682A BRPI0517682-4A BRPI0517682A BRPI0517682A BR PI0517682 A BRPI0517682 A BR PI0517682A BR PI0517682 A BRPI0517682 A BR PI0517682A BR PI0517682 A BRPI0517682 A BR PI0517682A
- Authority
- BR
- Brazil
- Prior art keywords
- composition containing
- beta peptide
- vlp
- construct
- amyloid beta
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6075—Viral proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Psychology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0424563A GB0424563D0 (en) | 2004-11-05 | 2004-11-05 | Organic compounds |
| PCT/EP2005/011788 WO2006048295A1 (en) | 2004-11-05 | 2005-11-03 | Composition compri sing vlp and amyloid - beta peptide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0517682A true BRPI0517682A (pt) | 2008-10-14 |
Family
ID=33523293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0517682-4A BRPI0517682A (pt) | 2004-11-05 | 2005-11-03 | composição contendo vlp e peptìdeo amilóide-beta |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US7867499B2 (https=) |
| EP (2) | EP2286830A3 (https=) |
| JP (2) | JP2008515954A (https=) |
| KR (1) | KR20070073882A (https=) |
| CN (1) | CN101048174A (https=) |
| AR (1) | AR054092A1 (https=) |
| AU (2) | AU2005300692A1 (https=) |
| BR (1) | BRPI0517682A (https=) |
| CA (1) | CA2581300A1 (https=) |
| EC (1) | ECSP077415A (https=) |
| GB (1) | GB0424563D0 (https=) |
| GT (1) | GT200500313A (https=) |
| IL (1) | IL182692A (https=) |
| MA (1) | MA29020B1 (https=) |
| MX (1) | MX2007005430A (https=) |
| MY (1) | MY148584A (https=) |
| NO (1) | NO20072743L (https=) |
| NZ (1) | NZ583688A (https=) |
| PE (1) | PE20061047A1 (https=) |
| RU (1) | RU2415677C2 (https=) |
| SG (1) | SG170646A1 (https=) |
| TN (1) | TNSN07166A1 (https=) |
| TW (1) | TWI380825B (https=) |
| WO (1) | WO2006048295A1 (https=) |
| ZA (1) | ZA200702369B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0424563D0 (en) * | 2004-11-05 | 2004-12-08 | Novartis Ag | Organic compounds |
| BR112012024708A2 (pt) * | 2010-03-29 | 2016-06-07 | Novartis Ag | composição de compostos orgânicos |
| US12233177B2 (en) | 2019-09-16 | 2025-02-25 | Amgen Inc. | Method for external sterilization of drug delivery device |
| WO2022152939A1 (en) | 2021-01-18 | 2022-07-21 | Conserv Bioscience Limited | Coronavirus immunogenic compositions, methods and uses thereof |
Family Cites Families (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0038154B1 (en) | 1980-04-15 | 1983-09-21 | Beecham Group Plc | Allergens modified with polysarcosines |
| US5204096A (en) | 1984-03-07 | 1993-04-20 | New York Blood Center, Inc. | Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers |
| US4722840A (en) | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
| US4959314A (en) | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
| JPH01501064A (ja) | 1986-09-22 | 1989-04-13 | エモリ ユニバーシティ | ワクチンとその製法 |
| US5143726A (en) | 1986-12-09 | 1992-09-01 | The Scripps Research Institute | T cell epitopes of the hepatitis B virus nucleocapsid protein |
| GB8903313D0 (en) | 1989-02-14 | 1989-04-05 | Wellcome Found | Conjugates |
| GB8913737D0 (en) | 1989-06-15 | 1989-08-02 | Univ Birmingham | A novel anti-allergy treatment |
| US5178882A (en) | 1990-06-22 | 1993-01-12 | The Regents Of The University Of California | Viral decoy vaccine |
| US5334394A (en) | 1990-06-22 | 1994-08-02 | The Regents Of The University Of California | Human immunodeficiency virus decoy |
| US5142726A (en) * | 1991-04-03 | 1992-09-01 | Mann Robert F | Adjustable bristle length toothbrush |
| GB9114003D0 (en) | 1991-06-28 | 1991-08-14 | Mastico Robert A | Chimaeric protein |
| ZA934199B (en) | 1992-06-18 | 1994-01-10 | Akzo Nv | Carrier system against gnrh |
| US6004763A (en) | 1992-09-11 | 1999-12-21 | Institut Pasteur | Antigen-carrying microparticles and their use in the induction of humoral or cellular responses |
| JP3265577B2 (ja) * | 1992-10-13 | 2002-03-11 | デューク・ユニバーシティ | アポリポ蛋白eの4型イソ型の測定法 |
| EP0678034B1 (en) | 1993-01-11 | 1999-05-26 | Dana Farber Cancer Institute | Inducing cytotoxic t lymphocyte responses |
| US6180771B1 (en) | 1993-12-08 | 2001-01-30 | Immulogic Pharmaceutical Corp. | Nucleic acids encoding a house dust mite allergen, Der p III, and uses therefor |
| US5935821A (en) | 1995-01-17 | 1999-08-10 | Board Of Trustees Of The University Of Kentucky | Polynucleotides related to monoclonal antibody 1A7 and use for the treatment of melanoma and small cell carcinoma |
| JPH09202735A (ja) | 1996-01-25 | 1997-08-05 | Nof Corp | リポソーム型アレルギー治療薬 |
| US5786161A (en) | 1996-06-06 | 1998-07-28 | Miltenyi Biotec. Gmbh | Isolation and characterization of allergen-binding cells for diagnosis of hypersensitivity |
| SE9604815D0 (sv) | 1996-12-20 | 1996-12-20 | Pharmacia & Upjohn Ab | A metod of diagnosis |
| AU753688B2 (en) | 1997-03-10 | 2002-10-24 | Ottawa Civic Loeb Research Institute | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| EP2006303A1 (en) | 1997-04-09 | 2008-12-24 | Intellect Neurosciences, Inc. | Recombinant antibodies specific for Beta-Amyloid ends, DNA encoding and methods of use thereof |
| US8173127B2 (en) | 1997-04-09 | 2012-05-08 | Intellect Neurosciences, Inc. | Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof |
| US6169175B1 (en) | 1997-08-06 | 2001-01-02 | Centers For Disease Control And Prevention | Preparation and use of recombinant influenza A virus M2 construct vaccines |
| US6054312A (en) | 1997-08-29 | 2000-04-25 | Selective Genetics, Inc. | Receptor-mediated gene delivery using bacteriophage vectors |
| US6905686B1 (en) * | 1997-12-02 | 2005-06-14 | Neuralab Limited | Active immunization for treatment of alzheimer's disease |
| TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| EP1033998B1 (en) | 1997-12-03 | 2005-10-19 | Neuralab, Ltd. | Suppressing beta-amyloid-related changes in alzheimer's disease |
| WO1999040934A1 (en) | 1998-02-12 | 1999-08-19 | Immune Complex, Corporation | Strategically modified hepatitis b core proteins and their derivatives |
| US5990085A (en) | 1998-05-04 | 1999-11-23 | Michigan State University | Inhibin-HBc fusion protein |
| ATE314095T1 (de) | 1998-10-21 | 2006-01-15 | Us Health | Virusähnliche partikel zur induktion von autoantikörpern |
| US6380364B1 (en) | 1998-11-23 | 2002-04-30 | Loyola University Of Chicago | Chimeric biotin-binding papillomavirus protein |
| NZ512456A (en) | 1998-11-30 | 2003-10-31 | Cytos Biotechnology Ag | Ordered molecular presentation of antigens |
| EA004497B1 (ru) | 1998-12-04 | 2004-04-29 | Байоджен, Инк. | Коровые антигенные частицы hbv с множественными иммуногенными компонентами, связанными посредством пептидных лигандов |
| CN1520423A (zh) | 1999-02-25 | 2004-08-11 | ʷ��˿�������ȳ�ķ����˾ | 来源于IgE的Cε3或Cε4区的抗原决定基或拟表位,其拮抗物,及其治疗用途 |
| JP2003509020A (ja) | 1999-09-03 | 2003-03-11 | ラモット・ユニバーシティ・オーソリティ・フォー・アプライド・リサーチ・アンド・インダストリアル・ディベロップメント・リミテッド | プラーク形成疾患の診断、治療、予防に有用な薬剤、組成物、その使用法 |
| US20020052311A1 (en) | 1999-09-03 | 2002-05-02 | Beka Solomon | Methods and compostions for the treatment and/or diagnosis of neurological diseases and disorders |
| WO2001053457A2 (en) | 2000-01-21 | 2001-07-26 | University Of Connecticut Health Center | Vaccines against neurodegenerative disorders |
| ES2248283T3 (es) | 2000-02-21 | 2006-03-16 | Pharmexa A/S | Nuevo procedimiento para reducir los niveles de amiloide. |
| CA2407897A1 (en) | 2000-05-05 | 2001-11-15 | Cytos Biotechnology Ag | Molecular antigen arrays and vaccines |
| US8519005B2 (en) * | 2000-07-27 | 2013-08-27 | Thomas N. Thomas | Compositions and methods to prevent toxicity of antiinflammatory agents and enhance their efficacy |
| US7128911B2 (en) | 2001-01-19 | 2006-10-31 | Cytos Biotechnology Ag | Antigen arrays for treatment of bone disease |
| US7264810B2 (en) | 2001-01-19 | 2007-09-04 | Cytos Biotechnology Ag | Molecular antigen array |
| US7094409B2 (en) | 2001-01-19 | 2006-08-22 | Cytos Biotechnology Ag | Antigen arrays for treatment of allergic eosinophilic diseases |
| MY144532A (en) * | 2001-08-20 | 2011-09-30 | Lundbeck & Co As H | Novel method for down-regulation of amyloid |
| JP4360906B2 (ja) | 2001-09-14 | 2009-11-11 | サイトス バイオテクノロジー アーゲー | ウィルス様粒子によって誘導される免疫応答を高めるための、抗原提示細胞のインビボでの活性化 |
| US7115266B2 (en) | 2001-10-05 | 2006-10-03 | Cytos Biotechnology Ag | Angiotensin peptide-carrier conjugates and uses thereof |
| US20030219459A1 (en) | 2002-01-18 | 2003-11-27 | Cytos Biotechnology Ag | Prion protein carrier-conjugates |
| EP2351770A1 (en) | 2002-07-17 | 2011-08-03 | Cytos Biotechnology AG | Molecular antigen arrays using a virus like particle derived from the ap205 coat protein |
| NZ537003A (en) | 2002-07-18 | 2008-03-28 | Cytos Biotechnology Ag | Hapten-carrier conjugates comprising virus like particles and uses thereof |
| MXPA04011247A (es) | 2002-07-19 | 2005-02-17 | Cytos Biotechnology Ag | Conjugados portadores de grelina. |
| SI1524994T1 (sl) * | 2002-07-19 | 2011-08-31 | Cytos Biotechnology Ag | Sestavki cepiv, ki vsebujejo amiloidne beta 1-6 antigenske mreĹľe |
| WO2004016262A1 (ja) | 2002-08-12 | 2004-02-26 | Kyowa Hakko Kogyo Co., Ltd. | アミノ酸含有チュアブル錠 |
| TW200509968A (en) * | 2002-11-01 | 2005-03-16 | Elan Pharm Inc | Prevention and treatment of synucleinopathic disease |
| TW200501962A (en) * | 2003-04-01 | 2005-01-16 | Novartis Ag | Use of carbamazepine derivatives for the treatment of agitation in dementia patients |
| GB0424563D0 (en) * | 2004-11-05 | 2004-12-08 | Novartis Ag | Organic compounds |
-
2004
- 2004-11-05 GB GB0424563A patent/GB0424563D0/en not_active Ceased
-
2005
- 2005-10-28 GT GT200500313A patent/GT200500313A/es unknown
- 2005-10-28 MY MYPI20055090A patent/MY148584A/en unknown
- 2005-11-03 US US11/718,665 patent/US7867499B2/en not_active Expired - Fee Related
- 2005-11-03 AR ARP050104609A patent/AR054092A1/es unknown
- 2005-11-03 MX MX2007005430A patent/MX2007005430A/es active IP Right Grant
- 2005-11-03 BR BRPI0517682-4A patent/BRPI0517682A/pt not_active IP Right Cessation
- 2005-11-03 WO PCT/EP2005/011788 patent/WO2006048295A1/en not_active Ceased
- 2005-11-03 AU AU2005300692A patent/AU2005300692A1/en not_active Abandoned
- 2005-11-03 PE PE2005001290A patent/PE20061047A1/es not_active Application Discontinuation
- 2005-11-03 KR KR1020077010214A patent/KR20070073882A/ko not_active Ceased
- 2005-11-03 JP JP2007536128A patent/JP2008515954A/ja not_active Withdrawn
- 2005-11-03 CN CNA2005800368845A patent/CN101048174A/zh active Pending
- 2005-11-03 RU RU2007120689/15A patent/RU2415677C2/ru not_active IP Right Cessation
- 2005-11-03 SG SG200907306-5A patent/SG170646A1/en unknown
- 2005-11-03 EP EP20100177232 patent/EP2286830A3/en not_active Withdrawn
- 2005-11-03 NZ NZ583688A patent/NZ583688A/en not_active IP Right Cessation
- 2005-11-03 CA CA002581300A patent/CA2581300A1/en not_active Abandoned
- 2005-11-03 EP EP05801760A patent/EP1812050A1/en not_active Withdrawn
- 2005-11-04 TW TW094138839A patent/TWI380825B/zh not_active IP Right Cessation
-
2007
- 2007-03-22 ZA ZA200702369A patent/ZA200702369B/xx unknown
- 2007-04-19 IL IL182692A patent/IL182692A/en not_active IP Right Cessation
- 2007-04-24 EC EC2007007415A patent/ECSP077415A/es unknown
- 2007-05-04 TN TNP2007000166A patent/TNSN07166A1/fr unknown
- 2007-05-14 MA MA29899A patent/MA29020B1/fr unknown
- 2007-05-30 NO NO20072743A patent/NO20072743L/no not_active Application Discontinuation
-
2010
- 2010-02-04 AU AU2010200410A patent/AU2010200410B2/en not_active Ceased
- 2010-12-17 US US12/971,534 patent/US8460676B2/en not_active Expired - Fee Related
-
2011
- 2011-05-02 JP JP2011102847A patent/JP2011157395A/ja active Pending
-
2013
- 2013-05-13 US US13/892,552 patent/US8617566B2/en not_active Expired - Fee Related
- 2013-11-20 US US14/085,048 patent/US20140079730A1/en not_active Abandoned
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