BRPI0512935A - processo para a preparação de aminoácido úteis na preparação de moduladores receptores de peptìdeo - Google Patents

processo para a preparação de aminoácido úteis na preparação de moduladores receptores de peptìdeo

Info

Publication number
BRPI0512935A
BRPI0512935A BRPI0512935-4A BRPI0512935A BRPI0512935A BR PI0512935 A BRPI0512935 A BR PI0512935A BR PI0512935 A BRPI0512935 A BR PI0512935A BR PI0512935 A BRPI0512935 A BR PI0512935A
Authority
BR
Brazil
Prior art keywords
preparation
receptor modulators
amino acids
useful
peptide receptor
Prior art date
Application number
BRPI0512935-4A
Other languages
English (en)
Inventor
Arvind Mathur
K Selva Kumar
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of BRPI0512935A publication Critical patent/BRPI0512935A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C07C227/20—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters by hydrolysis of N-acylated amino-acids or derivatives thereof, e.g. hydrolysis of carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PROCESSO PARA A PREPARAçãO DE AMINOáCIDOS úTEIS NA PREPARAçãO DE MODULADORES RECEPTORES DE PEPTìDEO. A presente invenção fornece processo útil para a preparação de intermediários que são úteis na preparação de aminoácidos úteis na preparação de moduladores receptores de peptídeo, por exemplo, agonistas ou agonistas parciais de tais receptores de peptídeo. Tais moduladores receptores de peptídeo incluem, por exemplo, moduladores receptores de peptídeo-1 como glucagon que são úteis para a melhoria da condição diabética.
BRPI0512935-4A 2004-07-02 2005-07-01 processo para a preparação de aminoácido úteis na preparação de moduladores receptores de peptìdeo BRPI0512935A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58496804P 2004-07-02 2004-07-02
PCT/US2005/023363 WO2006014324A1 (en) 2004-07-02 2005-07-01 Process for the preparation of amino acids useful in the preparation of peptide receptor modulators

Publications (1)

Publication Number Publication Date
BRPI0512935A true BRPI0512935A (pt) 2008-04-15

Family

ID=35787400

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0512935-4A BRPI0512935A (pt) 2004-07-02 2005-07-01 processo para a preparação de aminoácido úteis na preparação de moduladores receptores de peptìdeo

Country Status (17)

Country Link
US (1) US7145040B2 (pt)
EP (1) EP1765835A4 (pt)
JP (1) JP2008505180A (pt)
KR (1) KR20070035058A (pt)
CN (1) CN101010325A (pt)
AR (1) AR049663A1 (pt)
AU (1) AU2005270067A1 (pt)
BR (1) BRPI0512935A (pt)
CA (1) CA2571918A1 (pt)
IL (1) IL180431A0 (pt)
MX (1) MXPA06015191A (pt)
NO (1) NO20070615L (pt)
PE (1) PE20061006A1 (pt)
RU (1) RU2352573C2 (pt)
TW (1) TW200613250A (pt)
WO (1) WO2006014324A1 (pt)
ZA (1) ZA200700675B (pt)

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HUP0700151A2 (en) * 2001-10-18 2007-05-29 Bristol Myers Squibb Co Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
US7534763B2 (en) 2004-07-02 2009-05-19 Bristol-Myers Squibb Company Sustained release GLP-1 receptor modulators
AR053495A1 (es) * 2005-05-26 2007-05-09 Bristol Myers Squibb Co Moduladores del peptido 1 similar al glucagon humano y su uso en el tratamiento de la diabetes y condiciones relacionadas
WO2007082264A2 (en) * 2006-01-11 2007-07-19 Bristol-Myers Squibb Company Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions
US20100022457A1 (en) * 2006-05-26 2010-01-28 Bristol-Myers Squibb Company Sustained release glp-1 receptor modulators
US20080044326A1 (en) * 2006-07-04 2008-02-21 Esencia Co., Ltd. Sterilizer for baby products
US20120264685A1 (en) 2009-10-22 2012-10-18 Rajesh Bahekar Short chain peptidomimetics based orally active glp 1 agonist and glucagon receptor antagonist
NZ627192A (en) * 2011-12-30 2015-09-25 Dow Agrosciences Llc Methods of producing methyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylate

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Also Published As

Publication number Publication date
CA2571918A1 (en) 2006-02-09
EP1765835A1 (en) 2007-03-28
MXPA06015191A (es) 2007-02-28
RU2352573C2 (ru) 2009-04-20
PE20061006A1 (es) 2006-10-13
RU2007104104A (ru) 2008-08-10
TW200613250A (en) 2006-05-01
WO2006014324A1 (en) 2006-02-09
AU2005270067A1 (en) 2006-02-09
NO20070615L (no) 2007-03-21
JP2008505180A (ja) 2008-02-21
ZA200700675B (en) 2008-09-25
CN101010325A (zh) 2007-08-01
US7145040B2 (en) 2006-12-05
US20060004222A1 (en) 2006-01-05
EP1765835A4 (en) 2009-07-15
KR20070035058A (ko) 2007-03-29
AR049663A1 (es) 2006-08-23
IL180431A0 (en) 2007-06-03

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.