BRPI0510370A - derivados de ácido fenoxi-alquil-carboxìlico no tratamento de doenças inflamatórias - Google Patents

derivados de ácido fenoxi-alquil-carboxìlico no tratamento de doenças inflamatórias

Info

Publication number
BRPI0510370A
BRPI0510370A BRPI0510370-3A BRPI0510370A BRPI0510370A BR PI0510370 A BRPI0510370 A BR PI0510370A BR PI0510370 A BRPI0510370 A BR PI0510370A BR PI0510370 A BRPI0510370 A BR PI0510370A
Authority
BR
Brazil
Prior art keywords
treatment
carboxylic acid
acid derivatives
inflammatory diseases
phenoxyalkyl carboxylic
Prior art date
Application number
BRPI0510370-3A
Other languages
English (en)
Inventor
Charles Smith
Kenneth Walter Locke
Taka Kiyoizumi
Original Assignee
Medicinova Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicinova Inc filed Critical Medicinova Inc
Publication of BRPI0510370A publication Critical patent/BRPI0510370A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

DERIVADOS DE áCIDO FENOXI-ALQUIL-CARBOXìLICO NO TRATAMENTO DE DOENçAS INFLAMATóRIAS. A presente invenção refere-se a um método para tratar cistite intersticial, síndrome de intestino irritável, colite ulcerativa, e outras condições inflamatórias, que compreende: administrar em um paciente necessitado do mesmo uma quantidade eficaz de um composto selecionado a partir de composto 1, seu metabolito 2 e sais ou pró-fármacos farmaceuticamente aceitáveis do mesmo.
BRPI0510370-3A 2004-04-27 2005-04-27 derivados de ácido fenoxi-alquil-carboxìlico no tratamento de doenças inflamatórias BRPI0510370A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56552704P 2004-04-27 2004-04-27
PCT/US2005/014545 WO2005105073A1 (en) 2004-04-27 2005-04-27 Phenoxyalkycarboxylic acid derivatives in the treatment of inflammatory diseases

Publications (1)

Publication Number Publication Date
BRPI0510370A true BRPI0510370A (pt) 2007-11-06

Family

ID=35241416

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510370-3A BRPI0510370A (pt) 2004-04-27 2005-04-27 derivados de ácido fenoxi-alquil-carboxìlico no tratamento de doenças inflamatórias

Country Status (13)

Country Link
US (3) US7429617B2 (pt)
EP (1) EP1744740A4 (pt)
JP (1) JP2007534771A (pt)
KR (1) KR20070058381A (pt)
CN (1) CN101014331A (pt)
AU (1) AU2005237607B2 (pt)
BR (1) BRPI0510370A (pt)
CA (1) CA2564731A1 (pt)
MX (1) MXPA06012564A (pt)
NO (1) NO20065453L (pt)
NZ (1) NZ550809A (pt)
RU (1) RU2388466C2 (pt)
WO (1) WO2005105073A1 (pt)

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DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
DE102005009240A1 (de) 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
RU2435588C2 (ru) * 2005-09-29 2011-12-10 Байер Шеринг Фарма Акциенгезельшафт Ингибиторы фдэ и их комбинации для лечения урологических расстройств
JP2013119550A (ja) * 2011-12-08 2013-06-17 Medicinova Inc 非アルコール性脂肪性肝疾患及び非アルコール性脂肪性肝炎の処置方法
MX358211B (es) * 2012-07-23 2018-08-10 Landsteiner Scient S A De C V Una composición farmacéutica de liberación comprendiendo hidroclorotiazida, losartán y basilato de amlodipino.
US9539265B2 (en) 2013-03-15 2017-01-10 Aihol Corporation Pharmaceutical formulation containing glycosaminoglycan
WO2014142938A1 (en) * 2013-03-15 2014-09-18 Aihol Corporation Pharmaceutical formulation containing glycosaminoglycan
KR102352728B1 (ko) 2013-07-25 2022-01-18 메디시노바, 인크. 트리글리세라이드, 총 콜레스테롤, 및 저밀도 지단백질의 혈중농도를 감소시키는 방법
US20150321989A1 (en) * 2014-05-08 2015-11-12 Medicinova, Inc. Method of treating idiopathic pulmonary fibrosis
US9346754B2 (en) * 2014-05-08 2016-05-24 Medicinova, Inc. Method of treating advanced non-alcoholic steatohepatitis
JP6469727B2 (ja) * 2014-06-02 2019-02-13 メディシノバ・インコーポレイテッドＭｅｄｉｃｉＮｏｖａ， Ｉｎｃ． 線維症の抑制又は治療方法
WO2016085954A1 (en) * 2014-11-26 2016-06-02 Medicinova, Inc. Geranygeranylacetone and analogs thereof and phenoxyalkylcarboxlic acids for treating fibrosis
KR20180011840A (ko) * 2015-06-12 2018-02-02 비샬 자조디아 스와티 방광 출구 폐쇄 및/또는 하부 요로 증상의 치료에서 사용하기 위한 펜토산폴리설페이트나트륨을 포함하는 조성물
WO2018220237A1 (en) * 2017-06-02 2018-12-06 Goodgut Sl Grape skin for use in the treatment of dysbiosis

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US4428935A (en) 1982-05-24 1984-01-31 Pfizer Inc. Penicillanic acid dioxide prodrug
FR2585246A1 (fr) 1985-07-26 1987-01-30 Cortial Procede d'obtention de formes pharmaceutiques solides a liberation prolongee
US4788055A (en) 1985-12-09 1988-11-29 Ciba-Geigy Corporation Resinate sustained release dextromethorphan composition
GB8613689D0 (en) 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
GB8613688D0 (en) 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
US4816264A (en) 1986-06-06 1989-03-28 Warner-Lambert Company Sustained release formulations
US4985585A (en) * 1988-03-07 1991-01-15 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process for their preparations
JPH07116125B2 (ja) * 1988-03-07 1995-12-13 杏林製薬株式会社 フェノキシアルキルカルボン酸誘導体及びその製造法
US4996047A (en) 1988-11-02 1991-02-26 Richardson-Vicks, Inc. Sustained release drug-resin complexes
CA2002492A1 (en) 1988-11-11 1990-05-11 Sandra T. A. Malkowska Pharmaceutical ion exchange resin composition
US5133974A (en) 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
JPH0551359A (ja) * 1991-01-18 1993-03-02 Kyorin Pharmaceut Co Ltd フエノキシアルキルカルボン酸誘導体及びその製造法
US5290812A (en) 1991-01-18 1994-03-01 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process of preparing the same
US6417186B1 (en) * 2000-11-14 2002-07-09 Syntex (U.S.A.) Llc Substituted-phenyl ketone derivatives as IP antagonists
US7064146B2 (en) 2003-06-24 2006-06-20 Medicinova, Inc. Pharmaceutical compositions of isolated orthorhombic crystalline 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid and methods of use
US7060854B2 (en) 2003-06-24 2006-06-13 Medicinova, Inc. Process for making polymorphic form A of 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid

Also Published As

Publication number Publication date
RU2388466C2 (ru) 2010-05-10
US7429617B2 (en) 2008-09-30
AU2005237607B2 (en) 2010-12-16
US8026282B2 (en) 2011-09-27
NO20065453L (no) 2007-01-17
US20050239902A1 (en) 2005-10-27
US20100285074A1 (en) 2010-11-11
RU2006141647A (ru) 2008-06-10
EP1744740A1 (en) 2007-01-24
CN101014331A (zh) 2007-08-08
JP2007534771A (ja) 2007-11-29
US7786169B2 (en) 2010-08-31
WO2005105073A1 (en) 2005-11-10
US20090093545A1 (en) 2009-04-09
CA2564731A1 (en) 2005-11-10
AU2005237607A1 (en) 2005-11-10
EP1744740A4 (en) 2009-06-17
KR20070058381A (ko) 2007-06-08
MXPA06012564A (es) 2007-01-31
NZ550809A (en) 2010-07-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.