BRPI0508874A - derivados de epotilona - Google Patents
derivados de epotilonaInfo
- Publication number
- BRPI0508874A BRPI0508874A BRPI0508874-7A BRPI0508874A BRPI0508874A BR PI0508874 A BRPI0508874 A BR PI0508874A BR PI0508874 A BRPI0508874 A BR PI0508874A BR PI0508874 A BRPI0508874 A BR PI0508874A
- Authority
- BR
- Brazil
- Prior art keywords
- epothilone derivatives
- derivatives
- epothilone
- epotilone
- formula
- Prior art date
Links
- 150000003883 epothilone derivatives Chemical class 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0405898.8A GB0405898D0 (en) | 2004-03-16 | 2004-03-16 | Organic compounds |
| PCT/EP2005/002756 WO2005090335A1 (en) | 2004-03-16 | 2005-03-15 | Epothilone derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0508874A true BRPI0508874A (pt) | 2007-09-04 |
Family
ID=32117793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0508874-7A BRPI0508874A (pt) | 2004-03-16 | 2005-03-15 | derivados de epotilona |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7825141B2 (enExample) |
| EP (3) | EP1730138A1 (enExample) |
| JP (1) | JP2007529455A (enExample) |
| KR (1) | KR20070006773A (enExample) |
| CN (2) | CN101805328A (enExample) |
| AU (1) | AU2005223325B2 (enExample) |
| BR (1) | BRPI0508874A (enExample) |
| CA (1) | CA2556915A1 (enExample) |
| GB (1) | GB0405898D0 (enExample) |
| RU (1) | RU2006136089A (enExample) |
| WO (1) | WO2005090335A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007016046A1 (de) * | 2007-03-30 | 2008-10-23 | Bayer Schering Pharma Aktiengesellschaft | Verfahren zur Herstellung von Epothilonderivaten durch selektive katalytische Epoxidierung |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1440973A3 (de) | 1995-11-17 | 2004-10-20 | Gesellschaft für biotechnologische Forschung mbH (GBF) | Epothilonderivate, Herstellung und Mittel |
| DE19751027A1 (de) | 1996-11-20 | 1998-05-28 | Degussa | Arylsubstituierte aminoacylierte Phosphonsäuren und deren Halbester |
| US6441186B1 (en) | 1996-12-13 | 2002-08-27 | The Scripps Research Institute | Epothilone analogs |
| US6380394B1 (en) * | 1996-12-13 | 2002-04-30 | The Scripps Research Institute | Epothilone analogs |
| IL135590A (en) | 1997-12-04 | 2003-09-17 | Bristol Myers Squibb Co | Process for the reduction of oxiranyl epothilones to olefinic epothilones |
| FR2775187B1 (fr) | 1998-02-25 | 2003-02-21 | Novartis Ag | Utilisation de l'epothilone b pour la fabrication d'une preparation pharmaceutique antiproliferative et d'une composition comprenant l'epothilone b comme agent antiproliferatif in vivo |
| DE19856128A1 (de) | 1998-12-04 | 2000-06-15 | Volkswagen Ag | Verfahren und Einrichtung zum Lesen von Navigationsdaten |
| AU2795000A (en) * | 1998-12-22 | 2000-07-12 | Novartis Ag | Epothilone derivatives and their use as antitumor agents |
| SK287200B6 (sk) | 1999-02-22 | 2010-03-08 | Gesellschaft Fuer Biotechnologische Forschung Mbh (Gbf) | C-21 modifikované epotilóny, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a použitie |
| BR0212107A (pt) | 2001-08-23 | 2004-08-24 | Novartis Ag | Análogos da ciclopropil e da ciclobutil epotilona |
| DK1483251T3 (da) | 2002-03-12 | 2010-04-12 | Bristol Myers Squibb Co | C3-cyano-epothilon-derivater |
| AU2003266961A1 (en) | 2002-08-02 | 2004-02-25 | Novartis Ag | Epothilone derivatives |
-
2004
- 2004-03-16 GB GBGB0405898.8A patent/GB0405898D0/en not_active Ceased
-
2005
- 2005-03-15 EP EP05716085A patent/EP1730138A1/en not_active Withdrawn
- 2005-03-15 CN CN201010150615A patent/CN101805328A/zh active Pending
- 2005-03-15 EP EP10180401A patent/EP2301940A1/en not_active Withdrawn
- 2005-03-15 CA CA002556915A patent/CA2556915A1/en not_active Abandoned
- 2005-03-15 CN CN2005800069311A patent/CN1926133B/zh not_active Expired - Fee Related
- 2005-03-15 KR KR1020067018936A patent/KR20070006773A/ko not_active Withdrawn
- 2005-03-15 WO PCT/EP2005/002756 patent/WO2005090335A1/en not_active Ceased
- 2005-03-15 RU RU2006136089/04A patent/RU2006136089A/ru not_active Application Discontinuation
- 2005-03-15 JP JP2007503276A patent/JP2007529455A/ja not_active Withdrawn
- 2005-03-15 EP EP10160012A patent/EP2213670A3/en not_active Withdrawn
- 2005-03-15 BR BRPI0508874-7A patent/BRPI0508874A/pt not_active IP Right Cessation
- 2005-03-15 US US10/591,921 patent/US7825141B2/en not_active Expired - Fee Related
- 2005-03-15 AU AU2005223325A patent/AU2005223325B2/en not_active Ceased
-
2010
- 2010-09-21 US US12/886,819 patent/US20110009459A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20110009459A1 (en) | 2011-01-13 |
| CA2556915A1 (en) | 2005-09-29 |
| CN1926133B (zh) | 2010-06-23 |
| EP2213670A3 (en) | 2010-11-24 |
| EP2301940A1 (en) | 2011-03-30 |
| CN101805328A (zh) | 2010-08-18 |
| EP2213670A2 (en) | 2010-08-04 |
| AU2005223325B2 (en) | 2009-09-10 |
| RU2006136089A (ru) | 2008-04-27 |
| WO2005090335A1 (en) | 2005-09-29 |
| US20080114040A1 (en) | 2008-05-15 |
| CN1926133A (zh) | 2007-03-07 |
| JP2007529455A (ja) | 2007-10-25 |
| GB0405898D0 (en) | 2004-04-21 |
| KR20070006773A (ko) | 2007-01-11 |
| US7825141B2 (en) | 2010-11-02 |
| EP1730138A1 (en) | 2006-12-13 |
| AU2005223325A1 (en) | 2005-09-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |