BRPI0416574A - tratamento autólogo de disco degenerado com células - Google Patents
tratamento autólogo de disco degenerado com célulasInfo
- Publication number
- BRPI0416574A BRPI0416574A BRPI0416574-8A BRPI0416574A BRPI0416574A BR PI0416574 A BRPI0416574 A BR PI0416574A BR PI0416574 A BRPI0416574 A BR PI0416574A BR PI0416574 A BRPI0416574 A BR PI0416574A
- Authority
- BR
- Brazil
- Prior art keywords
- autologous treatment
- cell disc
- autologous
- degenerated cell
- disc
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G23/00—Compounds of titanium
- C01G23/04—Oxides; Hydroxides
- C01G23/047—Titanium dioxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/33—Fibroblasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J21/00—Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
- B01J21/06—Silicon, titanium, zirconium or hafnium; Oxides or hydroxides thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
- B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
Abstract
"TRATAMENTO AUTóLOGO DE DISCO DEGENERADO COM CéLULAS". A presente invenção refere-se à administração de células não-cultivadas autólogas dentro de um disco intervertebral doente.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71455903A | 2003-11-13 | 2003-11-13 | |
US10/714,594 US8273347B2 (en) | 2003-05-13 | 2003-11-14 | Autologous treatment of degenerated disc with cells |
PCT/US2004/037500 WO2005049055A1 (en) | 2003-11-13 | 2004-11-11 | Autologous treatment of degenerated disc with cells |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0416574A true BRPI0416574A (pt) | 2007-01-30 |
Family
ID=34623333
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0416574-8A BRPI0416574A (pt) | 2003-11-13 | 2004-11-11 | tratamento autólogo de disco degenerado com células |
Country Status (8)
Country | Link |
---|---|
US (2) | US8273347B2 (pt) |
EP (1) | EP1687010B1 (pt) |
JP (1) | JP2007511515A (pt) |
KR (1) | KR20060130040A (pt) |
BR (1) | BRPI0416574A (pt) |
CA (1) | CA2545912A1 (pt) |
ES (1) | ES2446100T3 (pt) |
WO (1) | WO2005049055A1 (pt) |
Families Citing this family (43)
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US20040054414A1 (en) | 2002-09-18 | 2004-03-18 | Trieu Hai H. | Collagen-based materials and methods for augmenting intervertebral discs |
US7744651B2 (en) | 2002-09-18 | 2010-06-29 | Warsaw Orthopedic, Inc | Compositions and methods for treating intervertebral discs with collagen-based materials |
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US7429378B2 (en) * | 2003-05-13 | 2008-09-30 | Depuy Spine, Inc. | Transdiscal administration of high affinity anti-MMP inhibitors |
US7553827B2 (en) * | 2003-08-13 | 2009-06-30 | Depuy Spine, Inc. | Transdiscal administration of cycline compounds |
US7344716B2 (en) | 2003-05-13 | 2008-03-18 | Depuy Spine, Inc. | Transdiscal administration of specific inhibitors of pro-inflammatory cytokines |
US20040229878A1 (en) * | 2003-05-13 | 2004-11-18 | Depuy Spine, Inc. | Transdiscal administration of specific inhibitors of P38 kinase |
US8273347B2 (en) | 2003-05-13 | 2012-09-25 | Depuy Spine, Inc. | Autologous treatment of degenerated disc with cells |
US8361467B2 (en) * | 2003-07-30 | 2013-01-29 | Depuy Spine, Inc. | Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints |
US8895540B2 (en) | 2003-11-26 | 2014-11-25 | DePuy Synthes Products, LLC | Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor |
US8715733B2 (en) | 2004-07-23 | 2014-05-06 | DePuy Synthes Products, LLC | Enhanced adipose tissue |
US7399742B2 (en) | 2004-07-23 | 2008-07-15 | Depuy Spine, Inc. | Anti-osteolytic therapy involving adiponectin |
BRPI0513834A (pt) * | 2004-07-27 | 2008-05-20 | Synthes Gmbh | método para substituir ou suplementar um núcleo polposo em um disco intervertebral, e, implante restaurador para um disco intervertebral |
KR101447290B1 (ko) | 2004-12-17 | 2014-10-06 | 메르크 파텐트 게엠베하 | 액정 시스템 및 액정 디스플레이 |
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CN102389344B (zh) * | 2006-02-07 | 2015-12-16 | 脊柱赛特有限公司 | 采用机械应变使人皮肤成纤维细胞发生软骨形成分化的方法 |
US8734827B2 (en) * | 2006-04-28 | 2014-05-27 | University Of Hong Kong | Bioengineered intervertebral discs and methods for their preparation |
US9598673B2 (en) | 2006-05-19 | 2017-03-21 | Creative Medical Health | Treatment of disc degenerative disease |
US8399619B2 (en) | 2006-06-30 | 2013-03-19 | Warsaw Orthopedic, Inc. | Injectable collagen material |
US8118779B2 (en) | 2006-06-30 | 2012-02-21 | Warsaw Orthopedic, Inc. | Collagen delivery device |
US9095562B2 (en) * | 2007-07-05 | 2015-08-04 | Regenerative Sciences, Inc. | Methods and compositions for optimized expansion and implantation of mesenchymal stem cells |
CN101945994A (zh) * | 2007-12-19 | 2011-01-12 | 再生科学有限责任公司 | 促进干细胞移植和植入的组合物和方法 |
US20090162351A1 (en) * | 2007-12-21 | 2009-06-25 | Depuy Spine, Inc. | Transdiscal administration of inhibitors of p38 MAP kinase |
US8986696B2 (en) | 2007-12-21 | 2015-03-24 | Depuy Mitek, Inc. | Trans-capsular administration of p38 map kinase inhibitors into orthopedic joints |
US20110052533A1 (en) * | 2008-03-14 | 2011-03-03 | Regenerative Sciences, Llc | Compositions and Methods for Cartilage Repair |
SG10201507149RA (en) * | 2008-06-25 | 2015-10-29 | Mesoblast Inc | Repair and/or Reconstitution of Invertebral Discs |
KR20120006481A (ko) | 2008-12-05 | 2012-01-18 | 리제너러티브 사이언시즈, 엘엘씨 | 무혈관 조직의 복구를 촉진하기 위한 방법 및 조성물 |
US20100168022A1 (en) * | 2008-12-11 | 2010-07-01 | Centeno Christopher J | Use of In-Vitro Culture to Design or Test Personalized Treatment Regimens |
US20110054929A1 (en) * | 2009-09-01 | 2011-03-03 | Cell Solutions Colorado Llc | Stem Cell Marketplace |
US9113950B2 (en) | 2009-11-04 | 2015-08-25 | Regenerative Sciences, Llc | Therapeutic delivery device |
WO2011122601A1 (ja) * | 2010-03-30 | 2011-10-06 | 学校法人東海大学 | 椎間板髄核幹/前駆細胞、その培養方法および用途 |
ES2803499T3 (es) | 2011-06-29 | 2021-01-27 | Biorestorative Therapies Inc | Composiciones y métodos de células grasas marrones |
ES2653679T3 (es) * | 2011-11-09 | 2018-02-08 | Spinalcyte, Llc | Fibroblastos dérmicos para el tratamiento de enfermedad discal degenerativa |
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US9114190B2 (en) | 2013-02-08 | 2015-08-25 | Laser Spine Institute, Llc | Regeneration of spinal discs |
US9314487B2 (en) * | 2013-05-17 | 2016-04-19 | Stemnion, Inc. | Methods for treating cartilage disorders, diseases, and injuries |
US10206954B2 (en) | 2013-06-19 | 2019-02-19 | Spinalcyte, Llc | Adipose cells for chondrocyte applications |
WO2015035395A1 (en) | 2013-09-09 | 2015-03-12 | Figene, Llc | Gene therapy for the regeneration of chondrocytes or cartilage type cells |
US11554195B2 (en) | 2015-06-22 | 2023-01-17 | Cedars-Sinai Medical Center | Method for regenerating the interverterbral disc with notochordal cells |
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US20210154230A1 (en) * | 2018-05-04 | 2021-05-27 | Spinalcyte, Llc | Intradiscal t-regulatory cell administration for treatment of disc degenerative disease |
SG11202106794WA (en) * | 2019-01-02 | 2021-07-29 | Mesoblast Int Sarl | Method for treating lower back pain |
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-
2003
- 2003-11-14 US US10/714,594 patent/US8273347B2/en not_active Expired - Fee Related
-
2004
- 2004-11-11 KR KR1020067009436A patent/KR20060130040A/ko not_active Application Discontinuation
- 2004-11-11 CA CA002545912A patent/CA2545912A1/en not_active Abandoned
- 2004-11-11 BR BRPI0416574-8A patent/BRPI0416574A/pt not_active Application Discontinuation
- 2004-11-11 ES ES04810667.8T patent/ES2446100T3/es active Active
- 2004-11-11 EP EP04810667.8A patent/EP1687010B1/en not_active Not-in-force
- 2004-11-11 JP JP2006539804A patent/JP2007511515A/ja active Pending
- 2004-11-11 WO PCT/US2004/037500 patent/WO2005049055A1/en active Application Filing
-
2008
- 2008-10-31 US US12/291,016 patent/US8333960B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
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US20040229786A1 (en) | 2004-11-18 |
JP2007511515A (ja) | 2007-05-10 |
ES2446100T3 (es) | 2014-03-06 |
US8333960B2 (en) | 2012-12-18 |
WO2005049055A1 (en) | 2005-06-02 |
CA2545912A1 (en) | 2005-06-02 |
EP1687010B1 (en) | 2013-12-25 |
US8273347B2 (en) | 2012-09-25 |
EP1687010A1 (en) | 2006-08-09 |
KR20060130040A (ko) | 2006-12-18 |
US20090068270A1 (en) | 2009-03-12 |
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