BRPI0414857A - dmbt1 como um marcador clìnico e seu uso - Google Patents
dmbt1 como um marcador clìnico e seu usoInfo
- Publication number
- BRPI0414857A BRPI0414857A BRPI0414857-6A BRPI0414857A BRPI0414857A BR PI0414857 A BRPI0414857 A BR PI0414857A BR PI0414857 A BRPI0414857 A BR PI0414857A BR PI0414857 A BRPI0414857 A BR PI0414857A
- Authority
- BR
- Brazil
- Prior art keywords
- dmbt1
- compound
- determining
- estrogen
- regulatory sequence
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/362—Menopause
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
"DMBT1 COMO UM MARCADOR CLìNICO E SEU USO". A presente invenção fornece métodos para determinar a atividade estrogênica de um composto, enquanto inclui contatar um sistema responsivo ao estrogênio tendo um gene sob o controle de uma seqüência reguladora de DMBT1 com um composto de teste e determinar como o composto de teste afeta a expressão do gene. A invenção fornece ainda a determinação da atividade progestogênica de um composto, que inclui contatar um sistema responsivo ao estrogênio e progesterona tendo um gene sob o controle de uma seqüência reguladora de DMBT1 com uma atividade estrogênica e um composto de teste e determinar como o composto de teste efetua a expressão do gene. Os ácidos nucléicos e os sistemas com base em célula que incluem uma porção da seqüência reguladora de DMBT1 útil para estes métodos também são fornecidos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50848403P | 2003-10-03 | 2003-10-03 | |
PCT/US2004/032353 WO2005033661A2 (en) | 2003-10-03 | 2004-10-01 | Dmbt1 as a clinical marker and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0414857A true BRPI0414857A (pt) | 2007-01-02 |
Family
ID=34421744
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0414857-6A BRPI0414857A (pt) | 2003-10-03 | 2004-10-01 | dmbt1 como um marcador clìnico e seu uso |
Country Status (9)
Country | Link |
---|---|
US (1) | US20050208511A1 (pt) |
EP (1) | EP1680657A2 (pt) |
KR (1) | KR20060076787A (pt) |
CN (1) | CN101072590A (pt) |
AU (1) | AU2004277604A1 (pt) |
BR (1) | BRPI0414857A (pt) |
CA (1) | CA2542021A1 (pt) |
MX (1) | MXPA06003666A (pt) |
WO (1) | WO2005033661A2 (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060184198A1 (en) * | 2005-01-31 | 2006-08-17 | Kms Biopsy, Llc | End effector for surgical instrument, surgical instrument, and method for forming the end effector |
CN113801889B (zh) * | 2021-09-18 | 2023-04-07 | 中国农业科学院农业质量标准与检测技术研究所 | 细胞筛选模型及其构建方法和应用、酵母菌及其制备方法和应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998012313A1 (fr) * | 1996-09-20 | 1998-03-26 | Suntory Limited | Procede de tri de composes regulateurs de l'expression de la synthase induisant chez l'homme la production d'acide nitrique |
US6673549B1 (en) * | 2000-10-12 | 2004-01-06 | Incyte Corporation | Genes expressed in C3A liver cell cultures treated with steroids |
-
2004
- 2004-10-01 CN CNA2004800354744A patent/CN101072590A/zh active Pending
- 2004-10-01 BR BRPI0414857-6A patent/BRPI0414857A/pt not_active IP Right Cessation
- 2004-10-01 EP EP04793968A patent/EP1680657A2/en not_active Ceased
- 2004-10-01 KR KR1020067008345A patent/KR20060076787A/ko not_active Application Discontinuation
- 2004-10-01 AU AU2004277604A patent/AU2004277604A1/en not_active Abandoned
- 2004-10-01 CA CA002542021A patent/CA2542021A1/en not_active Abandoned
- 2004-10-01 WO PCT/US2004/032353 patent/WO2005033661A2/en active Application Filing
- 2004-10-01 US US10/957,405 patent/US20050208511A1/en not_active Abandoned
- 2004-10-01 MX MXPA06003666A patent/MXPA06003666A/es unknown
Also Published As
Publication number | Publication date |
---|---|
WO2005033661A2 (en) | 2005-04-14 |
WO2005033661A3 (en) | 2007-07-19 |
CN101072590A (zh) | 2007-11-14 |
EP1680657A2 (en) | 2006-07-19 |
AU2004277604A1 (en) | 2005-04-14 |
MXPA06003666A (es) | 2006-08-31 |
KR20060076787A (ko) | 2006-07-04 |
US20050208511A1 (en) | 2005-09-22 |
CA2542021A1 (en) | 2005-04-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 4A, 5A, 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |