BRPI0410784A - métodos e composições para tratar distúrbios oculares - Google Patents
métodos e composições para tratar distúrbios ocularesInfo
- Publication number
- BRPI0410784A BRPI0410784A BRPI0410784-5A BRPI0410784A BRPI0410784A BR PI0410784 A BRPI0410784 A BR PI0410784A BR PI0410784 A BRPI0410784 A BR PI0410784A BR PI0410784 A BRPI0410784 A BR PI0410784A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- eye
- clostridial
- compositions
- disorder
- Prior art date
Links
- 208000030533 eye disease Diseases 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- 241001112695 Clostridiales Species 0.000 abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 231100001102 clostridial toxin Toxicity 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241001112696 Clostridia Species 0.000 abstract 1
- 206010010741 Conjunctivitis Diseases 0.000 abstract 1
- 206010010755 Conjunctivitis viral Diseases 0.000 abstract 1
- 208000001344 Macular Edema Diseases 0.000 abstract 1
- 206010025415 Macular oedema Diseases 0.000 abstract 1
- 208000003217 Tetany Diseases 0.000 abstract 1
- 206010046851 Uveitis Diseases 0.000 abstract 1
- 208000005914 Viral Conjunctivitis Diseases 0.000 abstract 1
- 201000007032 bacterial conjunctivitis Diseases 0.000 abstract 1
- 201000001891 corneal deposit Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000002538 fungal effect Effects 0.000 abstract 1
- 238000002513 implantation Methods 0.000 abstract 1
- 201000010230 macular retinal edema Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/442,590 US7220422B2 (en) | 2003-05-20 | 2003-05-20 | Methods and compositions for treating eye disorders |
| PCT/US2004/016456 WO2004112830A2 (en) | 2003-05-20 | 2004-05-17 | Clostridial toxins for treating eye disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0410784A true BRPI0410784A (pt) | 2006-06-20 |
Family
ID=33450241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0410784-5A BRPI0410784A (pt) | 2003-05-20 | 2004-05-17 | métodos e composições para tratar distúrbios oculares |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US7220422B2 (enExample) |
| EP (1) | EP1628678A2 (enExample) |
| JP (2) | JP2006528703A (enExample) |
| AU (1) | AU2004249132A1 (enExample) |
| BR (1) | BRPI0410784A (enExample) |
| CA (1) | CA2526427A1 (enExample) |
| WO (1) | WO2004112830A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7341843B2 (en) * | 2003-04-11 | 2008-03-11 | Allergan, Inc. | Botulinum toxin A peptides and methods of predicting and reducing immunoresistance to botulinum toxin therapy |
| US7220422B2 (en) * | 2003-05-20 | 2007-05-22 | Allergan, Inc. | Methods and compositions for treating eye disorders |
| US20050244365A1 (en) * | 2004-05-03 | 2005-11-03 | Novaflux Biosciences, Inc. | Methods, compositions, formulations, and uses of cellulose and acrylic-based polymers |
| US7514088B2 (en) * | 2005-03-15 | 2009-04-07 | Allergan, Inc. | Multivalent Clostridial toxin derivatives and methods of their use |
| US7811584B2 (en) * | 2004-06-30 | 2010-10-12 | Allergan, Inc. | Multivalent clostridial toxins |
| ATE416191T1 (de) | 2004-09-01 | 2008-12-15 | Allergan Inc | Abbaubare clostridientoxine |
| US8343929B2 (en) | 2004-09-23 | 2013-01-01 | Toxcure, Inc. | Treating neoplasms with neurotoxin |
| WO2006101809A1 (en) | 2005-03-15 | 2006-09-28 | Allergan, Inc. | Modified clostridial toxins with enhanced targeting capabilities for endogenous clostridial toxin receptor systems |
| US20080063732A1 (en) * | 2006-07-31 | 2008-03-13 | Hantash Basil M | Method of increasing the efficacy of neurotoxin |
| US9044477B2 (en) * | 2007-12-12 | 2015-06-02 | Allergan, Inc. | Botulinum toxin formulation |
| US9161970B2 (en) | 2007-12-12 | 2015-10-20 | Allergan, Inc. | Dermal filler |
| CA2889514A1 (en) * | 2008-11-26 | 2010-06-03 | Toxcure, Inc. | Treating neoplasms with neurotoxins |
| WO2010087983A1 (en) * | 2009-01-29 | 2010-08-05 | Kambiz Thomas Moazed | Method and system for effecting changes in pigmented tissue |
| US9744237B2 (en) * | 2009-01-29 | 2017-08-29 | Kambiz Thomas Moazed | Method and system for effecting changes in pigmented tissue |
| KR101135486B1 (ko) * | 2011-05-25 | 2012-04-13 | 함종욱 | 보툴리눔 에이형 독소의 액상제품 |
| US9393291B2 (en) * | 2012-04-12 | 2016-07-19 | Botulinum Toxin Research Associates, Inc. | Use of botulinum toxin for the treatment of cerebrovascular disease, renovascular and retinovascular circulatory beds |
| EP2649984A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis |
| EP2649983A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (II) |
| US10035820B2 (en) | 2012-04-13 | 2018-07-31 | Lubrizol Advanced Materials, Inc | Compounds which inhibit neuronal exocytosis |
| EP2649985A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (III) |
| US9005628B2 (en) | 2012-10-04 | 2015-04-14 | Dublin City University | Biotherapy for pain |
| GB201312317D0 (en) | 2013-07-09 | 2013-08-21 | Syntaxin Ltd | Cationic neurotoxins |
| US9216210B2 (en) | 2013-12-23 | 2015-12-22 | Dublin City University | Multiprotease therapeutics for chronic pain |
| US11484580B2 (en) * | 2014-07-18 | 2022-11-01 | Revance Therapeutics, Inc. | Topical ocular preparation of botulinum toxin for use in ocular surface disease |
| US9901627B2 (en) | 2014-07-18 | 2018-02-27 | Revance Therapeutics, Inc. | Topical ocular preparation of botulinum toxin for use in ocular surface disease |
| ES2873479T3 (es) | 2015-01-09 | 2021-11-03 | Ipsen Bioinnovation Ltd | Neurotoxinas catiónicas |
| GB201517450D0 (en) | 2015-10-02 | 2015-11-18 | Ipsen Biopharm Ltd | Method |
| GB201607901D0 (en) | 2016-05-05 | 2016-06-22 | Ipsen Biopharm Ltd | Chimeric neurotoxins |
| EP3263710A1 (en) | 2016-07-01 | 2018-01-03 | Ipsen Biopharm Limited | Production of activated clostridial neurotoxins |
| WO2018060351A1 (en) | 2016-09-29 | 2018-04-05 | Ipsen Biopharm Limited | Hybrid neurotoxins |
| US11123411B2 (en) | 2016-12-08 | 2021-09-21 | Gary E. Borodic | Method of treating macular degeneration using botulinum toxin-based pharmaceuticals |
| US11096993B2 (en) | 2016-12-08 | 2021-08-24 | Gary E. Borodic | Method of treating macular degeneration using botulinum toxin-based pharmaceuticals |
| EP3758611B1 (en) | 2018-02-26 | 2024-07-24 | Ipsen Biopharm Limited | Ultrasound apparatus to guide injection of non-cytotoxic protease |
| GB201909680D0 (en) * | 2019-07-05 | 2019-08-21 | Malvern Cosmeceutics Ltd | Hypercoiling polymer derivatives |
| GB202003813D0 (en) * | 2020-03-16 | 2020-04-29 | Ipsen Biopharm Ltd | Treatment of upper facial lines |
| GB202103372D0 (en) | 2021-03-11 | 2021-04-28 | Ipsen Biopharm Ltd | Modified clostridial neurotoxins |
| AU2023334140A1 (en) * | 2022-08-31 | 2025-03-13 | Evolus, Inc. | Neurotoxin compositions with increased efficacy and effect duration |
| GB202318884D0 (en) | 2023-12-11 | 2024-01-24 | Ipsen Biopharm Ltd | Formulation |
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-
2003
- 2003-05-20 US US10/442,590 patent/US7220422B2/en not_active Expired - Fee Related
-
2004
- 2004-05-17 EP EP04753309A patent/EP1628678A2/en not_active Withdrawn
- 2004-05-17 BR BRPI0410784-5A patent/BRPI0410784A/pt not_active IP Right Cessation
- 2004-05-17 AU AU2004249132A patent/AU2004249132A1/en not_active Abandoned
- 2004-05-17 CA CA002526427A patent/CA2526427A1/en not_active Abandoned
- 2004-05-17 JP JP2006533409A patent/JP2006528703A/ja active Pending
- 2004-05-17 WO PCT/US2004/016456 patent/WO2004112830A2/en not_active Ceased
-
2007
- 2007-04-19 US US11/737,641 patent/US7465458B2/en not_active Expired - Fee Related
-
2008
- 2008-11-14 US US12/271,573 patent/US20090087459A1/en not_active Abandoned
-
2009
- 2009-12-28 US US12/648,260 patent/US20100098727A1/en not_active Abandoned
-
2012
- 2012-02-03 JP JP2012021705A patent/JP2012107034A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US7465458B2 (en) | 2008-12-16 |
| US20040234532A1 (en) | 2004-11-25 |
| US7220422B2 (en) | 2007-05-22 |
| WO2004112830A3 (en) | 2005-03-03 |
| AU2004249132A1 (en) | 2004-12-29 |
| EP1628678A2 (en) | 2006-03-01 |
| US20100098727A1 (en) | 2010-04-22 |
| WO2004112830A2 (en) | 2004-12-29 |
| US20080199498A1 (en) | 2008-08-21 |
| CA2526427A1 (en) | 2004-12-29 |
| JP2006528703A (ja) | 2006-12-21 |
| JP2012107034A (ja) | 2012-06-07 |
| US20090087459A1 (en) | 2009-04-02 |
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