BRPI0407511A - ésteres de polietilenoglicol ativados - Google Patents

ésteres de polietilenoglicol ativados

Info

Publication number
BRPI0407511A
BRPI0407511A BRPI0407511-0A BRPI0407511A BRPI0407511A BR PI0407511 A BRPI0407511 A BR PI0407511A BR PI0407511 A BRPI0407511 A BR PI0407511A BR PI0407511 A BRPI0407511 A BR PI0407511A
Authority
BR
Brazil
Prior art keywords
polyethylene glycol
esters
oxalate
active
activated
Prior art date
Application number
BRPI0407511-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Foe Siong Tjoeng
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of BRPI0407511A publication Critical patent/BRPI0407511A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Polyethers (AREA)
  • Polyesters Or Polycarbonates (AREA)
BRPI0407511-0A 2003-02-19 2004-02-13 ésteres de polietilenoglicol ativados BRPI0407511A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44835403P 2003-02-19 2003-02-19
PCT/IB2004/000424 WO2004074345A2 (en) 2003-02-19 2004-02-13 Carbonate esters of polyethylene glycol activated by means of oxalate esters

Publications (1)

Publication Number Publication Date
BRPI0407511A true BRPI0407511A (pt) 2006-02-14

Family

ID=32908577

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0407511-0A BRPI0407511A (pt) 2003-02-19 2004-02-13 ésteres de polietilenoglicol ativados

Country Status (9)

Country Link
US (1) US7094872B2 (enExample)
EP (1) EP1597299A2 (enExample)
JP (1) JP2006517995A (enExample)
AR (1) AR043216A1 (enExample)
BR (1) BRPI0407511A (enExample)
CA (1) CA2515612A1 (enExample)
MX (1) MXPA05008785A (enExample)
TW (1) TW200426155A (enExample)
WO (1) WO2004074345A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60041715D1 (de) 1999-12-22 2009-04-16 Nektar Therapeutics Al Corp Verfahren zur herstellung von 1-benzotriazolcarbonatestern von wasserlöslichen polymeren
ES2291613T3 (es) * 2002-01-16 2008-03-01 Biocompatibles Uk Limited Conjugados de polimeros.
GB0301014D0 (en) * 2003-01-16 2003-02-19 Biocompatibles Ltd Conjugation reactions
ITPD20040159A1 (it) * 2004-06-21 2004-09-21 Univ Degli Studi Trieste Derivati bifunzionali del polietilenglicole loro preparazione e uso.
US8133707B2 (en) * 2006-01-17 2012-03-13 Enzon Pharmaceuticals, Inc. Methods of preparing activated polymers having alpha nitrogen groups
JP2007209543A (ja) * 2006-02-09 2007-08-23 Hidetoshi Tsuchida 表面修飾アルブミンからなる固相膜および酸素吸着膜
JP2009533347A (ja) 2006-04-07 2009-09-17 ネクター セラピューティックス エイエル,コーポレイション 抗TNFα抗体の複合体

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
US5618697A (en) * 1982-12-10 1997-04-08 Novo Nordisk A/S Process for preparing a desired protein
US5122614A (en) * 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
CA2102808A1 (en) * 1991-05-10 1992-11-11 Hanne Bentz Targeted delivery of bone growth factors
US5281698A (en) * 1991-07-23 1994-01-25 Cetus Oncology Corporation Preparation of an activated polymer ester for protein conjugation
US5382657A (en) * 1992-08-26 1995-01-17 Hoffmann-La Roche Inc. Peg-interferon conjugates
US5650234A (en) * 1994-09-09 1997-07-22 Surface Engineering Technologies, Division Of Innerdyne, Inc. Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces
US5932462A (en) * 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
US6180095B1 (en) * 1997-12-17 2001-01-30 Enzon, Inc. Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
GB0013810D0 (en) * 2000-06-06 2000-07-26 Celltech Chiroscience Ltd Biological products

Also Published As

Publication number Publication date
EP1597299A2 (en) 2005-11-23
CA2515612A1 (en) 2004-09-02
JP2006517995A (ja) 2006-08-03
MXPA05008785A (es) 2005-10-18
WO2004074345A2 (en) 2004-09-02
WO2004074345A3 (en) 2005-01-20
US7094872B2 (en) 2006-08-22
TW200426155A (en) 2004-12-01
US20040162388A1 (en) 2004-08-19
AR043216A1 (es) 2005-07-20

Similar Documents

Publication Publication Date Title
ID26984A (id) Senyawa-senyawa sulfonamida sebagai antagonis reseptor angiotensin endotelin ganda
BR0316670A (pt) Anticorpos quiméricos e humanizados para integrina (alfa)5ß1 que modulam a angiogênese
DE69428521D1 (de) Arzneizusammensetzungen enthaltend ein bakterizides permeabilität erhöhendes protein und ein tensid
BR0112101A (pt) Interleucina 2 estabilizada
BRPI0515760A (pt) proteìnas de fusão
BR9807098A (pt) Antagonistas de endotelina: n[[2'-[[(4,5-dimetil-3-isoxazolil)amino]sulfonil]-4-(2-oxa zolil)[1,1'-bi-fenil]-2-il]-n,3,3-trimetilbutanamida e n-(4,5-dimetil-3-isoxazolil)-2'-[(3,3-dimetil-2-oxo-1-pirro lidinil) metil]-4'-2-oxazolil)[1,1' -bifenil]-2-sulfonamida e sais dos mesmos
BR0009206A (pt) Isolamento e análise de proteina
WO2001044239A3 (en) Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
BR0014486A (pt) Composições farmacêuticas contendo polipeptìdeo lìquido estabilizado
NO20033918L (no) Ny anvendelse av peptidklasse av forbindelser for behandling av allodyni eller andre typer av kronisk smerte eller fantomsmerte
ATE345133T1 (de) Laktose-freie, nicht-hygroskopische und wasserfreie pharmazeutische zusammensetzungen von descarboethoxyloratadin
DE50112802D1 (de) Peptide, deren herstellung und verwendung zur bindung von immunglobulinen
AR051512A1 (es) Proteina de fusion que comprende un dominio bh3 de una proteina "solo bh3"
BRPI0407511A (pt) ésteres de polietilenoglicol ativados
BRPI0407533A (pt) proteìnas de fusão e muteìnas do interferon alfa com propriedades melhoradas
ES2422081T3 (es) Péptido Ser-Ser-Ser-Arg y sus utilizaciones medicinales
BR0009472A (pt) Antagonistas de lhrh com propriedades desolubilidade aperfeiçoadas
ATE356140T1 (de) Gd3 mimetische peptide
BR0210428A (pt) Uso de glicoproteìna para preparação de composições para o tratamento e a reepitelização de feridas
BR0109279A (pt) Antagonistas de lhrh, sua preparação e aplicação como medicamento
WO2004056384A3 (en) Use of factor vii polypeptides for preventing formation of inhibitors to blood coagulation factor viii and ix
BR9809457A (pt) Sais de peptìdeo de bpc com atividade organo-protetora, o processo para sua preparação e seu uso em terapia.
BR9814433A (pt) "beta-lipotropina e usos da mesma"
BR9810387A (pt) (s) 3, 4, 5-trimetoxibenzoato de 2-metilamino-2-fenil-n-butila, e sua aplicação para o tratamento de dor crÈnica
ATE299704T1 (de) Warmgeformte feste arzneizusammensetzung zur gesteuerten wirkstoffabgabe von perindopril

Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.

B15K Others concerning applications: alteration of classification

Ipc: A61K 47/60 (2017.01), A61P 5/08 (2006.01), A61P 29