BRPI0407341A - Combinação de drogas antidiabéticas - Google Patents

Combinação de drogas antidiabéticas

Info

Publication number
BRPI0407341A
BRPI0407341A BR0407341-0A BRPI0407341A BRPI0407341A BR PI0407341 A BRPI0407341 A BR PI0407341A BR PI0407341 A BRPI0407341 A BR PI0407341A BR PI0407341 A BRPI0407341 A BR PI0407341A
Authority
BR
Brazil
Prior art keywords
combination
drug combination
antidiabetic drug
drugs
antidiabetic
Prior art date
Application number
BR0407341-0A
Other languages
English (en)
Inventor
Pompeo Pessotto
Fabio Giannessi
Original Assignee
Sigma Tau Ind Famaceutiche Riu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Famaceutiche Riu filed Critical Sigma Tau Ind Famaceutiche Riu
Publication of BRPI0407341A publication Critical patent/BRPI0407341A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"COMBINAçãO DE DROGAS ANTIDIABéTICAS". A presente invenção refere-se a combinação de R-4-trimetilamónio-3-(tetradecilcarbamoil)-aminobutirato e metformina. A referida combinação de drogas antidiabéticas exerce uma ação sinérgica e permite a administração das duas drogas em doses tais como para evitar ou reduzir a ocorrência de efeitos colaterais. A combinação também é útil para aperfeiçoar a cobertura terapêutica longe dos horários das refeições, e na pós-absorção e condições de jejum.
BR0407341-0A 2003-02-10 2004-01-23 Combinação de drogas antidiabéticas BRPI0407341A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000053A ITRM20030053A1 (it) 2003-02-10 2003-02-10 Associazione di farmaci antidiabetici.
PCT/IT2004/000014 WO2004069239A1 (en) 2003-02-10 2004-01-23 Combination of antidiabetic drugs

Publications (1)

Publication Number Publication Date
BRPI0407341A true BRPI0407341A (pt) 2006-01-10

Family

ID=29765650

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0407341-0A BRPI0407341A (pt) 2003-02-10 2004-01-23 Combinação de drogas antidiabéticas

Country Status (22)

Country Link
US (1) US20060058385A1 (pt)
EP (1) EP1592417B1 (pt)
JP (1) JP2006517223A (pt)
KR (1) KR20050098285A (pt)
CN (1) CN1741799B (pt)
AR (1) AR043129A1 (pt)
AT (1) ATE359776T1 (pt)
AU (1) AU2004210246B2 (pt)
BR (1) BRPI0407341A (pt)
CA (1) CA2512618C (pt)
CY (1) CY1106546T1 (pt)
DE (1) DE602004005966T2 (pt)
DK (1) DK1592417T3 (pt)
ES (1) ES2286595T3 (pt)
HK (1) HK1087623A1 (pt)
IT (1) ITRM20030053A1 (pt)
MX (1) MXPA05008336A (pt)
PL (1) PL378419A1 (pt)
PT (1) PT1592417E (pt)
SI (1) SI1592417T1 (pt)
TW (1) TWI322687B (pt)
WO (1) WO2004069239A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101860120B1 (ko) * 2010-05-26 2018-05-23 브이티브이 테라퓨틱스 엘엘씨 글루코키나아제 활성화제와 병용되는 메트포르민의 용도, 및 메트포르민과 글루코키나아제 활성화제를 포함하는 조성물
US8735349B2 (en) * 2011-05-13 2014-05-27 Sanofi-Aventis Deutschland Gmbh Method for improving glucose tolerance in a diabetes type 2 patient of younger than 50 years and having postprandial plasma glucose concentration of at least 14 mmol/L

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1299266B1 (it) * 1998-05-15 2000-02-29 Sigma Tau Ind Farmaceuti Inibitori reversibili della carnitina palmitoil trasferasi

Also Published As

Publication number Publication date
AU2004210246A1 (en) 2004-08-19
AR043129A1 (es) 2005-07-20
JP2006517223A (ja) 2006-07-20
CY1106546T1 (el) 2012-01-25
TWI322687B (en) 2010-04-01
CN1741799B (zh) 2010-05-26
DK1592417T3 (da) 2007-08-06
PL378419A1 (pl) 2006-04-03
CN1741799A (zh) 2006-03-01
PT1592417E (pt) 2007-07-17
AU2004210246B2 (en) 2009-05-07
ITRM20030053A1 (it) 2004-08-11
DE602004005966D1 (de) 2007-05-31
ATE359776T1 (de) 2007-05-15
EP1592417B1 (en) 2007-04-18
DE602004005966T2 (de) 2007-12-20
KR20050098285A (ko) 2005-10-11
SI1592417T1 (sl) 2007-08-31
ITRM20030053A0 (it) 2003-02-10
CA2512618A1 (en) 2004-08-19
MXPA05008336A (es) 2005-11-04
ES2286595T3 (es) 2007-12-01
WO2004069239A1 (en) 2004-08-19
EP1592417A1 (en) 2005-11-09
TW200418450A (en) 2004-10-01
HK1087623A1 (en) 2006-10-20
CA2512618C (en) 2011-12-13
US20060058385A1 (en) 2006-03-16

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08L Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette]

Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 9A E 10A ANUIDADES.

B08I Publication cancelled [chapter 8.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2257 DE 08/04/2014 POR TER SIDO INDEVIDA.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 9A, 10A, 11A, 12A, 13A, 14A, 15A E 16A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.