BRPI0406705A - Policosanóis a partir da cera de ericerus pela - Google Patents

Policosanóis a partir da cera de ericerus pela

Info

Publication number
BRPI0406705A
BRPI0406705A BR0406705-3A BRPI0406705A BRPI0406705A BR PI0406705 A BRPI0406705 A BR PI0406705A BR PI0406705 A BRPI0406705 A BR PI0406705A BR PI0406705 A BRPI0406705 A BR PI0406705A
Authority
BR
Brazil
Prior art keywords
ericerus
wax
composition
aliphatic alcohols
policosanols
Prior art date
Application number
BR0406705-3A
Other languages
English (en)
Inventor
Qi Jia
Ji-Fu Zhao
Original Assignee
Unigen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=30115456&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0406705(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Unigen Pharmaceuticals Inc filed Critical Unigen Pharmaceuticals Inc
Publication of BRPI0406705A publication Critical patent/BRPI0406705A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"POLICOSANóIS A PARTIR DA CERA DE ERICERUS PELA". A presente invenção refere-se um método inovador para a preparação de um perfil singular de álcoois alifáticos primários que têm 24 a 30 átomos de carbono, a partir da cera secretada pelo inseto Ericerus pela. Está incluída na presente invenção a composição de matéria, aqui referida como 'policosanol', produzida pelo método desta invenção. A composição de policosanóis compreende primordialmente os quatro álcoois alifáticos primários, tetracosanol, hexacosanol, octacosanol e triacontanol. Está ainda incluído nesta invenção o uso da dita composição de matéria para a prevenção e o tratamento de obesidade, síndrome X, diabetes, hipercolesterolemia, complicações ateroscleróticas, isquemia e trombose.
BR0406705-3A 2003-01-31 2004-01-27 Policosanóis a partir da cera de ericerus pela BRPI0406705A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/356,676 US6683116B1 (en) 2003-01-31 2003-01-31 Polycosanols from Ericerus pela wax
PCT/US2004/002273 WO2004069161A2 (en) 2003-01-31 2004-01-27 Polycosanols from ericerus pela wax

Publications (1)

Publication Number Publication Date
BRPI0406705A true BRPI0406705A (pt) 2005-12-20

Family

ID=30115456

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0406705-3A BRPI0406705A (pt) 2003-01-31 2004-01-27 Policosanóis a partir da cera de ericerus pela

Country Status (7)

Country Link
US (3) US6683116B1 (pt)
EP (1) EP1589815A4 (pt)
JP (1) JP2006517583A (pt)
KR (1) KR20050094895A (pt)
CN (1) CN100356909C (pt)
BR (1) BRPI0406705A (pt)
WO (1) WO2004069161A2 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004055858A1 (de) * 2004-11-19 2006-05-24 Clariant Gmbh Verwendung von langkettigen Alkoholen zur effektiven Senkung erhöhter Cholesterinspiegel
CN1298688C (zh) * 2004-12-31 2007-02-07 长沙世唯科技有限公司 普利醇的提取制备工艺及其应用
JP5555894B2 (ja) * 2005-03-10 2014-07-23 日油株式会社 脂質代謝調整剤
KR100727396B1 (ko) 2005-04-16 2007-06-13 비타민하우스알앤비티(주) 수박 껍질 추출물 및 옥사코사놀의 혼합물을 함유하는조성물
DE102005045829A1 (de) * 2005-09-24 2007-03-29 Clariant Produkte (Deutschland) Gmbh Mittel enthaltend langkettige Alkohole zur Suppression der Konzentrationen des C-reaktiven Proteins (CRP) im menschlichen Blut
JP2007091672A (ja) * 2005-09-29 2007-04-12 Nof Corp アディポネクチン上昇剤
BRPI0506066A (pt) * 2005-12-13 2007-10-02 Biosintetica Farmaceutica Ltda composição para doença aterosclerótica
MXPA05014086A (es) * 2005-12-20 2007-06-20 Leopoldo De Jesus Espinosa Abdala Composiciones farmaceuticas que comprenden sustancias antiagregantes plaquetarios combinadas para su uso en el tratamiento y prevencion de eventos vasculares de origen isquemico.
TWI348135B (en) 2006-06-05 2011-09-01 Chunghwa Picture Tubes Ltd Image contrast correct system and method thereof
US20120058207A1 (en) 2009-03-24 2012-03-08 Universiti Putra Malaysia Anti-diabetic nutraceutical composition from palm leaf extract
CL2009001166A1 (es) * 2009-05-13 2009-09-04 Pontificia Univ Catolica De Valparaiso Proceso para la obtencion de tetracosanol a partir de una composicion de materia liviana, donde se forma una disolucion contactando la composicion con hexano y calentar, enfriar la disolucion formando una fase solida y liquida, separar la fase solida, y fraccionar por destilacion la fase solida.
US8916031B2 (en) 2009-05-13 2014-12-23 Pontificia Universidad Catolica De Valparaiso Recovery of tetracosanol from a mixture derived from tall oil pitch
KR101328668B1 (ko) * 2010-09-10 2013-11-14 한국식품연구원 비만억제 활성과 혈당강하 효능이 있는 꾸지뽕 및 의이인을 포함하는 조성물 및 이의 용도
FR2987270A1 (fr) * 2012-02-29 2013-08-30 Agronomique Inst Nat Rech Produit de combinaison pour le traitement du surpoids et/ou l'amelioration de la silhouette
KR101492260B1 (ko) * 2013-02-07 2015-02-09 (주)세원씨엔에스 녹차잎으로부터 폴리코사놀 제조방법 및 그 방법으로 제조된 조성물
EP3110781B1 (en) 2014-02-27 2018-06-27 Tydock Pharma S.r.l. Microwave-assisted treatment for the production of polycosanol-enriched mixtures from wax matrices
CN106187677B (zh) * 2016-07-19 2019-03-26 北京颐方生物科技有限公司 一种以蔗蜡制备高级脂肪伯醇混合物的方法及应用
IT202100020228A1 (it) 2021-07-29 2023-01-29 Chromaleont Srl Metodo per l’estrazione di policosanoli da canapa industriale e relativa miscela.
CN115414333A (zh) * 2022-05-31 2022-12-02 湖北中古生物制药有限公司 一种多廿烷醇阿司匹林复方制剂及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6289637A (ja) 1985-05-31 1987-04-24 Seitetsu Kagaku Co Ltd 直鎖第１級脂肪族高級アルコ−ルの抽出法
JPS63133962A (ja) * 1986-11-22 1988-06-06 Nippon Oil & Fats Co Ltd 栄養補助食品
JPH0256442A (ja) * 1988-08-23 1990-02-26 Nippon Oil & Fats Co Ltd 高級アルコールの製造方法
CH681007A5 (pt) * 1990-10-23 1992-12-31 Nestle Sa
CU22229A1 (es) 1992-09-29 1996-01-31 Dalmer Lab Sa Policosanol, una mezcla de alcoholes alifaticos primarios superiores para hipergregabilidad plaquetaria, los accidentes isquemicos, trombosis e incluso efectividad contra ulceras gastricas quimicamente inducidas y su proceso de obtencion de la caña de azucar. el tratamiento de complicaciones ateroscleroticas tales como la
CU22412A1 (es) 1993-11-09 1996-01-31 Dalmer Lab Sa Una mezcla natural compuesta por alcoholes alifaticos primarios superiores obtenidos de la cera de abejas para el tratamiento de las ulceras gastricas y duodenales que presenta tambien actividad antiinflamatoria
US6465526B1 (en) 1994-11-07 2002-10-15 Laboratories Dalmer Sa Natural mixture composed of higher primary aliphatic alcohols obtained from bee wax for the treatment of gastric and duodenal ulcers that also present antiinflamatory activity
CN1125096A (zh) * 1994-12-23 1996-06-26 戴默实验室股份公司 由来自蜂蜡的高级脂肪伯醇组成的天然混合物
GB9806086D0 (en) 1998-03-20 1998-05-20 Woolcombers Group Plc Product and method of isolating same
US6225354B1 (en) * 1999-06-21 2001-05-01 Cholesterol Control Laboratories, Inc. High molecular weight primary aliphatic alcohols obtained from beeswax and pharmaceutical use thereof
IT1320180B1 (it) * 2000-12-29 2003-11-26 Hunza Di Marazzita Maria Carme Preparazioni nutrizionali e terapeutiche dotate di attivita'antiossidante ed in grado di controllare gli eccessi ponderali e

Also Published As

Publication number Publication date
US20050131078A1 (en) 2005-06-16
KR20050094895A (ko) 2005-09-28
WO2004069161A2 (en) 2004-08-19
US6822004B2 (en) 2004-11-23
CN100356909C (zh) 2007-12-26
CN1744816A (zh) 2006-03-08
US6683116B1 (en) 2004-01-27
US20040152787A1 (en) 2004-08-05
US6984666B2 (en) 2006-01-10
EP1589815A4 (en) 2007-10-10
EP1589815A2 (en) 2005-11-02
WO2004069161A3 (en) 2004-12-02
JP2006517583A (ja) 2006-07-27

Similar Documents

Publication Publication Date Title
BRPI0406705A (pt) Policosanóis a partir da cera de ericerus pela
CN107708652B (zh) 芳香剂组合物及其用途
BRPI0513328A (pt) composição, processo de produção da mesma, produto alimentìcio, e, usos de uma composição e de uma combinação de um ou mais álcoois de açúcar e um ou mais açúcares de redução
TW200700012A (en) Oil and fat composition
BRPI0510864A (pt) composição de microemulsão aquosa e processo para preparar uma composição de microemulsão aquosa
BR0312162A (pt) seqüências de ácido nucléico relacionadas com a tioesterase e processos de uso para a produção de plantas com composição modificada de ácidos graxos
ATE515252T1 (de) Pseudokörpergeruchszusammensetzung
BRPI0702263A (pt) composição catalisadora e método de preparação de uma espuma de poliisocianurato/poliuretano
BRPI0519756A2 (pt) produto em tecido e mÉtodo de produzir um produto em tecido
BRPI0609765A8 (pt) mistura de isoalcano, método para a preparação da mesma, composição cosmética ou farmacêutica, e, uso de uma mistura de isoalcano
BRPI0513939A (pt) composição, formador de creme e/ou clareador, composição de alimento, processo para a manufatura de uma composição e uso de uma composição
FI20022129A (fi) Rasvahappokoostumus, sen valmistus ja käyttö
ATE542858T1 (de) Polybutylen-terephthalat-harz-zusammensetzung und dünner geformter artikel daraus
CL2008003413A1 (es) Producto alimenticio que comprende 0,28-0,35% de un agente salivante y un 0,02-0,045% de un agente refrescante en una proporción en peso de 1:0,06 a 10,2; método para mejorar la sensación refrescante de un postre helado que comprende el agente salivante y el agente refrescante; y su uso.
BRPI0715198A8 (pt) Composição de perfume, seu uso, método e artigo adequado para prevenção ou alívio de mau odor da urina, e produtos para consumidores
CO6480911A2 (es) Metodo para producir alimento seco para gatos altamente agradable
EG24034A (en) Foods resistant to changes in flavour due to exposure to light, compositions for imparting such resistance and processes for making said compositions
Ribechini et al. An integrated analytical approach for characterizing an organic residue from an archaeological glass bottle recovered in Pompeii (Naples, Italy)
Ravit et al. Organic compounds associated with microplastic pollutants in New Jersey, USA surface waters
BRPI0510907A (pt) composição em barra e método para realçar as propriedades de formação de espuma
Lorber et al. Influence of the chemical structure on odor qualities and odor thresholds in homologous series of alka-1, 5-dien-3-ones, alk-1-en-3-ones, alka-1, 5-dien-3-ols, and alk-1-en-3-ols
Worzakowska Thermal properties of citronellyl diesters
AR064282A1 (es) Composiciones de aldehido y alcohol derivadas de aceite de semillas
BR0109950A (pt) Composição condimentìcia, alimentos e bebidas, processo para produzi-los, e, método para conferir um sabor melhorado aos mesmos
WO2016098515A1 (ja) シトラスフレーバー含有製品、飲料、香料組成物、劣化臭生成抑制方法および香気劣化抑制方法

Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Free format text: ALTERADO DA INT. CL. A01N 31/00, A61K 31/045.

Ipc: A61K 31/045 (2006.01), A61P 3/00 (2006.01)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal of application maintained [chapter 11.20 patent gazette]