BR9915165A - Genes e proteìnas de virulência e uso dos mesmos - Google Patents

Genes e proteìnas de virulência e uso dos mesmos

Info

Publication number
BR9915165A
BR9915165A BR9915165-0A BR9915165A BR9915165A BR 9915165 A BR9915165 A BR 9915165A BR 9915165 A BR9915165 A BR 9915165A BR 9915165 A BR9915165 A BR 9915165A
Authority
BR
Brazil
Prior art keywords
proteins
genes
virulence genes
virulence
identification
Prior art date
Application number
BR9915165-0A
Other languages
English (en)
Inventor
Helen Rachel Crooke
Enda Elizabeth Clarke
Paul Howardeverest
Gordon Dougan
David William Holden
Jacquelineelizabeth Shea
Robert Graham Feldman
Original Assignee
Microscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9824570.7A external-priority patent/GB9824570D0/en
Priority claimed from GBGB9824569.9A external-priority patent/GB9824569D0/en
Priority claimed from GBGB9827816.1A external-priority patent/GB9827816D0/en
Priority claimed from GBGB9827815.3A external-priority patent/GB9827815D0/en
Priority claimed from GBGB9827814.6A external-priority patent/GB9827814D0/en
Priority claimed from GBGB9827818.7A external-priority patent/GB9827818D0/en
Priority claimed from GBGB9901915.0A external-priority patent/GB9901915D0/en
Application filed by Microscience Ltd filed Critical Microscience Ltd
Publication of BR9915165A publication Critical patent/BR9915165A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/30—Signal or leader sequence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/31—Linker sequence

Abstract

Patente de Invenção: "GENES E PROTEìNAS DE VIRULêNCIAE USO DOS MESMOS". A presente invenção se baseia naidentificação de uma série de genes de virulência em E. coli K1, osprodutos dos quais podem estar implicados na patogenicidade doorganismo. A identificação dos genes lhes permite, ou a seusprodutos expressos, que sejam usados, de inúmeras maneiras, paratratar infecções.
BR9915165-0A 1998-11-09 1999-11-09 Genes e proteìnas de virulência e uso dos mesmos BR9915165A (pt)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
GBGB9824570.7A GB9824570D0 (en) 1998-11-09 1998-11-09 Virulence gene and protein,and their use
GBGB9824569.9A GB9824569D0 (en) 1998-11-09 1998-11-09 Virulence gene and protein,and their use
GBGB9827816.1A GB9827816D0 (en) 1998-12-17 1998-12-17 Virulence gene and protein,and their use
GBGB9827815.3A GB9827815D0 (en) 1998-12-17 1998-12-17 Virulence gene and protein,and their use
GBGB9827814.6A GB9827814D0 (en) 1998-12-17 1998-12-17 Virulence gene and protein and their use
GBGB9827818.7A GB9827818D0 (en) 1998-12-17 1998-12-17 Virulence gene and protein,and their use
GB9900708 1999-01-13
GB9900711 1999-01-13
GB9900710 1999-01-13
GBGB9901915.0A GB9901915D0 (en) 1999-01-28 1999-01-28 Virulence gene and protein,and their use
PCT/GB1999/003721 WO2000028038A2 (en) 1998-11-09 1999-11-09 Virulence genes and proteins, and their use

Publications (1)

Publication Number Publication Date
BR9915165A true BR9915165A (pt) 2001-12-04

Family

ID=27579424

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9915165-0A BR9915165A (pt) 1998-11-09 1999-11-09 Genes e proteìnas de virulência e uso dos mesmos

Country Status (12)

Country Link
US (2) US6846667B1 (pt)
EP (2) EP1129196B1 (pt)
JP (1) JP2002529091A (pt)
KR (1) KR20010099789A (pt)
CN (2) CN1196787C (pt)
AT (1) ATE383425T1 (pt)
AU (1) AU773003B2 (pt)
BR (1) BR9915165A (pt)
CA (1) CA2348699A1 (pt)
DE (1) DE69937965T2 (pt)
NZ (2) NZ527279A (pt)
WO (1) WO2000028038A2 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ511170A (en) * 1994-12-09 2005-02-25 Imp College Innovations Ltd Administering anitgens for protection against Salmonella infections
AU5860599A (en) * 1998-09-04 2000-03-27 Creatogen Aktiengesellschaft Attenuated salmonella spi2 mutants as antigen carriers
GB9910812D0 (en) * 1999-05-10 1999-07-07 Microscience Ltd Vaccine composition
GB0012079D0 (en) * 2000-05-18 2000-07-12 Microscience Ltd Virulence gene and protein, and their use
FR2842210B1 (fr) * 2002-07-09 2012-12-14 Mutabilis Determinants de pathogenicite utilisables comme cibles pour l'elaboration de moyens de prevention et de controle d'infections bacteriennes et/ou de la dissemination systemique
US7078165B2 (en) * 2003-03-27 2006-07-18 Institut Pasteur Method for modulating Nod1 activity, use of a MTP related molecule for modulating Nod1 activity, and therapeutic applications thereof
US8703153B2 (en) 2008-06-16 2014-04-22 Prokarium Ltd. Salmonella vectored vaccines against Chlamydia and methods of use
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN113520895B (zh) * 2021-07-30 2023-05-02 中国科学院大学 一种环保免洗消毒洗手液及其制备方法

Also Published As

Publication number Publication date
EP1914312A3 (en) 2008-10-08
EP1129196A2 (en) 2001-09-05
WO2000028038A2 (en) 2000-05-18
AU773003B2 (en) 2004-05-13
DE69937965D1 (de) 2008-02-21
KR20010099789A (ko) 2001-11-09
DE69937965T2 (de) 2009-01-08
JP2002529091A (ja) 2002-09-10
NZ511366A (en) 2004-03-26
CN1330714A (zh) 2002-01-09
WO2000028038A3 (en) 2000-08-31
CN1196787C (zh) 2005-04-13
AU1060500A (en) 2000-05-29
CA2348699A1 (en) 2000-05-18
EP1129196B1 (en) 2008-01-09
EP1914312A2 (en) 2008-04-23
CN1264568C (zh) 2006-07-19
NZ527279A (en) 2005-05-27
US6846667B1 (en) 2005-01-25
ATE383425T1 (de) 2008-01-15
CN1524575A (zh) 2004-09-01
US20050142149A1 (en) 2005-06-30

Similar Documents

Publication Publication Date Title
ATE172984T1 (de) Nukleinsäuren-bindende oligomere mit n- verzweigung für therapie und diagnostik
CY1112171T1 (el) Μτβ32α αντιγονο μυκοβακτηριδιου της φυματιωσης με απενεργοποιημενη δραστικη θεση και πρωτεϊνες συντηξης αυτου
ES2150496T3 (es) Cicloalquilimidazopiridinas condensadas.
DE68917163T2 (de) Antibakterielle Mittel.
BR0208142A (pt) Combinações compreendendo um agente antidiarréico e epotilona ou derivado de epotilona
PT672658E (pt) Agentes antitromboticos
BR9915165A (pt) Genes e proteìnas de virulência e uso dos mesmos
FI970115A (fi) Nukeliinihappoja sisältävä valmiste, sen valmistus ja käytöt
ATE190357T1 (de) Schnelles verfahren fur die dns sequenzierung und diagnostische anwendungen
NO933077L (no) Anvendelse av IL-4-reseptor for terapi i profylakse og diagnostikk av allergiske, virale og parasitiske og bakterielle sykdommer
ES2171417T3 (es) Uso de aislados de bacillus thuringiensis para controlar plagas de la familia aphididae.
DE69224069D1 (de) Pharmazeutisches kombinationspräparat, das ein uricosurisches mittel und einen excitatorischen aminosäure-antagonisten enthält
ES2116340T3 (es) Emulsiones multiples y metodos de preparacion.
DE69323183D1 (de) Weitere indolderivate mit antiviraler wirkung
DE60126495D1 (de) Nukleinsäure und protein, genannt 158p1d7, für die behandlung und erkennung von blasenkrebs und anderen krebsarten
BR0014663A (pt) Moléculas de ácido nucléico para a detecção de bactérias e unidades filogenéticas de bactérias
DE59408308D1 (de) Nukleinsäure-bindende Oligomere mit C-Verzweigung für Therapie und Diagnostik
FI973221A0 (fi) 1-aryyli-2-asyyliammo-etaaniyhdisteitä ja niiden käyttö neurokiniiniantagonisteina, erityisesti neurokiniini 1 antagonisteina
DE68912020T2 (de) N-2,3-Butadienyl-tri-aminoalkanderivate.
BR9916473A (pt) Proteìnas de superfìcie exterior, seus genes e seu uso
DE69323191T2 (de) Wasserlösliche retinoide
DE60003074D1 (de) Fusidinsäure-derivate
DK0524421T3 (da) Humant herpesvirus type 6 protein p 100, de tilsvarende DNA-sekvenser, deres fremstilling og anvendelse
BR0211533A (pt) Tratamento de dor crÈnica com 3-heterociclil- e 3-cicloalquil-3-ariloxipropanaminas
BR9806851A (pt) ComposiçÊes farmaceuticas e alimenticias que contêm bactérias de gênero acetobacter

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 10 (IX), 24 E 25 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.