BR9910176A - Forma de partìcula de tamanho reduzido de composto, composto, pó, uso de uma substância, e, composição farmacêutica - Google Patents

Forma de partìcula de tamanho reduzido de composto, composto, pó, uso de uma substância, e, composição farmacêutica

Info

Publication number
BR9910176A
BR9910176A BR9910176-9A BR9910176A BR9910176A BR 9910176 A BR9910176 A BR 9910176A BR 9910176 A BR9910176 A BR 9910176A BR 9910176 A BR9910176 A BR 9910176A
Authority
BR
Brazil
Prior art keywords
compost
particle size
substance
pharmaceutical composition
compound
Prior art date
Application number
BR9910176-9A
Other languages
English (en)
Inventor
Marianne Bernice Ashford
Roger James
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR9910176A publication Critical patent/BR9910176A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

''FORMA DE PARTìCULA DE TAMANHO REDUZIDO DE COMPOSTO, COMPOSTO, Pó, USO DE UMA SUBSTâNCIA, E, COMPOSIçãO FARMACêUTICA'' A invenção refere-se a sais farmaceuticamente aceitáveis de 1-(6 -cloronaft-2-ilsulfonil)-4-[4-(4-piridil)benzoil]piperazina e forma de tamanho reduzido de partícula do composto ou de um sal farmaceuticamente aceitável do mesmo, o qual possui propriedades antitrombóticas e anticoagulantes e dessa forma são úteis em processos para o tratamento de seres humanos ou animais. A invenção também se refere a processos para a preparação de sais farmaceuticamente aceitáveis do composto acima e da forma reduzida de tamanho de partículas do mesmo, para composições farmacêuticas contendo os mesmos e para seu uso na fabricação de medicamentos para o uso na produção de um efeito antitrombótico ou anticoagulante em seres humanos.
BR9910176-9A 1998-05-02 1999-04-27 Forma de partìcula de tamanho reduzido de composto, composto, pó, uso de uma substância, e, composição farmacêutica BR9910176A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9809350.3A GB9809350D0 (en) 1998-05-02 1998-05-02 Novel salt
PCT/GB1999/001316 WO1999057112A1 (en) 1998-05-02 1999-04-27 Reduced particle size form of 1-(6-chloronaphth-2- ylsulphonyl) -4-[4-(4pyridyl) benzoyl] piperazine

Publications (1)

Publication Number Publication Date
BR9910176A true BR9910176A (pt) 2001-01-09

Family

ID=10831311

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9910176-9A BR9910176A (pt) 1998-05-02 1999-04-27 Forma de partìcula de tamanho reduzido de composto, composto, pó, uso de uma substância, e, composição farmacêutica

Country Status (16)

Country Link
EP (1) EP1084118A1 (pt)
JP (1) JP2002513789A (pt)
KR (1) KR20010043216A (pt)
CN (1) CN1308629A (pt)
AU (1) AU3719699A (pt)
BR (1) BR9910176A (pt)
CA (1) CA2331041A1 (pt)
EE (1) EE200000638A (pt)
GB (1) GB9809350D0 (pt)
HU (1) HUP0102394A3 (pt)
IL (1) IL139405A0 (pt)
NO (1) NO20005498L (pt)
PL (1) PL343705A1 (pt)
SK (1) SK16522000A3 (pt)
WO (1) WO1999057112A1 (pt)
ZA (1) ZA200006036B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9815377A (pt) 1997-09-30 2001-01-16 Daiichi Pharmaceutical Co Ltda Derivados de sulfonil
TWI288745B (en) 2000-04-05 2007-10-21 Daiichi Seiyaku Co Ethylenediamine derivatives
US7365205B2 (en) 2001-06-20 2008-04-29 Daiichi Sankyo Company, Limited Diamine derivatives
PT1569912E (pt) 2002-12-03 2015-09-15 Pharmacyclics Llc Derivados 2-(2-hidroxibifenil-3-il)-1h-benzoimidazole-5- carboxamidina como inibidores do fator viia

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA56197C2 (uk) * 1996-11-08 2003-05-15 Зенека Лімітед Гетероциклічні похідні
CA2287292A1 (en) * 1997-05-30 1998-12-03 Takeda Chemical Industries, Ltd. Sulfonamide derivatives, their production and use
BR9815377A (pt) * 1997-09-30 2001-01-16 Daiichi Pharmaceutical Co Ltda Derivados de sulfonil

Also Published As

Publication number Publication date
NO20005498D0 (no) 2000-11-01
NO20005498L (no) 2000-11-01
SK16522000A3 (sk) 2001-05-10
EP1084118A1 (en) 2001-03-21
CN1308629A (zh) 2001-08-15
PL343705A1 (en) 2001-08-27
AU3719699A (en) 1999-11-23
IL139405A0 (en) 2001-11-25
EE200000638A (et) 2002-04-15
HUP0102394A2 (hu) 2001-12-28
ZA200006036B (en) 2002-01-25
HUP0102394A3 (en) 2003-01-28
KR20010043216A (ko) 2001-05-25
JP2002513789A (ja) 2002-05-14
GB9809350D0 (en) 1998-07-01
WO1999057112A1 (en) 1999-11-11
CA2331041A1 (en) 1999-11-11

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007.