BR9909679A - Proteìna tao quinases e processos para seu uso - Google Patents
Proteìna tao quinases e processos para seu usoInfo
- Publication number
- BR9909679A BR9909679A BR9909679-0A BR9909679A BR9909679A BR 9909679 A BR9909679 A BR 9909679A BR 9909679 A BR9909679 A BR 9909679A BR 9909679 A BR9909679 A BR 9909679A
- Authority
- BR
- Brazil
- Prior art keywords
- processes
- kinases
- protect
- mitogen
- presented
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
"PROTEìNA TAO QUINASES E PROCESSOS PARA SEU USO" São apresentadas composições e processos para potencializar a atividade da proteína quinase ativada por mitógeno p38. Em particular, apresenta-se a proteína quinase ativada por mitógeno MEK3, e suas variantes, que estimulam a fosforilação de p38. Esses compostos podem ser usados, por exemplo, para a terapia de doenças associadas à cascata de p38 e para identificar anticorpos e outros agentes que inibam ou ativem a transdução de sinais mediante p38.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/060,410 US6165461A (en) | 1998-04-14 | 1998-04-14 | Tao protein kinases and methods of use therefor |
PCT/US1999/008165 WO1999053076A1 (en) | 1998-04-14 | 1999-04-14 | Tao protein kinases and methods of use therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9909679A true BR9909679A (pt) | 2000-12-19 |
Family
ID=22029289
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9909679-0A BR9909679A (pt) | 1998-04-14 | 1999-04-14 | Proteìna tao quinases e processos para seu uso |
Country Status (8)
Country | Link |
---|---|
US (2) | US6165461A (pt) |
EP (1) | EP1071787A1 (pt) |
JP (1) | JP2002515223A (pt) |
CN (1) | CN100374568C (pt) |
AU (1) | AU758731B2 (pt) |
BR (1) | BR9909679A (pt) |
CA (1) | CA2325824A1 (pt) |
WO (1) | WO1999053076A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7078182B1 (en) | 1998-04-14 | 2006-07-18 | Board Of Regents, The University Of Texas System | TAO protein kinase polypeptides and methods of use therefor |
US6165461A (en) | 1998-04-14 | 2000-12-26 | Board Of Regents, University Of Texas System | Tao protein kinases and methods of use therefor |
US7148330B2 (en) * | 1999-07-30 | 2006-12-12 | Schering Corporation | Binding compounds for IL-27 |
AU2001243556A1 (en) * | 2001-03-12 | 2002-09-24 | Alydar Pharmaceuticals, Inc. | Screening non-peptide, non-steroid invertebrate pheromone compounds for mitogen-activated protein kinase modulating activity |
US6806293B1 (en) | 2001-03-12 | 2004-10-19 | Darley Pharmaceuticals Ltd | Use of pheromone compounds having MAP kinase modulating activity |
AU2002312241A1 (en) * | 2001-06-05 | 2002-12-16 | Exelixis, Inc. | B3galts as modifiers of the p53 pathway and methods of use |
AU2002324598A1 (en) * | 2001-08-06 | 2003-02-24 | Exelixis, Inc. | Trps as modifiers of the p53 pathway and methods of use |
JP2005512529A (ja) | 2001-12-13 | 2005-05-12 | エクセリクシス・インコーポレイテッド | βカテニン経路のモディファイヤーとしてのTAOJIKsおよび使用方法 |
AU2003255337A1 (en) * | 2002-07-31 | 2004-02-23 | Kylix B.V. | Use of genes identified to be involved in tumor development for the development of anti-cancer drugs |
US7282479B2 (en) * | 2003-03-31 | 2007-10-16 | Ttc Co., Ltd. | Hyperthermia agent for malignant tumor comprising cytokine and magnetic fine particles |
EP1514558A1 (en) * | 2003-09-15 | 2005-03-16 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Use of MARKK or MARKK antagonists for the treatment of pathologies characterised by increased or reduced phosphorylation of MARK or tau protein |
US20100183583A1 (en) * | 2005-06-20 | 2010-07-22 | Exelixis, Inc. | Galk1s as modifiers of the pten/akt pathway and methods of use |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4326097A (en) * | 1996-07-03 | 1998-01-21 | Chiron Corporation | (mitogen-activated protein kinase) kinase-3 (mkk3) interacting protein (mip) |
AU8296698A (en) * | 1997-07-08 | 1999-02-08 | Cadus Pharmaceutical Corporation | (kds) protein kinase molecules and uses related thereto |
US6165461A (en) | 1998-04-14 | 2000-12-26 | Board Of Regents, University Of Texas System | Tao protein kinases and methods of use therefor |
-
1998
- 1998-04-14 US US09/060,410 patent/US6165461A/en not_active Expired - Fee Related
-
1999
- 1999-04-14 BR BR9909679-0A patent/BR9909679A/pt not_active Application Discontinuation
- 1999-04-14 CN CNB99806761XA patent/CN100374568C/zh not_active Expired - Fee Related
- 1999-04-14 AU AU35605/99A patent/AU758731B2/en not_active Ceased
- 1999-04-14 WO PCT/US1999/008165 patent/WO1999053076A1/en not_active Application Discontinuation
- 1999-04-14 EP EP99917495A patent/EP1071787A1/en not_active Withdrawn
- 1999-04-14 JP JP2000543623A patent/JP2002515223A/ja active Pending
- 1999-04-14 CA CA002325824A patent/CA2325824A1/en not_active Abandoned
-
2000
- 2000-11-27 US US09/723,458 patent/US6586242B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6586242B1 (en) | 2003-07-01 |
AU3560599A (en) | 1999-11-01 |
AU758731B2 (en) | 2003-03-27 |
CN100374568C (zh) | 2008-03-12 |
CN1303435A (zh) | 2001-07-11 |
WO1999053076A9 (en) | 2001-03-15 |
CA2325824A1 (en) | 1999-10-21 |
WO1999053076A1 (en) | 1999-10-21 |
JP2002515223A (ja) | 2002-05-28 |
US6165461A (en) | 2000-12-26 |
EP1071787A1 (en) | 2001-01-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. PORTANTO, INDEFIRO O PRESENTE PEDIDO DE PATENTE COMO INVENCAO - DE ACORDO COM OS ARTIGOS 8O, 10 (VIII), 10 (IX), 13, 18 (III), 24 E 25 DA LPI. |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |